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The map label for this gene is mexB [H]

Identifier: 218689284

GI number: 218689284

Start: 1473672

End: 1476779

Strand: Direct

Name: mexB [H]

Synonym: ECED1_1502

Alternate gene names: 218689284

Gene position: 1473672-1476779 (Clockwise)

Preceding gene: 218689283

Following gene: 218689285

Centisome position: 28.29

GC content: 51.99

Gene sequence:

>3108_bases
ATGTTTTCGCGCTTTTTTGTTCGCCGCCCGGTCTTTGCCTGGGTTATCGCCATTTTGATTATGTTGGCGGGGATTCTGGC
TATTCGCACATTGCCCGTCGCGCAATATCCTGACGTTGCGCCACCGACCATTAAAATTTCAGCCACTTATACTGGTGCTT
CTGCCGAAACGCTGGAGAACAGCGTGACTCAGGTTATCGAGCAACAACTCACTGGGCTTGATAATTTACTCTATTTCAGC
TCAACCAGCAGCTCTGATGGTTCGGTCAGTATTAATGTGACCTTTGAACAAGGTACCGATCCAGATACTGCACAGGTTCA
GGTGCAGAATAAAATTCAGCAGGCGGAGTCGCGCCTACCCAGCGAAGTGCAGCAAACGGGTGTTACGGTGGAGAAATCAC
AAAGCAACTTTTTGCTGATTGCTGCCGTGTATGACACCACTGACAAAGCCTCCAGTTCGGATATCGCCGACTGGCTGGTC
AGTAACGTTCAGGACCCGCTGGCGCGTGTTGAAGGTGTGGGGAGTCTGCAAGTCTTTGGCGCGGAATACGCTATGCGCAT
CTGGCTCGACCCGGCCAAACTGGCGTCTTACTCGCTGATGCCTTCAGACGTGCAAAGTGCTATTGAAGCGCAAAACGTGC
AGGTTACTGCCGGGAAAATAGGGGCATTGCCTTCACCGGATACTCAGCAACTGACCGCAACGGTACGTGCGCAGTCTCGT
TTGCAGACGGTGGATCAGTTCAAAAATATTATCGTGAAAAGCCAGTCAGACGGCGCAGTTGTTCGTATAAAAGATGTGGC
TCGCGTTGAGATGGGCAGTGAAGATTATACCGCTATCGGCAAACTTAACGGTCACCCGTCTGCCGGGGTTGCTGTAATGC
TTTCGCCCGGTGCGAATGCGCTGAATACGGCGACGCTGGTCAAGGATAAGATTGCCGAATTCCAGCGGAACATGCCGCAG
GGATACGACATCGCATACCCGAAAGACAGCACTGAATTTATTAAAATCTCCGTAGAGGACGTAATTCAGACGCTGTTTGA
AGCCATCGTATTGGTGGTTTGCGTGATGTATTTATTCCTGCAAAACCTGCGTGCCACACTGATTCCGGCGTTAGCTGTCC
CCGTCGTTTTGCTGGGCACATTCGGCGTTCTTGCGTTGTTTGGCTATTCGATTAATACCCTGACGTTGTTTGCAATGGTG
CAGGCGATCGGCTTGCTGGTGGACGATGCCATTGTGGTGGTAGAGAACGTCGAACGCATTATGCGTGACGAAGGGTTGCC
CGCGCCTGAAGCCACGGAAAAATCAATGGGCGAGATTTCTGGCGCACTGGTTGCCATTGCGCTGGTGTTGTCAGCCGTAT
TCCTGCCGATGGCCTTCTTTGGGGGATCTACGGGCGTAATTTATCGTCAGTTCTCCATCACCATTATCTCCGCAATGCTG
CTTTCCGTGGTGGTGGCATTGACCTTGACTCCCGCCCTGTGCGGTTCCGTCCTCCAGCATGTTCCACCACATAAAAAAGG
CTTTTTCGGCGCATTTAACCGCTTTTACCGCCGTACTGAAGATAAATATCAGCGAGGCGTAATTTATGTCCTGCGCCGTA
CAGCCCGAACGATGGGGCTTTATGTCGTGCTGGGTGGTGGAATGGCCCTGATGATGTGGAAACTGCCGGGCAGTTTCTTA
CCCACTGAAGACCAGGGCGAAATCATGGTGCAGTACACGCTGCCGGCCGGTGCAACCGCTGCCCGTACAGCAGAAGTGAA
TCGCCAGATTGTTGACTGGTTCCTGATTAACGAGAAAGCAAATACCGATGTCATCTTTACCGTTGATGGTTTCAGTTTTA
GCGGCAGCGGACAGAACACCGGGATGGCGTTTGTTTCGTTGAAAAACTGGTCTCAACGTAAAGGGGCAGAAAACACCGCC
CAGGCTATCGCCCTACGGGCAACCAAAGAGCTGGGCACAATTCGTGATGCCACGGTATTTGCGATGACGCCGCCAGCCGT
TGATGGGCTGGGGCAAAGCAATGGTTTTACGTTTGAATTGTTAGCTAACGGTGGAACCGATCGTGAAACACTGCTGCAAA
TGCGTAATCAGTTGATAGAAAAAGCGAATCAAAGTCCGGAGTTACATTCTGTACGCGCCAATGATTTGCCACAAATGCCG
CAATTGCAGGTAGATATTGATAGTAATAAAGCGGTGTCATTAGGGTTGAGTTTGAATGATGTCACCGACACCCTGTCCAG
TGCGTGGGGCGGTACTTATGTGAATGACTTTATTGACCGTGGTCGTGTGAAAAAAGTCTACATTCAGGGCGACAGCGAAT
TTCGTTCCGCGCCGTCAGACTTAGGTAAATGGTTTGTGCGCGGTAGCGATAACGCCATGACACCATTCTCTGCTTTTGCG
ACCACCCGCTGGCTGTATGGACCGGAAAGACTGGTGCGCTACAACGGCTCGGCAGCCTATGAAATTCAGGGCGAAAACGC
GACTGGCTTTAGTTCCGGCGATGCAATGACAAAAATGGAGGAACTGGCAAACAGTCTTCCTGCGGGAACAACCTGGGCCT
GGAGTGGTTTGTCATTGCAGGAGAAACTGGCCAGCGGTCAGGCATTAAGTCTGTATGCAGTTTCTATTCTGGTGGTTTTC
CTCTGCCTTGCAGCACTGTACGAAAGCTGGTCAGTCCCGTTCTCGGTCATTCTGGTGATCCCTCTGGGGCTTCTTGGCGC
GGCGCTGGCGGCCTGGATGCGTGATTTAAACAACGACGTTTACTTCCAGGTAGCGCTATTAACTACTATCGGCTTGTCGT
CGAAAAACGCCATTCTGATTGTGGAATTTGCTGAAGCGGCGGTTGCAGAGGGCTATTCCTTGAGTCGTGCGGCATTACGC
GCGGCGCAGACTCGTTTACGCCCAATCATCATGACCTCGCTGGCGTTTATTGCGGGGGTAATGCCGCTGGCGATAGCAAC
CGGCGCAGGGGCGAACAGCCGCATCGCCATTGGTACGGGCATTATTGGCGGCACGCTGACCGCTACATTACTGGCCATTT
TCTTCGTTCCTCTGTTTTTTGTACTGGTGAAACGTTTGTTTGCCGGTAAACCGCGCCGTCAGGAGTAA

Upstream 100 bases:

>100_bases
TGCACAACGGCGACCGACTGATTGTTGAAGGTTCTGCCAAAGTCACTTCAGGGCAGACCGTCAAGGCTGTTGAAGTTCAG
GCTAATGGAGGCAACGCCTG

Downstream 100 bases:

>100_bases
GTTATGTTGCGTCGTTCTCTTATTTTTCTGGTGTTGTTGAGTGCGGGATGTGTCTCGCTCGATCCTCACTACAGTACGCC
TGAATCCCCAATCCCGGCGA

Product: putative efflux pump

Products: Proton [Cytoplasm]; multidrug [Periplasm] [C]

Alternate protein names: Multidrug-efflux transporter MexB [H]

Number of amino acids: Translated: 1035; Mature: 1035

Protein sequence:

>1035_residues
MFSRFFVRRPVFAWVIAILIMLAGILAIRTLPVAQYPDVAPPTIKISATYTGASAETLENSVTQVIEQQLTGLDNLLYFS
STSSSDGSVSINVTFEQGTDPDTAQVQVQNKIQQAESRLPSEVQQTGVTVEKSQSNFLLIAAVYDTTDKASSSDIADWLV
SNVQDPLARVEGVGSLQVFGAEYAMRIWLDPAKLASYSLMPSDVQSAIEAQNVQVTAGKIGALPSPDTQQLTATVRAQSR
LQTVDQFKNIIVKSQSDGAVVRIKDVARVEMGSEDYTAIGKLNGHPSAGVAVMLSPGANALNTATLVKDKIAEFQRNMPQ
GYDIAYPKDSTEFIKISVEDVIQTLFEAIVLVVCVMYLFLQNLRATLIPALAVPVVLLGTFGVLALFGYSINTLTLFAMV
QAIGLLVDDAIVVVENVERIMRDEGLPAPEATEKSMGEISGALVAIALVLSAVFLPMAFFGGSTGVIYRQFSITIISAML
LSVVVALTLTPALCGSVLQHVPPHKKGFFGAFNRFYRRTEDKYQRGVIYVLRRTARTMGLYVVLGGGMALMMWKLPGSFL
PTEDQGEIMVQYTLPAGATAARTAEVNRQIVDWFLINEKANTDVIFTVDGFSFSGSGQNTGMAFVSLKNWSQRKGAENTA
QAIALRATKELGTIRDATVFAMTPPAVDGLGQSNGFTFELLANGGTDRETLLQMRNQLIEKANQSPELHSVRANDLPQMP
QLQVDIDSNKAVSLGLSLNDVTDTLSSAWGGTYVNDFIDRGRVKKVYIQGDSEFRSAPSDLGKWFVRGSDNAMTPFSAFA
TTRWLYGPERLVRYNGSAAYEIQGENATGFSSGDAMTKMEELANSLPAGTTWAWSGLSLQEKLASGQALSLYAVSILVVF
LCLAALYESWSVPFSVILVIPLGLLGAALAAWMRDLNNDVYFQVALLTTIGLSSKNAILIVEFAEAAVAEGYSLSRAALR
AAQTRLRPIIMTSLAFIAGVMPLAIATGAGANSRIAIGTGIIGGTLTATLLAIFFVPLFFVLVKRLFAGKPRRQE

Sequences:

>Translated_1035_residues
MFSRFFVRRPVFAWVIAILIMLAGILAIRTLPVAQYPDVAPPTIKISATYTGASAETLENSVTQVIEQQLTGLDNLLYFS
STSSSDGSVSINVTFEQGTDPDTAQVQVQNKIQQAESRLPSEVQQTGVTVEKSQSNFLLIAAVYDTTDKASSSDIADWLV
SNVQDPLARVEGVGSLQVFGAEYAMRIWLDPAKLASYSLMPSDVQSAIEAQNVQVTAGKIGALPSPDTQQLTATVRAQSR
LQTVDQFKNIIVKSQSDGAVVRIKDVARVEMGSEDYTAIGKLNGHPSAGVAVMLSPGANALNTATLVKDKIAEFQRNMPQ
GYDIAYPKDSTEFIKISVEDVIQTLFEAIVLVVCVMYLFLQNLRATLIPALAVPVVLLGTFGVLALFGYSINTLTLFAMV
QAIGLLVDDAIVVVENVERIMRDEGLPAPEATEKSMGEISGALVAIALVLSAVFLPMAFFGGSTGVIYRQFSITIISAML
LSVVVALTLTPALCGSVLQHVPPHKKGFFGAFNRFYRRTEDKYQRGVIYVLRRTARTMGLYVVLGGGMALMMWKLPGSFL
PTEDQGEIMVQYTLPAGATAARTAEVNRQIVDWFLINEKANTDVIFTVDGFSFSGSGQNTGMAFVSLKNWSQRKGAENTA
QAIALRATKELGTIRDATVFAMTPPAVDGLGQSNGFTFELLANGGTDRETLLQMRNQLIEKANQSPELHSVRANDLPQMP
QLQVDIDSNKAVSLGLSLNDVTDTLSSAWGGTYVNDFIDRGRVKKVYIQGDSEFRSAPSDLGKWFVRGSDNAMTPFSAFA
TTRWLYGPERLVRYNGSAAYEIQGENATGFSSGDAMTKMEELANSLPAGTTWAWSGLSLQEKLASGQALSLYAVSILVVF
LCLAALYESWSVPFSVILVIPLGLLGAALAAWMRDLNNDVYFQVALLTTIGLSSKNAILIVEFAEAAVAEGYSLSRAALR
AAQTRLRPIIMTSLAFIAGVMPLAIATGAGANSRIAIGTGIIGGTLTATLLAIFFVPLFFVLVKRLFAGKPRRQE
>Mature_1035_residues
MFSRFFVRRPVFAWVIAILIMLAGILAIRTLPVAQYPDVAPPTIKISATYTGASAETLENSVTQVIEQQLTGLDNLLYFS
STSSSDGSVSINVTFEQGTDPDTAQVQVQNKIQQAESRLPSEVQQTGVTVEKSQSNFLLIAAVYDTTDKASSSDIADWLV
SNVQDPLARVEGVGSLQVFGAEYAMRIWLDPAKLASYSLMPSDVQSAIEAQNVQVTAGKIGALPSPDTQQLTATVRAQSR
LQTVDQFKNIIVKSQSDGAVVRIKDVARVEMGSEDYTAIGKLNGHPSAGVAVMLSPGANALNTATLVKDKIAEFQRNMPQ
GYDIAYPKDSTEFIKISVEDVIQTLFEAIVLVVCVMYLFLQNLRATLIPALAVPVVLLGTFGVLALFGYSINTLTLFAMV
QAIGLLVDDAIVVVENVERIMRDEGLPAPEATEKSMGEISGALVAIALVLSAVFLPMAFFGGSTGVIYRQFSITIISAML
LSVVVALTLTPALCGSVLQHVPPHKKGFFGAFNRFYRRTEDKYQRGVIYVLRRTARTMGLYVVLGGGMALMMWKLPGSFL
PTEDQGEIMVQYTLPAGATAARTAEVNRQIVDWFLINEKANTDVIFTVDGFSFSGSGQNTGMAFVSLKNWSQRKGAENTA
QAIALRATKELGTIRDATVFAMTPPAVDGLGQSNGFTFELLANGGTDRETLLQMRNQLIEKANQSPELHSVRANDLPQMP
QLQVDIDSNKAVSLGLSLNDVTDTLSSAWGGTYVNDFIDRGRVKKVYIQGDSEFRSAPSDLGKWFVRGSDNAMTPFSAFA
TTRWLYGPERLVRYNGSAAYEIQGENATGFSSGDAMTKMEELANSLPAGTTWAWSGLSLQEKLASGQALSLYAVSILVVF
LCLAALYESWSVPFSVILVIPLGLLGAALAAWMRDLNNDVYFQVALLTTIGLSSKNAILIVEFAEAAVAEGYSLSRAALR
AAQTRLRPIIMTSLAFIAGVMPLAIATGAGANSRIAIGTGIIGGTLTATLLAIFFVPLFFVLVKRLFAGKPRRQE

Specific function: The ability to export antibiotics and solvents is dramatically decreased in the presence of the proton conductor carbonyl cyanide m-chlorophenylhydrazone (CCCP), showing that an energized inner membrane is required for efflux. It is thought that the MexB

COG id: COG0841

COG function: function code V; Cation/multidrug efflux pump

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AcrB/AcrD/AcrF (TC 2.A.6) family [H]

Homologues:

Organism=Escherichia coli, GI1786667, Length=1017, Percent_Identity=56.9321533923304, Blast_Score=1186, Evalue=0.0,
Organism=Escherichia coli, GI1789666, Length=1033, Percent_Identity=56.5343659244918, Blast_Score=1172, Evalue=0.0,
Organism=Escherichia coli, GI1788814, Length=1036, Percent_Identity=55.3088803088803, Blast_Score=1164, Evalue=0.0,
Organism=Escherichia coli, GI1789930, Length=1032, Percent_Identity=54.6511627906977, Blast_Score=1108, Evalue=0.0,
Organism=Escherichia coli, GI1788390, Length=1035, Percent_Identity=29.6618357487923, Blast_Score=397, Evalue=1e-111,
Organism=Escherichia coli, GI1788391, Length=1049, Percent_Identity=30.2192564346997, Blast_Score=372, Evalue=1e-104,
Organism=Escherichia coli, GI1786788, Length=1049, Percent_Identity=24.1182078169685, Blast_Score=239, Evalue=9e-64,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001036
- InterPro:   IPR004764 [H]

Pfam domain/function: PF00873 ACR_tran [H]

EC number: NA

Molecular weight: Translated: 111626; Mature: 111626

Theoretical pI: Translated: 5.15; Mature: 5.15

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFSRFFVRRPVFAWVIAILIMLAGILAIRTLPVAQYPDVAPPTIKISATYTGASAETLEN
CCCCHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEEECCCCHHHHHH
SVTQVIEQQLTGLDNLLYFSSTSSSDGSVSINVTFEQGTDPDTAQVQVQNKIQQAESRLP
HHHHHHHHHHCCCHHEEEEECCCCCCCEEEEEEEEECCCCCCHHHHHHHHHHHHHHHHCC
SEVQQTGVTVEKSQSNFLLIAAVYDTTDKASSSDIADWLVSNVQDPLARVEGVGSLQVFG
HHHHHCCCEEEECCCCEEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEC
AEYAMRIWLDPAKLASYSLMPSDVQSAIEAQNVQVTAGKIGALPSPDTQQLTATVRAQSR
CCEEEEEEECHHHHHHCCCCHHHHHHHHHHCCEEEECCCCCCCCCCCHHHHHHHHHHHHH
LQTVDQFKNIIVKSQSDGAVVRIKDVARVEMGSEDYTAIGKLNGHPSAGVAVMLSPGANA
HHHHHHHHHHEEECCCCCCEEEEECHHHHHCCCCCCEEEECCCCCCCCCEEEEECCCCCC
LNTATLVKDKIAEFQRNMPQGYDIAYPKDSTEFIKISVEDVIQTLFEAIVLVVCVMYLFL
HHHHHHHHHHHHHHHHCCCCCCEECCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHH
QNLRATLIPALAVPVVLLGTFGVLALFGYSINTLTLFAMVQAIGLLVDDAIVVVENVERI
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MRDEGLPAPEATEKSMGEISGALVAIALVLSAVFLPMAFFGGSTGVIYRQFSITIISAML
HHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEHHHHHHHHHHH
LSVVVALTLTPALCGSVLQHVPPHKKGFFGAFNRFYRRTEDKYQRGVIYVLRRTARTMGL
HHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHEE
YVVLGGGMALMMWKLPGSFLPTEDQGEIMVQYTLPAGATAARTAEVNRQIVDWFLINEKA
EEEECCCCEEEEEECCCCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHEEEEEEECCCC
NTDVIFTVDGFSFSGSGQNTGMAFVSLKNWSQRKGAENTAQAIALRATKELGTIRDATVF
CCCEEEEEECCEECCCCCCCCEEEEEECCCHHHCCCCHHHHHHHHHHHHHHCCCCCCEEE
AMTPPAVDGLGQSNGFTFELLANGGTDRETLLQMRNQLIEKANQSPELHSVRANDLPQMP
EECCCCCCCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHCCCCCCEECCCCCCCCCCC
QLQVDIDSNKAVSLGLSLNDVTDTLSSAWGGTYVNDFIDRGRVKKVYIQGDSEFRSAPSD
CEEEEECCCCEEEEECCHHHHHHHHHHHCCCHHHHHHHCCCCEEEEEEECCHHHHCCHHH
LGKWFVRGSDNAMTPFSAFATTRWLYGPERLVRYNGSAAYEIQGENATGFSSGDAMTKME
HHHHEEECCCCCCCCHHHHHHHHHCCCCHHHEEECCCEEEEEECCCCCCCCCCHHHHHHH
ELANSLPAGTTWAWSGLSLQEKLASGQALSLYAVSILVVFLCLAALYESWSVPFSVILVI
HHHHHCCCCCCEEECCCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHH
PLGLLGAALAAWMRDLNNDVYFQVALLTTIGLSSKNAILIVEFAEAAVAEGYSLSRAALR
HHHHHHHHHHHHHHHCCCCCEEEEEEHHHHCCCCCCCEEEEEEHHHHHHCCCHHHHHHHH
AAQTRLRPIIMTSLAFIAGVMPLAIATGAGANSRIAIGTGIIGGTLTATLLAIFFVPLFF
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHH
VLVKRLFAGKPRRQE
HHHHHHHCCCCCCCC
>Mature Secondary Structure
MFSRFFVRRPVFAWVIAILIMLAGILAIRTLPVAQYPDVAPPTIKISATYTGASAETLEN
CCCCHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEEECCCCHHHHHH
SVTQVIEQQLTGLDNLLYFSSTSSSDGSVSINVTFEQGTDPDTAQVQVQNKIQQAESRLP
HHHHHHHHHHCCCHHEEEEECCCCCCCEEEEEEEEECCCCCCHHHHHHHHHHHHHHHHCC
SEVQQTGVTVEKSQSNFLLIAAVYDTTDKASSSDIADWLVSNVQDPLARVEGVGSLQVFG
HHHHHCCCEEEECCCCEEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEC
AEYAMRIWLDPAKLASYSLMPSDVQSAIEAQNVQVTAGKIGALPSPDTQQLTATVRAQSR
CCEEEEEEECHHHHHHCCCCHHHHHHHHHHCCEEEECCCCCCCCCCCHHHHHHHHHHHHH
LQTVDQFKNIIVKSQSDGAVVRIKDVARVEMGSEDYTAIGKLNGHPSAGVAVMLSPGANA
HHHHHHHHHHEEECCCCCCEEEEECHHHHHCCCCCCEEEECCCCCCCCCEEEEECCCCCC
LNTATLVKDKIAEFQRNMPQGYDIAYPKDSTEFIKISVEDVIQTLFEAIVLVVCVMYLFL
HHHHHHHHHHHHHHHHCCCCCCEECCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHH
QNLRATLIPALAVPVVLLGTFGVLALFGYSINTLTLFAMVQAIGLLVDDAIVVVENVERI
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MRDEGLPAPEATEKSMGEISGALVAIALVLSAVFLPMAFFGGSTGVIYRQFSITIISAML
HHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEHHHHHHHHHHH
LSVVVALTLTPALCGSVLQHVPPHKKGFFGAFNRFYRRTEDKYQRGVIYVLRRTARTMGL
HHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHEE
YVVLGGGMALMMWKLPGSFLPTEDQGEIMVQYTLPAGATAARTAEVNRQIVDWFLINEKA
EEEECCCCEEEEEECCCCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHEEEEEEECCCC
NTDVIFTVDGFSFSGSGQNTGMAFVSLKNWSQRKGAENTAQAIALRATKELGTIRDATVF
CCCEEEEEECCEECCCCCCCCEEEEEECCCHHHCCCCHHHHHHHHHHHHHHCCCCCCEEE
AMTPPAVDGLGQSNGFTFELLANGGTDRETLLQMRNQLIEKANQSPELHSVRANDLPQMP
EECCCCCCCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHCCCCCCEECCCCCCCCCCC
QLQVDIDSNKAVSLGLSLNDVTDTLSSAWGGTYVNDFIDRGRVKKVYIQGDSEFRSAPSD
CEEEEECCCCEEEEECCHHHHHHHHHHHCCCHHHHHHHCCCCEEEEEEECCHHHHCCHHH
LGKWFVRGSDNAMTPFSAFATTRWLYGPERLVRYNGSAAYEIQGENATGFSSGDAMTKME
HHHHEEECCCCCCCCHHHHHHHHHCCCCHHHEEECCCEEEEEECCCCCCCCCCHHHHHHH
ELANSLPAGTTWAWSGLSLQEKLASGQALSLYAVSILVVFLCLAALYESWSVPFSVILVI
HHHHHCCCCCCEEECCCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHH
PLGLLGAALAAWMRDLNNDVYFQVALLTTIGLSSKNAILIVEFAEAAVAEGYSLSRAALR
HHHHHHHHHHHHHHHCCCCCEEEEEEHHHHCCCCCCCEEEEEEHHHHHHCCCHHHHHHHH
AAQTRLRPIIMTSLAFIAGVMPLAIATGAGANSRIAIGTGIIGGTLTATLLAIFFVPLFF
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHH
VLVKRLFAGKPRRQE
HHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; multidrug [Cytoplasm] [C]

Specific reaction: Proton [Periplasm] + multidrug [Cytoplasm] = Proton [Cytoplasm] + multidrug [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7968531; 10984043; 9989496; 8226684; 8540696; 9603892; 10187844 [H]