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The map label for this gene is kdsC [H]

Identifier: 218550481

GI number: 218550481

Start: 3261697

End: 3262263

Strand: Direct

Name: kdsC [H]

Synonym: EFER_3175

Alternate gene names: 218550481

Gene position: 3261697-3262263 (Clockwise)

Preceding gene: 218550480

Following gene: 218550482

Centisome position: 71.08

GC content: 51.5

Gene sequence:

>567_bases
ATGAGTACAGCAGGTACGTCGCTTGCGACCTGTTACGGCCCCGTAAGTACTGAGGTCATGGCAAAAGCAGAGAAAATCCA
GTTGCTGATTCTGGATGTTGATGGCGTATTGTCGGATGGCCTGATTTATATGGGCAATAACGGCGAAGAGCTGAAGGCCT
TCAACGTGCGGGATGGCTATGGCATTCGTTGTGCGCTCACTTCAGGAATCGAAGTCGCCATTATTACCGGACGAAAGGCT
AAACTTGTAGAGGATCGGTGTGCCACGTTGAAGATCAACCACCTGTATCAGGGGCAGTCCGATAAGTTAATTGCGTTTGC
TGATCTTCTGGCAAAACTGGCGATTGCACCAGAGAACGTCGCTTACATTGGTGACGATCTGATCGACTGGCCGGTTATGG
AAAAAGTGGGCTTCAGCGTCGCTGTCGCCGATGCACACCCGTTATTGTTACCACGCGCAGACTACGTGACCAGAATTGCA
GGCGGACGCGGTGCCGTTCGTGAAGTCTGCGATCTGTTATTACTCGCACAGGGCAAGCTTGATGAGGCCAAAGGGCAATC
GATATGA

Upstream 100 bases:

>100_bases
TCACTTCCGTACTGGTTGCTGATGGCGACCATTTACTCGGTGTGTTACATATGCATGATCTGCTGCGAGCAGGCGTAGTT
TAGAAATCAAGGATAACCAA

Downstream 100 bases:

>100_bases
GTAAAGCCAGACGTTGGGTTATCATTCTGCTGTCGTTGGCCGTACTGGTGATGATTGGTATCAACCTGGCCGATAATGAA
GATACTGCTCAGGTGGTGGT

Product: 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase

Products: NA

Alternate protein names: KDO 8-P phosphatase [H]

Number of amino acids: Translated: 188; Mature: 187

Protein sequence:

>188_residues
MSTAGTSLATCYGPVSTEVMAKAEKIQLLILDVDGVLSDGLIYMGNNGEELKAFNVRDGYGIRCALTSGIEVAIITGRKA
KLVEDRCATLKINHLYQGQSDKLIAFADLLAKLAIAPENVAYIGDDLIDWPVMEKVGFSVAVADAHPLLLPRADYVTRIA
GGRGAVREVCDLLLLAQGKLDEAKGQSI

Sequences:

>Translated_188_residues
MSTAGTSLATCYGPVSTEVMAKAEKIQLLILDVDGVLSDGLIYMGNNGEELKAFNVRDGYGIRCALTSGIEVAIITGRKA
KLVEDRCATLKINHLYQGQSDKLIAFADLLAKLAIAPENVAYIGDDLIDWPVMEKVGFSVAVADAHPLLLPRADYVTRIA
GGRGAVREVCDLLLLAQGKLDEAKGQSI
>Mature_187_residues
STAGTSLATCYGPVSTEVMAKAEKIQLLILDVDGVLSDGLIYMGNNGEELKAFNVRDGYGIRCALTSGIEVAIITGRKAK
LVEDRCATLKINHLYQGQSDKLIAFADLLAKLAIAPENVAYIGDDLIDWPVMEKVGFSVAVADAHPLLLPRADYVTRIAG
GRGAVREVCDLLLLAQGKLDEAKGQSI

Specific function: Catalyzes the hydrolysis of KDO 8-P to KDO and inorganic phosphate [H]

COG id: COG1778

COG function: function code R; Low specificity phosphatase (HAD superfamily)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the kdsC family [H]

Homologues:

Organism=Homo sapiens, GI8923900, Length=163, Percent_Identity=30.6748466257669, Blast_Score=84, Evalue=1e-16,
Organism=Escherichia coli, GI2367202, Length=188, Percent_Identity=91.4893617021277, Blast_Score=349, Evalue=8e-98,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023214
- InterPro:   IPR013200
- InterPro:   IPR006549
- InterPro:   IPR010023 [H]

Pfam domain/function: PF08282 Hydrolase_3 [H]

EC number: =3.1.3.45 [H]

Molecular weight: Translated: 20049; Mature: 19918

Theoretical pI: Translated: 4.84; Mature: 4.84

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTAGTSLATCYGPVSTEVMAKAEKIQLLILDVDGVLSDGLIYMGNNGEELKAFNVRDGY
CCCCCCCEEEEECCCCHHHHHHHCEEEEEEEECCCCCCCCEEEECCCCCEEEEEECCCCC
GIRCALTSGIEVAIITGRKAKLVEDRCATLKINHLYQGQSDKLIAFADLLAKLAIAPENV
CEEEEEECCCEEEEEECCCCHHHHCCCCEEEEEEEECCCCCCCHHHHHHHHHHHCCCCCE
AYIGDDLIDWPVMEKVGFSVAVADAHPLLLPRADYVTRIAGGRGAVREVCDLLLLAQGKL
EEECCCCCCCHHHHHCCCEEEEECCCCEEEECCHHHHEECCCCCHHHHHHHHHHHCCCCC
DEAKGQSI
CCCCCCCC
>Mature Secondary Structure 
STAGTSLATCYGPVSTEVMAKAEKIQLLILDVDGVLSDGLIYMGNNGEELKAFNVRDGY
CCCCCCEEEEECCCCHHHHHHHCEEEEEEEECCCCCCCCEEEECCCCCEEEEEECCCCC
GIRCALTSGIEVAIITGRKAKLVEDRCATLKINHLYQGQSDKLIAFADLLAKLAIAPENV
CEEEEEECCCEEEEEECCCCHHHHCCCCEEEEEEEECCCCCCCHHHHHHHHHHHCCCCCE
AYIGDDLIDWPVMEKVGFSVAVADAHPLLLPRADYVTRIAGGRGAVREVCDLLLLAQGKL
EEECCCCCCCHHHHHCCCEEEEECCCCEEEECCHHHHEECCCCCHHHHHHHHHHHCCCCC
DEAKGQSI
CCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]