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The map label for this gene is trpD [H]

Identifier: 218234472

GI number: 218234472

Start: 1254311

End: 1255336

Strand: Direct

Name: trpD [H]

Synonym: BCB4264_A1293

Alternate gene names: 218234472

Gene position: 1254311-1255336 (Clockwise)

Preceding gene: 218234059

Following gene: 218232195

Centisome position: 23.15

GC content: 36.45

Gene sequence:

>1026_bases
ATGAATAACTATCTTCGTAAATTAGTGGAGGGTCAACATTTAACAGAAGAGGAAATGTATAAAGCAGGACTACTTTTATT
AAGTGAAAACATATTAGAAAGTGAAATTGCAGCTTTCTTAGTCTTACTGAAAGCGAAAGGTGAAACTGCAGAAGAAATAT
ACGGTCTCGTTCGAGCTCTTCGCGAAAAGGCATTGCCGTTTTCGAACCATATACAAGGAGCAATGGACAATTGCGGGACG
GGTGGTGACGGTGCTCAAACGTTTAATATTAGCACAACATCAGCATTCGTACTGGCAGGAGCAGGTGTAAAGGTTGCAAA
ACATGGTAATCGTGCTGTTTCTAGTAAAACAGGAAGTGCAGACTTATTAGAAGAACTAGGTGTAAATATTAGTAGTACGC
CAAACGAAATTGATTATTTACTAGAGCATGTGGGCATTGCATTTTTATTTGCACCAGTGATGCATCCAGCACTAAGGCGC
ATTATGAAAATAAGAAAAGAGTTAAACGTGCCGACGATCTTTAATTTAATTGGTCCTTTAACAAATCCAGTGAATTTAGA
AACACAATTTGTCGGTATTTATAAACGAGATATGTTATTACCAGTTGCAGAAGTATTACAAAAGTTAGGCCGGAAACAAG
CGCTTGTCGTAAATGGAAGTGGTTTTTTAGATGAAGCGTCATTACAAGGGGAAAATCACGTAGTCCTTTTAAAAGATAAT
GAAATAGTAGAAATGAGTATTGATCCAGAAAAGTATGGTTTTTCAAGAGTGAAAAATGAAGAAATTAGAGGGGGGAATTC
AAAAGAAAATGCAAAGATTACGCTTGAAGTATTGAGCGGAGAAAAGAGTGTTTATCGTGATACAGTTTTATTAAATGCAG
GTCTAGCTCTTTTCGCAAATGGAAAAACGGAAACGATTGAAGAAGGAATTAAACTCGCGGCACATAGCATTGACTCTGGA
AAAGCATTAACCAAATTAAACTTATTAATTGCAGCAAGCAATGAAAAATTAGAAAGGGTGAACTAA

Upstream 100 bases:

>100_bases
CGCTCTTCGGATTACAGTTTCATCCAGAATCAATCGCAACAGAAGAAGGCGGAAAGTTAATACGTGCCTTTTTAACAGAA
ATAAAAGAGGAGGAAAGAGT

Downstream 100 bases:

>100_bases
AGTGGGGACGATTTTAGATGAAATTGTAGAACAGAAGCAAAGGGAAGTTGCGGAGTTGTATGAAATATATACACCAGTAA
AAACAAAAAGAAAGACACAT

Product: anthranilate phosphoribosyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 341; Mature: 341

Protein sequence:

>341_residues
MNNYLRKLVEGQHLTEEEMYKAGLLLLSENILESEIAAFLVLLKAKGETAEEIYGLVRALREKALPFSNHIQGAMDNCGT
GGDGAQTFNISTTSAFVLAGAGVKVAKHGNRAVSSKTGSADLLEELGVNISSTPNEIDYLLEHVGIAFLFAPVMHPALRR
IMKIRKELNVPTIFNLIGPLTNPVNLETQFVGIYKRDMLLPVAEVLQKLGRKQALVVNGSGFLDEASLQGENHVVLLKDN
EIVEMSIDPEKYGFSRVKNEEIRGGNSKENAKITLEVLSGEKSVYRDTVLLNAGLALFANGKTETIEEGIKLAAHSIDSG
KALTKLNLLIAASNEKLERVN

Sequences:

>Translated_341_residues
MNNYLRKLVEGQHLTEEEMYKAGLLLLSENILESEIAAFLVLLKAKGETAEEIYGLVRALREKALPFSNHIQGAMDNCGT
GGDGAQTFNISTTSAFVLAGAGVKVAKHGNRAVSSKTGSADLLEELGVNISSTPNEIDYLLEHVGIAFLFAPVMHPALRR
IMKIRKELNVPTIFNLIGPLTNPVNLETQFVGIYKRDMLLPVAEVLQKLGRKQALVVNGSGFLDEASLQGENHVVLLKDN
EIVEMSIDPEKYGFSRVKNEEIRGGNSKENAKITLEVLSGEKSVYRDTVLLNAGLALFANGKTETIEEGIKLAAHSIDSG
KALTKLNLLIAASNEKLERVN
>Mature_341_residues
MNNYLRKLVEGQHLTEEEMYKAGLLLLSENILESEIAAFLVLLKAKGETAEEIYGLVRALREKALPFSNHIQGAMDNCGT
GGDGAQTFNISTTSAFVLAGAGVKVAKHGNRAVSSKTGSADLLEELGVNISSTPNEIDYLLEHVGIAFLFAPVMHPALRR
IMKIRKELNVPTIFNLIGPLTNPVNLETQFVGIYKRDMLLPVAEVLQKLGRKQALVVNGSGFLDEASLQGENHVVLLKDN
EIVEMSIDPEKYGFSRVKNEEIRGGNSKENAKITLEVLSGEKSVYRDTVLLNAGLALFANGKTETIEEGIKLAAHSIDSG
KALTKLNLLIAASNEKLERVN

Specific function: Tryptophan biosynthesis; first step. Tryptophan biosynthesis; second step. [C]

COG id: COG0547

COG function: function code E; Anthranilate phosphoribosyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the anthranilate phosphoribosyltransferase family [H]

Homologues:

Organism=Escherichia coli, GI1787517, Length=277, Percent_Identity=40.072202166065, Blast_Score=193, Evalue=2e-50,
Organism=Saccharomyces cerevisiae, GI6320561, Length=275, Percent_Identity=32.7272727272727, Blast_Score=122, Evalue=6e-29,

Paralogues:

None

Copy number: 945 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 900 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005940
- InterPro:   IPR000312
- InterPro:   IPR017459
- InterPro:   IPR020072 [H]

Pfam domain/function: PF02885 Glycos_trans_3N; PF00591 Glycos_transf_3 [H]

EC number: =2.4.2.18 [H]

Molecular weight: Translated: 37108; Mature: 37108

Theoretical pI: Translated: 5.95; Mature: 5.95

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNNYLRKLVEGQHLTEEEMYKAGLLLLSENILESEIAAFLVLLKAKGETAEEIYGLVRAL
CCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHH
REKALPFSNHIQGAMDNCGTGGDGAQTFNISTTSAFVLAGAGVKVAKHGNRAVSSKTGSA
HHHCCCCHHHHCHHHHCCCCCCCCCEEEEECCCCEEEEECCCEEEEECCCCHHCCCCCCH
DLLEELGVNISSTPNEIDYLLEHVGIAFLFAPVMHPALRRIMKIRKELNVPTIFNLIGPL
HHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCC
TNPVNLETQFVGIYKRDMLLPVAEVLQKLGRKQALVVNGSGFLDEASLQGENHVVLLKDN
CCCCCCCEEEEEHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCCEEEEECC
EIVEMSIDPEKYGFSRVKNEEIRGGNSKENAKITLEVLSGEKSVYRDTVLLNAGLALFAN
CEEEEEECCHHHCHHHCCCHHHCCCCCCCCCEEEEEEECCCHHHHHHHHHEECCEEEEEC
GKTETIEEGIKLAAHSIDSGKALTKLNLLIAASNEKLERVN
CCHHHHHHHHHHHHHCCCCCCCEEEEEEEEEECCCHHHCCC
>Mature Secondary Structure
MNNYLRKLVEGQHLTEEEMYKAGLLLLSENILESEIAAFLVLLKAKGETAEEIYGLVRAL
CCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHH
REKALPFSNHIQGAMDNCGTGGDGAQTFNISTTSAFVLAGAGVKVAKHGNRAVSSKTGSA
HHHCCCCHHHHCHHHHCCCCCCCCCEEEEECCCCEEEEECCCEEEEECCCCHHCCCCCCH
DLLEELGVNISSTPNEIDYLLEHVGIAFLFAPVMHPALRRIMKIRKELNVPTIFNLIGPL
HHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCC
TNPVNLETQFVGIYKRDMLLPVAEVLQKLGRKQALVVNGSGFLDEASLQGENHVVLLKDN
CCCCCCCEEEEEHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCCEEEEECC
EIVEMSIDPEKYGFSRVKNEEIRGGNSKENAKITLEVLSGEKSVYRDTVLLNAGLALFAN
CEEEEEECCHHHCHHHCCCHHHCCCCCCCCCEEEEEEECCCHHHHHHHHHEECCEEEEEC
GKTETIEEGIKLAAHSIDSGKALTKLNLLIAASNEKLERVN
CCHHHHHHHHHHHHHCCCCCCCEEEEEEEEEECCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA