Click here to switch to the map view.

The map label for this gene is dmsD [H]

Identifier: 218551403

GI number: 218551403

Start: 4293377

End: 4294024

Strand: Direct

Name: dmsD [H]

Synonym: EFER_4184

Alternate gene names: 218551403

Gene position: 4293377-4294024 (Clockwise)

Preceding gene: 218551402

Following gene: 218551404

Centisome position: 93.56

GC content: 51.54

Gene sequence:

>648_bases
GTGAGTGGCCGGTGTCTGCCCGGCCACCTCTGCTTTCAGGAGTGTTTAATCATGCCTTCCCCAGCCGTACTGGTGCGTAT
TCTTGGTGCCCTGTTTTACTATTCTCCCACGCGTCCTGAAGTTCGGGCACTGTTTGACTGTCTGCCGACATTGGATGAGA
TATACGCCTGGCGCGATCCCCGCCAGGTGGCTGAATTATGCTCTGACTGGTCAATCCCGGATGAGGAGCAGCATCTCTGG
CAATTTTCTGTTCTTTTTGAAGGACAGGGTGAAATGCCAGCACCGCCCTGGGGTTCGGTATATCTCGAAAAAGATAATCT
GTTGATGGGTGACAGCACTGCCGAGTACCGGAAGTTCCTTCGTGATCAGGGAATGACGTTTGATTCCTGTATAAATGAAC
CGGAAGATCAGTTTGGCCTGATGCTGCTTGCCTGTAGCGCCTTGCTGGCAGAGGGGAAAGAACGTGCAGCTAATCAATTG
CTGGAAACGCATTTGCTGCCGTGGGGATATCGTTATCTGGAGTTATTACAGCGCAACCCTGTCAGTGCGTTTTACGCGAA
GTTGGCGCAGATTGCGACACTGTTTCTGCAGGATTATCAGCAGCAACAGGCACTAAATCCTCCAACCAAACGGCTCTTTC
TTGGATGA

Upstream 100 bases:

>100_bases
TGGGCAAGCTGTGCTGGTGATGACTGCACTGGTGGTTATTGCTGCTGAACTGGTTGGTCGGATCGGTTTCTACAACCTCT
GGACCATCCCTATGTAACCT

Downstream 100 bases:

>100_bases
GTAAGTCAGAAAAATATTATCAGGAGTTAATGTCTCATCGGTATGTTAGCCGACGTGGGCTATTTCGGGCCTTTGTCAGC
GCGGCACGCCCGGTAACAAC

Product: twin-argninine leader-binding protein for anaerobic dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 215; Mature: 214

Protein sequence:

>215_residues
MSGRCLPGHLCFQECLIMPSPAVLVRILGALFYYSPTRPEVRALFDCLPTLDEIYAWRDPRQVAELCSDWSIPDEEQHLW
QFSVLFEGQGEMPAPPWGSVYLEKDNLLMGDSTAEYRKFLRDQGMTFDSCINEPEDQFGLMLLACSALLAEGKERAANQL
LETHLLPWGYRYLELLQRNPVSAFYAKLAQIATLFLQDYQQQQALNPPTKRLFLG

Sequences:

>Translated_215_residues
MSGRCLPGHLCFQECLIMPSPAVLVRILGALFYYSPTRPEVRALFDCLPTLDEIYAWRDPRQVAELCSDWSIPDEEQHLW
QFSVLFEGQGEMPAPPWGSVYLEKDNLLMGDSTAEYRKFLRDQGMTFDSCINEPEDQFGLMLLACSALLAEGKERAANQL
LETHLLPWGYRYLELLQRNPVSAFYAKLAQIATLFLQDYQQQQALNPPTKRLFLG
>Mature_214_residues
SGRCLPGHLCFQECLIMPSPAVLVRILGALFYYSPTRPEVRALFDCLPTLDEIYAWRDPRQVAELCSDWSIPDEEQHLWQ
FSVLFEGQGEMPAPPWGSVYLEKDNLLMGDSTAEYRKFLRDQGMTFDSCINEPEDQFGLMLLACSALLAEGKERAANQLL
ETHLLPWGYRYLELLQRNPVSAFYAKLAQIATLFLQDYQQQQALNPPTKRLFLG

Specific function: Binds to the twin-arginine signal peptide of dmsA and torA. Could be required for the biogenesis of DMSO reductase rather than for the targeting of dmsA to the inner membrane [H]

COG id: COG3381

COG function: function code R; Uncharacterized component of anaerobic dehydrogenases

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein. Cytoplasm (By similarity). Note=Mainly cytoplasmic under aerobic conditions, and found in the inner membrane under anaerobic conditions (By similarity) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the torD/dmsD family. DmsD subfamily [H]

Homologues:

Organism=Escherichia coli, GI87081942, Length=193, Percent_Identity=36.2694300518135, Blast_Score=125, Evalue=3e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020945 [H]

Pfam domain/function: PF02613 Nitrate_red_del [H]

EC number: NA

Molecular weight: Translated: 24630; Mature: 24498

Theoretical pI: Translated: 4.49; Mature: 4.49

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.3 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
6.0 %Cys+Met (Translated Protein)
3.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSGRCLPGHLCFQECLIMPSPAVLVRILGALFYYSPTRPEVRALFDCLPTLDEIYAWRDP
CCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCH
RQVAELCSDWSIPDEEQHLWQFSVLFEGQGEMPAPPWGSVYLEKDNLLMGDSTAEYRKFL
HHHHHHHHCCCCCCCHHHHHHHHEEEECCCCCCCCCCCCEEEECCCEEECCCHHHHHHHH
RDQGMTFDSCINEPEDQFGLMLLACSALLAEGKERAANQLLETHLLPWGYRYLELLQRNP
HHCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCC
VSAFYAKLAQIATLFLQDYQQQQALNPPTKRLFLG
HHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCC
>Mature Secondary Structure 
SGRCLPGHLCFQECLIMPSPAVLVRILGALFYYSPTRPEVRALFDCLPTLDEIYAWRDP
CCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCH
RQVAELCSDWSIPDEEQHLWQFSVLFEGQGEMPAPPWGSVYLEKDNLLMGDSTAEYRKFL
HHHHHHHHCCCCCCCHHHHHHHHEEEECCCCCCCCCCCCEEEECCCEEECCCHHHHHHHH
RDQGMTFDSCINEPEDQFGLMLLACSALLAEGKERAANQLLETHLLPWGYRYLELLQRNP
HHCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCC
VSAFYAKLAQIATLFLQDYQQQQALNPPTKRLFLG
HHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]