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The map label for this gene is hlyB [H]

Identifier: 218709795

GI number: 218709795

Start: 1937411

End: 1939045

Strand: Direct

Name: hlyB [H]

Synonym: VS_1807

Alternate gene names: 218709795

Gene position: 1937411-1939045 (Clockwise)

Preceding gene: 218709792

Following gene: 218709797

Centisome position: 58.72

GC content: 45.2

Gene sequence:

>1635_bases
ATGCGCTCAACAATCACCTTTAAAATCCTAGTAGCCCTCGCCATTGTGTTCACTTTCTTGCTTGCAATATCGACTTACTT
TCAATATTCGCAGCAAAAGCAACTTGTAAACTCGGTGTTAAGTGAGCAGCTTCACGATAAGGCAAGCAACTATTTCGATA
GCCTTAATATGATGATGCTGACTGGCACCATGGCACAAAAAGAGACCCTTCGTCAGAAAGCGTTAGCGCAAGAAGGCATT
GAAAATGTTCGTGTACTGCGCGCCGATGCAGTGAGCAAATTGTACGGACCTGGCAATGACAACCAAACACCTATTGATGA
TATCGATAAACGAGCGCTAGCAGGCGAAACTGTTATCGAACCCTTTTCTGCCGATTGGGGTAAAGGCTTGGTTATTGCTC
TGCCAATGAAGTCGAGTGAAGATTATCGAGGTACCAATTGTGTCGCCTGTCATATGGCACCAGAAGGTGAAGTATTAGGC
GCGATTCGCCTAGAATATAACCTCAGCCACGTTAACGCGCTGATCAACACTCAAACCATGGCTGCTATAGGCATTATGGC
GGTTATCTCCTTCGCCGGGTTTGTTCTTACGATGGGATTAATTCGTAAGATTATCGTTCGCCCTCTTCAACAGACTTCGC
GGTTTATGACCCAAGTAAGCAGCGATAAAAACCTGTCCACTCGTTTGCCCGAACAAAGTAAAGATGAGATTGGCACGCTG
GCTAACGCCATCAACTCGTTCATGGGAACCGTTTCTAACAGCTTAGAAAAGGTACAAGATACTTCGCACAAACTGAATGC
GTCAGCCAATCAACTGACTAGCGTTGCTCAAATTACCGAGCAAGCCGCCTGCGATCAACAAAACGAAACCACAGAAGTGC
AAAACAATGTCGAAGGAATACAAGCACAACAGGTCAATGTAGAACAAGCCACTTTAACCGCGTCAGAACTCATCAATCAC
ACCTCAGATGTGGCTTGTAAGAGTGCTAACCAAGCACATGATGCAAGTAGTGAGATTAAGAATCTAGTGAGCAGTATCGA
AGAAGTGAAACACAAGATACAAACACTTAATGAGCAAACTGGAGAAGTCTCTTCAATATTGAGTGTGATTCGTGGCATTG
CCGACCAAACCAACCTTCTAGCCTTGAATGCAGCGATTGAAGCGGCTCGAGCGGGAGAACAAGGTCGCGGCTTTGCGGTA
GTGGCAGATGAAGTTCGTAATCTTGCATCACGAACGGCAGAGGCTACTGGCAGTATTGAGTCTATCATTCATCAGTTCCA
ACAAGGCAGTGAAGAATCGCTGAATTCTGCTGACCGCGTTTGCGAACAAGCACATCAAAGCTCGACAGATATCGACGCAC
TGTCCGTTGAAATGAACGGTGTCGTTGAAGAAATGAAACAAGTGTTAGCTCATGCACAAAATATTCAGCAACAGACGCAA
TCCACCACACAAGCAACCCAAGATGTGCAACAAAAAGTTGAAACCATCACTTCTCACGCCGACAACACATCGCAGTCTGC
AGCTGAAACTCGTGGAATCAGTAATGATTTAGAAGATCTGTCGGATCACCTTGAATCTCTTATCAACCAATTCACCTTAT
CGAACTCAAATACCAACGATAAAGGTCAGTCATAG

Upstream 100 bases:

>100_bases
AACCGGAGTGTGGTCACACAATCGGTTATACCCCATAGGTGGTAGAGCCGCTTACACGTAAAGTATGCATGTCATTATAC
TTAATAAAAACAAACACCTT

Downstream 100 bases:

>100_bases
GCCGTTAGAACTCCCCTAGCGACATCAACAAAAAAGCGCTCAAAGATGAGCGCTTTATCTTCATAACAATGTCTAGTTTG
GGCTTTAAGATTTTAAGATT

Product: methyl-accepting chemotaxis protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 544; Mature: 544

Protein sequence:

>544_residues
MRSTITFKILVALAIVFTFLLAISTYFQYSQQKQLVNSVLSEQLHDKASNYFDSLNMMMLTGTMAQKETLRQKALAQEGI
ENVRVLRADAVSKLYGPGNDNQTPIDDIDKRALAGETVIEPFSADWGKGLVIALPMKSSEDYRGTNCVACHMAPEGEVLG
AIRLEYNLSHVNALINTQTMAAIGIMAVISFAGFVLTMGLIRKIIVRPLQQTSRFMTQVSSDKNLSTRLPEQSKDEIGTL
ANAINSFMGTVSNSLEKVQDTSHKLNASANQLTSVAQITEQAACDQQNETTEVQNNVEGIQAQQVNVEQATLTASELINH
TSDVACKSANQAHDASSEIKNLVSSIEEVKHKIQTLNEQTGEVSSILSVIRGIADQTNLLALNAAIEAARAGEQGRGFAV
VADEVRNLASRTAEATGSIESIIHQFQQGSEESLNSADRVCEQAHQSSTDIDALSVEMNGVVEEMKQVLAHAQNIQQQTQ
STTQATQDVQQKVETITSHADNTSQSAAETRGISNDLEDLSDHLESLINQFTLSNSNTNDKGQS

Sequences:

>Translated_544_residues
MRSTITFKILVALAIVFTFLLAISTYFQYSQQKQLVNSVLSEQLHDKASNYFDSLNMMMLTGTMAQKETLRQKALAQEGI
ENVRVLRADAVSKLYGPGNDNQTPIDDIDKRALAGETVIEPFSADWGKGLVIALPMKSSEDYRGTNCVACHMAPEGEVLG
AIRLEYNLSHVNALINTQTMAAIGIMAVISFAGFVLTMGLIRKIIVRPLQQTSRFMTQVSSDKNLSTRLPEQSKDEIGTL
ANAINSFMGTVSNSLEKVQDTSHKLNASANQLTSVAQITEQAACDQQNETTEVQNNVEGIQAQQVNVEQATLTASELINH
TSDVACKSANQAHDASSEIKNLVSSIEEVKHKIQTLNEQTGEVSSILSVIRGIADQTNLLALNAAIEAARAGEQGRGFAV
VADEVRNLASRTAEATGSIESIIHQFQQGSEESLNSADRVCEQAHQSSTDIDALSVEMNGVVEEMKQVLAHAQNIQQQTQ
STTQATQDVQQKVETITSHADNTSQSAAETRGISNDLEDLSDHLESLINQFTLSNSNTNDKGQS
>Mature_544_residues
MRSTITFKILVALAIVFTFLLAISTYFQYSQQKQLVNSVLSEQLHDKASNYFDSLNMMMLTGTMAQKETLRQKALAQEGI
ENVRVLRADAVSKLYGPGNDNQTPIDDIDKRALAGETVIEPFSADWGKGLVIALPMKSSEDYRGTNCVACHMAPEGEVLG
AIRLEYNLSHVNALINTQTMAAIGIMAVISFAGFVLTMGLIRKIIVRPLQQTSRFMTQVSSDKNLSTRLPEQSKDEIGTL
ANAINSFMGTVSNSLEKVQDTSHKLNASANQLTSVAQITEQAACDQQNETTEVQNNVEGIQAQQVNVEQATLTASELINH
TSDVACKSANQAHDASSEIKNLVSSIEEVKHKIQTLNEQTGEVSSILSVIRGIADQTNLLALNAAIEAARAGEQGRGFAV
VADEVRNLASRTAEATGSIESIIHQFQQGSEESLNSADRVCEQAHQSSTDIDALSVEMNGVVEEMKQVLAHAQNIQQQTQ
STTQATQDVQQKVETITSHADNTSQSAAETRGISNDLEDLSDHLESLINQFTLSNSNTNDKGQS

Specific function: May form a pore through which the hemolysin can be exported [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell outer membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI1788194, Length=370, Percent_Identity=29.7297297297297, Blast_Score=109, Evalue=6e-25,
Organism=Escherichia coli, GI1787690, Length=315, Percent_Identity=30.1587301587302, Blast_Score=108, Evalue=8e-25,
Organism=Escherichia coli, GI1788195, Length=223, Percent_Identity=31.390134529148, Blast_Score=106, Evalue=4e-24,
Organism=Escherichia coli, GI2367378, Length=245, Percent_Identity=29.3877551020408, Blast_Score=99, Evalue=7e-22,
Organism=Escherichia coli, GI1789453, Length=242, Percent_Identity=31.404958677686, Blast_Score=92, Evalue=9e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660
- InterPro:   IPR000727 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 59049; Mature: 59049

Theoretical pI: Translated: 4.59; Mature: 4.59

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRSTITFKILVALAIVFTFLLAISTYFQYSQQKQLVNSVLSEQLHDKASNYFDSLNMMML
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TGTMAQKETLRQKALAQEGIENVRVLRADAVSKLYGPGNDNQTPIDDIDKRALAGETVIE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCHHHC
PFSADWGKGLVIALPMKSSEDYRGTNCVACHMAPEGEVLGAIRLEYNLSHVNALINTQTM
CCCCCCCCCEEEEEECCCCCCCCCCCEEEEEECCCCCEEEEEEEEECHHHHHHHHHHHHH
AAIGIMAVISFAGFVLTMGLIRKIIVRPLQQTSRFMTQVSSDKNLSTRLPEQSKDEIGTL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHCCCCCCHHHHHHH
ANAINSFMGTVSNSLEKVQDTSHKLNASANQLTSVAQITEQAACDQQNETTEVQNNVEGI
HHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCC
QAQQVNVEQATLTASELINHTSDVACKSANQAHDASSEIKNLVSSIEEVKHKIQTLNEQT
HHHHCCHHHHHHHHHHHHHHHHHHHHHCCCHHCCHHHHHHHHHHHHHHHHHHHHHHHHCC
GEVSSILSVIRGIADQTNLLALNAAIEAARAGEQGRGFAVVADEVRNLASRTAEATGSIE
CHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCEEEEHHHHHHHHHHHHHHCCHHH
SIIHQFQQGSEESLNSADRVCEQAHQSSTDIDALSVEMNGVVEEMKQVLAHAQNIQQQTQ
HHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
STTQATQDVQQKVETITSHADNTSQSAAETRGISNDLEDLSDHLESLINQFTLSNSNTND
HHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCC
KGQS
CCCC
>Mature Secondary Structure
MRSTITFKILVALAIVFTFLLAISTYFQYSQQKQLVNSVLSEQLHDKASNYFDSLNMMML
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TGTMAQKETLRQKALAQEGIENVRVLRADAVSKLYGPGNDNQTPIDDIDKRALAGETVIE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCHHHC
PFSADWGKGLVIALPMKSSEDYRGTNCVACHMAPEGEVLGAIRLEYNLSHVNALINTQTM
CCCCCCCCCEEEEEECCCCCCCCCCCEEEEEECCCCCEEEEEEEEECHHHHHHHHHHHHH
AAIGIMAVISFAGFVLTMGLIRKIIVRPLQQTSRFMTQVSSDKNLSTRLPEQSKDEIGTL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHCCCCCCHHHHHHH
ANAINSFMGTVSNSLEKVQDTSHKLNASANQLTSVAQITEQAACDQQNETTEVQNNVEGI
HHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCC
QAQQVNVEQATLTASELINHTSDVACKSANQAHDASSEIKNLVSSIEEVKHKIQTLNEQT
HHHHCCHHHHHHHHHHHHHHHHHHHHHCCCHHCCHHHHHHHHHHHHHHHHHHHHHHHHCC
GEVSSILSVIRGIADQTNLLALNAAIEAARAGEQGRGFAVVADEVRNLASRTAEATGSIE
CHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCEEEEHHHHHHHHHHHHHHCCHHH
SIIHQFQQGSEESLNSADRVCEQAHQSSTDIDALSVEMNGVVEEMKQVLAHAQNIQQQTQ
HHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
STTQATQDVQQKVETITSHADNTSQSAAETRGISNDLEDLSDHLESLINQFTLSNSNTND
HHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCC
KGQS
CCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2162464; 10952301 [H]