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The map label for this gene is fkbP [H]

Identifier: 213692644

GI number: 213692644

Start: 1953395

End: 1953802

Strand: Reverse

Name: fkbP [H]

Synonym: Blon_1777

Alternate gene names: 213692644

Gene position: 1953802-1953395 (Counterclockwise)

Preceding gene: 213692645

Following gene: 213692643

Centisome position: 68.97

GC content: 64.22

Gene sequence:

>408_bases
ATGGCAGATCAGATGCCTCAGGTGAACGCCGAATACGGCACCACGCCCGTTATCGAGTTCCCGACGCCCGAAGCCCCGAA
GGGCCTCAAGGTTGTGGAGCTGACCGAGGGCGACGGCCCTATCGTGCGTCGCGGCGACACCGTCACCGTGAACTATCACG
GCGTGGTGTGGGGTAAGGACACCCCATTCGACTCCAGCTTCGACCGTCATCAGCCCGCCAGCTTCGGCATCGGCGTGGGA
CAGGTCATCAAGGGCTGGGACCAGACCGTGCCGGGCCATAACGTGGGTTCGCGTCTGGTGGTTTCCATTCCGCCGGAATA
CGGCTACGGTTCCCGCGGCATCCCGCAGGCCGGCATCGGCGGCGAGGACACGCTGGTGTTCGTCATCGACATCATTTCCA
CCCGCTGA

Upstream 100 bases:

>100_bases
CGTATACGGCCGGCGTGTCGTATCGCACAGGGATGAAGGACTACCGCCGATTCGCCGATGGTGCTAAGGTAGGGCGCATT
GTGTCTTTGAAGGAGGACTA

Downstream 100 bases:

>100_bases
CCACAGGTCAGCACATGACGAACGCCGGGGTCATAGCCGGCGTTTTGTCATAAATAACGAAGATTGTTTCAGCATCGACA
ACGGTTCAGGAGGACGATAT

Product: peptidylprolyl isomerase, FKBP-type

Products: NA

Alternate protein names: Peptidyl-prolyl cis-trans isomerase; PPIase; Rotamase [H]

Number of amino acids: Translated: 135; Mature: 134

Protein sequence:

>135_residues
MADQMPQVNAEYGTTPVIEFPTPEAPKGLKVVELTEGDGPIVRRGDTVTVNYHGVVWGKDTPFDSSFDRHQPASFGIGVG
QVIKGWDQTVPGHNVGSRLVVSIPPEYGYGSRGIPQAGIGGEDTLVFVIDIISTR

Sequences:

>Translated_135_residues
MADQMPQVNAEYGTTPVIEFPTPEAPKGLKVVELTEGDGPIVRRGDTVTVNYHGVVWGKDTPFDSSFDRHQPASFGIGVG
QVIKGWDQTVPGHNVGSRLVVSIPPEYGYGSRGIPQAGIGGEDTLVFVIDIISTR
>Mature_134_residues
ADQMPQVNAEYGTTPVIEFPTPEAPKGLKVVELTEGDGPIVRRGDTVTVNYHGVVWGKDTPFDSSFDRHQPASFGIGVGQ
VIKGWDQTVPGHNVGSRLVVSIPPEYGYGSRGIPQAGIGGEDTLVFVIDIISTR

Specific function: PPIases accelerate the folding of proteins [H]

COG id: COG0545

COG function: function code O; FKBP-type peptidyl-prolyl cis-trans isomerases 1

Gene ontology:

Cell location: Periplasmic Protein [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PPIase FKBP-type domain [H]

Homologues:

Organism=Homo sapiens, GI206725530, Length=91, Percent_Identity=43.956043956044, Blast_Score=72, Evalue=1e-13,
Organism=Homo sapiens, GI17149844, Length=91, Percent_Identity=43.956043956044, Blast_Score=72, Evalue=1e-13,
Organism=Homo sapiens, GI17149842, Length=91, Percent_Identity=43.956043956044, Blast_Score=72, Evalue=1e-13,
Organism=Homo sapiens, GI4503729, Length=114, Percent_Identity=40.3508771929825, Blast_Score=69, Evalue=2e-12,
Organism=Homo sapiens, GI17149836, Length=108, Percent_Identity=38.8888888888889, Blast_Score=67, Evalue=4e-12,
Organism=Homo sapiens, GI4503725, Length=108, Percent_Identity=38.8888888888889, Blast_Score=67, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI17540882, Length=91, Percent_Identity=40.6593406593407, Blast_Score=70, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI71993519, Length=100, Percent_Identity=41, Blast_Score=64, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6320727, Length=91, Percent_Identity=42.8571428571429, Blast_Score=73, Evalue=1e-14,
Organism=Saccharomyces cerevisiae, GI6324194, Length=106, Percent_Identity=41.5094339622642, Blast_Score=72, Evalue=2e-14,
Organism=Saccharomyces cerevisiae, GI6323566, Length=111, Percent_Identity=34.2342342342342, Blast_Score=61, Evalue=5e-11,
Organism=Drosophila melanogaster, GI281363946, Length=96, Percent_Identity=41.6666666666667, Blast_Score=82, Evalue=1e-16,
Organism=Drosophila melanogaster, GI17352457, Length=96, Percent_Identity=41.6666666666667, Blast_Score=82, Evalue=1e-16,
Organism=Drosophila melanogaster, GI24647110, Length=120, Percent_Identity=36.6666666666667, Blast_Score=75, Evalue=9e-15,
Organism=Drosophila melanogaster, GI24655568, Length=107, Percent_Identity=42.0560747663551, Blast_Score=74, Evalue=4e-14,

Paralogues:

None

Copy number: 200 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001179 [H]

Pfam domain/function: PF00254 FKBP_C [H]

EC number: =5.2.1.8 [H]

Molecular weight: Translated: 14448; Mature: 14317

Theoretical pI: Translated: 4.64; Mature: 4.64

Prosite motif: PS50059 FKBP_PPIASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
0.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MADQMPQVNAEYGTTPVIEFPTPEAPKGLKVVELTEGDGPIVRRGDTVTVNYHGVVWGKD
CCCCCCCCCCCCCCCCEEECCCCCCCCCCEEEEEECCCCCEEECCCEEEEEEEEEEECCC
TPFDSSFDRHQPASFGIGVGQVIKGWDQTVPGHNVGSRLVVSIPPEYGYGSRGIPQAGIG
CCCCCCCCCCCCCCCCCCHHHHHCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCC
GEDTLVFVIDIISTR
CCCEEEEEEEEECCC
>Mature Secondary Structure 
ADQMPQVNAEYGTTPVIEFPTPEAPKGLKVVELTEGDGPIVRRGDTVTVNYHGVVWGKD
CCCCCCCCCCCCCCCEEECCCCCCCCCCEEEEEECCCCCEEECCCEEEEEEEEEEECCC
TPFDSSFDRHQPASFGIGVGQVIKGWDQTVPGHNVGSRLVVSIPPEYGYGSRGIPQAGIG
CCCCCCCCCCCCCCCCCCHHHHHCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCC
GEDTLVFVIDIISTR
CCCEEEEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1381710 [H]