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The map label for this gene is mrp [H]

Identifier: 218709004

GI number: 218709004

Start: 1048281

End: 1049357

Strand: Direct

Name: mrp [H]

Synonym: VS_1010

Alternate gene names: 218709004

Gene position: 1048281-1049357 (Clockwise)

Preceding gene: 218709001

Following gene: 218709005

Centisome position: 31.77

GC content: 47.91

Gene sequence:

>1077_bases
ATGCGTAACTTTACTTCTAAGCAAGATTTCTGTTCATGGTTGAATGAGTTCGAGTCACCAATCCTCATCCCAGAGTGGGC
GCTACACCAAAATATTGTATCGGTTGATCCGCGTGGATCATTCGTTATCACCTTGCCTTTTGCTGCGAATCAGCTCGCGA
TTGAACTGGAACAGTGGATCCACTCCCAGATTGAACAGCAACTTGTTAGTGCTTTTCAGTTTGAAGTAAAAGTGAAGCCG
TCTGCGCTAGAAACAACAGTCGCGACACCTTTGAAGGGTGTTAAGAACATTATCGCCGTGACGTCGGCAAAGGGTGGGGT
AGGTAAATCGACTACTTCTGTAAACCTTGCGCTTGCGTTATCTAAGTCAGGTTCAAAAGTGGGCTTGTTGGATGCGGATA
TCTACGGTCCATCTGTGCCTATGATGCTTGGTCAGCTAGACGCAAAACCAGAAGTACAGAATAACAAATGGATGATGCCA
ATCGAAGCTCACGGCATTTTTACTCATTCTATCGGTTACCTTGTATCAAAAGATGATGCAGCTATCTGGCGTGGTCCAAT
GGCGGCGAAAGCATTAGGTCAGCTTGTGAATGAAACCGTCTGGCCAGAGTTGGATTACCTTGTTATCGACATGCCACCGG
GTACGGGTGATATTCAGCTAACGCTTTCGCAGCAGATCCCAGTGACGGGCGCGGTTGTGGTGACCACCCCTCAAGATTTG
GCATTAGCCGATGCGCGTAAAGGTGTGGCGATGTTTGATAAAGTGAGCGTGCCAGTGGCAGGCTTAGTGGAAAACATGAG
CTACCATATCTGTAGCCACTGTGGCGAGAAAGAGCATATATTTGGCGCTGGTGGCGCGGAAGCCATGTCTGAAGAGTTTT
ACCTCGATATCTTAGCGCAAATCCCGCTGCACATTGATGTACGTGAAGATATTGATGCAGGTTGCCCAACCGTTATACGT
CGTCCAGATAGTGAACACACGCGTCATTACTTAGAGCTTGCTGAGAATGTGGCTGCGAAGATGTTCTGGACGGGAAAAGC
GAGACCAGAGGCGATTAACTTCTCGATGGTTGAATAG

Upstream 100 bases:

>100_bases
ACGTGTGATACGCCAAGTTATCAGACAAAGGATTCCCCTAGTTTTTTAGGGGTTCAGTCTTCATCTCGTGGGTGATAGCA
TAAATAAAAAAGGAGCCCCA

Downstream 100 bases:

>100_bases
CAATAGCTGATCACAAAGGTGTGTAAATCATGTTTGGGTGAGATAAACAACGGTTGGATTAAGTGGATAGCCATAGGGCT
TGTGCACATAGTTGTATTTA

Product: Mrp protein homolog

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 358; Mature: 358

Protein sequence:

>358_residues
MRNFTSKQDFCSWLNEFESPILIPEWALHQNIVSVDPRGSFVITLPFAANQLAIELEQWIHSQIEQQLVSAFQFEVKVKP
SALETTVATPLKGVKNIIAVTSAKGGVGKSTTSVNLALALSKSGSKVGLLDADIYGPSVPMMLGQLDAKPEVQNNKWMMP
IEAHGIFTHSIGYLVSKDDAAIWRGPMAAKALGQLVNETVWPELDYLVIDMPPGTGDIQLTLSQQIPVTGAVVVTTPQDL
ALADARKGVAMFDKVSVPVAGLVENMSYHICSHCGEKEHIFGAGGAEAMSEEFYLDILAQIPLHIDVREDIDAGCPTVIR
RPDSEHTRHYLELAENVAAKMFWTGKARPEAINFSMVE

Sequences:

>Translated_358_residues
MRNFTSKQDFCSWLNEFESPILIPEWALHQNIVSVDPRGSFVITLPFAANQLAIELEQWIHSQIEQQLVSAFQFEVKVKP
SALETTVATPLKGVKNIIAVTSAKGGVGKSTTSVNLALALSKSGSKVGLLDADIYGPSVPMMLGQLDAKPEVQNNKWMMP
IEAHGIFTHSIGYLVSKDDAAIWRGPMAAKALGQLVNETVWPELDYLVIDMPPGTGDIQLTLSQQIPVTGAVVVTTPQDL
ALADARKGVAMFDKVSVPVAGLVENMSYHICSHCGEKEHIFGAGGAEAMSEEFYLDILAQIPLHIDVREDIDAGCPTVIR
RPDSEHTRHYLELAENVAAKMFWTGKARPEAINFSMVE
>Mature_358_residues
MRNFTSKQDFCSWLNEFESPILIPEWALHQNIVSVDPRGSFVITLPFAANQLAIELEQWIHSQIEQQLVSAFQFEVKVKP
SALETTVATPLKGVKNIIAVTSAKGGVGKSTTSVNLALALSKSGSKVGLLDADIYGPSVPMMLGQLDAKPEVQNNKWMMP
IEAHGIFTHSIGYLVSKDDAAIWRGPMAAKALGQLVNETVWPELDYLVIDMPPGTGDIQLTLSQQIPVTGAVVVTTPQDL
ALADARKGVAMFDKVSVPVAGLVENMSYHICSHCGEKEHIFGAGGAEAMSEEFYLDILAQIPLHIDVREDIDAGCPTVIR
RPDSEHTRHYLELAENVAAKMFWTGKARPEAINFSMVE

Specific function: Not Known. [C]

COG id: COG0489

COG function: function code D; ATPases involved in chromosome partitioning

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Mrp/NBP35 ATP-binding proteins family [H]

Homologues:

Organism=Homo sapiens, GI157384956, Length=254, Percent_Identity=50.3937007874016, Blast_Score=259, Evalue=4e-69,
Organism=Homo sapiens, GI118572611, Length=254, Percent_Identity=37.4015748031496, Blast_Score=169, Evalue=4e-42,
Organism=Homo sapiens, GI6912540, Length=231, Percent_Identity=41.1255411255411, Blast_Score=168, Evalue=8e-42,
Organism=Escherichia coli, GI87082045, Length=267, Percent_Identity=63.2958801498127, Blast_Score=354, Evalue=6e-99,
Organism=Caenorhabditis elegans, GI25143050, Length=257, Percent_Identity=40.4669260700389, Blast_Score=174, Evalue=7e-44,
Organism=Saccharomyces cerevisiae, GI6322188, Length=225, Percent_Identity=38.6666666666667, Blast_Score=170, Evalue=3e-43,
Organism=Saccharomyces cerevisiae, GI6321347, Length=252, Percent_Identity=38.0952380952381, Blast_Score=160, Evalue=3e-40,
Organism=Drosophila melanogaster, GI221511043, Length=249, Percent_Identity=40.1606425702811, Blast_Score=209, Evalue=2e-54,
Organism=Drosophila melanogaster, GI24667611, Length=260, Percent_Identity=39.6153846153846, Blast_Score=177, Evalue=9e-45,
Organism=Drosophila melanogaster, GI19921440, Length=239, Percent_Identity=38.4937238493724, Blast_Score=138, Evalue=5e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR019591
- InterPro:   IPR000808 [H]

Pfam domain/function: PF10609 ParA [H]

EC number: NA

Molecular weight: Translated: 39091; Mature: 39091

Theoretical pI: Translated: 4.87; Mature: 4.87

Prosite motif: PS01215 MRP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRNFTSKQDFCSWLNEFESPILIPEWALHQNIVSVDPRGSFVITLPFAANQLAIELEQWI
CCCCCCHHHHHHHHHHHCCCEECCCHHHHCCEEEECCCCCEEEEECCCCCHHHHHHHHHH
HSQIEQQLVSAFQFEVKVKPSALETTVATPLKGVKNIIAVTSAKGGVGKSTTSVNLALAL
HHHHHHHHHHHHEEEEEECCCHHHHHHHHHHHHHHHEEEEECCCCCCCCCCCEEEEEEEE
SKSGSKVGLLDADIYGPSVPMMLGQLDAKPEVQNNKWMMPIEAHGIFTHSIGYLVSKDDA
ECCCCEEEEEECCCCCCCCHHHHHCCCCCCCCCCCCEEEEEECCCEEEECCCEEEECCCC
AIWRGPMAAKALGQLVNETVWPELDYLVIDMPPGTGDIQLTLSQQIPVTGAVVVTTPQDL
HHHCCCHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCEEEEEECCCCCEEEEEEECCCHH
ALADARKGVAMFDKVSVPVAGLVENMSYHICSHCGEKEHIFGAGGAEAMSEEFYLDILAQ
HHHHHHCCCEEEHHCCCCHHHHHHHHHHHHHHCCCCCCEEEECCCHHHHHHHHHHHHHHH
IPLHIDVREDIDAGCPTVIRRPDSEHTRHYLELAENVAAKMFWTGKARPEAINFSMVE
CCEEEEEHHCCCCCCCCEEECCCHHHHHHHHHHHHHHHHEEEECCCCCCCEECEEECC
>Mature Secondary Structure
MRNFTSKQDFCSWLNEFESPILIPEWALHQNIVSVDPRGSFVITLPFAANQLAIELEQWI
CCCCCCHHHHHHHHHHHCCCEECCCHHHHCCEEEECCCCCEEEEECCCCCHHHHHHHHHH
HSQIEQQLVSAFQFEVKVKPSALETTVATPLKGVKNIIAVTSAKGGVGKSTTSVNLALAL
HHHHHHHHHHHHEEEEEECCCHHHHHHHHHHHHHHHEEEEECCCCCCCCCCCEEEEEEEE
SKSGSKVGLLDADIYGPSVPMMLGQLDAKPEVQNNKWMMPIEAHGIFTHSIGYLVSKDDA
ECCCCEEEEEECCCCCCCCHHHHHCCCCCCCCCCCCEEEEEECCCEEEECCCEEEECCCC
AIWRGPMAAKALGQLVNETVWPELDYLVIDMPPGTGDIQLTLSQQIPVTGAVVVTTPQDL
HHHCCCHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCEEEEEECCCCCEEEEEEECCCHH
ALADARKGVAMFDKVSVPVAGLVENMSYHICSHCGEKEHIFGAGGAEAMSEEFYLDILAQ
HHHHHHCCCEEEHHCCCCHHHHHHHHHHHHHHCCCCCCEEEECCCHHHHHHHHHHHHHHH
IPLHIDVREDIDAGCPTVIRRPDSEHTRHYLELAENVAAKMFWTGKARPEAINFSMVE
CCEEEEEHHCCCCCCCCEEECCCHHHHHHHHHHHHHHHHEEEECCCCCCCEECEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]