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The map label for this gene is udk [H]

Identifier: 218709005

GI number: 218709005

Start: 1049614

End: 1050255

Strand: Direct

Name: udk [H]

Synonym: VS_1011

Alternate gene names: 218709005

Gene position: 1049614-1050255 (Clockwise)

Preceding gene: 218709004

Following gene: 218709006

Centisome position: 31.81

GC content: 43.3

Gene sequence:

>642_bases
ATGTCTGATAATAATCAATGTGTCATCGTAGGTATCGCTGGCGCTTCAGCTTCAGGAAAAAGCCTGATCGCGAGTACGAT
TTATAATGAGCTGCGCGAAAAAGTAGGCGACCATCAAATTGGTGTTATCACGGAAGATTGCTATTACAGCGACCAAAGTC
ACTTGAGTATGGAAGAGCGAGTTAAAACTAACTACGACCACCCAAATGCACTAGATCATGACCTTTTATGCGAACATCTA
CAGCAGCTAATGAGTGGCAATGCCGTGGAAGTTCCTGAATACAGCTACACAGAGCACACACGCACTTCTGAAACGACTAC
ACTTACTCCTAAGAAAGTGATCATTTTAGAAGGTATTCTGCTTCTGACAGACCCGCGTCTTCGTAAACTAATGCACGCAA
GCGTATTTATGGATACACCGTTGGACATCTGTCTACTACGTCGTGTTAAGCGTGATGTAGAAGAGCGTGGTCGAACAATG
GATACGGTACTTAAACAATACCAAGAAACAGTACGCCCAATGTTCATGCAGTTTATCGAGCCTTCAAAACAACATGCAGA
CATCATCGTTCCTCGTGGTGGTAAAAACCGTATTGCGATTGATGTGCTAAAAGCGCATATTGCGAAGTTGTTGAAGTCTT
AA

Upstream 100 bases:

>100_bases
CTGCAATTAGCTAACATCGCGACTAGAATCTATATGCTTTAGCCCCTATAATCAGGCGGTTTATCTCTTCCCACCACCAA
ACCATATCGGGTGCAAATTA

Downstream 100 bases:

>100_bases
TCGAATTAAATTTTGCCTAAGTGACTCACTTAGCTTTATTTTTTACCGAATCAGTGGCACTTTTATAGTGCCACTTTCTT
TTGGAATCTAAGCAAGGAAT

Product: uridine kinase

Products: NA

Alternate protein names: Cytidine monophosphokinase; Uridine monophosphokinase [H]

Number of amino acids: Translated: 213; Mature: 212

Protein sequence:

>213_residues
MSDNNQCVIVGIAGASASGKSLIASTIYNELREKVGDHQIGVITEDCYYSDQSHLSMEERVKTNYDHPNALDHDLLCEHL
QQLMSGNAVEVPEYSYTEHTRTSETTTLTPKKVIILEGILLLTDPRLRKLMHASVFMDTPLDICLLRRVKRDVEERGRTM
DTVLKQYQETVRPMFMQFIEPSKQHADIIVPRGGKNRIAIDVLKAHIAKLLKS

Sequences:

>Translated_213_residues
MSDNNQCVIVGIAGASASGKSLIASTIYNELREKVGDHQIGVITEDCYYSDQSHLSMEERVKTNYDHPNALDHDLLCEHL
QQLMSGNAVEVPEYSYTEHTRTSETTTLTPKKVIILEGILLLTDPRLRKLMHASVFMDTPLDICLLRRVKRDVEERGRTM
DTVLKQYQETVRPMFMQFIEPSKQHADIIVPRGGKNRIAIDVLKAHIAKLLKS
>Mature_212_residues
SDNNQCVIVGIAGASASGKSLIASTIYNELREKVGDHQIGVITEDCYYSDQSHLSMEERVKTNYDHPNALDHDLLCEHLQ
QLMSGNAVEVPEYSYTEHTRTSETTTLTPKKVIILEGILLLTDPRLRKLMHASVFMDTPLDICLLRRVKRDVEERGRTMD
TVLKQYQETVRPMFMQFIEPSKQHADIIVPRGGKNRIAIDVLKAHIAKLLKS

Specific function: Pyrimidine salvage pathway. [C]

COG id: COG0572

COG function: function code F; Uridine kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the uridine kinase family [H]

Homologues:

Organism=Homo sapiens, GI18699734, Length=217, Percent_Identity=35.0230414746544, Blast_Score=159, Evalue=1e-39,
Organism=Homo sapiens, GI301129207, Length=208, Percent_Identity=37.5, Blast_Score=157, Evalue=5e-39,
Organism=Homo sapiens, GI57863312, Length=208, Percent_Identity=37.5, Blast_Score=157, Evalue=5e-39,
Organism=Homo sapiens, GI13899253, Length=215, Percent_Identity=36.2790697674419, Blast_Score=153, Evalue=1e-37,
Organism=Homo sapiens, GI209863022, Length=153, Percent_Identity=33.3333333333333, Blast_Score=98, Evalue=5e-21,
Organism=Escherichia coli, GI87082034, Length=213, Percent_Identity=74.1784037558685, Blast_Score=339, Evalue=9e-95,
Organism=Caenorhabditis elegans, GI17539894, Length=205, Percent_Identity=37.5609756097561, Blast_Score=154, Evalue=4e-38,
Organism=Caenorhabditis elegans, GI17539892, Length=206, Percent_Identity=37.378640776699, Blast_Score=153, Evalue=5e-38,
Organism=Caenorhabditis elegans, GI71981181, Length=212, Percent_Identity=34.4339622641509, Blast_Score=134, Evalue=2e-32,
Organism=Saccharomyces cerevisiae, GI6324339, Length=177, Percent_Identity=31.638418079096, Blast_Score=111, Evalue=9e-26,
Organism=Drosophila melanogaster, GI24649624, Length=214, Percent_Identity=38.3177570093458, Blast_Score=167, Evalue=5e-42,
Organism=Drosophila melanogaster, GI221458995, Length=215, Percent_Identity=38.1395348837209, Blast_Score=166, Evalue=1e-41,
Organism=Drosophila melanogaster, GI28573516, Length=201, Percent_Identity=40.7960199004975, Blast_Score=162, Evalue=2e-40,
Organism=Drosophila melanogaster, GI28573514, Length=201, Percent_Identity=40.7960199004975, Blast_Score=162, Evalue=2e-40,
Organism=Drosophila melanogaster, GI28573512, Length=201, Percent_Identity=40.7960199004975, Blast_Score=162, Evalue=2e-40,
Organism=Drosophila melanogaster, GI45550449, Length=201, Percent_Identity=40.7960199004975, Blast_Score=162, Evalue=2e-40,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006083
- InterPro:   IPR000764 [H]

Pfam domain/function: PF00485 PRK [H]

EC number: =2.7.1.48 [H]

Molecular weight: Translated: 24147; Mature: 24016

Theoretical pI: Translated: 6.79; Mature: 6.79

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDNNQCVIVGIAGASASGKSLIASTIYNELREKVGDHQIGVITEDCYYSDQSHLSMEER
CCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCEEEEECCHHCCCCHHCCHHHH
VKTNYDHPNALDHDLLCEHLQQLMSGNAVEVPEYSYTEHTRTSETTTLTPKKVIILEGIL
HHCCCCCCCCCCHHHHHHHHHHHHCCCCEECCCCCCCCCCCCCCCEECCCCEEHHHHHHH
LLTDPRLRKLMHASVFMDTPLDICLLRRVKRDVEERGRTMDTVLKQYQETVRPMFMQFIE
HCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHC
PSKQHADIIVPRGGKNRIAIDVLKAHIAKLLKS
CCCCCCCEEEECCCCCCHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SDNNQCVIVGIAGASASGKSLIASTIYNELREKVGDHQIGVITEDCYYSDQSHLSMEER
CCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCEEEEECCHHCCCCHHCCHHHH
VKTNYDHPNALDHDLLCEHLQQLMSGNAVEVPEYSYTEHTRTSETTTLTPKKVIILEGIL
HHCCCCCCCCCCHHHHHHHHHHHHCCCCEECCCCCCCCCCCCCCCEECCCCEEHHHHHHH
LLTDPRLRKLMHASVFMDTPLDICLLRRVKRDVEERGRTMDTVLKQYQETVRPMFMQFIE
HCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHC
PSKQHADIIVPRGGKNRIAIDVLKAHIAKLLKS
CCCCCCCEEEECCCCCCHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10952301 [H]