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The map label for this gene is ftsW [H]

Identifier: 218708485

GI number: 218708485

Start: 459919

End: 461115

Strand: Direct

Name: ftsW [H]

Synonym: VS_0449

Alternate gene names: 218708485

Gene position: 459919-461115 (Clockwise)

Preceding gene: 218708484

Following gene: 218708486

Centisome position: 13.94

GC content: 45.28

Gene sequence:

>1197_bases
GTGCAAAGAGTGAAAGAGATTAATCAATCTATTTGGCAATGGCTTAACCGTGCCACACCAGAGGCGCTCTACGATCGTCA
GTTGGTATGGATTGCTCTTGGACTGATGCTGACGGGCTTGGTGATGGTAACGTCGGCTTCGTTCCCAATCAGTGCTCGTT
TAACCGATCAGCCGTTTCACTTCATGTTCCGCCACGCCATTTTCCTGGTGTTAGCGTTAGGTGTATCCAGCGTAATATTA
CAAATCCCGATGAAACGCTGGTTTCAATACAGTATGTACCTATTGGGCTTATCCTTCTTTTTGCTAGTGGTGGTGTTAGC
CGTCGGTAAGTCGGTTAACGGTGCCTCACGTTGGATTCCTCTCGGGCTGTTTAACTTACAACCTGCTGAAGTCGCTAAGT
TATCTCTGTTTATCTTTATGGCGGGCTATTTGGTTCGTAAACAGGATGAAGTGAGAAAAACCTTCTTCGGTGGTTTTGGT
AAACCGATCATGGTGTTCGGTGCCTTTGCGGTGTTGCTACTTGGCCAGCCCGATTTGGGTACCGTTGTCGTAATGTTGGT
TACCTTGTTTGGCATGTTATTTATCGCAGGTGCTAAGCTGTCACAATTTATAGCCTTAATGGTGGCAGGTATTGCTGCCG
TTGTGGGATTGATTGTTATTGAGCCTTATCGTGTTCGACGTGTTACGTCATTCTGGGAACCTTGGAGTGACCCGTTTGGT
AGTGGTTATCAGCTAACTCAATCATTGATGGCGTTCGGTCGTGGTGATTGGATGGGGCAAGGGCTTGGTAATTCAATTCA
AAAACTCGAGTACCTACCTGAAGCACACACCGATTTTGTTTTTGCTGTACTGGCTGAAGAGTTGGGTTTTGTTGGCGTAA
CCTTAGTGTTGATGCTGATCTTTAGTTTGGTTTTTAAAGCTATTTTTATTGGCAAAAAAGCTTTCGAAAACGACCAAGTG
TTCAGCGGTTATCTGGCGTTTGGCATTGGTATTTGGTTTGCTTTTCAGACGCTTGTTAATGTAGGTGCCGCTTCAGGTAT
TGTTCCGACCAAGGGGCTAACCTTACCGCTGATCAGTTACGGTGGTTCAAGCCTTATCGTGATGTCAGTAGCGGTTTCTA
TGCTGCTGCGTATCGATCATGAATGCCGAGTTCAACAAAAAGAACAAGCCGACAATCAAAACGAATTAGTAGAATAA

Upstream 100 bases:

>100_bases
TGTGCAAGCTTCGATCAATTTAATAACTTCATGGCGAGAGGTGATGCGTTCACTGAACTTGCTCATGAGTATGCCTAACG
TGTTGAAGGACTAACATTCA

Downstream 100 bases:

>100_bases
GAATCTAACGTTATGAAACAAAACAAAAAACTTTTAGTGATGGCTGGTGGTACTGGCGGTCACGTTTTCCCAGGGTTAGC
GGTGGCTAAAAAGCTTCAGC

Product: cell division protein FtxW

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 398; Mature: 398

Protein sequence:

>398_residues
MQRVKEINQSIWQWLNRATPEALYDRQLVWIALGLMLTGLVMVTSASFPISARLTDQPFHFMFRHAIFLVLALGVSSVIL
QIPMKRWFQYSMYLLGLSFFLLVVVLAVGKSVNGASRWIPLGLFNLQPAEVAKLSLFIFMAGYLVRKQDEVRKTFFGGFG
KPIMVFGAFAVLLLGQPDLGTVVVMLVTLFGMLFIAGAKLSQFIALMVAGIAAVVGLIVIEPYRVRRVTSFWEPWSDPFG
SGYQLTQSLMAFGRGDWMGQGLGNSIQKLEYLPEAHTDFVFAVLAEELGFVGVTLVLMLIFSLVFKAIFIGKKAFENDQV
FSGYLAFGIGIWFAFQTLVNVGAASGIVPTKGLTLPLISYGGSSLIVMSVAVSMLLRIDHECRVQQKEQADNQNELVE

Sequences:

>Translated_398_residues
MQRVKEINQSIWQWLNRATPEALYDRQLVWIALGLMLTGLVMVTSASFPISARLTDQPFHFMFRHAIFLVLALGVSSVIL
QIPMKRWFQYSMYLLGLSFFLLVVVLAVGKSVNGASRWIPLGLFNLQPAEVAKLSLFIFMAGYLVRKQDEVRKTFFGGFG
KPIMVFGAFAVLLLGQPDLGTVVVMLVTLFGMLFIAGAKLSQFIALMVAGIAAVVGLIVIEPYRVRRVTSFWEPWSDPFG
SGYQLTQSLMAFGRGDWMGQGLGNSIQKLEYLPEAHTDFVFAVLAEELGFVGVTLVLMLIFSLVFKAIFIGKKAFENDQV
FSGYLAFGIGIWFAFQTLVNVGAASGIVPTKGLTLPLISYGGSSLIVMSVAVSMLLRIDHECRVQQKEQADNQNELVE
>Mature_398_residues
MQRVKEINQSIWQWLNRATPEALYDRQLVWIALGLMLTGLVMVTSASFPISARLTDQPFHFMFRHAIFLVLALGVSSVIL
QIPMKRWFQYSMYLLGLSFFLLVVVLAVGKSVNGASRWIPLGLFNLQPAEVAKLSLFIFMAGYLVRKQDEVRKTFFGGFG
KPIMVFGAFAVLLLGQPDLGTVVVMLVTLFGMLFIAGAKLSQFIALMVAGIAAVVGLIVIEPYRVRRVTSFWEPWSDPFG
SGYQLTQSLMAFGRGDWMGQGLGNSIQKLEYLPEAHTDFVFAVLAEELGFVGVTLVLMLIFSLVFKAIFIGKKAFENDQV
FSGYLAFGIGIWFAFQTLVNVGAASGIVPTKGLTLPLISYGGSSLIVMSVAVSMLLRIDHECRVQQKEQADNQNELVE

Specific function: This is a septum-peptidoglycan biosynthetic protein, involved in cell wall formation. Plays a role in the stabilization of the ftsZ ring during cell division [H]

COG id: COG0772

COG function: function code D; Bacterial cell division membrane protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsW/rodA/spoVE family [H]

Homologues:

Organism=Escherichia coli, GI1786277, Length=366, Percent_Identity=62.568306010929, Blast_Score=451, Evalue=1e-128,
Organism=Escherichia coli, GI1786853, Length=337, Percent_Identity=32.9376854599407, Blast_Score=154, Evalue=1e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001182
- InterPro:   IPR018365
- InterPro:   IPR013437 [H]

Pfam domain/function: PF01098 FTSW_RODA_SPOVE [H]

EC number: NA

Molecular weight: Translated: 44097; Mature: 44097

Theoretical pI: Translated: 9.44; Mature: 9.44

Prosite motif: PS00428 FTSW_RODA_SPOVE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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CCCHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure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CCCHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]