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The map label for this gene is ydiD [C]

Identifier: 218708425

GI number: 218708425

Start: 390306

End: 392114

Strand: Direct

Name: ydiD [C]

Synonym: VS_0387

Alternate gene names: 218708425

Gene position: 390306-392114 (Clockwise)

Preceding gene: 218708424

Following gene: 218708426

Centisome position: 11.83

GC content: 44.22

Gene sequence:

>1809_bases
ATGGCCAATTTAGATTTTCATATCGTAAAAAGACTTCGTGACCAAATTGCCCAAGGTGGCAACCGTACAGCTTTGAAGCA
CAAAGTAGGCAATGTATGGCAAGGTATTAGCTGGGAACAATTTGGACAACAAATCGATACGCTTTCATTAGCGCTATTGG
CTCAAGGATTGAGAGTTCAGGATAAGATCGGTATCTTCTCGAACAATATGCCTCAGTGGACTGTGGCTGACTTCGCATCC
TTACAAGCGCGTCTTGTAACGGTACCAATCTACCCAACCAACACAGCGGCGCAGTCTTCTTACATTATCCAAAATGCAGA
TGTGAAGATCTTATTCGTTGGCGAGCAAGCTCAGTTCGATGCGGCGGTTAGCCTTTTTGAAGAGTGTGAACAGCTAGAAG
TTGTTGTGGCGATGTCTGATGATATCGATCTGCAAGGACATCGCTTTGCCGTCTCTTGGAAAGAATTCATGGCTCGTGGT
GTTGAAGATCAGCAAGCTGAACTTGATGTTCGTCTTGCGGATGCCTGCATGGATGACTTACTGACGCTTATCTATACCTC
TGGTACAACGGGCCAGCCTAAAGGTGTAATGCTTGATTACACTAATGTTGGCTATCAACTAAAAGGCCATGATGAGCGTC
TCAGCTTAAGCAAAGACGACGTCTCATTGTGTTTCTTACCTCTATCACATGTATTTGAGCGCGCTTGGACTTTCTATGTC
CTTTATAAAGGCGCAACCAACTGCTATCTGCAAGACACCATGCAAGTTCGTGATGCATTGAGTGATGTTAAACCAACGGT
TATGTCTGCTGTTCCTCGCTTTTACGAGAAGATTTTCTCAGCGATTCACGAGAAAGTATCGAAAGCACCGTTTATTCGTA
AAGTACTCTTTACTTGGGCGGTGAACATGGGCGCGAAGCTTTCTGTTTGTCATCAAGAAGGTCGTACACCATCATTCATG
CTGAAGAAGAGCCATGCGCTTGCTGACAAGCTTGTGCTCTCAAAACTGCGAGCTCTGTTAGGTGGTAACATCAACTTCAT
GCCATGTGGTGGCGCGAAGCTTGATGAAACCATTGGTCGCTTCTTCCACGCGATTGGTATCAATGTAAAACTTGGCTACG
GCATGACAGAAACCACGGCAACAGTATCGTGCTGGGATGACCGTTGTTTTAACCCTGATTCGATCGGTATGTCGATGCCG
GGCGCTGAAGTGAAAATTGGCGCTAAGGACGAGATTCTTGTTCGTGGCCCAATGGTGATGCGTGGCTACTACAAGATGCC
AGAAGAGACAGCTAAAACATTTGACGAGCATGGTTTCCTAAAAACGGGTGATGCAGGTCATTTTGATGAAAATGGTAATC
TATTCATTACTGATCGCATCAAAGAATTAATGAAGACTTCTGGCGGTAAGTACATTGCACCGCAAGTGGTTGAAGGCGCA
ATTGGTAAAGATCACTTTATCGAGCAGATTGCTGTTATCGCTGATACGCGCAAATTCGTTTCTGCACTGATTGTTCCTTG
TTATGACTCGCTAGAAGAGTATGCCAAAGAGCTTAATATCAAATATCATGACCGTGTAGAACTTGTGAAAAATCACCAAA
TAGTAGAAATGCTAGAGAAGCGTGTGAATGACTTACAACAAGAGCTAGCGAAGTTTGAGCAAGTGAAGAAGTTCAAGTTG
CTGCCAAAAGCGTTTTCTATGGATGATGGTGAGCTAACACCGACCCAGAAACTGCGTCGTAAGGTTATTAACGATAAGTA
TCAAGACGAAATCGAAGAAATGTACAACGAAAAGCCTAAAGATAAGTAG

Upstream 100 bases:

>100_bases
TATTACTTATAACTTTGAGCTTCATCAGTTGCCTTTTCCATGATCAGAGGTACACTTGTGCGCTCAAAAAAGCTTACAGG
TGTAAGCCAAAGGTAAAGAG

Downstream 100 bases:

>100_bases
TTTTCTGTTTAGATAAATTTTCAGTTGTTTAAAAATCCCCCTACGAATGTGATTGCATTTTTAGGGGGATTTTTTGTATC
TAATGACACAGCACAATGTG

Product: long-chain-fatty-acid--CoA ligase

Products: NA

Alternate protein names: Long-chain acyl-CoA synthetase; LACS [H]

Number of amino acids: Translated: 602; Mature: 601

Protein sequence:

>602_residues
MANLDFHIVKRLRDQIAQGGNRTALKHKVGNVWQGISWEQFGQQIDTLSLALLAQGLRVQDKIGIFSNNMPQWTVADFAS
LQARLVTVPIYPTNTAAQSSYIIQNADVKILFVGEQAQFDAAVSLFEECEQLEVVVAMSDDIDLQGHRFAVSWKEFMARG
VEDQQAELDVRLADACMDDLLTLIYTSGTTGQPKGVMLDYTNVGYQLKGHDERLSLSKDDVSLCFLPLSHVFERAWTFYV
LYKGATNCYLQDTMQVRDALSDVKPTVMSAVPRFYEKIFSAIHEKVSKAPFIRKVLFTWAVNMGAKLSVCHQEGRTPSFM
LKKSHALADKLVLSKLRALLGGNINFMPCGGAKLDETIGRFFHAIGINVKLGYGMTETTATVSCWDDRCFNPDSIGMSMP
GAEVKIGAKDEILVRGPMVMRGYYKMPEETAKTFDEHGFLKTGDAGHFDENGNLFITDRIKELMKTSGGKYIAPQVVEGA
IGKDHFIEQIAVIADTRKFVSALIVPCYDSLEEYAKELNIKYHDRVELVKNHQIVEMLEKRVNDLQQELAKFEQVKKFKL
LPKAFSMDDGELTPTQKLRRKVINDKYQDEIEEMYNEKPKDK

Sequences:

>Translated_602_residues
MANLDFHIVKRLRDQIAQGGNRTALKHKVGNVWQGISWEQFGQQIDTLSLALLAQGLRVQDKIGIFSNNMPQWTVADFAS
LQARLVTVPIYPTNTAAQSSYIIQNADVKILFVGEQAQFDAAVSLFEECEQLEVVVAMSDDIDLQGHRFAVSWKEFMARG
VEDQQAELDVRLADACMDDLLTLIYTSGTTGQPKGVMLDYTNVGYQLKGHDERLSLSKDDVSLCFLPLSHVFERAWTFYV
LYKGATNCYLQDTMQVRDALSDVKPTVMSAVPRFYEKIFSAIHEKVSKAPFIRKVLFTWAVNMGAKLSVCHQEGRTPSFM
LKKSHALADKLVLSKLRALLGGNINFMPCGGAKLDETIGRFFHAIGINVKLGYGMTETTATVSCWDDRCFNPDSIGMSMP
GAEVKIGAKDEILVRGPMVMRGYYKMPEETAKTFDEHGFLKTGDAGHFDENGNLFITDRIKELMKTSGGKYIAPQVVEGA
IGKDHFIEQIAVIADTRKFVSALIVPCYDSLEEYAKELNIKYHDRVELVKNHQIVEMLEKRVNDLQQELAKFEQVKKFKL
LPKAFSMDDGELTPTQKLRRKVINDKYQDEIEEMYNEKPKDK
>Mature_601_residues
ANLDFHIVKRLRDQIAQGGNRTALKHKVGNVWQGISWEQFGQQIDTLSLALLAQGLRVQDKIGIFSNNMPQWTVADFASL
QARLVTVPIYPTNTAAQSSYIIQNADVKILFVGEQAQFDAAVSLFEECEQLEVVVAMSDDIDLQGHRFAVSWKEFMARGV
EDQQAELDVRLADACMDDLLTLIYTSGTTGQPKGVMLDYTNVGYQLKGHDERLSLSKDDVSLCFLPLSHVFERAWTFYVL
YKGATNCYLQDTMQVRDALSDVKPTVMSAVPRFYEKIFSAIHEKVSKAPFIRKVLFTWAVNMGAKLSVCHQEGRTPSFML
KKSHALADKLVLSKLRALLGGNINFMPCGGAKLDETIGRFFHAIGINVKLGYGMTETTATVSCWDDRCFNPDSIGMSMPG
AEVKIGAKDEILVRGPMVMRGYYKMPEETAKTFDEHGFLKTGDAGHFDENGNLFITDRIKELMKTSGGKYIAPQVVEGAI
GKDHFIEQIAVIADTRKFVSALIVPCYDSLEEYAKELNIKYHDRVELVKNHQIVEMLEKRVNDLQQELAKFEQVKKFKLL
PKAFSMDDGELTPTQKLRRKVINDKYQDEIEEMYNEKPKDK

Specific function: Unknown

COG id: COG1022

COG function: function code I; Long-chain acyl-CoA synthetases (AMP-forming)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATP-dependent AMP-binding enzyme family [H]

Homologues:

Organism=Homo sapiens, GI27477105, Length=639, Percent_Identity=29.1079812206573, Blast_Score=241, Evalue=1e-63,
Organism=Homo sapiens, GI40807491, Length=594, Percent_Identity=28.2828282828283, Blast_Score=234, Evalue=2e-61,
Organism=Homo sapiens, GI57165412, Length=617, Percent_Identity=28.8492706645057, Blast_Score=229, Evalue=7e-60,
Organism=Homo sapiens, GI57165410, Length=620, Percent_Identity=28.3870967741935, Blast_Score=226, Evalue=6e-59,
Organism=Homo sapiens, GI83745141, Length=619, Percent_Identity=27.7867528271405, Blast_Score=224, Evalue=1e-58,
Organism=Homo sapiens, GI42794756, Length=608, Percent_Identity=27.7960526315789, Blast_Score=224, Evalue=2e-58,
Organism=Homo sapiens, GI42794760, Length=608, Percent_Identity=27.7960526315789, Blast_Score=224, Evalue=2e-58,
Organism=Homo sapiens, GI42794758, Length=608, Percent_Identity=27.7960526315789, Blast_Score=224, Evalue=2e-58,
Organism=Homo sapiens, GI42794754, Length=592, Percent_Identity=28.8851351351351, Blast_Score=200, Evalue=4e-51,
Organism=Homo sapiens, GI42794752, Length=592, Percent_Identity=28.8851351351351, Blast_Score=200, Evalue=4e-51,
Organism=Homo sapiens, GI12669909, Length=616, Percent_Identity=25, Blast_Score=177, Evalue=4e-44,
Organism=Homo sapiens, GI4758332, Length=616, Percent_Identity=25, Blast_Score=176, Evalue=4e-44,
Organism=Escherichia coli, GI145693145, Length=463, Percent_Identity=25.7019438444924, Blast_Score=97, Evalue=3e-21,
Organism=Escherichia coli, GI221142682, Length=482, Percent_Identity=21.1618257261411, Blast_Score=89, Evalue=8e-19,
Organism=Escherichia coli, GI1788107, Length=481, Percent_Identity=21.6216216216216, Blast_Score=80, Evalue=5e-16,
Organism=Escherichia coli, GI1786810, Length=452, Percent_Identity=21.4601769911504, Blast_Score=71, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17556552, Length=601, Percent_Identity=28.9517470881864, Blast_Score=239, Evalue=3e-63,
Organism=Caenorhabditis elegans, GI17541856, Length=594, Percent_Identity=30.6397306397306, Blast_Score=220, Evalue=2e-57,
Organism=Caenorhabditis elegans, GI17510401, Length=603, Percent_Identity=28.8557213930348, Blast_Score=209, Evalue=4e-54,
Organism=Caenorhabditis elegans, GI193204819, Length=630, Percent_Identity=28.0952380952381, Blast_Score=197, Evalue=2e-50,
Organism=Caenorhabditis elegans, GI17553312, Length=623, Percent_Identity=26.4847512038523, Blast_Score=195, Evalue=6e-50,
Organism=Caenorhabditis elegans, GI17564090, Length=546, Percent_Identity=27.6556776556777, Blast_Score=186, Evalue=2e-47,
Organism=Caenorhabditis elegans, GI25147511, Length=596, Percent_Identity=25.6711409395973, Blast_Score=184, Evalue=1e-46,
Organism=Caenorhabditis elegans, GI17531443, Length=469, Percent_Identity=24.7334754797441, Blast_Score=118, Evalue=1e-26,
Organism=Caenorhabditis elegans, GI17559526, Length=372, Percent_Identity=28.2258064516129, Blast_Score=108, Evalue=8e-24,
Organism=Caenorhabditis elegans, GI17558820, Length=385, Percent_Identity=24.6753246753247, Blast_Score=97, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI32563687, Length=525, Percent_Identity=22.8571428571429, Blast_Score=92, Evalue=8e-19,
Organism=Caenorhabditis elegans, GI133901848, Length=216, Percent_Identity=28.2407407407407, Blast_Score=82, Evalue=7e-16,
Organism=Caenorhabditis elegans, GI71985884, Length=335, Percent_Identity=25.9701492537313, Blast_Score=80, Evalue=3e-15,
Organism=Saccharomyces cerevisiae, GI6324893, Length=447, Percent_Identity=29.3064876957494, Blast_Score=176, Evalue=1e-44,
Organism=Saccharomyces cerevisiae, GI6320852, Length=575, Percent_Identity=26.0869565217391, Blast_Score=169, Evalue=2e-42,
Organism=Saccharomyces cerevisiae, GI6322182, Length=468, Percent_Identity=27.991452991453, Blast_Score=159, Evalue=2e-39,
Organism=Saccharomyces cerevisiae, GI6323903, Length=584, Percent_Identity=24.8287671232877, Blast_Score=153, Evalue=8e-38,
Organism=Drosophila melanogaster, GI281366413, Length=589, Percent_Identity=31.918505942275, Blast_Score=248, Evalue=1e-65,
Organism=Drosophila melanogaster, GI24666501, Length=589, Percent_Identity=31.918505942275, Blast_Score=247, Evalue=2e-65,
Organism=Drosophila melanogaster, GI24666497, Length=589, Percent_Identity=31.918505942275, Blast_Score=247, Evalue=2e-65,
Organism=Drosophila melanogaster, GI17933690, Length=621, Percent_Identity=26.0869565217391, Blast_Score=234, Evalue=2e-61,
Organism=Drosophila melanogaster, GI19921316, Length=624, Percent_Identity=27.5641025641026, Blast_Score=218, Evalue=1e-56,
Organism=Drosophila melanogaster, GI62471679, Length=620, Percent_Identity=27.258064516129, Blast_Score=189, Evalue=6e-48,
Organism=Drosophila melanogaster, GI62471683, Length=620, Percent_Identity=27.258064516129, Blast_Score=189, Evalue=6e-48,
Organism=Drosophila melanogaster, GI62471685, Length=620, Percent_Identity=27.258064516129, Blast_Score=189, Evalue=6e-48,
Organism=Drosophila melanogaster, GI24586636, Length=620, Percent_Identity=27.258064516129, Blast_Score=189, Evalue=6e-48,
Organism=Drosophila melanogaster, GI62471689, Length=620, Percent_Identity=27.258064516129, Blast_Score=188, Evalue=7e-48,
Organism=Drosophila melanogaster, GI62471681, Length=620, Percent_Identity=27.258064516129, Blast_Score=188, Evalue=9e-48,
Organism=Drosophila melanogaster, GI62471687, Length=620, Percent_Identity=27.258064516129, Blast_Score=188, Evalue=9e-48,
Organism=Drosophila melanogaster, GI24586634, Length=620, Percent_Identity=27.258064516129, Blast_Score=188, Evalue=9e-48,
Organism=Drosophila melanogaster, GI22026970, Length=620, Percent_Identity=27.258064516129, Blast_Score=188, Evalue=9e-48,
Organism=Drosophila melanogaster, GI21355181, Length=498, Percent_Identity=26.1044176706827, Blast_Score=110, Evalue=2e-24,
Organism=Drosophila melanogaster, GI18859661, Length=450, Percent_Identity=24.2222222222222, Blast_Score=91, Evalue=3e-18,
Organism=Drosophila melanogaster, GI24653035, Length=189, Percent_Identity=31.7460317460317, Blast_Score=71, Evalue=2e-12,
Organism=Drosophila melanogaster, GI21356947, Length=220, Percent_Identity=27.2727272727273, Blast_Score=70, Evalue=5e-12,
Organism=Drosophila melanogaster, GI161076582, Length=189, Percent_Identity=31.2169312169312, Blast_Score=70, Evalue=5e-12,
Organism=Drosophila melanogaster, GI24648260, Length=223, Percent_Identity=28.2511210762332, Blast_Score=69, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020845
- InterPro:   IPR000873 [H]

Pfam domain/function: PF00501 AMP-binding [H]

EC number: =6.2.1.3 [H]

Molecular weight: Translated: 67902; Mature: 67771

Theoretical pI: Translated: 6.40; Mature: 6.40

Prosite motif: PS00455 AMP_BINDING

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MANLDFHIVKRLRDQIAQGGNRTALKHKVGNVWQGISWEQFGQQIDTLSLALLAQGLRVQ
CCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCH
DKIGIFSNNMPQWTVADFASLQARLVTVPIYPTNTAAQSSYIIQNADVKILFVGEQAQFD
HHCCCCCCCCCCCHHHHHHCCCEEEEEEEEECCCCCCCCCEEEECCCEEEEEECCCHHHH
AAVSLFEECEQLEVVVAMSDDIDLQGHRFAVSWKEFMARGVEDQQAELDVRLADACMDDL
HHHHHHHHHHHEEEEEEECCCCCCCCCEEEEEHHHHHHCCCCCHHHHHHHHHHHHHHHHH
LTLIYTSGTTGQPKGVMLDYTNVGYQLKGHDERLSLSKDDVSLCFLPLSHVFERAWTFYV
HHHHHCCCCCCCCCCEEEEECCCCEEECCCCCCCCCCCCCCCEEEHHHHHHHHHHHEEEE
LYKGATNCYLQDTMQVRDALSDVKPTVMSAVPRFYEKIFSAIHEKVSKAPFIRKVLFTWA
EEECCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHH
VNMGAKLSVCHQEGRTPSFMLKKSHALADKLVLSKLRALLGGNINFMPCGGAKLDETIGR
HCCCCEEEEHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCHHHHHHHH
FFHAIGINVKLGYGMTETTATVSCWDDRCFNPDSIGMSMPGAEVKIGAKDEILVRGPMVM
HHHHHCCEEEECCCCCCCCEEEEECCCCCCCCCCCCCCCCCCEEEECCCCCEEEECCHHH
RGYYKMPEETAKTFDEHGFLKTGDAGHFDENGNLFITDRIKELMKTSGGKYIAPQVVEGA
HHHHCCCHHHHHHHHHCCCEECCCCCCCCCCCCEEEHHHHHHHHHCCCCCEECHHHHHCC
IGKDHFIEQIAVIADTRKFVSALIVPCYDSLEEYAKELNIKYHDRVELVKNHQIVEMLEK
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCHHHHHHHHH
RVNDLQQELAKFEQVKKFKLLPKAFSMDDGELTPTQKLRRKVINDKYQDEIEEMYNEKPK
HHHHHHHHHHHHHHHHHHHHCCHHCCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHCCCCC
DK
CC
>Mature Secondary Structure 
ANLDFHIVKRLRDQIAQGGNRTALKHKVGNVWQGISWEQFGQQIDTLSLALLAQGLRVQ
CCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCH
DKIGIFSNNMPQWTVADFASLQARLVTVPIYPTNTAAQSSYIIQNADVKILFVGEQAQFD
HHCCCCCCCCCCCHHHHHHCCCEEEEEEEEECCCCCCCCCEEEECCCEEEEEECCCHHHH
AAVSLFEECEQLEVVVAMSDDIDLQGHRFAVSWKEFMARGVEDQQAELDVRLADACMDDL
HHHHHHHHHHHEEEEEEECCCCCCCCCEEEEEHHHHHHCCCCCHHHHHHHHHHHHHHHHH
LTLIYTSGTTGQPKGVMLDYTNVGYQLKGHDERLSLSKDDVSLCFLPLSHVFERAWTFYV
HHHHHCCCCCCCCCCEEEEECCCCEEECCCCCCCCCCCCCCCEEEHHHHHHHHHHHEEEE
LYKGATNCYLQDTMQVRDALSDVKPTVMSAVPRFYEKIFSAIHEKVSKAPFIRKVLFTWA
EEECCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHH
VNMGAKLSVCHQEGRTPSFMLKKSHALADKLVLSKLRALLGGNINFMPCGGAKLDETIGR
HCCCCEEEEHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCHHHHHHHH
FFHAIGINVKLGYGMTETTATVSCWDDRCFNPDSIGMSMPGAEVKIGAKDEILVRGPMVM
HHHHHCCEEEECCCCCCCCEEEEECCCCCCCCCCCCCCCCCCEEEECCCCCEEEECCHHH
RGYYKMPEETAKTFDEHGFLKTGDAGHFDENGNLFITDRIKELMKTSGGKYIAPQVVEGA
HHHHCCCHHHHHHHHHCCCEECCCCCCCCCCCCEEEHHHHHHHHHCCCCCEECHHHHHCC
IGKDHFIEQIAVIADTRKFVSALIVPCYDSLEEYAKELNIKYHDRVELVKNHQIVEMLEK
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCHHHHHHHHH
RVNDLQQELAKFEQVKKFKLLPKAFSMDDGELTPTQKLRRKVINDKYQDEIEEMYNEKPK
HHHHHHHHHHHHHHHHHHHHCCHHCCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHCCCCC
DK
CC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]