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The map label for this gene is argE [C]

Identifier: 213692755

GI number: 213692755

Start: 2060321

End: 2061688

Strand: Reverse

Name: argE [C]

Synonym: Blon_1889

Alternate gene names: 213692755

Gene position: 2061688-2060321 (Counterclockwise)

Preceding gene: 213692760

Following gene: 213692754

Centisome position: 72.78

GC content: 63.01

Gene sequence:

>1368_bases
ATGGCAACGTTCACCGCTGACGAGATTCGTTCGCGCGTCGAAACCGATTGGAACCGCATCGTCAAGGTGCTGGCCGAAAA
GGTCGCGCTGCAGTCGATCTCCGCCAAGGGCATCACCGCCGAACATATGAAGCGCTCCGCTGAATTCGTGGCAGACGAAC
TGCGCCTCGTGGGTGTGGATGCCAAGGTGGTCCAGGCTTCCAATGCCGATGGCACTCCGGGCGCATGGGAGGTCATCGGC
TCGCATATCGTTTCTCCGGACGCCCCCACCGTGCTGCTCTACGCCCATCACGATGTGCAGCCTGTTCCGGACCCGGCCGA
ATGGGACACCGACCCGTTCGTGGCCACCGAAATCGACGGCCGCCTTTACGGCCGTGGCTCCGCCGATGACGGCGGCGGCA
TCGCTATCCACTCCGGTGCGCTGAAGGCCTTGGGCGACGACCTCAACGTCAATATCAAAGTGTTCATCGAAGGCGAAGAG
GAGATGGGTTCGCCAAGCTTCATTCCCTTCATCGAGGCTCACCGCGACGAATTCGCCGCTGACGTGATTATCGTGGCTGA
TTCCGGCAACTGGTCGGCGGACATTCCTTCTTTGACCACCTCGCTGCGCGGTAACACCTGTGTGGACGTGACCGTGCAGG
GCCTTGAGCATCCGGTGCACTCCGGCCAGTACGGCGGCCCGATTCTCGACTCCAATACGTTGGCCGCCATGCTCATCGCT
TCCATGTATGACGAGAACGGCGATCTGGCCGTACCCGGCGTGGCCGCGGAAGAGCCGATCGGCGGTTTGCAGCACGACCT
TGACGAAACCACTGTGCGCGAGGATTCCGGCGTGGTGGCCGGTTACGAGTTCGCCGGCACCGGTTCGCTGGCCTCACGCC
TGTGGACCAAGCCGTCCGTGACCGTGATCGGCTTCGACGCCCACCCGGTCGAGGGATCCTTCAACGTGATCGCCCCGGAG
ACCCGCTTCCGTTTGTCGCTGCGCACCGCGCCCACCCAGCGCCCTGAAGAAGCGCAGGAAGCACTGGCTGCATTCTTCGA
ATCCCACGCGCCGTTCGGTGCCAAGGTCACTGTCGAACGCGGCGAAAACGGCATGGGCTGGGCCATGGACCCGACTGCCG
TGGCCACCAAGGACGCGCTGGAAGCCATGACCGAGGCTTTCGGCGTTGAGCCCATCAACAAGGGCGAAGGCGGCTCCATT
CCGTTCATCCCCGAACTGCAGCGCATTTTCCCCAACGCTCAGGTGCTGGTCACCGGTCCCGAAGACCCGAAGGCCAACGC
CCACAGCCCCAATGAGTCCATCTCCCTGCCCGGCCTCAAGAACAACGTGATCACCGAGGCTTTGCTGCTGGACAAGCTCG
GCAAGTAG

Upstream 100 bases:

>100_bases
CCATGTCATGCTTTGAGGTTACGGTGACGTTCAGACACTTGTACACTGGCGCAGTCATTGCAATGACGCCGCTCACGCAC
ATATATAAAGGAGGATCATC

Downstream 100 bases:

>100_bases
CCGAACCGTATCGGTAATGGTAGCGAGCCGCCGTCCGGTAGGTCACAGATGTGGCTATTGCCTTTGACGGCGGCTTGCTT
TATAGTCGGGGAGTTGACAC

Product: hypothetical protein

Products: Acetate; Ornithine [C]

Alternate protein names: Peptidase; M20/M25/M40 Family Peptidase; Peptidase Family; ArgE/DapE/Acy1 Family Protein; Succinyl-Diaminopimelate Desuccinylase; Peptidase Dimerization Domain Protein; Beta-Ala-His Dipeptidase; Succinyl-Diaminopimelate Desuccinylase Protein; Zinc Metallopeptidase; N-Acyl-L-Amino Acid Amidohydrolase; Peptidase Dimerisation Domain Protein; Peptidase Dimerisation Domain-Containing Protein; Peptidase Or Deacetlylase Family Protein; Acetylornithine Deacetylase ArgE; Low Quality Protein; M20 Family Peptidase; Metallopeptidase; Thiol Dipeptidase; Peptidase Dimerisation

Number of amino acids: Translated: 455; Mature: 454

Protein sequence:

>455_residues
MATFTADEIRSRVETDWNRIVKVLAEKVALQSISAKGITAEHMKRSAEFVADELRLVGVDAKVVQASNADGTPGAWEVIG
SHIVSPDAPTVLLYAHHDVQPVPDPAEWDTDPFVATEIDGRLYGRGSADDGGGIAIHSGALKALGDDLNVNIKVFIEGEE
EMGSPSFIPFIEAHRDEFAADVIIVADSGNWSADIPSLTTSLRGNTCVDVTVQGLEHPVHSGQYGGPILDSNTLAAMLIA
SMYDENGDLAVPGVAAEEPIGGLQHDLDETTVREDSGVVAGYEFAGTGSLASRLWTKPSVTVIGFDAHPVEGSFNVIAPE
TRFRLSLRTAPTQRPEEAQEALAAFFESHAPFGAKVTVERGENGMGWAMDPTAVATKDALEAMTEAFGVEPINKGEGGSI
PFIPELQRIFPNAQVLVTGPEDPKANAHSPNESISLPGLKNNVITEALLLDKLGK

Sequences:

>Translated_455_residues
MATFTADEIRSRVETDWNRIVKVLAEKVALQSISAKGITAEHMKRSAEFVADELRLVGVDAKVVQASNADGTPGAWEVIG
SHIVSPDAPTVLLYAHHDVQPVPDPAEWDTDPFVATEIDGRLYGRGSADDGGGIAIHSGALKALGDDLNVNIKVFIEGEE
EMGSPSFIPFIEAHRDEFAADVIIVADSGNWSADIPSLTTSLRGNTCVDVTVQGLEHPVHSGQYGGPILDSNTLAAMLIA
SMYDENGDLAVPGVAAEEPIGGLQHDLDETTVREDSGVVAGYEFAGTGSLASRLWTKPSVTVIGFDAHPVEGSFNVIAPE
TRFRLSLRTAPTQRPEEAQEALAAFFESHAPFGAKVTVERGENGMGWAMDPTAVATKDALEAMTEAFGVEPINKGEGGSI
PFIPELQRIFPNAQVLVTGPEDPKANAHSPNESISLPGLKNNVITEALLLDKLGK
>Mature_454_residues
ATFTADEIRSRVETDWNRIVKVLAEKVALQSISAKGITAEHMKRSAEFVADELRLVGVDAKVVQASNADGTPGAWEVIGS
HIVSPDAPTVLLYAHHDVQPVPDPAEWDTDPFVATEIDGRLYGRGSADDGGGIAIHSGALKALGDDLNVNIKVFIEGEEE
MGSPSFIPFIEAHRDEFAADVIIVADSGNWSADIPSLTTSLRGNTCVDVTVQGLEHPVHSGQYGGPILDSNTLAAMLIAS
MYDENGDLAVPGVAAEEPIGGLQHDLDETTVREDSGVVAGYEFAGTGSLASRLWTKPSVTVIGFDAHPVEGSFNVIAPET
RFRLSLRTAPTQRPEEAQEALAAFFESHAPFGAKVTVERGENGMGWAMDPTAVATKDALEAMTEAFGVEPINKGEGGSIP
FIPELQRIFPNAQVLVTGPEDPKANAHSPNESISLPGLKNNVITEALLLDKLGK

Specific function: Displays A Broad Specificity And Can Also Deacylate Substrates Such As Acetylarginine, Acetylhistidine Or Acetylglutamate Semialdehyde. [C]

COG id: COG0624

COG function: function code E; Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI271398239, Length=464, Percent_Identity=30.8189655172414, Blast_Score=165, Evalue=8e-41,
Organism=Homo sapiens, GI21071039, Length=462, Percent_Identity=28.3549783549784, Blast_Score=147, Evalue=2e-35,
Organism=Homo sapiens, GI271398277, Length=307, Percent_Identity=29.6416938110749, Blast_Score=99, Evalue=6e-21,
Organism=Caenorhabditis elegans, GI193211059, Length=459, Percent_Identity=28.9760348583878, Blast_Score=151, Evalue=5e-37,
Organism=Caenorhabditis elegans, GI17563146, Length=473, Percent_Identity=27.6955602536998, Blast_Score=146, Evalue=2e-35,
Organism=Saccharomyces cerevisiae, GI6319758, Length=390, Percent_Identity=27.6923076923077, Blast_Score=119, Evalue=1e-27,
Organism=Saccharomyces cerevisiae, GI6321159, Length=388, Percent_Identity=28.6082474226804, Blast_Score=117, Evalue=5e-27,
Organism=Drosophila melanogaster, GI24585880, Length=437, Percent_Identity=31.350114416476, Blast_Score=164, Evalue=2e-40,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 3.5.1.16 [C]

Molecular weight: Translated: 48301; Mature: 48170

Theoretical pI: Translated: 4.26; Mature: 4.26

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATFTADEIRSRVETDWNRIVKVLAEKVALQSISAKGITAEHMKRSAEFVADELRLVGVD
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCEEEEECC
AKVVQASNADGTPGAWEVIGSHIVSPDAPTVLLYAHHDVQPVPDPAEWDTDPFVATEIDG
CEEEEECCCCCCCHHHHHHHHHCCCCCCCEEEEEEECCCCCCCCCCCCCCCCEEEEEECC
RLYGRGSADDGGGIAIHSGALKALGDDLNVNIKVFIEGEEEMGSPSFIPFIEAHRDEFAA
EEEECCCCCCCCCEEEECCCHHHCCCCCCEEEEEEEECHHHCCCCCCCHHHHHHCCCCCE
DVIIVADSGNWSADIPSLTTSLRGNTCVDVTVQGLEHPVHSGQYGGPILDSNTLAAMLIA
EEEEEECCCCCCCCCCHHHHHCCCCEEEEEEEECCCCCCCCCCCCCCCCCCCHHHHHHHH
SMYDENGDLAVPGVAAEEPIGGLQHDLDETTVREDSGVVAGYEFAGTGSLASRLWTKPSV
HHHCCCCCEECCCCCCCCCCCCHHHCCCHHHEECCCCEEEEEEECCCCHHHHHHCCCCCE
TVIGFDAHPVEGSFNVIAPETRFRLSLRTAPTQRPEEAQEALAAFFESHAPFGAKVTVER
EEEECCCCCCCCCCEEECCCCEEEEEEECCCCCCHHHHHHHHHHHHHHCCCCCEEEEEEC
GENGMGWAMDPTAVATKDALEAMTEAFGVEPINKGEGGSIPFIPELQRIFPNAQVLVTGP
CCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHCCCCEEEEECC
EDPKANAHSPNESISLPGLKNNVITEALLLDKLGK
CCCCCCCCCCCCCEECCCCCCHHHHHHHHHHHHCC
>Mature Secondary Structure 
ATFTADEIRSRVETDWNRIVKVLAEKVALQSISAKGITAEHMKRSAEFVADELRLVGVD
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCEEEEECC
AKVVQASNADGTPGAWEVIGSHIVSPDAPTVLLYAHHDVQPVPDPAEWDTDPFVATEIDG
CEEEEECCCCCCCHHHHHHHHHCCCCCCCEEEEEEECCCCCCCCCCCCCCCCEEEEEECC
RLYGRGSADDGGGIAIHSGALKALGDDLNVNIKVFIEGEEEMGSPSFIPFIEAHRDEFAA
EEEECCCCCCCCCEEEECCCHHHCCCCCCEEEEEEEECHHHCCCCCCCHHHHHHCCCCCE
DVIIVADSGNWSADIPSLTTSLRGNTCVDVTVQGLEHPVHSGQYGGPILDSNTLAAMLIA
EEEEEECCCCCCCCCCHHHHHCCCCEEEEEEEECCCCCCCCCCCCCCCCCCCHHHHHHHH
SMYDENGDLAVPGVAAEEPIGGLQHDLDETTVREDSGVVAGYEFAGTGSLASRLWTKPSV
HHHCCCCCEECCCCCCCCCCCCHHHCCCHHHEECCCCEEEEEEECCCCHHHHHHCCCCCE
TVIGFDAHPVEGSFNVIAPETRFRLSLRTAPTQRPEEAQEALAAFFESHAPFGAKVTVER
EEEECCCCCCCCCCEEECCCCEEEEEEECCCCCCHHHHHHHHHHHHHHCCCCCEEEEEEC
GENGMGWAMDPTAVATKDALEAMTEAFGVEPINKGEGGSIPFIPELQRIFPNAQVLVTGP
CCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHCCCCEEEEECC
EDPKANAHSPNESISLPGLKNNVITEALLLDKLGK
CCCCCCCCCCCCCEECCCCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: Glutathione. [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: N2-Acetyl-L-ornithine; H2O [C]

Specific reaction: N2-Acetyl-L-ornithine + H2O --> Acetate + Ornithine [C]

General reaction: Carboxylic acid amide hydrolysis [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA