Click here to switch to the map view.

The map label for this gene is trpB [H]

Identifier: 213692251

GI number: 213692251

Start: 1538538

End: 1540625

Strand: Reverse

Name: trpB [H]

Synonym: Blon_1371

Alternate gene names: 213692251

Gene position: 1540625-1538538 (Counterclockwise)

Preceding gene: 213692253

Following gene: 213692250

Centisome position: 54.39

GC content: 64.61

Gene sequence:

>2088_bases
ATGTCGGTTTTGGACGAACTGGTGGCGGGAGCGCTGGAGGATCAGCGCACCCGTGAGCTCACCGTATCGCTTGAGGACGT
GAAGAAGGCCGCGCTGGCGGCCCCGGCTCCGATTGACGCGACACGATGGCTTAAGCGCGCCGACGGCATCCCCGTGATCG
CCGAGATCAAGCGCGCGTCTCCGTCCAAGGGCCACCTCTCCGACATCCCGGACCCGGCCGTACTGGCCCGCGAATACGAG
AAGGGCGGCGCAAGCGCCATCTCCGTGCTCACCGAAGGCCGCAAATTCCTCGGCAGCCTTGACGATTTCGACAAGGTCCG
CGCCGCCGTGCACATTCCGGTGCTGCGCAAGGACTTCATCGTCACCGACTACCAGATCTTCGAAGCCCGCGCCCACGGCG
CCGACCTGGTGCTGCTCATCGTCGCCGCATTGGACGACGCCCAGCTCAAGCACCTGCTGGATCTGGCGCACGAGTTGAGC
CTGACCGTGCTGGTCGAAACGCACACCCGCGAGGAAATCGAACGCGCCCGCAAGGCCGGTGCCAAGGTGATAGGCATCAA
CGCGCGCAACCTGAAGAACCTCAAGGTGGACGTGAACAAATACAACGAACTCGCGGCCGATCTGCCCGATGACGTCATCA
AGGTGGCGGAATCCGGCGTATTCGGGGCGGTCGAGGTCGAAGACTACGCCCGCGCGGGAGCGGACGCGGTACTGGTCGGT
GAAGGCGTGGCCACCGCTGATGATCATGAACTTGCAGTGGAACGACTAGTAAAGGCAGGAGCACAAGTGAAAGCATCCGA
AACAACCCCGCTCAGCGAACATCAGGGACCGTTTTGGGGACAGTTCGGCGGCCGCTATGTGCCCGAGGCCCTCATCACCG
CCCTCGACGAGCTGGAGCGCGTGTACACGCAAGCCAAGGCCGACCCCGAATTCCACAAGGAATTCATGACGCTCCAGCAG
CGTTACGTGGGCCGCCCGAGCCCGCTGACCGAAGCCCCGCGCTTCGCCGCACTCGTCAAGGAGAAGACCGATCTCGACGC
CCGTATCTTCCTCAAGCGCGAGGACTTGAACCACACCGGCGCGCACAAGATCAACAACGCGCTCGGACAGGCCCTGCTCG
TCAAGCGCATGGGCAAGACCCGCATGATCGCGGAGACCGGCGCCGGCCAGCACGGCGTGGCCACCGCCACCGTGTGCGCC
ATGCTTGGCCTCAAGTGCCGCATCTACATGGGCCAGATCGACGCCCGCCGCCAGGCCCTGAACGTGGCCCGCATGCGTAT
GCTCGGCGCCGAAGTGGTCGAGGTGACCCTCGGCGACAAGATTCTGAAGGACGCCATCAACGAGGCCCTGCGTGACTGGG
TTACCAACGTCAAGGACACGCACTACCTGCTCGGCACCGTCGCAGGCCCGCACCCGTTCCCGGCTATGGTGCGCGACTTC
CAGAAGATCATCGGCGAGGAAGCCAAGCAGCAGCTCCAGGACTGGTACGGCATCGACCATCCGGACGCGATCTGCGCCTG
CGTGGGCGGCGGCTCCAACGCCATCGGCGTGATGAACGCCTTCCTGGACGATGAGCGCGTGAACCTCTACGGCTACGAAG
CCGGCGGCAACGGCCCCGAATCCGGCAAGCACGCCATCCGCTTCGCCCCCGGCACCGGCCAGCTCGGCATGTTCCAGGGT
GCCAAGAGCTATCTGCTGGAAACCGACGAAGGCCAGACGCTCGACACCTACTCGATCTCTGCAGGCCTTGACTACGCTTC
CGTGGGGCCAGAGCACGCATGGCTCAAGGACATCGGCCGCGTGAACTACAGCTGGGCCACCGATGAGGAGGCCATGAACG
CCTTCCGCGACCTGAGCCAGAGCGAGGGCATCATCCCCGCCATCGAAAGCTCGCACGCCGTGGCCGGCGCGTACAAGGCC
GCCGCGGATCTGAAGGCCAAGGGCTATGACAAGGCCGTGATGATCGTGAACATCTCCGGCCGAGGCGACAAGGACATGGC
CACCGCCGGCAAGTGGTTTGGCTACCTGACCGACGATCAGGCCGCCGCGCTTGATGTGACCGGTGTCAACGGCAACACCG
TTGCCTGA

Upstream 100 bases:

>100_bases
GAACCAACGAGGAATAGCCCAGAATGTAGGACGGGTTCGGCAATCGGGACGGGGCGTGACCTAGAGTGGCGCATGACCGA
ACACCAACAAAGGGAGGACC

Downstream 100 bases:

>100_bases
ACAAGAAGAGGAGATTGTTGATTATGACCAACGAAGCGAATACGCCGTCCGGCCAGCCGCTGGGCATCAGCCACAAGCCC
AGCAAGTCGGGCGCTATGTT

Product: bifunctional indole-3-glycerol phosphate synthase/tryptophan synthase subunit beta

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 695; Mature: 694

Protein sequence:

>695_residues
MSVLDELVAGALEDQRTRELTVSLEDVKKAALAAPAPIDATRWLKRADGIPVIAEIKRASPSKGHLSDIPDPAVLAREYE
KGGASAISVLTEGRKFLGSLDDFDKVRAAVHIPVLRKDFIVTDYQIFEARAHGADLVLLIVAALDDAQLKHLLDLAHELS
LTVLVETHTREEIERARKAGAKVIGINARNLKNLKVDVNKYNELAADLPDDVIKVAESGVFGAVEVEDYARAGADAVLVG
EGVATADDHELAVERLVKAGAQVKASETTPLSEHQGPFWGQFGGRYVPEALITALDELERVYTQAKADPEFHKEFMTLQQ
RYVGRPSPLTEAPRFAALVKEKTDLDARIFLKREDLNHTGAHKINNALGQALLVKRMGKTRMIAETGAGQHGVATATVCA
MLGLKCRIYMGQIDARRQALNVARMRMLGAEVVEVTLGDKILKDAINEALRDWVTNVKDTHYLLGTVAGPHPFPAMVRDF
QKIIGEEAKQQLQDWYGIDHPDAICACVGGGSNAIGVMNAFLDDERVNLYGYEAGGNGPESGKHAIRFAPGTGQLGMFQG
AKSYLLETDEGQTLDTYSISAGLDYASVGPEHAWLKDIGRVNYSWATDEEAMNAFRDLSQSEGIIPAIESSHAVAGAYKA
AADLKAKGYDKAVMIVNISGRGDKDMATAGKWFGYLTDDQAAALDVTGVNGNTVA

Sequences:

>Translated_695_residues
MSVLDELVAGALEDQRTRELTVSLEDVKKAALAAPAPIDATRWLKRADGIPVIAEIKRASPSKGHLSDIPDPAVLAREYE
KGGASAISVLTEGRKFLGSLDDFDKVRAAVHIPVLRKDFIVTDYQIFEARAHGADLVLLIVAALDDAQLKHLLDLAHELS
LTVLVETHTREEIERARKAGAKVIGINARNLKNLKVDVNKYNELAADLPDDVIKVAESGVFGAVEVEDYARAGADAVLVG
EGVATADDHELAVERLVKAGAQVKASETTPLSEHQGPFWGQFGGRYVPEALITALDELERVYTQAKADPEFHKEFMTLQQ
RYVGRPSPLTEAPRFAALVKEKTDLDARIFLKREDLNHTGAHKINNALGQALLVKRMGKTRMIAETGAGQHGVATATVCA
MLGLKCRIYMGQIDARRQALNVARMRMLGAEVVEVTLGDKILKDAINEALRDWVTNVKDTHYLLGTVAGPHPFPAMVRDF
QKIIGEEAKQQLQDWYGIDHPDAICACVGGGSNAIGVMNAFLDDERVNLYGYEAGGNGPESGKHAIRFAPGTGQLGMFQG
AKSYLLETDEGQTLDTYSISAGLDYASVGPEHAWLKDIGRVNYSWATDEEAMNAFRDLSQSEGIIPAIESSHAVAGAYKA
AADLKAKGYDKAVMIVNISGRGDKDMATAGKWFGYLTDDQAAALDVTGVNGNTVA
>Mature_694_residues
SVLDELVAGALEDQRTRELTVSLEDVKKAALAAPAPIDATRWLKRADGIPVIAEIKRASPSKGHLSDIPDPAVLAREYEK
GGASAISVLTEGRKFLGSLDDFDKVRAAVHIPVLRKDFIVTDYQIFEARAHGADLVLLIVAALDDAQLKHLLDLAHELSL
TVLVETHTREEIERARKAGAKVIGINARNLKNLKVDVNKYNELAADLPDDVIKVAESGVFGAVEVEDYARAGADAVLVGE
GVATADDHELAVERLVKAGAQVKASETTPLSEHQGPFWGQFGGRYVPEALITALDELERVYTQAKADPEFHKEFMTLQQR
YVGRPSPLTEAPRFAALVKEKTDLDARIFLKREDLNHTGAHKINNALGQALLVKRMGKTRMIAETGAGQHGVATATVCAM
LGLKCRIYMGQIDARRQALNVARMRMLGAEVVEVTLGDKILKDAINEALRDWVTNVKDTHYLLGTVAGPHPFPAMVRDFQ
KIIGEEAKQQLQDWYGIDHPDAICACVGGGSNAIGVMNAFLDDERVNLYGYEAGGNGPESGKHAIRFAPGTGQLGMFQGA
KSYLLETDEGQTLDTYSISAGLDYASVGPEHAWLKDIGRVNYSWATDEEAMNAFRDLSQSEGIIPAIESSHAVAGAYKAA
ADLKAKGYDKAVMIVNISGRGDKDMATAGKWFGYLTDDQAAALDVTGVNGNTVA

Specific function: The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine [H]

COG id: COG0133

COG function: function code E; Tryptophan synthase beta chain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the trpB family [H]

Homologues:

Organism=Escherichia coli, GI1787515, Length=393, Percent_Identity=52.4173027989822, Blast_Score=411, Evalue=1e-116,
Organism=Escherichia coli, GI87081863, Length=205, Percent_Identity=42.9268292682927, Blast_Score=146, Evalue=3e-36,
Organism=Saccharomyces cerevisiae, GI6321412, Length=396, Percent_Identity=52.5252525252525, Blast_Score=409, Evalue=1e-115,
Organism=Saccharomyces cerevisiae, GI6322638, Length=214, Percent_Identity=42.9906542056075, Blast_Score=154, Evalue=6e-38,

Paralogues:

None

Copy number: 360 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 5,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001926
- InterPro:   IPR006653
- InterPro:   IPR006654
- InterPro:   IPR023026 [H]

Pfam domain/function: PF00291 PALP [H]

EC number: =4.2.1.20 [H]

Molecular weight: Translated: 75126; Mature: 74995

Theoretical pI: Translated: 5.28; Mature: 5.28

Prosite motif: PS00614 IGPS ; PS00168 TRP_SYNTHASE_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVLDELVAGALEDQRTRELTVSLEDVKKAALAAPAPIDATRWLKRADGIPVIAEIKRAS
CCHHHHHHHHHHCCCCHHHEEEEHHHHHHHHHCCCCCCCHHHHHHHCCCCCEEHHHHHCC
PSKGHLSDIPDPAVLAREYEKGGASAISVLTEGRKFLGSLDDFDKVRAAVHIPVLRKDFI
CCCCCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCHHHHHHHHEECCCHHCCCE
VTDYQIFEARAHGADLVLLIVAALDDAQLKHLLDLAHELSLTVLVETHTREEIERARKAG
EECHHHHHHHCCCCCEEEHHHHHCCHHHHHHHHHHHHHCEEEEEEECCCHHHHHHHHHCC
AKVIGINARNLKNLKVDVNKYNELAADLPDDVIKVAESGVFGAVEVEDYARAGADAVLVG
CEEEEECCCCCCEEEEEHHHHHHHHHCCCHHHHHHHHCCCEEEEEHHHHHHCCCCEEEEE
EGVATADDHELAVERLVKAGAQVKASETTPLSEHQGPFWGQFGGRYVPEALITALDELER
CCCCCCCHHHHHHHHHHHCCCCEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHH
VYTQAKADPEFHKEFMTLQQRYVGRPSPLTEAPRFAALVKEKTDLDARIFLKREDLNHTG
HHHHHCCCHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCCCEEEEEEECCCCCCC
AHKINNALGQALLVKRMGKTRMIAETGAGQHGVATATVCAMLGLKCRIYMGQIDARRQAL
HHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHHHCCEEEEEECCHHHHHHHH
NVARMRMLGAEVVEVTLGDKILKDAINEALRDWVTNVKDTHYLLGTVAGPHPFPAMVRDF
HHHHHHHHHHHHEEEHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCHHHHHHH
QKIIGEEAKQQLQDWYGIDHPDAICACVGGGSNAIGVMNAFLDDERVNLYGYEAGGNGPE
HHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCHHHHHHHHHCCCCEEEEEEECCCCCCC
SGKHAIRFAPGTGQLGMFQGAKSYLLETDEGQTLDTYSISAGLDYASVGPEHAWLKDIGR
CCCCEEEECCCCCCCCHHHCCHHHEEECCCCCEEEEEEECCCCCHHHCCCCHHHHHHHHC
VNYSWATDEEAMNAFRDLSQSEGIIPAIESSHAVAGAYKAAADLKAKGYDKAVMIVNISG
CCCCCCCCHHHHHHHHHHHHCCCCCEECCCCCHHHHHHHHHHHCCCCCCCCEEEEEEECC
RGDKDMATAGKWFGYLTDDQAAALDVTGVNGNTVA
CCCCCHHHHHHHCEEECCCCCCEEEEECCCCCCCC
>Mature Secondary Structure 
SVLDELVAGALEDQRTRELTVSLEDVKKAALAAPAPIDATRWLKRADGIPVIAEIKRAS
CHHHHHHHHHHCCCCHHHEEEEHHHHHHHHHCCCCCCCHHHHHHHCCCCCEEHHHHHCC
PSKGHLSDIPDPAVLAREYEKGGASAISVLTEGRKFLGSLDDFDKVRAAVHIPVLRKDFI
CCCCCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCHHHHHHHHEECCCHHCCCE
VTDYQIFEARAHGADLVLLIVAALDDAQLKHLLDLAHELSLTVLVETHTREEIERARKAG
EECHHHHHHHCCCCCEEEHHHHHCCHHHHHHHHHHHHHCEEEEEEECCCHHHHHHHHHCC
AKVIGINARNLKNLKVDVNKYNELAADLPDDVIKVAESGVFGAVEVEDYARAGADAVLVG
CEEEEECCCCCCEEEEEHHHHHHHHHCCCHHHHHHHHCCCEEEEEHHHHHHCCCCEEEEE
EGVATADDHELAVERLVKAGAQVKASETTPLSEHQGPFWGQFGGRYVPEALITALDELER
CCCCCCCHHHHHHHHHHHCCCCEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHH
VYTQAKADPEFHKEFMTLQQRYVGRPSPLTEAPRFAALVKEKTDLDARIFLKREDLNHTG
HHHHHCCCHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCCCEEEEEEECCCCCCC
AHKINNALGQALLVKRMGKTRMIAETGAGQHGVATATVCAMLGLKCRIYMGQIDARRQAL
HHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHHHCCEEEEEECCHHHHHHHH
NVARMRMLGAEVVEVTLGDKILKDAINEALRDWVTNVKDTHYLLGTVAGPHPFPAMVRDF
HHHHHHHHHHHHEEEHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCHHHHHHH
QKIIGEEAKQQLQDWYGIDHPDAICACVGGGSNAIGVMNAFLDDERVNLYGYEAGGNGPE
HHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCHHHHHHHHHCCCCEEEEEEECCCCCCC
SGKHAIRFAPGTGQLGMFQGAKSYLLETDEGQTLDTYSISAGLDYASVGPEHAWLKDIGR
CCCCEEEECCCCCCCCHHHCCHHHEEECCCCCEEEEEEECCCCCHHHCCCCHHHHHHHHC
VNYSWATDEEAMNAFRDLSQSEGIIPAIESSHAVAGAYKAAADLKAKGYDKAVMIVNISG
CCCCCCCCHHHHHHHHHHHHCCCCCEECCCCCHHHHHHHHHHHCCCCCCCCEEEEEEECC
RGDKDMATAGKWFGYLTDDQAAALDVTGVNGNTVA
CCCCCHHHHHHHCEEECCCCCCEEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA