Click here to switch to the map view.

The map label for this gene is xylB [H]

Identifier: 218550849

GI number: 218550849

Start: 3647383

End: 3648846

Strand: Reverse

Name: xylB [H]

Synonym: EFER_3565

Alternate gene names: 218550849

Gene position: 3648846-3647383 (Counterclockwise)

Preceding gene: 218550850

Following gene: 218550848

Centisome position: 79.52

GC content: 53.07

Gene sequence:

>1464_bases
ATGATCGCTATGTATATCGGGATAGATCTTGGTACATCGGGTGTAAAAGCTATTCTGCTCAATGAACAGGGTGAGGTTGT
CGCGTCGCATACAGAAAAACTTACCGTATCACGCCCCTATCCTCTCTGGTCAGAGCAAGATCCAGAACAGTGGTGGCAGG
CAACCGACCGTGCTGTAAAAGCATTGGGGCAGTTGCATTCACTACAGGGTGTTAAAGCGTTAGGTATTGCCGGGCAGATG
CATGGAGCAACGCTTCTTGATTCGCAAAATCAGATTCTGCGCCCGGCTATTTTGTGGAATGACGGTCGATGCGGTGAAGA
GTGTGCTTTGCTGGAGCAAAAAGTACCACAGTCTCGGGCTATCACCGGCAACCTGATGATGCCTGGCTTTACTGCGCCAA
AACTGCTTTGGGTTCAGCGTCACGAACCGGAGGTTTTCAGCCGGGTGGCAAAAGTGTTACTGCCGAAAGATTATCTGCGT
CTGCGTATGACGGGCGATTTTGCCAGCGATATGTCTGATGCCGCAGGAACGATGTGGCTGGATGTGGCGAAGCGTGACTG
GAGCGATGTCATGCTGGAGGCCTGTCAGTTAACCCGTGATCATATGCCTGCGCTTTACGAAGGCAGTGAAATCACCGGCA
CGTTATTACCGGAAGTTGCCCGTGCATGGGGAATGCCATCTGTACCTGTTGTTGCGGGTGGGGGCGATAACGCCGCAGGG
GCCGTCGGCGTGGGAATGATTGACGCAAACCAGGCGATGTTGTCGCTCGGAACATCTGGTGTGTACTTTGCTGTTAGCGA
AGGCTTTTTGAGCAAGCCGGAAAGCGCCGTGCATAGCTTTTGCCACGCATTGCCGGAACGCTGGCATTTAATGTCAGTGA
TGTTGAGTGCGGCATCATGTCTGGACTGGGCGGCGAAATTAACCGGTATGGAATCTGTTCCGGTACTGATTAACGCAGCA
CAACAGGCTGATGAAAAGGCCGATCCTGTCTGGTTCTTACCTTATCTTTCTGGCGAGCGCACGCCACACAATAATCCACA
GGCGAAGGGTGTTTTCTTTGGACTAACCCATCAGCATGGTCCGGCGGAGCTGGCAAAAGCAGTGCTTGAGGGAGTGGGAT
ATGCCCTGGCCGATGGTATGGATGTGGTCCACGCATGTGGTGTTAAACCGCAAAGCGTAACGTTAATTGGTGGTGGTGCG
CGTAGTGCGTACTGGCGTCAGATGCTGGCGGATATTAGTGGTCAGCAACTGGATTATCGTACAGGCGGTGATGTTGGTCC
GGCACTCGGCGCGGCCAGGTTGGCACAAATTGCCGTCGGCAAAGACAAGTCGCTGGCAGAATTGCTACCACAACTCCCAC
TGGAGCAAACCCATACCCCAGATGCTCAACGTCATGTGGCATATCAGCCACAACGTGACACTTTCCGTCGTCTCTATCAG
CAATTGCTGCCTCTTATGGGGTAA

Upstream 100 bases:

>100_bases
GGAAAGTCTGGTGAATCATTATTTGTTCGATAAATAATCGTTAACAAAGACAGTCCCTGAGCCCGGTAAGCGGTAGCGAT
ACCGGGCATTTTTGTAAGGA

Downstream 100 bases:

>100_bases
TAAATTCCCCTGTCTGTCCGGGCAGGGGAATTTATCCAATCTATATATTTTTTAAATCAATAAAAATTTAATATGAATGT
ATTCTGAAAATCATTTGTTA

Product: xylulokinase

Products: NA

Alternate protein names: Xylulokinase [H]

Number of amino acids: Translated: 487; Mature: 487

Protein sequence:

>487_residues
MIAMYIGIDLGTSGVKAILLNEQGEVVASHTEKLTVSRPYPLWSEQDPEQWWQATDRAVKALGQLHSLQGVKALGIAGQM
HGATLLDSQNQILRPAILWNDGRCGEECALLEQKVPQSRAITGNLMMPGFTAPKLLWVQRHEPEVFSRVAKVLLPKDYLR
LRMTGDFASDMSDAAGTMWLDVAKRDWSDVMLEACQLTRDHMPALYEGSEITGTLLPEVARAWGMPSVPVVAGGGDNAAG
AVGVGMIDANQAMLSLGTSGVYFAVSEGFLSKPESAVHSFCHALPERWHLMSVMLSAASCLDWAAKLTGMESVPVLINAA
QQADEKADPVWFLPYLSGERTPHNNPQAKGVFFGLTHQHGPAELAKAVLEGVGYALADGMDVVHACGVKPQSVTLIGGGA
RSAYWRQMLADISGQQLDYRTGGDVGPALGAARLAQIAVGKDKSLAELLPQLPLEQTHTPDAQRHVAYQPQRDTFRRLYQ
QLLPLMG

Sequences:

>Translated_487_residues
MIAMYIGIDLGTSGVKAILLNEQGEVVASHTEKLTVSRPYPLWSEQDPEQWWQATDRAVKALGQLHSLQGVKALGIAGQM
HGATLLDSQNQILRPAILWNDGRCGEECALLEQKVPQSRAITGNLMMPGFTAPKLLWVQRHEPEVFSRVAKVLLPKDYLR
LRMTGDFASDMSDAAGTMWLDVAKRDWSDVMLEACQLTRDHMPALYEGSEITGTLLPEVARAWGMPSVPVVAGGGDNAAG
AVGVGMIDANQAMLSLGTSGVYFAVSEGFLSKPESAVHSFCHALPERWHLMSVMLSAASCLDWAAKLTGMESVPVLINAA
QQADEKADPVWFLPYLSGERTPHNNPQAKGVFFGLTHQHGPAELAKAVLEGVGYALADGMDVVHACGVKPQSVTLIGGGA
RSAYWRQMLADISGQQLDYRTGGDVGPALGAARLAQIAVGKDKSLAELLPQLPLEQTHTPDAQRHVAYQPQRDTFRRLYQ
QLLPLMG
>Mature_487_residues
MIAMYIGIDLGTSGVKAILLNEQGEVVASHTEKLTVSRPYPLWSEQDPEQWWQATDRAVKALGQLHSLQGVKALGIAGQM
HGATLLDSQNQILRPAILWNDGRCGEECALLEQKVPQSRAITGNLMMPGFTAPKLLWVQRHEPEVFSRVAKVLLPKDYLR
LRMTGDFASDMSDAAGTMWLDVAKRDWSDVMLEACQLTRDHMPALYEGSEITGTLLPEVARAWGMPSVPVVAGGGDNAAG
AVGVGMIDANQAMLSLGTSGVYFAVSEGFLSKPESAVHSFCHALPERWHLMSVMLSAASCLDWAAKLTGMESVPVLINAA
QQADEKADPVWFLPYLSGERTPHNNPQAKGVFFGLTHQHGPAELAKAVLEGVGYALADGMDVVHACGVKPQSVTLIGGGA
RSAYWRQMLADISGQQLDYRTGGDVGPALGAARLAQIAVGKDKSLAELLPQLPLEQTHTPDAQRHVAYQPQRDTFRRLYQ
QLLPLMG

Specific function: Unknown

COG id: COG1070

COG function: function code G; Sugar (pentulose and hexulose) kinases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FGGY kinase family [H]

Homologues:

Organism=Homo sapiens, GI42794763, Length=439, Percent_Identity=23.0068337129841, Blast_Score=106, Evalue=6e-23,
Organism=Homo sapiens, GI4504007, Length=438, Percent_Identity=23.0593607305936, Blast_Score=104, Evalue=1e-22,
Organism=Homo sapiens, GI189409120, Length=438, Percent_Identity=23.0593607305936, Blast_Score=104, Evalue=2e-22,
Organism=Homo sapiens, GI41393575, Length=431, Percent_Identity=22.969837587007, Blast_Score=99, Evalue=8e-21,
Organism=Homo sapiens, GI164663828, Length=535, Percent_Identity=24.4859813084112, Blast_Score=91, Evalue=2e-18,
Organism=Homo sapiens, GI88196792, Length=511, Percent_Identity=23.2876712328767, Blast_Score=90, Evalue=4e-18,
Organism=Homo sapiens, GI164663830, Length=558, Percent_Identity=23.2974910394265, Blast_Score=81, Evalue=2e-15,
Organism=Escherichia coli, GI1789987, Length=483, Percent_Identity=88.4057971014493, Blast_Score=864, Evalue=0.0,
Organism=Escherichia coli, GI1790005, Length=496, Percent_Identity=24.5967741935484, Blast_Score=128, Evalue=7e-31,
Organism=Escherichia coli, GI1787789, Length=519, Percent_Identity=24.6628131021195, Blast_Score=123, Evalue=3e-29,
Organism=Escherichia coli, GI1790361, Length=498, Percent_Identity=23.8955823293173, Blast_Score=122, Evalue=4e-29,
Organism=Escherichia coli, GI1789168, Length=419, Percent_Identity=26.491646778043, Blast_Score=111, Evalue=9e-26,
Organism=Caenorhabditis elegans, GI17535599, Length=449, Percent_Identity=23.8307349665924, Blast_Score=99, Evalue=5e-21,
Organism=Drosophila melanogaster, GI24655555, Length=475, Percent_Identity=22.5263157894737, Blast_Score=86, Evalue=5e-17,
Organism=Drosophila melanogaster, GI24655560, Length=475, Percent_Identity=22.5263157894737, Blast_Score=86, Evalue=5e-17,
Organism=Drosophila melanogaster, GI24655570, Length=475, Percent_Identity=22.5263157894737, Blast_Score=86, Evalue=5e-17,
Organism=Drosophila melanogaster, GI24655574, Length=475, Percent_Identity=22.5263157894737, Blast_Score=86, Evalue=5e-17,
Organism=Drosophila melanogaster, GI24655565, Length=475, Percent_Identity=22.5263157894737, Blast_Score=86, Evalue=5e-17,
Organism=Drosophila melanogaster, GI19920476, Length=501, Percent_Identity=23.9520958083832, Blast_Score=73, Evalue=4e-13,
Organism=Drosophila melanogaster, GI21356607, Length=318, Percent_Identity=25.7861635220126, Blast_Score=67, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000577
- InterPro:   IPR018485
- InterPro:   IPR018483
- InterPro:   IPR018484
- InterPro:   IPR006000 [H]

Pfam domain/function: PF02782 FGGY_C; PF00370 FGGY_N [H]

EC number: =2.7.1.17 [H]

Molecular weight: Translated: 52688; Mature: 52688

Theoretical pI: Translated: 6.02; Mature: 6.02

Prosite motif: PS00933 FGGY_KINASES_1 ; PS00445 FGGY_KINASES_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIAMYIGIDLGTSGVKAILLNEQGEVVASHTEKLTVSRPYPLWSEQDPEQWWQATDRAVK
CEEEEEEEEECCCCCEEEEECCCCCEEECCCCEEEECCCCCCCCCCCHHHHHHHHHHHHH
ALGQLHSLQGVKALGIAGQMHGATLLDSQNQILRPAILWNDGRCGEECALLEQKVPQSRA
HHHHHHHHCCCHHHCCCCCCCCCEEECCCCCCCCCEEEECCCCCCHHHHHHHHHCCCCCC
ITGNLMMPGFTAPKLLWVQRHEPEVFSRVAKVLLPKDYLRLRMTGDFASDMSDAAGTMWL
CCCCEECCCCCCCEEEEEECCCHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHCCCEEE
DVAKRDWSDVMLEACQLTRDHMPALYEGSEITGTLLPEVARAWGMPSVPVVAGGGDNAAG
HHHHCCHHHHHHHHHHHHHHCCCCEECCCCCCHHHHHHHHHHCCCCCCCEEECCCCCCCC
AVGVGMIDANQAMLSLGTSGVYFAVSEGFLSKPESAVHSFCHALPERWHLMSVMLSAASC
EEEEEEEECCHHHHHCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
LDWAAKLTGMESVPVLINAAQQADEKADPVWFLPYLSGERTPHNNPQAKGVFFGLTHQHG
HHHHHHHCCCCCCHHHHHHHHHCCCCCCCEEEEECCCCCCCCCCCCCCCEEEEEECCCCC
PAELAKAVLEGVGYALADGMDVVHACGVKPQSVTLIGGGARSAYWRQMLADISGQQLDYR
HHHHHHHHHHHCCHHHHCCHHHHHHCCCCCCEEEEEECCCHHHHHHHHHHHCCCCEEECC
TGGDVGPALGAARLAQIAVGKDKSLAELLPQLPLEQTHTPDAQRHVAYQPQRDTFRRLYQ
CCCCCCHHHHHHHHHHHHCCCCCHHHHHHHCCCCCCCCCCCHHHCCCCCCCHHHHHHHHH
QLLPLMG
HHHHCCC
>Mature Secondary Structure
MIAMYIGIDLGTSGVKAILLNEQGEVVASHTEKLTVSRPYPLWSEQDPEQWWQATDRAVK
CEEEEEEEEECCCCCEEEEECCCCCEEECCCCEEEECCCCCCCCCCCHHHHHHHHHHHHH
ALGQLHSLQGVKALGIAGQMHGATLLDSQNQILRPAILWNDGRCGEECALLEQKVPQSRA
HHHHHHHHCCCHHHCCCCCCCCCEEECCCCCCCCCEEEECCCCCCHHHHHHHHHCCCCCC
ITGNLMMPGFTAPKLLWVQRHEPEVFSRVAKVLLPKDYLRLRMTGDFASDMSDAAGTMWL
CCCCEECCCCCCCEEEEEECCCHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHCCCEEE
DVAKRDWSDVMLEACQLTRDHMPALYEGSEITGTLLPEVARAWGMPSVPVVAGGGDNAAG
HHHHCCHHHHHHHHHHHHHHCCCCEECCCCCCHHHHHHHHHHCCCCCCCEEECCCCCCCC
AVGVGMIDANQAMLSLGTSGVYFAVSEGFLSKPESAVHSFCHALPERWHLMSVMLSAASC
EEEEEEEECCHHHHHCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
LDWAAKLTGMESVPVLINAAQQADEKADPVWFLPYLSGERTPHNNPQAKGVFFGLTHQHG
HHHHHHHCCCCCCHHHHHHHHHCCCCCCCEEEEECCCCCCCCCCCCCCCEEEEEECCCCC
PAELAKAVLEGVGYALADGMDVVHACGVKPQSVTLIGGGARSAYWRQMLADISGQQLDYR
HHHHHHHHHHHCCHHHHCCHHHHHHCCCCCCEEEEEECCCHHHHHHHHHHHCCCCEEECC
TGGDVGPALGAARLAQIAVGKDKSLAELLPQLPLEQTHTPDAQRHVAYQPQRDTFRRLYQ
CCCCCCHHHHHHHHHHHHCCCCCHHHHHHHCCCCCCCCCCCHHHCCCCCCCHHHHHHHHH
QLLPLMG
HHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 6320721; 8041620; 9278503 [H]