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The map label for this gene is acrR [H]

Identifier: 218691130

GI number: 218691130

Start: 3412335

End: 3412706

Strand: Reverse

Name: acrR [H]

Synonym: ECED1_3475

Alternate gene names: 218691130

Gene position: 3412706-3412335 (Counterclockwise)

Preceding gene: 218691131

Following gene: 218691129

Centisome position: 65.51

GC content: 42.74

Gene sequence:

>372_bases
ATGTCAATGGAGATTTCAACAGTGGTGCGGCACACAAAATTTGCAGCGGAAGAAACCCGCAAACAAATCCTGGATGTGGC
AGAGTTCTGCTTTTGTGAGACGGGCTTTTCGAAGACGACACTGGAGATGATTGCGGCGCGCGCAGGTTGTACTCGGGGGG
CCATATACTGGTATTTCAACGAAAAAAAAGATCTTCTGCGACAAGTCATCGAGCGGGTACCACTATCATTATTTGATGAG
CTTACAGCCATCAAAAATGGGAGAGTTTCTGAACCGGTTAAAGCGATGTATCGTTGCTTATCACGTAGCCTGATTAAATT
ACAATATAATGTACACTTACGGAATGTAATTTATATTGTGTTTTTTTTGTGA

Upstream 100 bases:

>100_bases
AGCATGAGTAAATATTCAGGTGCAGTAAACAACATACTGCGCCTGAGTAAATGGCTGTTGGGTTGGTACTAAATGCCCCA
GAGATATTTCCTGAAATAAG

Downstream 100 bases:

>100_bases
AGAATGTCCGGATGATATAAGAATAAATTTCTTACAAAAAATGGTGGATGTCAATAATTTTGTAAAATTACTATGTTATA
TTTTCGAAAAAGGTAAGTTA

Product: hypothetical protein

Products: NA

Alternate protein names: Potential acrAB operon repressor [H]

Number of amino acids: Translated: 123; Mature: 122

Protein sequence:

>123_residues
MSMEISTVVRHTKFAAEETRKQILDVAEFCFCETGFSKTTLEMIAARAGCTRGAIYWYFNEKKDLLRQVIERVPLSLFDE
LTAIKNGRVSEPVKAMYRCLSRSLIKLQYNVHLRNVIYIVFFL

Sequences:

>Translated_123_residues
MSMEISTVVRHTKFAAEETRKQILDVAEFCFCETGFSKTTLEMIAARAGCTRGAIYWYFNEKKDLLRQVIERVPLSLFDE
LTAIKNGRVSEPVKAMYRCLSRSLIKLQYNVHLRNVIYIVFFL
>Mature_122_residues
SMEISTVVRHTKFAAEETRKQILDVAEFCFCETGFSKTTLEMIAARAGCTRGAIYWYFNEKKDLLRQVIERVPLSLFDEL
TAIKNGRVSEPVKAMYRCLSRSLIKLQYNVHLRNVIYIVFFL

Specific function: Potential regulator protein for the acrAB genes [H]

COG id: COG1309

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH tetR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1786669, Length=64, Percent_Identity=51.5625, Blast_Score=69, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009057
- InterPro:   IPR012287
- InterPro:   IPR015893
- InterPro:   IPR011075
- InterPro:   IPR013572
- InterPro:   IPR001647 [H]

Pfam domain/function: PF08361 TetR_C_2; PF00440 TetR_N [H]

EC number: NA

Molecular weight: Translated: 14322; Mature: 14191

Theoretical pI: Translated: 9.23; Mature: 9.23

Prosite motif: PS50977 HTH_TETR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.3 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
6.5 %Cys+Met (Translated Protein)
3.3 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSMEISTVVRHTKFAAEETRKQILDVAEFCFCETGFSKTTLEMIAARAGCTRGAIYWYFN
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCEEEEEEC
EKKDLLRQVIERVPLSLFDELTAIKNGRVSEPVKAMYRCLSRSLIKLQYNVHLRNVIYIV
CHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHEEE
FFL
EEC
>Mature Secondary Structure 
SMEISTVVRHTKFAAEETRKQILDVAEFCFCETGFSKTTLEMIAARAGCTRGAIYWYFN
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCEEEEEEC
EKKDLLRQVIERVPLSLFDELTAIKNGRVSEPVKAMYRCLSRSLIKLQYNVHLRNVIYIV
CHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHEEE
FFL
EEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]