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The map label for this gene is hofC [H]

Identifier: 218547561

GI number: 218547561

Start: 136377

End: 137612

Strand: Reverse

Name: hofC [H]

Synonym: EFER_0126

Alternate gene names: 218547561

Gene position: 137612-136377 (Counterclockwise)

Preceding gene: 218547562

Following gene: 218547559

Centisome position: 3.0

GC content: 48.95

Gene sequence:

>1236_bases
TTGAAGAGCTCATTCGCGTGTTGGGAATACCTCATGGCCACTAAGCAACTCTGGTGCTGGCAAGGGATTGACAGCGATGG
CCACGCACAAGAAGGCGTATTGTGGGCACAAAACCGTGCCGGACTGCTGCTTAATTTGCAGCAGTTGCGGATCACGCCCC
TAAGCATGAGAAAGATAAACGTGCAGAAGGCCCACTGGAGTTCACGAAGAAGCGCAGAAGTTATCCATCAGTTAGCAACG
CTGCTAAAAGCTGGACTAACACTTTCTGAAGGGTTAGCGCTACTTGCCGGGCAGCATCCCAGTAAACAATGGCAGGCACT
GTTACAGACACTGGCCCATGAACTGGAGCAAGGCAATGCGCTTTCCCGTGCATTAACGCAATGGTCAGAGGTATTTCCCC
CACTTTACCAGGCGATGATCCGTACAGGTGAATTAACCGGAAAGCTGGATGAATGTTGTTTTGAACTGGCCCGCCAGCAA
AAAGCACAGCATTTGCTGGCAGAGAAAGTGAAAAAAGCATTGCGCTATCCGCTGATCATTTTAACGCTGGCTATTGTTGT
GGTTGTAGCAATGCTGCATTTTGTGTTGCCTGAATTTGCCGCTATTTATAAAACCTTCAACACGCCCTTGCCTGCACTGA
CACAAGGTGTCATGGCTACAGCTGATTTTATCAGTCAGTGGGGAGGGTTAATAATGGCCTTAATCGTCCTGCTGGCTATC
GCAAATCGGTTAATCAGTCGCAACACAGAGTGGCTTATTATTCGCCAGCGTTTGCTGCTTCGCTGTCCTGTCGTTGGTGC
GCTGATACGCGGGCAAAAGCTCACACAGATTTTTACTATTCTCGCGTTAACACAAAGTGTTGGGATCTCGTTTTTGCAGG
GGTTGGAGAGTGTCAGAGAAACCATCAGTTGCCCATACTGGTCACAACGGTTAAGGCAAATGCAGCAGGAAATCAGCACG
GGGCATCCCATCTGGCTGGCATTAAAAAACGCCGAAGAGTTCAGTCCACTATGTATGCAACTGGTGAGAACAGGTGAAGC
GTCTGGTTCGCTGGACTCCATGTTGCACAATCTTGCTCAGCACCACAGCGAAAATACATTCAGTCTTGCAGACAGCCTGG
CTGCTCTTCTGGAGCCAGCATTACTGGTGGTGACAGGGATCATTATCGGAACGTTGGTAGTGGCAATGTATTTACCAATA
TTCCATCTTGGAGATGCAATGAGTGGAATGGGATAA

Upstream 100 bases:

>100_bases
GGTAGTGGTGTGGCAGAACTGGAAACACACGCACAACAGGAAGGTATCCAGCCGCTTTTTGCTAATGGCTGCCAGGCTGT
TGAGCAAGGGTTAACCACGT

Downstream 100 bases:

>100_bases
CGCTGGCGTGAGTTTGCACGCCAGCGTTGCGTGGTTACAGGCTATTGAAAATACGGTTTTCTTGTTCCTGAACGCGAATA
AACGTTGTGCGTTTGGTCAA

Product: type IV pilin biogenesis protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 411; Mature: 411

Protein sequence:

>411_residues
MKSSFACWEYLMATKQLWCWQGIDSDGHAQEGVLWAQNRAGLLLNLQQLRITPLSMRKINVQKAHWSSRRSAEVIHQLAT
LLKAGLTLSEGLALLAGQHPSKQWQALLQTLAHELEQGNALSRALTQWSEVFPPLYQAMIRTGELTGKLDECCFELARQQ
KAQHLLAEKVKKALRYPLIILTLAIVVVVAMLHFVLPEFAAIYKTFNTPLPALTQGVMATADFISQWGGLIMALIVLLAI
ANRLISRNTEWLIIRQRLLLRCPVVGALIRGQKLTQIFTILALTQSVGISFLQGLESVRETISCPYWSQRLRQMQQEIST
GHPIWLALKNAEEFSPLCMQLVRTGEASGSLDSMLHNLAQHHSENTFSLADSLAALLEPALLVVTGIIIGTLVVAMYLPI
FHLGDAMSGMG

Sequences:

>Translated_411_residues
MKSSFACWEYLMATKQLWCWQGIDSDGHAQEGVLWAQNRAGLLLNLQQLRITPLSMRKINVQKAHWSSRRSAEVIHQLAT
LLKAGLTLSEGLALLAGQHPSKQWQALLQTLAHELEQGNALSRALTQWSEVFPPLYQAMIRTGELTGKLDECCFELARQQ
KAQHLLAEKVKKALRYPLIILTLAIVVVVAMLHFVLPEFAAIYKTFNTPLPALTQGVMATADFISQWGGLIMALIVLLAI
ANRLISRNTEWLIIRQRLLLRCPVVGALIRGQKLTQIFTILALTQSVGISFLQGLESVRETISCPYWSQRLRQMQQEIST
GHPIWLALKNAEEFSPLCMQLVRTGEASGSLDSMLHNLAQHHSENTFSLADSLAALLEPALLVVTGIIIGTLVVAMYLPI
FHLGDAMSGMG
>Mature_411_residues
MKSSFACWEYLMATKQLWCWQGIDSDGHAQEGVLWAQNRAGLLLNLQQLRITPLSMRKINVQKAHWSSRRSAEVIHQLAT
LLKAGLTLSEGLALLAGQHPSKQWQALLQTLAHELEQGNALSRALTQWSEVFPPLYQAMIRTGELTGKLDECCFELARQQ
KAQHLLAEKVKKALRYPLIILTLAIVVVVAMLHFVLPEFAAIYKTFNTPLPALTQGVMATADFISQWGGLIMALIVLLAI
ANRLISRNTEWLIIRQRLLLRCPVVGALIRGQKLTQIFTILALTQSVGISFLQGLESVRETISCPYWSQRLRQMQQEIST
GHPIWLALKNAEEFSPLCMQLVRTGEASGSLDSMLHNLAQHHSENTFSLADSLAALLEPALLVVTGIIIGTLVVAMYLPI
FHLGDAMSGMG

Specific function: Unknown

COG id: COG1459

COG function: function code NU; Type II secretory pathway, component PulF

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GSP F family [H]

Homologues:

Organism=Escherichia coli, GI1786295, Length=400, Percent_Identity=75.25, Blast_Score=586, Evalue=1e-169,
Organism=Escherichia coli, GI1789724, Length=403, Percent_Identity=25.3101736972705, Blast_Score=131, Evalue=8e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003004
- InterPro:   IPR018076
- InterPro:   IPR001992 [H]

Pfam domain/function: PF00482 GSPII_F [H]

EC number: NA

Molecular weight: Translated: 45670; Mature: 45670

Theoretical pI: Translated: 8.68; Mature: 8.68

Prosite motif: PS00874 T2SP_F

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKSSFACWEYLMATKQLWCWQGIDSDGHAQEGVLWAQNRAGLLLNLQQLRITPLSMRKIN
CCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEECCCCCHHEEHHHHHCCHHHHHHHH
VQKAHWSSRRSAEVIHQLATLLKAGLTLSEGLALLAGQHPSKQWQALLQTLAHELEQGNA
HHHHHHCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCH
LSRALTQWSEVFPPLYQAMIRTGELTGKLDECCFELARQQKAQHLLAEKVKKALRYPLII
HHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LTLAIVVVVAMLHFVLPEFAAIYKTFNTPLPALTQGVMATADFISQWGGLIMALIVLLAI
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ANRLISRNTEWLIIRQRLLLRCPVVGALIRGQKLTQIFTILALTQSVGISFLQGLESVRE
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TISCPYWSQRLRQMQQEISTGHPIWLALKNAEEFSPLCMQLVRTGEASGSLDSMLHNLAQ
HHCCCHHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHH
HHSENTFSLADSLAALLEPALLVVTGIIIGTLVVAMYLPIFHLGDAMSGMG
HCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MKSSFACWEYLMATKQLWCWQGIDSDGHAQEGVLWAQNRAGLLLNLQQLRITPLSMRKIN
CCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEECCCCCHHEEHHHHHCCHHHHHHHH
VQKAHWSSRRSAEVIHQLATLLKAGLTLSEGLALLAGQHPSKQWQALLQTLAHELEQGNA
HHHHHHCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCH
LSRALTQWSEVFPPLYQAMIRTGELTGKLDECCFELARQQKAQHLLAEKVKKALRYPLII
HHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LTLAIVVVVAMLHFVLPEFAAIYKTFNTPLPALTQGVMATADFISQWGGLIMALIVLLAI
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ANRLISRNTEWLIIRQRLLLRCPVVGALIRGQKLTQIFTILALTQSVGISFLQGLESVRE
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TISCPYWSQRLRQMQQEISTGHPIWLALKNAEEFSPLCMQLVRTGEASGSLDSMLHNLAQ
HHCCCHHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHH
HHSENTFSLADSLAALLEPALLVVTGIIIGTLVVAMYLPIFHLGDAMSGMG
HCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7959070; 8202364; 9278503; 2904262 [H]