Click here to switch to the map view.

The map label for this gene is glpT [H]

Identifier: 218709602

GI number: 218709602

Start: 1728230

End: 1729603

Strand: Reverse

Name: glpT [H]

Synonym: VS_1612

Alternate gene names: 218709602

Gene position: 1729603-1728230 (Counterclockwise)

Preceding gene: 218709605

Following gene: 218709601

Centisome position: 52.42

GC content: 46.87

Gene sequence:

>1374_bases
ATGTTTGGAATATTCAAACCTATGGCGCATATCGATCGCTTGTCATCAGATAAGATCGATAGCACCTACACACGACTACG
ATGGCAGCTGTTTCTCGGCATCTTCGTTGGCTATGCGGGGTATTACTTAGTCCGTAAAAACTTTAGTTTGGCGATGCCTT
ATCTCATTGAACAAGGTTTTAGCCGCGGAGAACTAGGGGTTGCATTAGCGGCGGTATCTATCGCTTACGGCTTATCTAAG
TTCTTAATGGGCAGTGTTTCTGACCGTTCTAACCCCCGATACTTTCTCAGCGGTGGCTTGTTAATGTCGGCATTGGTCAT
GTTCTGCTTCGGCTTCATGCCTTGGGCAACAGGCAGCATCACTGCGATGTTTATTCTGCTGTTCTTGAATGGTTGGTTCC
AAGGTATGGGTTGGCCAGCTTGTGGACGAACCATGGTTCACTGGTGGTCACGAAAAGAACGTGGTGAGATCGTATCGGTA
TGGAACGTTGCTCACAACGTGGGTGGCGGTTTGATTGGCCCAATGTTCTTGTTGGGGCTGTGGGCTTTTAACGACGATTG
GCGAACCGCTTTTTATGTTCCTGCATTTTTTGCCACTCTCGTTTCTGTCTTTGTTTGGTTTACTGTAAGAGATACACCTC
AATCTTGCGGCTTACCACCGATTGAAGAACACAAAGATGATTACCCAGACGACTACGATACGTCTCATGAGAAAGAAATG
ACGGCGAAAGAGATCTTCTTTAAGTACGTTTTCTCTAACAAGCTGTTGTGGTCAATCGCGATTGCTAATGCGTTTGTTTA
CCTTATCCGTTATGGCGTACTCGATTGGGCTCCGGTTTACTTAAAAGAAGCGAAAGACTTCTCTGTAGATAAATCCTCTT
GGGCCTACTTCCTGTATGAGTGGGCAGGTATTCCTGGCACGTTATTGTGTGGTTGGATTTCAGATAAATTATTCAAAGGT
CGACGAGCACCTGCAGGTATCTTGTTCATGGTTCTAGTGACAGTCGCTGTGTTGGTATATTGGCTGAACCCTGCGGGTAA
CCCAACGGTTGATATGTTGGCACTGGTTGCGATTGGTTTCCTTATCTATGGTCCTGTAATGCTGATCGGTTTGTATGCAC
TGGAACTTGCACCTAAGAAAGCTGCAGGTACTGCCGCTGGTCTAACAGGTTTGTTTGGTTACTTAGGTGGCGCGGTTGCC
GCGAACGCAATTCTCGGCTTTATGGTTGACCATTACGGCTGGGATGGCGGCTTCATTATTTTGGTCGGCGCTTGTGTGGC
TTCAATCATCTGTCTGCTTTACGCCTTCTTAGGTGAACGTGCGCACCACAAACAAAAAGATCTCGAACGAGAGAAAGAAG
CGCTAGCTCAGTAG

Upstream 100 bases:

>100_bases
AATCCTGATGCACATACAATTCCCTTTATTTCGAATGAGCGCTAAATTTTTTCGTTCGAGCATTTAAATTCTTCCTTCGC
CCAATAATTATGAGGTTCCC

Downstream 100 bases:

>100_bases
TGTATTTACTGAATCACATCTATAAATAACAACAGAGGCAGGTATATCCTGCTTCTGTTTTATCAAGGGGAAACAATAAT
GAAAACAACGTCACTGTCTC

Product: sn-glycerol-3-phosphate transporter

Products: Proton [Cytoplasm]; glycerol-3-phosphate [Cytoplasm] [C]

Alternate protein names: G-3-P transporter; G-3-P permease [H]

Number of amino acids: Translated: 457; Mature: 457

Protein sequence:

>457_residues
MFGIFKPMAHIDRLSSDKIDSTYTRLRWQLFLGIFVGYAGYYLVRKNFSLAMPYLIEQGFSRGELGVALAAVSIAYGLSK
FLMGSVSDRSNPRYFLSGGLLMSALVMFCFGFMPWATGSITAMFILLFLNGWFQGMGWPACGRTMVHWWSRKERGEIVSV
WNVAHNVGGGLIGPMFLLGLWAFNDDWRTAFYVPAFFATLVSVFVWFTVRDTPQSCGLPPIEEHKDDYPDDYDTSHEKEM
TAKEIFFKYVFSNKLLWSIAIANAFVYLIRYGVLDWAPVYLKEAKDFSVDKSSWAYFLYEWAGIPGTLLCGWISDKLFKG
RRAPAGILFMVLVTVAVLVYWLNPAGNPTVDMLALVAIGFLIYGPVMLIGLYALELAPKKAAGTAAGLTGLFGYLGGAVA
ANAILGFMVDHYGWDGGFIILVGACVASIICLLYAFLGERAHHKQKDLEREKEALAQ

Sequences:

>Translated_457_residues
MFGIFKPMAHIDRLSSDKIDSTYTRLRWQLFLGIFVGYAGYYLVRKNFSLAMPYLIEQGFSRGELGVALAAVSIAYGLSK
FLMGSVSDRSNPRYFLSGGLLMSALVMFCFGFMPWATGSITAMFILLFLNGWFQGMGWPACGRTMVHWWSRKERGEIVSV
WNVAHNVGGGLIGPMFLLGLWAFNDDWRTAFYVPAFFATLVSVFVWFTVRDTPQSCGLPPIEEHKDDYPDDYDTSHEKEM
TAKEIFFKYVFSNKLLWSIAIANAFVYLIRYGVLDWAPVYLKEAKDFSVDKSSWAYFLYEWAGIPGTLLCGWISDKLFKG
RRAPAGILFMVLVTVAVLVYWLNPAGNPTVDMLALVAIGFLIYGPVMLIGLYALELAPKKAAGTAAGLTGLFGYLGGAVA
ANAILGFMVDHYGWDGGFIILVGACVASIICLLYAFLGERAHHKQKDLEREKEALAQ
>Mature_457_residues
MFGIFKPMAHIDRLSSDKIDSTYTRLRWQLFLGIFVGYAGYYLVRKNFSLAMPYLIEQGFSRGELGVALAAVSIAYGLSK
FLMGSVSDRSNPRYFLSGGLLMSALVMFCFGFMPWATGSITAMFILLFLNGWFQGMGWPACGRTMVHWWSRKERGEIVSV
WNVAHNVGGGLIGPMFLLGLWAFNDDWRTAFYVPAFFATLVSVFVWFTVRDTPQSCGLPPIEEHKDDYPDDYDTSHEKEM
TAKEIFFKYVFSNKLLWSIAIANAFVYLIRYGVLDWAPVYLKEAKDFSVDKSSWAYFLYEWAGIPGTLLCGWISDKLFKG
RRAPAGILFMVLVTVAVLVYWLNPAGNPTVDMLALVAIGFLIYGPVMLIGLYALELAPKKAAGTAAGLTGLFGYLGGAVA
ANAILGFMVDHYGWDGGFIILVGACVASIICLLYAFLGERAHHKQKDLEREKEALAQ

Specific function: Responsible for glycerol-3-phosphate uptake [H]

COG id: COG2271

COG function: function code G; Sugar phosphate permease

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Organophosphate:Pi antiporter (OPA) (TC 2.A.1.4) family [H]

Homologues:

Organism=Homo sapiens, GI256219598, Length=443, Percent_Identity=28.2167042889391, Blast_Score=152, Evalue=5e-37,
Organism=Homo sapiens, GI4503847, Length=443, Percent_Identity=28.2167042889391, Blast_Score=152, Evalue=5e-37,
Organism=Homo sapiens, GI256219483, Length=443, Percent_Identity=28.2167042889391, Blast_Score=152, Evalue=5e-37,
Organism=Homo sapiens, GI256219543, Length=465, Percent_Identity=26.8817204301075, Blast_Score=144, Evalue=2e-34,
Organism=Homo sapiens, GI256219564, Length=374, Percent_Identity=26.2032085561497, Blast_Score=108, Evalue=1e-23,
Organism=Homo sapiens, GI38093649, Length=401, Percent_Identity=25.1870324189526, Blast_Score=96, Evalue=6e-20,
Organism=Homo sapiens, GI223717983, Length=401, Percent_Identity=25.1870324189526, Blast_Score=96, Evalue=7e-20,
Organism=Homo sapiens, GI46361976, Length=411, Percent_Identity=26.5206812652068, Blast_Score=94, Evalue=2e-19,
Organism=Homo sapiens, GI14150047, Length=242, Percent_Identity=26.0330578512397, Blast_Score=68, Evalue=2e-11,
Organism=Escherichia coli, GI1788573, Length=451, Percent_Identity=68.5144124168514, Blast_Score=659, Evalue=0.0,
Organism=Escherichia coli, GI87082310, Length=423, Percent_Identity=36.8794326241135, Blast_Score=266, Evalue=2e-72,
Organism=Escherichia coli, GI2367259, Length=435, Percent_Identity=32.8735632183908, Blast_Score=202, Evalue=4e-53,
Organism=Escherichia coli, GI1789515, Length=451, Percent_Identity=23.9467849223947, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI1789152, Length=433, Percent_Identity=24.7113163972286, Blast_Score=82, Evalue=6e-17,
Organism=Escherichia coli, GI87082320, Length=442, Percent_Identity=25.1131221719457, Blast_Score=75, Evalue=7e-15,
Organism=Escherichia coli, GI2367379, Length=440, Percent_Identity=23.1818181818182, Blast_Score=68, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI133930953, Length=484, Percent_Identity=24.5867768595041, Blast_Score=114, Evalue=8e-26,
Organism=Caenorhabditis elegans, GI133901856, Length=485, Percent_Identity=25.5670103092783, Blast_Score=112, Evalue=3e-25,
Organism=Caenorhabditis elegans, GI133901854, Length=485, Percent_Identity=25.5670103092783, Blast_Score=112, Evalue=3e-25,
Organism=Caenorhabditis elegans, GI17542316, Length=477, Percent_Identity=22.4318658280922, Blast_Score=99, Evalue=5e-21,
Organism=Caenorhabditis elegans, GI17564202, Length=426, Percent_Identity=23.943661971831, Blast_Score=98, Evalue=9e-21,
Organism=Caenorhabditis elegans, GI17564204, Length=357, Percent_Identity=24.6498599439776, Blast_Score=98, Evalue=1e-20,
Organism=Drosophila melanogaster, GI24656861, Length=515, Percent_Identity=21.747572815534, Blast_Score=102, Evalue=4e-22,
Organism=Drosophila melanogaster, GI24656866, Length=515, Percent_Identity=21.747572815534, Blast_Score=102, Evalue=5e-22,
Organism=Drosophila melanogaster, GI45550478, Length=515, Percent_Identity=21.747572815534, Blast_Score=102, Evalue=5e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005267
- InterPro:   IPR000849
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196
- InterPro:   IPR021159 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 50964; Mature: 50964

Theoretical pI: Translated: 7.84; Mature: 7.84

Prosite motif: PS00018 EF_HAND_1 ; PS50850 MFS ; PS00942 GLPT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure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HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; glycerol-3-phosphate [Periplasm] [C]

Specific reaction: Proton [Periplasm] + glycerol-3-phosphate [Periplasm] = Proton [Cytoplasm] + glycerol-3-phosphate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 3329281; 9205837; 9278503; 3141744; 12893936 [H]