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The map label for this gene is sdaA [H]

Identifier: 213692645

GI number: 213692645

Start: 1953944

End: 1955404

Strand: Reverse

Name: sdaA [H]

Synonym: Blon_1778

Alternate gene names: 213692645

Gene position: 1955404-1953944 (Counterclockwise)

Preceding gene: 213692646

Following gene: 213692644

Centisome position: 69.03

GC content: 61.33

Gene sequence:

>1461_bases
ATGTTCAGTGTGCTTGACATGTTCACCATCGGCGTCGGACCTTCATCCTCGCACACTGTAGGCCCGATGGTCGCGGCACA
TGCCTTCGCCTCCTCGTTGCAGGCCGACCATTTGGTCGATCGCACCGCACGTGTCAAAATCACGCTTTACGGTTCTCTGG
CGCTGACCGGTCTCGGCCACGGCACCGATCGCGCCGCAATGGCCGGGCTCGAAGGCAATCTGCCGGCCACCGTGGATACC
GACCACATGATGCACATCCGCGAGACCTGCGCGTTGGACGATACTCTGAACCTTGCCGGCCTCAGACGCATCCATTTCGA
CTACGACCGCGACGTGGTGTTCGAACAATGGAAGCGCATGGCCGCGCACCCCAATGGCATGCGATTCCAGGCTTTCGACG
CCGCCGCAAGCTTGGTCGACGAACAGGTCTGGTATTCCATCGGCGGCGGATTCGTGCGCAAAGGCGCTCCCGAAGACCCG
ATGATCGGCATTCATGAACGCCCTCCGGAAGGCACCTCCTTTGCCGACGCGGACGAATCATCATCCACTGATTTCGGCGT
CGAGGCACCCTACCCGTTCTCGTCATGCACCGAACTGGTGTCGTTGTGCCGGGAACATCATCTCAGCATCGCCGAACTTG
TATGGGCCAACGAAACCGCTTCACGCTCGGGCGCCCAGGTCCGATCCGATATTGATGCCATCTGGCGTGTTATGCGCGCC
TGTGTGGACCACGGATGCACCTCGGCGGAACCCACATTGCCCGGTGGCCTTGACGTACCCCGCCGCGCGCCGAAAATGTA
TCGGCGTCTCGCCTTGAATTCCGATGTGCTGCGCCGCGACAGCCGGCGCAAGGACGCCGTGCTCGAATCCTCGGACGCCG
CATGGGTGGACCTGTTCGCCTTGGCCGTTTCTGAGGAGAATGCCGGAGGCGGGCGCATCGTAACCGCTCCGACCAACGGT
TCCGCCGGCATCATTCCCGCCGTGCTTCACTATTATTGGCATTTCGTGGACAACGCCAATGAACAGGGCGTGGTCACGTT
TCTGCTGACCGCCGGTGCCATCGGATACCTGTTCAAACGCAACGCCTCAATTTCCGGTGCGGAAGTCGGTTGCCAGGGCG
AAGTCGGCTCGGCCTGTTCGATGGCGGCGGCCGGACTTGCCGCAGTCATGGGCGGCACGCCGGAACAGGTGGAGAATGCT
GCTGAGATCGGCATCGAACACAACTTGGGCCTGACTTGCGATCCGGTGGGCGGACTGGTGCAGATTCCATGCATCGAACG
CAACGCCATGGCCGCCAACACCGCCATCAACGCCGTGCGTATGGCCATGCTCGGCGACGGCTCACACATCGTGACCCTCG
ATCAGGCCATCGAAACCATGAAGCAGACCGGTGAAGACATGATGGCCAAATACAAGGAGACCTCCAAGGGCGGGCTTGCC
GTCAATGTCGTCGAATGCTGA

Upstream 100 bases:

>100_bases
AGGCGAAAGCGATTCCGGGCGCTAGGCTGGAATACGATATCGTGATGGCGTGACGCCTGGCAACACCGGCATGCCGAACC
AGCAGGGGAGAAGGAGCCAA

Downstream 100 bases:

>100_bases
TTGACATGTCTGGTATTCACCAGCATGATGATCGGAATTGACGTATACGGCCGGCGTGTCGTATCGCACAGGGATGAAGG
ACTACCGCCGATTCGCCGAT

Product: L-serine dehydratase 1

Products: NA

Alternate protein names: SDH; L-serine deaminase; L-SD [H]

Number of amino acids: Translated: 486; Mature: 486

Protein sequence:

>486_residues
MFSVLDMFTIGVGPSSSHTVGPMVAAHAFASSLQADHLVDRTARVKITLYGSLALTGLGHGTDRAAMAGLEGNLPATVDT
DHMMHIRETCALDDTLNLAGLRRIHFDYDRDVVFEQWKRMAAHPNGMRFQAFDAAASLVDEQVWYSIGGGFVRKGAPEDP
MIGIHERPPEGTSFADADESSSTDFGVEAPYPFSSCTELVSLCREHHLSIAELVWANETASRSGAQVRSDIDAIWRVMRA
CVDHGCTSAEPTLPGGLDVPRRAPKMYRRLALNSDVLRRDSRRKDAVLESSDAAWVDLFALAVSEENAGGGRIVTAPTNG
SAGIIPAVLHYYWHFVDNANEQGVVTFLLTAGAIGYLFKRNASISGAEVGCQGEVGSACSMAAAGLAAVMGGTPEQVENA
AEIGIEHNLGLTCDPVGGLVQIPCIERNAMAANTAINAVRMAMLGDGSHIVTLDQAIETMKQTGEDMMAKYKETSKGGLA
VNVVEC

Sequences:

>Translated_486_residues
MFSVLDMFTIGVGPSSSHTVGPMVAAHAFASSLQADHLVDRTARVKITLYGSLALTGLGHGTDRAAMAGLEGNLPATVDT
DHMMHIRETCALDDTLNLAGLRRIHFDYDRDVVFEQWKRMAAHPNGMRFQAFDAAASLVDEQVWYSIGGGFVRKGAPEDP
MIGIHERPPEGTSFADADESSSTDFGVEAPYPFSSCTELVSLCREHHLSIAELVWANETASRSGAQVRSDIDAIWRVMRA
CVDHGCTSAEPTLPGGLDVPRRAPKMYRRLALNSDVLRRDSRRKDAVLESSDAAWVDLFALAVSEENAGGGRIVTAPTNG
SAGIIPAVLHYYWHFVDNANEQGVVTFLLTAGAIGYLFKRNASISGAEVGCQGEVGSACSMAAAGLAAVMGGTPEQVENA
AEIGIEHNLGLTCDPVGGLVQIPCIERNAMAANTAINAVRMAMLGDGSHIVTLDQAIETMKQTGEDMMAKYKETSKGGLA
VNVVEC
>Mature_486_residues
MFSVLDMFTIGVGPSSSHTVGPMVAAHAFASSLQADHLVDRTARVKITLYGSLALTGLGHGTDRAAMAGLEGNLPATVDT
DHMMHIRETCALDDTLNLAGLRRIHFDYDRDVVFEQWKRMAAHPNGMRFQAFDAAASLVDEQVWYSIGGGFVRKGAPEDP
MIGIHERPPEGTSFADADESSSTDFGVEAPYPFSSCTELVSLCREHHLSIAELVWANETASRSGAQVRSDIDAIWRVMRA
CVDHGCTSAEPTLPGGLDVPRRAPKMYRRLALNSDVLRRDSRRKDAVLESSDAAWVDLFALAVSEENAGGGRIVTAPTNG
SAGIIPAVLHYYWHFVDNANEQGVVTFLLTAGAIGYLFKRNASISGAEVGCQGEVGSACSMAAAGLAAVMGGTPEQVENA
AEIGIEHNLGLTCDPVGGLVQIPCIERNAMAANTAINAVRMAMLGDGSHIVTLDQAIETMKQTGEDMMAKYKETSKGGLA
VNVVEC

Specific function: Deaminates Also Threonine, Particularly When It Is Present In High Concentration. [C]

COG id: COG1760

COG function: function code E; L-serine deaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the iron-sulfur dependent L-serine dehydratase family [H]

Homologues:

Organism=Escherichia coli, GI1788116, Length=490, Percent_Identity=48.1632653061224, Blast_Score=419, Evalue=1e-118,
Organism=Escherichia coli, GI1789161, Length=487, Percent_Identity=48.4599589322382, Blast_Score=416, Evalue=1e-117,
Organism=Escherichia coli, GI48994925, Length=485, Percent_Identity=47.2164948453608, Blast_Score=404, Evalue=1e-114,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004644
- InterPro:   IPR005130
- InterPro:   IPR005131 [H]

Pfam domain/function: PF03313 SDH_alpha; PF03315 SDH_beta [H]

EC number: =4.3.1.17 [H]

Molecular weight: Translated: 51826; Mature: 51826

Theoretical pI: Translated: 4.93; Mature: 4.93

Prosite motif: PS00435 PEROXIDASE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
6.0 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
6.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFSVLDMFTIGVGPSSSHTVGPMVAAHAFASSLQADHLVDRTARVKITLYGSLALTGLGH
CCCHHEEHEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCEEEEEEEEEEEEEEECCC
GTDRAAMAGLEGNLPATVDTDHMMHIRETCALDDTLNLAGLRRIHFDYDRDVVFEQWKRM
CCCHHHHCCCCCCCCCEECCHHHHHHHHHHCCCCCCCHHHEEEEECCCCCHHHHHHHHHH
AAHPNGMRFQAFDAAASLVDEQVWYSIGGGFVRKGAPEDPMIGIHERPPEGTSFADADES
HCCCCCCEEEHHHHHHHHHHHHHHHHHCCCHHCCCCCCCCEECCCCCCCCCCCCCCCCCC
SSTDFGVEAPYPFSSCTELVSLCREHHLSIAELVWANETASRSGAQVRSDIDAIWRVMRA
CCCCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHH
CVDHGCTSAEPTLPGGLDVPRRAPKMYRRLALNSDVLRRDSRRKDAVLESSDAAWVDLFA
HHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCHHHHHHCCCHHHHHHCCCCCHHHHHEE
LAVSEENAGGGRIVTAPTNGSAGIIPAVLHYYWHFVDNANEQGVVTFLLTAGAIGYLFKR
EEEECCCCCCCEEEECCCCCCCCHHHHHHHHHHHHHCCCCCCCCEEEEEHHHHHHHHHHC
NASISGAEVGCQGEVGSACSMAAAGLAAVMGGTPEQVENAAEIGIEHNLGLTCDPVGGLV
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCEEECCCCCEE
QIPCIERNAMAANTAINAVRMAMLGDGSHIVTLDQAIETMKQTGEDMMAKYKETSKGGLA
ECCEECCCCHHHHHHHHHHHHHEECCCCEEEEHHHHHHHHHHCCHHHHHHHHHCCCCCEE
VNVVEC
EEEECC
>Mature Secondary Structure
MFSVLDMFTIGVGPSSSHTVGPMVAAHAFASSLQADHLVDRTARVKITLYGSLALTGLGH
CCCHHEEHEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCEEEEEEEEEEEEEEECCC
GTDRAAMAGLEGNLPATVDTDHMMHIRETCALDDTLNLAGLRRIHFDYDRDVVFEQWKRM
CCCHHHHCCCCCCCCCEECCHHHHHHHHHHCCCCCCCHHHEEEEECCCCCHHHHHHHHHH
AAHPNGMRFQAFDAAASLVDEQVWYSIGGGFVRKGAPEDPMIGIHERPPEGTSFADADES
HCCCCCCEEEHHHHHHHHHHHHHHHHHCCCHHCCCCCCCCEECCCCCCCCCCCCCCCCCC
SSTDFGVEAPYPFSSCTELVSLCREHHLSIAELVWANETASRSGAQVRSDIDAIWRVMRA
CCCCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHH
CVDHGCTSAEPTLPGGLDVPRRAPKMYRRLALNSDVLRRDSRRKDAVLESSDAAWVDLFA
HHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCHHHHHHCCCHHHHHHCCCCCHHHHHEE
LAVSEENAGGGRIVTAPTNGSAGIIPAVLHYYWHFVDNANEQGVVTFLLTAGAIGYLFKR
EEEECCCCCCCEEEECCCCCCCCHHHHHHHHHHHHHCCCCCCCCEEEEEHHHHHHHHHHC
NASISGAEVGCQGEVGSACSMAAAGLAAVMGGTPEQVENAAEIGIEHNLGLTCDPVGGLV
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCEEECCCCCEE
QIPCIERNAMAANTAINAVRMAMLGDGSHIVTLDQAIETMKQTGEDMMAKYKETSKGGLA
ECCEECCCCHHHHHHHHHHHHHEECCCCEEEEHHHHHHHHHHCCHHHHHHHHHCCCCCEE
VNVVEC
EEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12000953 [H]