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The map label for this gene is pabB [H]

Identifier: 218709786

GI number: 218709786

Start: 1926199

End: 1927605

Strand: Direct

Name: pabB [H]

Synonym: VS_1798

Alternate gene names: 218709786

Gene position: 1926199-1927605 (Clockwise)

Preceding gene: 218709777

Following gene: 218709790

Centisome position: 58.38

GC content: 45.77

Gene sequence:

>1407_bases
ATGAATAACAACGAATTTCGCTCTATCCAAATCAAGCCGCTTGAATATCAATCAACTTTAGCTAAACAGCTGTTTTCTCA
TATTGAAAGCGTGCCGTGGGCAATGCTATTACGCTCTGCCTCAGAAAGCCACGTCGATAGTCGATACGACATTTTAGTTG
CTCAACCCATCGCCACCTTCGAGACAATCGGTGCAAAAACGACCGTCAATGTTAATGAGACGTGCGAGGTTTCAGAGTCA
GACCCTTTCGAACTACTCGACCAATATCAGCAGCAATTACTACCCGCAATCAGTGAGCACCCTGAACTGCCTTTCGTTGG
TGGTGCTTTAGGGTATTTTAGTTACGATTTAGGGCGACGAGTAGAAGCTCTTCCCTCTCTTGCTAAGCGTGATATTTCTG
CACCAGACATGGCGGTTGGATTGTATGAATGGGCTGTGATTGTTGATCATAAGCTTAAAGCTGCGTTCCTTGTTGGGCAA
AACATTGATACCCATTGGGATTGGTTAACTCAACAACAATCGCCAAGCCAACAAGCAGAAAGAGCGGAACAAACAGAACG
AGCTCGTCAGAAGTTTGGATTAACCACTCCATGGCAATCCAATATGACAGAACAAAGTTATGCCAATAAATTCGATAGCG
TTCAAGAGTACTTGTTGTCGGGTGACTGTTATCAGATAAACCTTGCTCAGCGCTTCAATGCCCAATACCAAGGCAGTGAA
TGGCTCGCTTATGAAAAGTTAGAGAAATACAACTCAGCTCCATTCTCTGGTTTTATCCGTTTAGCAGGCTGCACCATTCT
CAGTGTCTCACCTGAGCGTTTTTTAGAGCTCAATAGTGGCACCATTGAAACCAAGCCAATCAAAGGGACACGTCCTCGTT
CTGAAAATTCCATGATTGATGACGCCAATGCTCAAGACCTGTTAACTGCTGAGAAAGATCAGGCGGAAAACCTGATGATT
GTCGACCTGCTTCGTAATGATATTGGCCGAGTCGCAAAGCCGGGATCGGTTCATGTACCAAAGCTCTTCGATATAGAGAG
TTTCCCTGCTGTGCACCACTTAGTGAGCACGATAAGGGCAGAGCTTGATGTCCATCATTCAGCACATGACCTATTAAGGG
CTTGCTTTCCCGGGGGGTCGATTACCGGCGCTCCAAAAGTTCGCGCGATGCAGATCATTGAGGAGCTAGAGCCTCATCGT
CGCTCGGCGTATTGCGGTAGCATTGGTTATATCAGCCGTAATGGCAGAATGGACACCAGCATTACGATTCGTACGTTAGT
GGCAGAAAACAATACGCTTTATGCTTGGGCTGGAGGAGGTGTAGTATTTGATAGTGATTGTGCTTCTGAGTACCAAGAGA
CTCTTGATAAGCTGAGTAGAATATTGCCTGTACTGGCTGATAGATAA

Upstream 100 bases:

>100_bases
ACCGTTCTAATCAAGAACCCATTTTATTTTCAATTTATGATACTCTTGCTTCCTCTCACACGCCATGCAGTGATCGAACT
CTTTGTCACAAATTAAACAA

Downstream 100 bases:

>100_bases
ATTTAATCTAGATTTATTAAAACGGGTTATTAAAAACAGCTAAAAAACCAATCTGGAAAGTACTTTAATATTAAAAAAGC
TAAGTGGGCAATCACCTACT

Product: para-aminobenzoate synthase component I

Products: NA

Alternate protein names: ADC synthase; Para-aminobenzoate synthase component I [H]

Number of amino acids: Translated: 468; Mature: 468

Protein sequence:

>468_residues
MNNNEFRSIQIKPLEYQSTLAKQLFSHIESVPWAMLLRSASESHVDSRYDILVAQPIATFETIGAKTTVNVNETCEVSES
DPFELLDQYQQQLLPAISEHPELPFVGGALGYFSYDLGRRVEALPSLAKRDISAPDMAVGLYEWAVIVDHKLKAAFLVGQ
NIDTHWDWLTQQQSPSQQAERAEQTERARQKFGLTTPWQSNMTEQSYANKFDSVQEYLLSGDCYQINLAQRFNAQYQGSE
WLAYEKLEKYNSAPFSGFIRLAGCTILSVSPERFLELNSGTIETKPIKGTRPRSENSMIDDANAQDLLTAEKDQAENLMI
VDLLRNDIGRVAKPGSVHVPKLFDIESFPAVHHLVSTIRAELDVHHSAHDLLRACFPGGSITGAPKVRAMQIIEELEPHR
RSAYCGSIGYISRNGRMDTSITIRTLVAENNTLYAWAGGGVVFDSDCASEYQETLDKLSRILPVLADR

Sequences:

>Translated_468_residues
MNNNEFRSIQIKPLEYQSTLAKQLFSHIESVPWAMLLRSASESHVDSRYDILVAQPIATFETIGAKTTVNVNETCEVSES
DPFELLDQYQQQLLPAISEHPELPFVGGALGYFSYDLGRRVEALPSLAKRDISAPDMAVGLYEWAVIVDHKLKAAFLVGQ
NIDTHWDWLTQQQSPSQQAERAEQTERARQKFGLTTPWQSNMTEQSYANKFDSVQEYLLSGDCYQINLAQRFNAQYQGSE
WLAYEKLEKYNSAPFSGFIRLAGCTILSVSPERFLELNSGTIETKPIKGTRPRSENSMIDDANAQDLLTAEKDQAENLMI
VDLLRNDIGRVAKPGSVHVPKLFDIESFPAVHHLVSTIRAELDVHHSAHDLLRACFPGGSITGAPKVRAMQIIEELEPHR
RSAYCGSIGYISRNGRMDTSITIRTLVAENNTLYAWAGGGVVFDSDCASEYQETLDKLSRILPVLADR
>Mature_468_residues
MNNNEFRSIQIKPLEYQSTLAKQLFSHIESVPWAMLLRSASESHVDSRYDILVAQPIATFETIGAKTTVNVNETCEVSES
DPFELLDQYQQQLLPAISEHPELPFVGGALGYFSYDLGRRVEALPSLAKRDISAPDMAVGLYEWAVIVDHKLKAAFLVGQ
NIDTHWDWLTQQQSPSQQAERAEQTERARQKFGLTTPWQSNMTEQSYANKFDSVQEYLLSGDCYQINLAQRFNAQYQGSE
WLAYEKLEKYNSAPFSGFIRLAGCTILSVSPERFLELNSGTIETKPIKGTRPRSENSMIDDANAQDLLTAEKDQAENLMI
VDLLRNDIGRVAKPGSVHVPKLFDIESFPAVHHLVSTIRAELDVHHSAHDLLRACFPGGSITGAPKVRAMQIIEELEPHR
RSAYCGSIGYISRNGRMDTSITIRTLVAENNTLYAWAGGGVVFDSDCASEYQETLDKLSRILPVLADR

Specific function: Catalyzes the biosynthesis of 4-amino-4-deoxychorismate (ADC) from chorismate and glutamine [H]

COG id: COG0147

COG function: function code EH; Anthranilate/para-aminobenzoate synthases component I

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the anthranilate synthase component I family [H]

Homologues:

Organism=Escherichia coli, GI1788114, Length=453, Percent_Identity=53.6423841059603, Blast_Score=473, Evalue=1e-134,
Organism=Escherichia coli, GI1787518, Length=403, Percent_Identity=33.4987593052109, Blast_Score=192, Evalue=4e-50,
Organism=Escherichia coli, GI1786809, Length=223, Percent_Identity=26.9058295964126, Blast_Score=89, Evalue=6e-19,
Organism=Escherichia coli, GI87082077, Length=206, Percent_Identity=27.1844660194175, Blast_Score=67, Evalue=4e-12,
Organism=Saccharomyces cerevisiae, GI6320935, Length=439, Percent_Identity=31.6628701594533, Blast_Score=202, Evalue=1e-52,
Organism=Saccharomyces cerevisiae, GI6324361, Length=420, Percent_Identity=26.9047619047619, Blast_Score=142, Evalue=9e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005801
- InterPro:   IPR019999
- InterPro:   IPR006805
- InterPro:   IPR015890
- InterPro:   IPR005802 [H]

Pfam domain/function: PF04715 Anth_synt_I_N; PF00425 Chorismate_bind [H]

EC number: =2.6.1.85 [H]

Molecular weight: Translated: 52466; Mature: 52466

Theoretical pI: Translated: 4.96; Mature: 4.96

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNNNEFRSIQIKPLEYQSTLAKQLFSHIESVPWAMLLRSASESHVDSRYDILVAQPIATF
CCCCCEEEEEEECCHHHHHHHHHHHHHHHHCCHHHHHHHCCHHCCCCCEEEEEECCHHHH
ETIGAKTTVNVNETCEVSESDPFELLDQYQQQLLPAISEHPELPFVGGALGYFSYDLGRR
HHCCCCEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCEECCHHHHHHHHHHHH
VEALPSLAKRDISAPDMAVGLYEWAVIVDHKLKAAFLVGQNIDTHWDWLTQQQSPSQQAE
HHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCEEEEEECCCCCCHHHHHHCCCCCHHHHH
RAEQTERARQKFGLTTPWQSNMTEQSYANKFDSVQEYLLSGDCYQINLAQRFNAQYQGSE
HHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEEHHHHCCCCCCCCC
WLAYEKLEKYNSAPFSGFIRLAGCTILSVSPERFLELNSGTIETKPIKGTRPRSENSMID
HHHHHHHHHHCCCCHHHHHHHHCEEEEEECHHHHEEECCCEEEECCCCCCCCCCCCCCCC
DANAQDLLTAEKDQAENLMIVDLLRNDIGRVAKPGSVHVPKLFDIESFPAVHHLVSTIRA
CCCCHHHHHCCCCCCCCEEHHHHHHHHHHHCCCCCCCCCCEEECCCCCHHHHHHHHHHHH
ELDVHHSAHDLLRACFPGGSITGAPKVRAMQIIEELEPHRRSAYCGSIGYISRNGRMDTS
HHHCCCCHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCHHHHHHCCCCCCEEECCCCCCCE
ITIRTLVAENNTLYAWAGGGVVFDSDCASEYQETLDKLSRILPVLADR
EEEEEEEECCCEEEEEECCCEEECCHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MNNNEFRSIQIKPLEYQSTLAKQLFSHIESVPWAMLLRSASESHVDSRYDILVAQPIATF
CCCCCEEEEEEECCHHHHHHHHHHHHHHHHCCHHHHHHHCCHHCCCCCEEEEEECCHHHH
ETIGAKTTVNVNETCEVSESDPFELLDQYQQQLLPAISEHPELPFVGGALGYFSYDLGRR
HHCCCCEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCEECCHHHHHHHHHHHH
VEALPSLAKRDISAPDMAVGLYEWAVIVDHKLKAAFLVGQNIDTHWDWLTQQQSPSQQAE
HHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCEEEEEECCCCCCHHHHHHCCCCCHHHHH
RAEQTERARQKFGLTTPWQSNMTEQSYANKFDSVQEYLLSGDCYQINLAQRFNAQYQGSE
HHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEEHHHHCCCCCCCCC
WLAYEKLEKYNSAPFSGFIRLAGCTILSVSPERFLELNSGTIETKPIKGTRPRSENSMID
HHHHHHHHHHCCCCHHHHHHHHCEEEEEECHHHHEEECCCEEEECCCCCCCCCCCCCCCC
DANAQDLLTAEKDQAENLMIVDLLRNDIGRVAKPGSVHVPKLFDIESFPAVHHLVSTIRA
CCCCHHHHHCCCCCCCCEEHHHHHHHHHHHCCCCCCCCCCEEECCCCCHHHHHHHHHHHH
ELDVHHSAHDLLRACFPGGSITGAPKVRAMQIIEELEPHRRSAYCGSIGYISRNGRMDTS
HHHCCCCHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCHHHHHHCCCCCCEEECCCCCCCE
ITIRTLVAENNTLYAWAGGGVVFDSDCASEYQETLDKLSRILPVLADR
EEEEEEEECCCEEEEEECCCEEECCHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 3057324; 2251281 [H]