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The map label for this gene is murG

Identifier: 218708486

GI number: 218708486

Start: 461128

End: 462189

Strand: Direct

Name: murG

Synonym: VS_0450

Alternate gene names: 218708486

Gene position: 461128-462189 (Clockwise)

Preceding gene: 218708485

Following gene: 218708487

Centisome position: 13.98

GC content: 46.61

Gene sequence:

>1062_bases
ATGAAACAAAACAAAAAACTTTTAGTGATGGCTGGTGGTACTGGCGGTCACGTTTTCCCAGGGTTAGCGGTGGCTAAAAA
GCTTCAGCAACAAGGTTGGGAAATTCGCTGGTTAGGAACCGCAGACAGAATGGAAGCAGATCTGGTGCCAAAACATGGTA
TTGAGATCGACTTCATTAAGGTGAAAGGCCTGCGTGGTCAAGGCGTTAGTAAATTAATTAAAGCGCCGTTCCAGATTATT
AATGCCATACTTCAAGCCAGACGACATATTAAAGCATGGCAACCTGATGTGGTGCTTGGCATGGGGGGGTACGTCAGTGG
CCCGGGTGGTATCGCGGCTTGGTTATCTGGCATTCCAGTGGTTCTACATGAACAAAATGCAGTGGCAGGTTTAACCAACC
AATGGCTGTCTAAGATTGCTAAAAAGGTTTTCCAAGCTTTTCCTGGTGCGTTTCCTACCGCAGAAGTGGTGGGTAACCCG
GTACGCGAAGATGTTGTTGCCTTAGCTGACCCCGAGCAACGCATGGCTGAGCGTGATGGTGACATCCGCATCTTGGTTAT
GGGCGGTAGCCAGGGCGCAAAAATCTTGAACGATACCTTGCCAGTAACGATGGCGCAGCTTGGTGAAGGCTTCACTGTGG
TGCATCAAGCGGGTAAGAACAATCAACAGCAAGTTATTGAACAATACAAATCACATTCTGTAGATAATGTTCAAGTGACT
GAATTTATTGATGATGTGGCGCAAGCTTATGAGTGGGCAGATCTATTAGTGTGTCGCTCTGGTGCATTAACCGTATCTGA
AGTGTCTGCTGCTGGTGTCGGTTCTATTTTCGTTCCGTTTATGCACAAAGACAGACAACAAGCGTTGAATGCCGATCATT
TAGTCGAATGTGGCGCAGCGTTAATGATTGAACAGCCTCAACTGACGGCTGATAAGCTCGCGAACACTATCGCGCAGCTT
GATAGAAATGAATTAAAAATGATGGCAACAAAAGCTCGTCAAGCCGCCAAGCTTGATGCTGATGTGACTGTCGCTGAAGC
GATTAAAGCTTTAGCAAAATAA

Upstream 100 bases:

>100_bases
AGCGGTTTCTATGCTGCTGCGTATCGATCATGAATGCCGAGTTCAACAAAAAGAACAAGCCGACAATCAAAACGAATTAG
TAGAATAAGAATCTAACGTT

Downstream 100 bases:

>100_bases
TGAGATTGAATTGATGACGATTGAACATACCCAAGACTTAGCGCAAATCCGTGCAATGGTGCCAGAGATGCGCCGTGTTA
AATCTATCCACTTCATTGGT

Product: undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase

Products: NA

Alternate protein names: Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase

Number of amino acids: Translated: 353; Mature: 353

Protein sequence:

>353_residues
MKQNKKLLVMAGGTGGHVFPGLAVAKKLQQQGWEIRWLGTADRMEADLVPKHGIEIDFIKVKGLRGQGVSKLIKAPFQII
NAILQARRHIKAWQPDVVLGMGGYVSGPGGIAAWLSGIPVVLHEQNAVAGLTNQWLSKIAKKVFQAFPGAFPTAEVVGNP
VREDVVALADPEQRMAERDGDIRILVMGGSQGAKILNDTLPVTMAQLGEGFTVVHQAGKNNQQQVIEQYKSHSVDNVQVT
EFIDDVAQAYEWADLLVCRSGALTVSEVSAAGVGSIFVPFMHKDRQQALNADHLVECGAALMIEQPQLTADKLANTIAQL
DRNELKMMATKARQAAKLDADVTVAEAIKALAK

Sequences:

>Translated_353_residues
MKQNKKLLVMAGGTGGHVFPGLAVAKKLQQQGWEIRWLGTADRMEADLVPKHGIEIDFIKVKGLRGQGVSKLIKAPFQII
NAILQARRHIKAWQPDVVLGMGGYVSGPGGIAAWLSGIPVVLHEQNAVAGLTNQWLSKIAKKVFQAFPGAFPTAEVVGNP
VREDVVALADPEQRMAERDGDIRILVMGGSQGAKILNDTLPVTMAQLGEGFTVVHQAGKNNQQQVIEQYKSHSVDNVQVT
EFIDDVAQAYEWADLLVCRSGALTVSEVSAAGVGSIFVPFMHKDRQQALNADHLVECGAALMIEQPQLTADKLANTIAQL
DRNELKMMATKARQAAKLDADVTVAEAIKALAK
>Mature_353_residues
MKQNKKLLVMAGGTGGHVFPGLAVAKKLQQQGWEIRWLGTADRMEADLVPKHGIEIDFIKVKGLRGQGVSKLIKAPFQII
NAILQARRHIKAWQPDVVLGMGGYVSGPGGIAAWLSGIPVVLHEQNAVAGLTNQWLSKIAKKVFQAFPGAFPTAEVVGNP
VREDVVALADPEQRMAERDGDIRILVMGGSQGAKILNDTLPVTMAQLGEGFTVVHQAGKNNQQQVIEQYKSHSVDNVQVT
EFIDDVAQAYEWADLLVCRSGALTVSEVSAAGVGSIFVPFMHKDRQQALNADHLVECGAALMIEQPQLTADKLANTIAQL
DRNELKMMATKARQAAKLDADVTVAEAIKALAK

Specific function: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)

COG id: COG0707

COG function: function code M; UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 28 family. MurG subfamily

Homologues:

Organism=Escherichia coli, GI1786278, Length=351, Percent_Identity=64.1025641025641, Blast_Score=462, Evalue=1e-131,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MURG_VIBSL (B7VJ03)

Other databases:

- EMBL:   FM954972
- RefSeq:   YP_002416107.1
- ProteinModelPortal:   B7VJ03
- GeneID:   7160085
- GenomeReviews:   FM954972_GR
- KEGG:   vsp:VS_0450
- HOGENOM:   HBG617076
- OMA:   IGFGGYP
- ProtClustDB:   PRK00726
- HAMAP:   MF_00033
- InterPro:   IPR006009
- InterPro:   IPR004276
- InterPro:   IPR007235
- TIGRFAMs:   TIGR01133

Pfam domain/function: PF04101 Glyco_tran_28_C; PF03033 Glyco_transf_28

EC number: =2.4.1.227

Molecular weight: Translated: 38074; Mature: 38074

Theoretical pI: Translated: 8.25; Mature: 8.25

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKQNKKLLVMAGGTGGHVFPGLAVAKKLQQQGWEIRWLGTADRMEADLVPKHGIEIDFIK
CCCCCEEEEEECCCCCCCCHHHHHHHHHHHCCCEEEEECCHHHHCCCCCCCCCCEEEEEE
VKGLRGQGVSKLIKAPFQIINAILQARRHIKAWQPDVVLGMGGYVSGPGGIAAWLSGIPV
EECCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCHHHHHHCCCCE
VLHEQNAVAGLTNQWLSKIAKKVFQAFPGAFPTAEVVGNPVREDVVALADPEQRMAERDG
EEECCCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHCCCHHHHHHHHCCCHHHHHHCCC
DIRILVMGGSQGAKILNDTLPVTMAQLGEGFTVVHQAGKNNQQQVIEQYKSHSVDNVQVT
CEEEEEEECCCCCHHHHCCCCHHHHHHCCCEEEEECCCCCCHHHHHHHHHHCCCCCCHHH
EFIDDVAQAYEWADLLVCRSGALTVSEVSAAGVGSIFVPFMHKDRQQALNADHLVECGAA
HHHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCCHHHHHHHHCCHHHHCCHHHHHHCCHH
LMIEQPQLTADKLANTIAQLDRNELKMMATKARQAAKLDADVTVAEAIKALAK
EEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCC
>Mature Secondary Structure
MKQNKKLLVMAGGTGGHVFPGLAVAKKLQQQGWEIRWLGTADRMEADLVPKHGIEIDFIK
CCCCCEEEEEECCCCCCCCHHHHHHHHHHHCCCEEEEECCHHHHCCCCCCCCCCEEEEEE
VKGLRGQGVSKLIKAPFQIINAILQARRHIKAWQPDVVLGMGGYVSGPGGIAAWLSGIPV
EECCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCHHHHHHCCCCE
VLHEQNAVAGLTNQWLSKIAKKVFQAFPGAFPTAEVVGNPVREDVVALADPEQRMAERDG
EEECCCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHCCCHHHHHHHHCCCHHHHHHCCC
DIRILVMGGSQGAKILNDTLPVTMAQLGEGFTVVHQAGKNNQQQVIEQYKSHSVDNVQVT
CEEEEEEECCCCCHHHHCCCCHHHHHHCCCEEEEECCCCCCHHHHHHHHHHCCCCCCHHH
EFIDDVAQAYEWADLLVCRSGALTVSEVSAAGVGSIFVPFMHKDRQQALNADHLVECGAA
HHHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCCHHHHHHHHCCHHHHCCHHHHHHCCHH
LMIEQPQLTADKLANTIAQLDRNELKMMATKARQAAKLDADVTVAEAIKALAK
EEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA