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The map label for this gene is arpC [H]

Identifier: 218689285

GI number: 218689285

Start: 1476783

End: 1478156

Strand: Direct

Name: arpC [H]

Synonym: ECED1_1503

Alternate gene names: 218689285

Gene position: 1476783-1478156 (Clockwise)

Preceding gene: 218689284

Following gene: 218689286

Centisome position: 28.35

GC content: 53.42

Gene sequence:

>1374_bases
ATGTTGCGTCGTTCTCTTATTTTTCTGGTGTTGTTGAGTGCGGGATGTGTCTCGCTCGATCCTCACTACAGTACGCCTGA
ATCCCCAATCCCGGCGACCTTGCCGGGAGCACAGGACCAGGGGAAGGCAATCAGCCATGACTGGCAGCAGGTGATCCACG
ATCCCCGATTGCAGCAGGTAGTAACCATTGCACTGAACAGTAACCGCGATGTGCAAAAAGCGATTGCTGATATTGACTCA
GCACGGGCGCTCTATGGGCAAACTAATGCGTCGTTATTTCCGACGGTGAATGCGGCCTTAAGTTCGACTCGCAGTCGTTC
GATGGCGAATGGTACGGGAACAACTGCCGAGGCTGACGGCACGGTGTCCAGTTATACGTTAGATCTGTTTGGTCGTAATC
AGAGTTTATCTCGGGCGGCGCGGGAAACCTGGCTTGCCAGTGAATTTACAGCCCAGAACACTCGTTTAACGCTGATTGCT
GAAATCAGCACCGCCTGGCTGACACTGGCGGCTGATAACAGCAACCTGGCCCTGGCAAAAGAAACGATGACCAGTGCAGA
AAACTCATTGAAAATTATCCAGCGCCAGCAACAGGTTGGCACGGCGGCAGTGACAGATGTCAGTGAGGCGATGAGTGTTT
ATCAGCAAGCGCGCGCCAGCGTTGCCAGCTATCAGACACAAGTGATGCAGGATAAAAATGCGCTGAACTTACTGGCAGGT
ACAACGCTTGCGGAAAATCTGCTACCGGGAACACTGGAAAGCCTACCGGAACAAATGATAAGTCTGGTTCCTGCGGGAGT
ATCATCTGATGTTCTGCTGCGTCGCCCGGATATCCAGGAAGCGGAACATAATTTGAAGAGCGCCAATGCAGATATTGGCG
CGGCGCGGGCTAACTTTTTCCCGACGATTTCGCTGACTGCCAGTGCCGGTGTTGGCAGTGACGCATTGTCGTCGTTGTTC
AGCCACGGAATGCAGATCTGGTCATTTGCGCCATCGGTCACATTATCGCTGTTCACTGGCGGAAGTAATCTGGCGCAGCT
TCGTTACGCAGAAGCACAAAAGCGTGGGCTCATTGCCACCTATGAAAAAACCGTTCAGAGCGCATTTAAAGATGTCGCTA
ACGCACTGGCGCGGCGGACCACGCTTGAAGAGCAACTGGATGCACAGAGCCAGTATGTTAAAGCTGAGCAACAAACGGTC
GATGTTGGCTTGCGTCGCTATCAGGCGGGTGTTGGTGATTACCTGACCGTGTTGACGGCGCAGCGCAGCTTGTGGAGCGC
ACAGCAGGAGCTGCTGGCACTGCAACTGACTGATTTTACAAACCGAATCACGCTCTGGCAGTCGCTGGGCGGCGGTATGT
CATCACTCAAGTAA

Upstream 100 bases:

>100_bases
CACGCTGACCGCTACATTACTGGCCATTTTCTTCGTTCCTCTGTTTTTTGTACTGGTGAAACGTTTGTTTGCCGGTAAAC
CGCGCCGTCAGGAGTAAGTT

Downstream 100 bases:

>100_bases
GGAATAATATGGCTAGAGTCTCTCTTTCATGGGCATTGATTCTTGGTCTTTTAGCCGGTATCGGCCCGATGTGTACCGAT
CTTTATTTGCCGGCTTTGCC

Product: putative outer membrane channel protein of an efflux system

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 457; Mature: 457

Protein sequence:

>457_residues
MLRRSLIFLVLLSAGCVSLDPHYSTPESPIPATLPGAQDQGKAISHDWQQVIHDPRLQQVVTIALNSNRDVQKAIADIDS
ARALYGQTNASLFPTVNAALSSTRSRSMANGTGTTAEADGTVSSYTLDLFGRNQSLSRAARETWLASEFTAQNTRLTLIA
EISTAWLTLAADNSNLALAKETMTSAENSLKIIQRQQQVGTAAVTDVSEAMSVYQQARASVASYQTQVMQDKNALNLLAG
TTLAENLLPGTLESLPEQMISLVPAGVSSDVLLRRPDIQEAEHNLKSANADIGAARANFFPTISLTASAGVGSDALSSLF
SHGMQIWSFAPSVTLSLFTGGSNLAQLRYAEAQKRGLIATYEKTVQSAFKDVANALARRTTLEEQLDAQSQYVKAEQQTV
DVGLRRYQAGVGDYLTVLTAQRSLWSAQQELLALQLTDFTNRITLWQSLGGGMSSLK

Sequences:

>Translated_457_residues
MLRRSLIFLVLLSAGCVSLDPHYSTPESPIPATLPGAQDQGKAISHDWQQVIHDPRLQQVVTIALNSNRDVQKAIADIDS
ARALYGQTNASLFPTVNAALSSTRSRSMANGTGTTAEADGTVSSYTLDLFGRNQSLSRAARETWLASEFTAQNTRLTLIA
EISTAWLTLAADNSNLALAKETMTSAENSLKIIQRQQQVGTAAVTDVSEAMSVYQQARASVASYQTQVMQDKNALNLLAG
TTLAENLLPGTLESLPEQMISLVPAGVSSDVLLRRPDIQEAEHNLKSANADIGAARANFFPTISLTASAGVGSDALSSLF
SHGMQIWSFAPSVTLSLFTGGSNLAQLRYAEAQKRGLIATYEKTVQSAFKDVANALARRTTLEEQLDAQSQYVKAEQQTV
DVGLRRYQAGVGDYLTVLTAQRSLWSAQQELLALQLTDFTNRITLWQSLGGGMSSLK
>Mature_457_residues
MLRRSLIFLVLLSAGCVSLDPHYSTPESPIPATLPGAQDQGKAISHDWQQVIHDPRLQQVVTIALNSNRDVQKAIADIDS
ARALYGQTNASLFPTVNAALSSTRSRSMANGTGTTAEADGTVSSYTLDLFGRNQSLSRAARETWLASEFTAQNTRLTLIA
EISTAWLTLAADNSNLALAKETMTSAENSLKIIQRQQQVGTAAVTDVSEAMSVYQQARASVASYQTQVMQDKNALNLLAG
TTLAENLLPGTLESLPEQMISLVPAGVSSDVLLRRPDIQEAEHNLKSANADIGAARANFFPTISLTASAGVGSDALSSLF
SHGMQIWSFAPSVTLSLFTGGSNLAQLRYAEAQKRGLIATYEKTVQSAFKDVANALARRTTLEEQLDAQSQYVKAEQQTV
DVGLRRYQAGVGDYLTVLTAQRSLWSAQQELLALQLTDFTNRITLWQSLGGGMSSLK

Specific function: The outer membrane component of an antibiotic efflux pump. Confers resistance to numerous structurally unrelated antibiotics such as carbenicillin, chloramphenicol, erythromycin, novobiocin, streptomycin and tetracycline. Is not involved in organic solven

COG id: COG1538

COG function: function code MU; Outer membrane protein

Gene ontology:

Cell location: Cell outer membrane; Lipid-anchor (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family [H]

Homologues:

Organism=Escherichia coli, GI1786785, Length=456, Percent_Identity=36.1842105263158, Blast_Score=267, Evalue=1e-72,
Organism=Escherichia coli, GI2367348, Length=421, Percent_Identity=23.9904988123515, Blast_Score=91, Evalue=1e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003423
- InterPro:   IPR010131 [H]

Pfam domain/function: PF02321 OEP [H]

EC number: NA

Molecular weight: Translated: 49175; Mature: 49175

Theoretical pI: Translated: 5.74; Mature: 5.74

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLRRSLIFLVLLSAGCVSLDPHYSTPESPIPATLPGAQDQGKAISHDWQQVIHDPRLQQV
CCHHHHHHHHHHHCCCEECCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCHHHHE
VTIALNSNRDVQKAIADIDSARALYGQTNASLFPTVNAALSSTRSRSMANGTGTTAEADG
EEEEECCCCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCC
TVSSYTLDLFGRNQSLSRAARETWLASEFTAQNTRLTLIAEISTAWLTLAADNSNLALAK
CCEEEEEEEECCCHHHHHHHHHHHHHHHHHCCCCEEEEEEEECEEEEEEEECCCCCEEHH
ETMTSAENSLKIIQRQQQVGTAAVTDVSEAMSVYQQARASVASYQTQVMQDKNALNLLAG
HHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHH
TTLAENLLPGTLESLPEQMISLVPAGVSSDVLLRRPDIQEAEHNLKSANADIGAARANFF
HHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCEEECCCHHHHHHHHHHCCCCCCCHHCCCC
PTISLTASAGVGSDALSSLFSHGMQIWSFAPSVTLSLFTGGSNLAQLRYAEAQKRGLIAT
CEEEEEECCCCCHHHHHHHHHCCHHHHHCCCCEEEEEEECCCCHHHHHHHHHHHCCCHHH
YEKTVQSAFKDVANALARRTTLEEQLDAQSQYVKAEQQTVDVGLRRYQAGVGDYLTVLTA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
QRSLWSAQQELLALQLTDFTNRITLWQSLGGGMSSLK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHCCC
>Mature Secondary Structure
MLRRSLIFLVLLSAGCVSLDPHYSTPESPIPATLPGAQDQGKAISHDWQQVIHDPRLQQV
CCHHHHHHHHHHHCCCEECCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCHHHHE
VTIALNSNRDVQKAIADIDSARALYGQTNASLFPTVNAALSSTRSRSMANGTGTTAEADG
EEEEECCCCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCC
TVSSYTLDLFGRNQSLSRAARETWLASEFTAQNTRLTLIAEISTAWLTLAADNSNLALAK
CCEEEEEEEECCCHHHHHHHHHHHHHHHHHCCCCEEEEEEEECEEEEEEEECCCCCEEHH
ETMTSAENSLKIIQRQQQVGTAAVTDVSEAMSVYQQARASVASYQTQVMQDKNALNLLAG
HHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHH
TTLAENLLPGTLESLPEQMISLVPAGVSSDVLLRRPDIQEAEHNLKSANADIGAARANFF
HHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCEEECCCHHHHHHHHHHCCCCCCCHHCCCC
PTISLTASAGVGSDALSSLFSHGMQIWSFAPSVTLSLFTGGSNLAQLRYAEAQKRGLIAT
CEEEEEECCCCCHHHHHHHHHCCHHHHHCCCCEEEEEEECCCCHHHHHHHHHHHCCCHHH
YEKTVQSAFKDVANALARRTTLEEQLDAQSQYVKAEQQTVDVGLRRYQAGVGDYLTVLTA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
QRSLWSAQQELLALQLTDFTNRITLWQSLGGGMSSLK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11160799 [H]