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The map label for this gene is trpGD [H]

Identifier: 218234059

GI number: 218234059

Start: 1253727

End: 1254314

Strand: Direct

Name: trpGD [H]

Synonym: BCB4264_A1292

Alternate gene names: 218234059

Gene position: 1253727-1254314 (Clockwise)

Preceding gene: 218235640

Following gene: 218234472

Centisome position: 23.14

GC content: 40.82

Gene sequence:

>588_bases
ATGATTGTACTTATCGATAATTACGATTCGTTCACATATAACTTGTATCAACTGTTAGGCGAACATGAAGAAGAAATTGT
AGTTGTAAGAAATGATGAAATAACGATAGAACAGTTAGAAGAGGTGAATCCAAGAGGAATTGTACTTTCACCAGGACCAG
GAAAACCAGAGGATGCTGGCATTTGTATCGACGTCATCCGTCATTTTTATAAGAACGTTCCCATATTAGGGATTTGTCTT
GGCCACCAAGCGATCATAGCTGCATTTGGAGGAGACATTGTTAGAGCAGAATGTATTAAACATGGAAAAACATCGCGTGT
GAAACATAACGGAACGTCAATCTTTTCATACGCTACCCAGCCGCTAACGGCAATGCGCTATCATTCCCTTGTTGCAGAGC
AAACGAGCTTGCCAGAGTGTTTTGACATATTAGCGACAGCGATGGACGACGGAGAGATAATGGCAGTCCGTCACAATTAT
TATCCGCTCTTCGGATTACAGTTTCATCCAGAATCAATCGCAACAGAAGAAGGCGGAAAGTTAATACGTGCCTTTTTAAC
AGAAATAAAAGAGGAGGAAAGAGTATGA

Upstream 100 bases:

>100_bases
CATATGTTCAGGCAGGAGCAGGAGTCGTTTACGATTCAGATCCAGTAGCTGAATATGAAGAAACATTAAATAAAGCGAGA
GCGCTTTTGGAGGTAATGAA

Downstream 100 bases:

>100_bases
ATAACTATCTTCGTAAATTAGTGGAGGGTCAACATTTAACAGAAGAGGAAATGTATAAAGCAGGACTACTTTTATTAAGT
GAAAACATATTAGAAAGTGA

Product: anthranilate synthase component II

Products: NA

Alternate protein names: Glutamine amidotransferase; Anthranilate phosphoribosyltransferase [H]

Number of amino acids: Translated: 195; Mature: 195

Protein sequence:

>195_residues
MIVLIDNYDSFTYNLYQLLGEHEEEIVVVRNDEITIEQLEEVNPRGIVLSPGPGKPEDAGICIDVIRHFYKNVPILGICL
GHQAIIAAFGGDIVRAECIKHGKTSRVKHNGTSIFSYATQPLTAMRYHSLVAEQTSLPECFDILATAMDDGEIMAVRHNY
YPLFGLQFHPESIATEEGGKLIRAFLTEIKEEERV

Sequences:

>Translated_195_residues
MIVLIDNYDSFTYNLYQLLGEHEEEIVVVRNDEITIEQLEEVNPRGIVLSPGPGKPEDAGICIDVIRHFYKNVPILGICL
GHQAIIAAFGGDIVRAECIKHGKTSRVKHNGTSIFSYATQPLTAMRYHSLVAEQTSLPECFDILATAMDDGEIMAVRHNY
YPLFGLQFHPESIATEEGGKLIRAFLTEIKEEERV
>Mature_195_residues
MIVLIDNYDSFTYNLYQLLGEHEEEIVVVRNDEITIEQLEEVNPRGIVLSPGPGKPEDAGICIDVIRHFYKNVPILGICL
GHQAIIAAFGGDIVRAECIKHGKTSRVKHNGTSIFSYATQPLTAMRYHSLVAEQTSLPECFDILATAMDDGEIMAVRHNY
YPLFGLQFHPESIATEEGGKLIRAFLTEIKEEERV

Specific function: Catalyzes The Biosynthesis Of 4-Amino-4-Deoxychorismate (Adc) From Chorismate And Glutamine. [C]

COG id: COG0512

COG function: function code EH; Anthranilate/para-aminobenzoate synthases component II

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 glutamine amidotransferase type-1 domain [H]

Homologues:

Organism=Homo sapiens, GI18105007, Length=185, Percent_Identity=28.6486486486486, Blast_Score=70, Evalue=2e-12,
Organism=Escherichia coli, GI1789760, Length=186, Percent_Identity=53.2258064516129, Blast_Score=212, Evalue=1e-56,
Organism=Escherichia coli, GI1787517, Length=194, Percent_Identity=41.2371134020619, Blast_Score=150, Evalue=8e-38,
Organism=Escherichia coli, GI1786215, Length=141, Percent_Identity=29.0780141843972, Blast_Score=74, Evalue=7e-15,
Organism=Saccharomyces cerevisiae, GI6322638, Length=187, Percent_Identity=45.9893048128342, Blast_Score=182, Evalue=4e-47,
Organism=Saccharomyces cerevisiae, GI6324361, Length=208, Percent_Identity=32.2115384615385, Blast_Score=89, Evalue=5e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005940
- InterPro:   IPR006220
- InterPro:   IPR001317
- InterPro:   IPR011702
- InterPro:   IPR017926
- InterPro:   IPR000991
- InterPro:   IPR000312
- InterPro:   IPR017459
- InterPro:   IPR020072
- InterPro:   IPR006221 [H]

Pfam domain/function: PF00117 GATase; PF02885 Glycos_trans_3N; PF00591 Glycos_transf_3 [H]

EC number: =4.1.3.27; =2.4.2.18 [H]

Molecular weight: Translated: 21861; Mature: 21861

Theoretical pI: Translated: 4.72; Mature: 4.72

Prosite motif: PS00442 GATASE_TYPE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIVLIDNYDSFTYNLYQLLGEHEEEIVVVRNDEITIEQLEEVNPRGIVLSPGPGKPEDAG
CEEEEECCCCHHHHHHHHHCCCCCCEEEEECCCEEHHHHHCCCCCEEEECCCCCCCCCCC
ICIDVIRHFYKNVPILGICLGHQAIIAAFGGDIVRAECIKHGKTSRVKHNGTSIFSYATQ
HHHHHHHHHHCCCCEEEEEECHHHHHHHHCCCHHHHHHHHCCCCCEEECCCCEEEEECCC
PLTAMRYHSLVAEQTSLPECFDILATAMDDGEIMAVRHNYYPLFGLQFHPESIATEEGGK
CHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCEEEEEECCCEEEEEEECCHHHCCCCCHH
LIRAFLTEIKEEERV
HHHHHHHHHHHHCCC
>Mature Secondary Structure
MIVLIDNYDSFTYNLYQLLGEHEEEIVVVRNDEITIEQLEEVNPRGIVLSPGPGKPEDAG
CEEEEECCCCHHHHHHHHHCCCCCCEEEEECCCEEHHHHHCCCCCEEEECCCCCCCCCCC
ICIDVIRHFYKNVPILGICLGHQAIIAAFGGDIVRAECIKHGKTSRVKHNGTSIFSYATQ
HHHHHHHHHHCCCCEEEEEECHHHHHHHHCCCHHHHHHHHCCCCCEEECCCCEEEEECCC
PLTAMRYHSLVAEQTSLPECFDILATAMDDGEIMAVRHNYYPLFGLQFHPESIATEEGGK
CHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCEEEEEECCCEEEEEEECCHHHCCCCCHH
LIRAFLTEIKEEERV
HHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7685830; 10360571; 7556082 [H]