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The map label for this gene is clpX [H]

Identifier: 213692574

GI number: 213692574

Start: 1867766

End: 1869145

Strand: Reverse

Name: clpX [H]

Synonym: Blon_1706

Alternate gene names: 213692574

Gene position: 1869145-1867766 (Counterclockwise)

Preceding gene: 213692575

Following gene: 213692573

Centisome position: 65.98

GC content: 58.48

Gene sequence:

>1380_bases
ATGGGACGTGTGGTGAGCTACAACGAGGACGTACCCCGTTGCACGTTCTGCGGCAAAACCGAACGTCAGGTCAGAAAACT
GGTGGCCGGTCCCAACGCCTCCATCTGCGATGAATGCATCGCCCTGTGCGTGGACATCATCTCCGAGGAGCGTGTCAAAG
ATGCCGAGGTCAATTCGCTGAGCCTGCCCAAGCCCGCCCAGATCTTCGATTATCTCAACCGCTACGTCATCGGTCAGGAG
AATGCCAAGCGCGCATTGTCCGTAGCCGTATACAACCATTACAAGCGCGTCAATATGGAGCTTCAGGAGTCCGCTGAACA
GCTCGACGGGAATAACGGGCACAGTGGCCAGACCGGCGAACAAGCCAAGCAATCCGCTCCCGCCCAGACGCGTGCTACCC
GCCGCAACAGTGACCCTTTGGCTGACGTTGAGGTCGCCAAATCAAACATTCTGTTGCTCGGCCCCACCGGTGTGGGCAAA
ACCTATCTTGCACAGGCGTTGGCCCGCGTAATGAACGTGCCATTCGTCATCACCGACGCCACCACCCTGACCGAGGCCGG
CTATGTAGGCGACGATGTGGAAACCGTGCTCCAACGTCTTCTCCAAGCCGCGGATGGCGACGTAAGCCGAGCCCAGCACG
GCATCATCTACATTGACGAAATCGATAAGATCGCGCGCAAATCAGGTGAGAACACCTCCATCACCCGTGACGTGTCCGGT
GAGGGCGTTCAGCAGGCGTTGCTGAAGATTTTGGAAGGCACCATCGCCTCCGTGCCGTTGGAGGGCACGCGCAAGCATAA
GGAGCAGGACACTGCGCAGATGGACACACGCGGCATCCTATTCATCTGCGGCGGTGCGTTCGTGGGACTGACGGATATTG
TTCGCAAGCGATTGGGCCGTCGAGAGACCGGCTTCGGCGCGAATTGGCACGACGCCGACATGAAAGACGAGGAATTGCTC
GAACAGGTCAATGCCGATGATCTGGCCGAGTTCGGGCTGTTGCCTGAGTTCATCGGACGTTTGCCGGTCACCAGTGTGCT
GAAGGAACTTACCGTAGACGATCTGACGGCGATTCTCACCCAGCCAGCCAACGCGCTGATCAAGCAGTACCGTAAGCTGT
TCGCCGTCGACGGCGTCGACCTGCAGTTCACCGAACAGGCCATTCGGGCGATTGCTGATATCGCCATCAAGCAGGGGACC
GGCGCACGCGGGTTGCGTTCGATTATCGAACGTACGTTGCAGGACACGATGTTCCAGTTGCCGAGTTTGGATGATGTGAA
GCAGGTGATTGTGGACAAGGCGTCCGTAGAGGGTTCCAGTACGCCCAAACTCCTGCGCGAAGCCGTGGATGTGCCGCAGG
GACGCCTCAAAGTTGCGTAG

Upstream 100 bases:

>100_bases
CCTCGGTCGGCAACGACCGGGGGTATTGTATTTCAAGGATGACAATGATAATGCGCAGCGTGGCGGTTCGACGGTGCGGC
GCAGTCGGCAAAGGAGAATC

Downstream 100 bases:

>100_bases
TCGGTTTTGCTTGACCGAGTCCGTACACATGCGGCGTGAGGCCAGTAAATACGCCGTTGCGGTGGCGATTAGGATGGTGC
GACTCGCCGCAACACGCCGA

Product: ATP-dependent protease ATP-binding subunit ClpX

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 459; Mature: 458

Protein sequence:

>459_residues
MGRVVSYNEDVPRCTFCGKTERQVRKLVAGPNASICDECIALCVDIISEERVKDAEVNSLSLPKPAQIFDYLNRYVIGQE
NAKRALSVAVYNHYKRVNMELQESAEQLDGNNGHSGQTGEQAKQSAPAQTRATRRNSDPLADVEVAKSNILLLGPTGVGK
TYLAQALARVMNVPFVITDATTLTEAGYVGDDVETVLQRLLQAADGDVSRAQHGIIYIDEIDKIARKSGENTSITRDVSG
EGVQQALLKILEGTIASVPLEGTRKHKEQDTAQMDTRGILFICGGAFVGLTDIVRKRLGRRETGFGANWHDADMKDEELL
EQVNADDLAEFGLLPEFIGRLPVTSVLKELTVDDLTAILTQPANALIKQYRKLFAVDGVDLQFTEQAIRAIADIAIKQGT
GARGLRSIIERTLQDTMFQLPSLDDVKQVIVDKASVEGSSTPKLLREAVDVPQGRLKVA

Sequences:

>Translated_459_residues
MGRVVSYNEDVPRCTFCGKTERQVRKLVAGPNASICDECIALCVDIISEERVKDAEVNSLSLPKPAQIFDYLNRYVIGQE
NAKRALSVAVYNHYKRVNMELQESAEQLDGNNGHSGQTGEQAKQSAPAQTRATRRNSDPLADVEVAKSNILLLGPTGVGK
TYLAQALARVMNVPFVITDATTLTEAGYVGDDVETVLQRLLQAADGDVSRAQHGIIYIDEIDKIARKSGENTSITRDVSG
EGVQQALLKILEGTIASVPLEGTRKHKEQDTAQMDTRGILFICGGAFVGLTDIVRKRLGRRETGFGANWHDADMKDEELL
EQVNADDLAEFGLLPEFIGRLPVTSVLKELTVDDLTAILTQPANALIKQYRKLFAVDGVDLQFTEQAIRAIADIAIKQGT
GARGLRSIIERTLQDTMFQLPSLDDVKQVIVDKASVEGSSTPKLLREAVDVPQGRLKVA
>Mature_458_residues
GRVVSYNEDVPRCTFCGKTERQVRKLVAGPNASICDECIALCVDIISEERVKDAEVNSLSLPKPAQIFDYLNRYVIGQEN
AKRALSVAVYNHYKRVNMELQESAEQLDGNNGHSGQTGEQAKQSAPAQTRATRRNSDPLADVEVAKSNILLLGPTGVGKT
YLAQALARVMNVPFVITDATTLTEAGYVGDDVETVLQRLLQAADGDVSRAQHGIIYIDEIDKIARKSGENTSITRDVSGE
GVQQALLKILEGTIASVPLEGTRKHKEQDTAQMDTRGILFICGGAFVGLTDIVRKRLGRRETGFGANWHDADMKDEELLE
QVNADDLAEFGLLPEFIGRLPVTSVLKELTVDDLTAILTQPANALIKQYRKLFAVDGVDLQFTEQAIRAIADIAIKQGTG
ARGLRSIIERTLQDTMFQLPSLDDVKQVIVDKASVEGSSTPKLLREAVDVPQGRLKVA

Specific function: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP [H]

COG id: COG1219

COG function: function code O; ATP-dependent protease Clp, ATPase subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ClpX chaperone family [H]

Homologues:

Organism=Homo sapiens, GI7242140, Length=506, Percent_Identity=39.9209486166008, Blast_Score=325, Evalue=5e-89,
Organism=Escherichia coli, GI1786642, Length=439, Percent_Identity=53.0751708428246, Blast_Score=442, Evalue=1e-125,
Organism=Escherichia coli, GI1790366, Length=212, Percent_Identity=33.0188679245283, Blast_Score=97, Evalue=3e-21,
Organism=Caenorhabditis elegans, GI71982905, Length=486, Percent_Identity=34.3621399176955, Blast_Score=300, Evalue=1e-81,
Organism=Caenorhabditis elegans, GI71982908, Length=432, Percent_Identity=36.3425925925926, Blast_Score=292, Evalue=3e-79,
Organism=Caenorhabditis elegans, GI71988663, Length=393, Percent_Identity=38.9312977099237, Blast_Score=259, Evalue=2e-69,
Organism=Caenorhabditis elegans, GI71988660, Length=251, Percent_Identity=41.8326693227092, Blast_Score=190, Evalue=1e-48,
Organism=Saccharomyces cerevisiae, GI6319704, Length=445, Percent_Identity=39.3258426966292, Blast_Score=275, Evalue=2e-74,
Organism=Drosophila melanogaster, GI24648291, Length=508, Percent_Identity=38.5826771653543, Blast_Score=323, Evalue=2e-88,
Organism=Drosophila melanogaster, GI24648289, Length=508, Percent_Identity=38.5826771653543, Blast_Score=323, Evalue=2e-88,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR013093
- InterPro:   IPR019489
- InterPro:   IPR004487
- InterPro:   IPR010603 [H]

Pfam domain/function: PF07724 AAA_2; PF10431 ClpB_D2-small; PF06689 zf-C4_ClpX [H]

EC number: NA

Molecular weight: Translated: 50115; Mature: 49983

Theoretical pI: Translated: 4.99; Mature: 4.99

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGRVVSYNEDVPRCTFCGKTERQVRKLVAGPNASICDECIALCVDIISEERVKDAEVNSL
CCCCCCCCCCCCCCEECCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCC
SLPKPAQIFDYLNRYVIGQENAKRALSVAVYNHYKRVNMELQESAEQLDGNNGHSGQTGE
CCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCHHHHHHHHHCCCCCCCCCCCHH
QAKQSAPAQTRATRRNSDPLADVEVAKSNILLLGPTGVGKTYLAQALARVMNVPFVITDA
HHHHCCCHHHHHHCCCCCCCHHHHHCCCCEEEECCCCCCHHHHHHHHHHHHCCCEEEECC
TTLTEAGYVGDDVETVLQRLLQAADGDVSRAQHGIIYIDEIDKIARKSGENTSITRDVSG
HHHHHCCCCCCHHHHHHHHHHHHCCCCHHHHHCCEEEEHHHHHHHHHCCCCCCEECCCCC
EGVQQALLKILEGTIASVPLEGTRKHKEQDTAQMDTRGILFICGGAFVGLTDIVRKRLGR
CHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHHCC
RETGFGANWHDADMKDEELLEQVNADDLAEFGLLPEFIGRLPVTSVLKELTVDDLTAILT
CCCCCCCCCCCCCCCHHHHHHHCCHHHHHHHCCHHHHHHCCCHHHHHHHHHHHHHHHHHH
QPANALIKQYRKLFAVDGVDLQFTEQAIRAIADIAIKQGTGARGLRSIIERTLQDTMFQL
CCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHC
PSLDDVKQVIVDKASVEGSSTPKLLREAVDVPQGRLKVA
CCHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCCCEECC
>Mature Secondary Structure 
GRVVSYNEDVPRCTFCGKTERQVRKLVAGPNASICDECIALCVDIISEERVKDAEVNSL
CCCCCCCCCCCCCEECCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCC
SLPKPAQIFDYLNRYVIGQENAKRALSVAVYNHYKRVNMELQESAEQLDGNNGHSGQTGE
CCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCHHHHHHHHHCCCCCCCCCCCHH
QAKQSAPAQTRATRRNSDPLADVEVAKSNILLLGPTGVGKTYLAQALARVMNVPFVITDA
HHHHCCCHHHHHHCCCCCCCHHHHHCCCCEEEECCCCCCHHHHHHHHHHHHCCCEEEECC
TTLTEAGYVGDDVETVLQRLLQAADGDVSRAQHGIIYIDEIDKIARKSGENTSITRDVSG
HHHHHCCCCCCHHHHHHHHHHHHCCCCHHHHHCCEEEEHHHHHHHHHCCCCCCEECCCCC
EGVQQALLKILEGTIASVPLEGTRKHKEQDTAQMDTRGILFICGGAFVGLTDIVRKRLGR
CHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHHCC
RETGFGANWHDADMKDEELLEQVNADDLAEFGLLPEFIGRLPVTSVLKELTVDDLTAILT
CCCCCCCCCCCCCCCHHHHHHHCCHHHHHHHCCHHHHHHCCCHHHHHHHHHHHHHHHHHH
QPANALIKQYRKLFAVDGVDLQFTEQAIRAIADIAIKQGTGARGLRSIIERTLQDTMFQL
CCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHC
PSLDDVKQVIVDKASVEGSSTPKLLREAVDVPQGRLKVA
CCHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCCCEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12381787 [H]