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The map label for this gene is sdcS [H]

Identifier: 218708314

GI number: 218708314

Start: 249762

End: 251192

Strand: Reverse

Name: sdcS [H]

Synonym: VS_0252

Alternate gene names: 218708314

Gene position: 251192-249762 (Counterclockwise)

Preceding gene: 218708315

Following gene: 218708313

Centisome position: 7.61

GC content: 47.1

Gene sequence:

>1431_bases
ATGGGGTCTTTGTACATGCCTAAACTCAATATTGGCGTTCTGGTCAAGCTGTTGATTTGTTTTGCGATTCCCTTAGGCGT
GTTATTCATGCCAATAGATTCCATACCTATCGATGACCTCACGCTGATTCAACACCGCTTGTTGGCGATATTCTTACTAG
CAGCTCTACTGTGGGTGCTTGAACCCGTTCCAGTATTCGCCACGTCAATTCTGATCATTGCCCTTGAACTGGTGATGATT
TCCGACAAGGGTTTACATCTATTTAGAAACCCACCAGCAGGACACGATCTCGGTGAATTAATCAAATATACCGACATCTT
CGGTGCATTTTCGTCACCAATCATCATCCTTTTCATGGGTGGCTTTGCTCTTGCGATATCCGCATCCAAATACGAACTCG
ACAACAATTTAGCTCGCGTGCTGCTCAAACCATTTGGCACAGAACCGCGCTTTATTATGCTGGGTTTAATGCTTATCACC
GCCGTGTTCTCAATGTTCATGTCAAATACCGCAACAACGGTAATGATGCTCGCATTGCTAGGTCCTATCGTAGCCTCTGC
ACCAAAAGGCGACATGGGGATTAAAGCGCTCGTGTTGTGTATTCCAATCGCCGCCAATACCGGTGGTATCGCGACACCCA
TAGGTACACCACCCAATGCGATCGCACTGCAATACCTAACTGGCGAGAACAGTATCGACTTTCTTAGCTGGATGATGATG
GGCTTACCCTTTGTGATCATCCAACTCACCATCGCTTGGTTTCTCCTACAAAAACTCTTCCCTTCTAAAGAAAGAAATAT
GGTTCTCAAGCTTGATGGACAATTTAGAAAGAGCTGGCGAGCGATTGTGGTTTACGTCACCTTCGCTGCGACAATCTTAT
TGTGGATGACCACCAAACTGCATGGCATGAACACTTATGTGGTCTCTATCATTCCACTGGCTGTTTTTACTCTCACTGGC
ATCATGGGTAAAGAAGAACTCAAGCTGATTAACTGGGATGTGTTGTGGCTGGTTGCGGGTGGTATTGCGATTGGGATTGG
CTTGGATAAAACAGGCTTAGCCGCTGCACTCGCACACGCGATTGATTATGAATCGCTCTCGCCGACTGCTGTGGTACTAA
CGCTGTCTATCGTGTGTTGGCTAATGGCTAATTTCATGTCGAACACAGCTACCGCAAACTTGCTGATGCCGATAGCAGCT
GCGATTGGCGCTTCTATGGAAAGCCTAGTAGCAATTGGAGGCTTACAAGGCTTGCTGGTTGTGGTCGCCTTCTCGGCATC
GCTCGGGATGATTCTTCCAGTATCGACGCCACCAAACTCGCTGGCTTACTCAACTGGGCTTATCGAAAGCAAAGATATGG
CGAAGATGGGTATCATCTTAGGGATTGTCGGCTTACTGATGGTCTACCTCGCGCTGTTTATTATCACTTAG

Upstream 100 bases:

>100_bases
CAAAACAACTGTCGAAACCTTAAACAACTTTTCGATTTTACAACCCGTCTCCAAGTACCAAAAATCCAGATAACTTACTC
TATTTGAAGATATTTTATTC

Downstream 100 bases:

>100_bases
CACGTCAATGCCTCCCTTCCGTCCAGCTAGTAATCGTGACCTCGCTAGCTGGCGGGCTACCAGATTTTAACCAATAAGAT
AAATCCTGATAACAATTAAT

Product: putative transporter

Products: NA

Alternate protein names: Na(+)/dicarboxylate symporter [H]

Number of amino acids: Translated: 476; Mature: 475

Protein sequence:

>476_residues
MGSLYMPKLNIGVLVKLLICFAIPLGVLFMPIDSIPIDDLTLIQHRLLAIFLLAALLWVLEPVPVFATSILIIALELVMI
SDKGLHLFRNPPAGHDLGELIKYTDIFGAFSSPIIILFMGGFALAISASKYELDNNLARVLLKPFGTEPRFIMLGLMLIT
AVFSMFMSNTATTVMMLALLGPIVASAPKGDMGIKALVLCIPIAANTGGIATPIGTPPNAIALQYLTGENSIDFLSWMMM
GLPFVIIQLTIAWFLLQKLFPSKERNMVLKLDGQFRKSWRAIVVYVTFAATILLWMTTKLHGMNTYVVSIIPLAVFTLTG
IMGKEELKLINWDVLWLVAGGIAIGIGLDKTGLAAALAHAIDYESLSPTAVVLTLSIVCWLMANFMSNTATANLLMPIAA
AIGASMESLVAIGGLQGLLVVVAFSASLGMILPVSTPPNSLAYSTGLIESKDMAKMGIILGIVGLLMVYLALFIIT

Sequences:

>Translated_476_residues
MGSLYMPKLNIGVLVKLLICFAIPLGVLFMPIDSIPIDDLTLIQHRLLAIFLLAALLWVLEPVPVFATSILIIALELVMI
SDKGLHLFRNPPAGHDLGELIKYTDIFGAFSSPIIILFMGGFALAISASKYELDNNLARVLLKPFGTEPRFIMLGLMLIT
AVFSMFMSNTATTVMMLALLGPIVASAPKGDMGIKALVLCIPIAANTGGIATPIGTPPNAIALQYLTGENSIDFLSWMMM
GLPFVIIQLTIAWFLLQKLFPSKERNMVLKLDGQFRKSWRAIVVYVTFAATILLWMTTKLHGMNTYVVSIIPLAVFTLTG
IMGKEELKLINWDVLWLVAGGIAIGIGLDKTGLAAALAHAIDYESLSPTAVVLTLSIVCWLMANFMSNTATANLLMPIAA
AIGASMESLVAIGGLQGLLVVVAFSASLGMILPVSTPPNSLAYSTGLIESKDMAKMGIILGIVGLLMVYLALFIIT
>Mature_475_residues
GSLYMPKLNIGVLVKLLICFAIPLGVLFMPIDSIPIDDLTLIQHRLLAIFLLAALLWVLEPVPVFATSILIIALELVMIS
DKGLHLFRNPPAGHDLGELIKYTDIFGAFSSPIIILFMGGFALAISASKYELDNNLARVLLKPFGTEPRFIMLGLMLITA
VFSMFMSNTATTVMMLALLGPIVASAPKGDMGIKALVLCIPIAANTGGIATPIGTPPNAIALQYLTGENSIDFLSWMMMG
LPFVIIQLTIAWFLLQKLFPSKERNMVLKLDGQFRKSWRAIVVYVTFAATILLWMTTKLHGMNTYVVSIIPLAVFTLTGI
MGKEELKLINWDVLWLVAGGIAIGIGLDKTGLAAALAHAIDYESLSPTAVVLTLSIVCWLMANFMSNTATANLLMPIAAA
IGASMESLVAIGGLQGLLVVVAFSASLGMILPVSTPPNSLAYSTGLIESKDMAKMGIILGIVGLLMVYLALFIIT

Specific function: Mediates the transport of dicarboxylates across the cytoplasmic membrane via a Na(+)-electrochemical gradient [H]

COG id: COG0471

COG function: function code P; Di- and tricarboxylate transporters

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the SLC13A transporter (TC 2.A.47) family. NADC subfamily [H]

Homologues:

Organism=Homo sapiens, GI29171306, Length=535, Percent_Identity=25.981308411215, Blast_Score=124, Evalue=2e-28,
Organism=Homo sapiens, GI301069349, Length=307, Percent_Identity=25.4071661237785, Blast_Score=89, Evalue=1e-17,
Organism=Homo sapiens, GI31795546, Length=344, Percent_Identity=24.4186046511628, Blast_Score=85, Evalue=1e-16,
Organism=Homo sapiens, GI219802232, Length=463, Percent_Identity=24.622030237581, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI19923838, Length=343, Percent_Identity=24.7813411078717, Blast_Score=77, Evalue=3e-14,
Organism=Homo sapiens, GI31377715, Length=150, Percent_Identity=29.3333333333333, Blast_Score=75, Evalue=9e-14,
Organism=Homo sapiens, GI301069346, Length=150, Percent_Identity=29.3333333333333, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI58761541, Length=150, Percent_Identity=29.3333333333333, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI301069353, Length=152, Percent_Identity=30.2631578947368, Blast_Score=75, Evalue=2e-13,
Organism=Homo sapiens, GI4506979, Length=160, Percent_Identity=30, Blast_Score=70, Evalue=4e-12,
Organism=Homo sapiens, GI225637552, Length=160, Percent_Identity=30, Blast_Score=70, Evalue=5e-12,
Organism=Homo sapiens, GI225637549, Length=160, Percent_Identity=30, Blast_Score=70, Evalue=5e-12,
Organism=Escherichia coli, GI1786829, Length=483, Percent_Identity=24.223602484472, Blast_Score=63, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI32565804, Length=420, Percent_Identity=27.3809523809524, Blast_Score=125, Evalue=7e-29,
Organism=Caenorhabditis elegans, GI71988385, Length=420, Percent_Identity=27.3809523809524, Blast_Score=124, Evalue=1e-28,
Organism=Caenorhabditis elegans, GI71989118, Length=470, Percent_Identity=24.8936170212766, Blast_Score=115, Evalue=5e-26,
Organism=Caenorhabditis elegans, GI32564681, Length=519, Percent_Identity=22.7360308285164, Blast_Score=93, Evalue=2e-19,
Organism=Saccharomyces cerevisiae, GI6324340, Length=414, Percent_Identity=29.951690821256, Blast_Score=153, Evalue=7e-38,
Organism=Saccharomyces cerevisiae, GI6319885, Length=420, Percent_Identity=27.8571428571429, Blast_Score=120, Evalue=7e-28,
Organism=Saccharomyces cerevisiae, GI6322263, Length=416, Percent_Identity=28.125, Blast_Score=117, Evalue=5e-27,
Organism=Drosophila melanogaster, GI281366409, Length=509, Percent_Identity=23.5756385068762, Blast_Score=89, Evalue=9e-18,
Organism=Drosophila melanogaster, GI17737623, Length=509, Percent_Identity=23.5756385068762, Blast_Score=89, Evalue=9e-18,
Organism=Drosophila melanogaster, GI24666468, Length=509, Percent_Identity=23.5756385068762, Blast_Score=89, Evalue=9e-18,
Organism=Drosophila melanogaster, GI45551633, Length=509, Percent_Identity=23.5756385068762, Blast_Score=88, Evalue=1e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001898 [H]

Pfam domain/function: PF00939 Na_sulph_symp [H]

EC number: NA

Molecular weight: Translated: 51115; Mature: 50984

Theoretical pI: Translated: 7.04; Mature: 7.04

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
5.7 %Met     (Translated Protein)
6.3 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
5.5 %Met     (Mature Protein)
6.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGSLYMPKLNIGVLVKLLICFAIPLGVLFMPIDSIPIDDLTLIQHRLLAIFLLAALLWVL
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
EPVPVFATSILIIALELVMISDKGLHLFRNPPAGHDLGELIKYTDIFGAFSSPIIILFMG
CCHHHHHHHHHHHHHHHHHCCCCCCEEECCCCCCCCHHHHHHHHHHHHHHCCCEEEEEEC
GFALAISASKYELDNNLARVLLKPFGTEPRFIMLGLMLITAVFSMFMSNTATTVMMLALL
CHHHEEECHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHH
GPIVASAPKGDMGIKALVLCIPIAANTGGIATPIGTPPNAIALQYLTGENSIDFLSWMMM
HHHHHCCCCCCCCHHHHHHHEEHCCCCCCCCCCCCCCCCCEEEEEEECCCCHHHHHHHHH
GLPFVIIQLTIAWFLLQKLFPSKERNMVLKLDGQFRKSWRAIVVYVTFAATILLWMTTKL
HHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHH
HGMNTYVVSIIPLAVFTLTGIMGKEELKLINWDVLWLVAGGIAIGIGLDKTGLAAALAHA
CCCHHHHHHHHHHHHHHHHHCCCCCCEEEECHHHHHHHHCCEEEEECCCCHHHHHHHHHH
IDYESLSPTAVVLTLSIVCWLMANFMSNTATANLLMPIAAAIGASMESLVAIGGLQGLLV
HCCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCHHHHHHHCCHHHHHH
VVAFSASLGMILPVSTPPNSLAYSTGLIESKDMAKMGIILGIVGLLMVYLALFIIT
HHHHHCCCCEEEECCCCCCCHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
GSLYMPKLNIGVLVKLLICFAIPLGVLFMPIDSIPIDDLTLIQHRLLAIFLLAALLWVL
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
EPVPVFATSILIIALELVMISDKGLHLFRNPPAGHDLGELIKYTDIFGAFSSPIIILFMG
CCHHHHHHHHHHHHHHHHHCCCCCCEEECCCCCCCCHHHHHHHHHHHHHHCCCEEEEEEC
GFALAISASKYELDNNLARVLLKPFGTEPRFIMLGLMLITAVFSMFMSNTATTVMMLALL
CHHHEEECHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHH
GPIVASAPKGDMGIKALVLCIPIAANTGGIATPIGTPPNAIALQYLTGENSIDFLSWMMM
HHHHHCCCCCCCCHHHHHHHEEHCCCCCCCCCCCCCCCCCEEEEEEECCCCHHHHHHHHH
GLPFVIIQLTIAWFLLQKLFPSKERNMVLKLDGQFRKSWRAIVVYVTFAATILLWMTTKL
HHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHH
HGMNTYVVSIIPLAVFTLTGIMGKEELKLINWDVLWLVAGGIAIGIGLDKTGLAAALAHA
CCCHHHHHHHHHHHHHHHHHCCCCCCEEEECHHHHHHHHCCEEEEECCCCHHHHHHHHHH
IDYESLSPTAVVLTLSIVCWLMANFMSNTATANLLMPIAAAIGASMESLVAIGGLQGLLV
HCCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCHHHHHHHCCHHHHHH
VVAFSASLGMILPVSTPPNSLAYSTGLIESKDMAKMGIILGIVGLLMVYLALFIIT
HHHHHCCCCEEEECCCCCCCHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA