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The map label for this gene is ruvA

Identifier: 213692039

GI number: 213692039

Start: 1339010

End: 1339636

Strand: Direct

Name: ruvA

Synonym: Blon_1157

Alternate gene names: 213692039

Gene position: 1339010-1339636 (Clockwise)

Preceding gene: 213692038

Following gene: 213692040

Centisome position: 47.27

GC content: 65.55

Gene sequence:

>627_bases
ATGATTGGCATGCTGACCGGGCGGGTGGAATCGGTTGAAACCGACACCGCATTGATCGACGTCGGGGGAGTGGGCTATGA
GACGCGCATGCCCGCCACCGACTTGGGCCGCCTGCACGCCGGCCAGGACGCCTGCGTCTTCACGTATCTGAACCTCTCGC
AGGATTCTGTCACACTGTACGGGTTCCTCGACCGGGACTCCAAGAGAGTGTTCCTGCAGCTCATCAAGGTCTCCGGCATA
GGACCGAAGGTGGCGCAGTCGCTGCTGGGCACGATGACCCCAAGCCAGCTGGCCCGCGCCATCGCCGACAATGACGCCGC
CGCACTGGCCAAGGCGCCGGGATTGGGCAGGAAGGGCGCGCAGAAGATCATCCTGGAGCTCAAGGGATCCGTCGATCTGA
ACCAGTCCGATGACGCGTCGGCCGGCAACGCTCCATACCAGCCGACCGTCGACGCCGGCGTGGAGCAGGTCGTGGAGGGG
CTGGTCTCTCTTGGCTGGCGTCAGCAGGACGCTCAGCGGGCCGTCAACGAAGCCTGCGCAGAGAACGATGTTCCCATGCC
GCTGGCCTCCGACGATGCGCCGCGTGTGCTGCGGCTCGCCTTGGCCCGTATGGATAGGGGGCGCTGA

Upstream 100 bases:

>100_bases
AAACTCCACGCGCCGACGCAAGAACAGCGATCGAGGTATGTAGTATACTTTCGAACAGATGTTCGAATCCTGAATACCGA
AACGTTCAAGGAGTACCTGT

Downstream 100 bases:

>100_bases
TGAACGAGACGACGGATTACGGCGCCTCCAACACCGGTGCCAACGAGGAGTCGTTACGCATGGTCTCCTCGCAGCCGATC
GGCAACGAGCCGGCCAGCGA

Product: Holliday junction DNA helicase RuvA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 208; Mature: 208

Protein sequence:

>208_residues
MIGMLTGRVESVETDTALIDVGGVGYETRMPATDLGRLHAGQDACVFTYLNLSQDSVTLYGFLDRDSKRVFLQLIKVSGI
GPKVAQSLLGTMTPSQLARAIADNDAAALAKAPGLGRKGAQKIILELKGSVDLNQSDDASAGNAPYQPTVDAGVEQVVEG
LVSLGWRQQDAQRAVNEACAENDVPMPLASDDAPRVLRLALARMDRGR

Sequences:

>Translated_208_residues
MIGMLTGRVESVETDTALIDVGGVGYETRMPATDLGRLHAGQDACVFTYLNLSQDSVTLYGFLDRDSKRVFLQLIKVSGI
GPKVAQSLLGTMTPSQLARAIADNDAAALAKAPGLGRKGAQKIILELKGSVDLNQSDDASAGNAPYQPTVDAGVEQVVEG
LVSLGWRQQDAQRAVNEACAENDVPMPLASDDAPRVLRLALARMDRGR
>Mature_208_residues
MIGMLTGRVESVETDTALIDVGGVGYETRMPATDLGRLHAGQDACVFTYLNLSQDSVTLYGFLDRDSKRVFLQLIKVSGI
GPKVAQSLLGTMTPSQLARAIADNDAAALAKAPGLGRKGAQKIILELKGSVDLNQSDDASAGNAPYQPTVDAGVEQVVEG
LVSLGWRQQDAQRAVNEACAENDVPMPLASDDAPRVLRLALARMDRGR

Specific function: The ruvA-ruvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is an helicase that mediates the Holliday

COG id: COG0632

COG function: function code L; Holliday junction resolvasome, DNA-binding subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ruvA family

Homologues:

Organism=Escherichia coli, GI1788168, Length=183, Percent_Identity=36.6120218579235, Blast_Score=125, Evalue=1e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RUVA_BIFLI (B7GR17)

Other databases:

- EMBL:   CP001095
- RefSeq:   YP_002322625.1
- GeneID:   7053323
- GenomeReviews:   CP001095_GR
- KEGG:   bln:Blon_1157
- HOGENOM:   HBG635309
- ProtClustDB:   CLSK572756
- HAMAP:   MF_00031
- InterPro:   IPR011114
- InterPro:   IPR013849
- InterPro:   IPR003583
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR000085
- InterPro:   IPR010994
- Gene3D:   G3DSA:2.40.50.140
- SMART:   SM00278
- TIGRFAMs:   TIGR00084

Pfam domain/function: PF07499 RuvA_C; PF01330 RuvA_N; SSF50249 Nucleic_acid_OB; SSF47781 RuvA_2_like; SSF46929 RuvA_C-like

EC number: =3.6.4.12

Molecular weight: Translated: 22051; Mature: 22051

Theoretical pI: Translated: 4.72; Mature: 4.72

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIGMLTGRVESVETDTALIDVGGVGYETRMPATDLGRLHAGQDACVFTYLNLSQDSVTLY
CCCCCCCCCCCCCCCEEEEEECCCCCCCCCCHHHHHHHCCCCCCEEEEEEECCCCCEEEE
GFLDRDSKRVFLQLIKVSGIGPKVAQSLLGTMTPSQLARAIADNDAAALAKAPGLGRKGA
EEECCCHHHHHHHHHHHCCCCHHHHHHHHHCCCHHHHHHHHHCCCHHHHHCCCCCCCHHH
QKIILELKGSVDLNQSDDASAGNAPYQPTVDAGVEQVVEGLVSLGWRQQDAQRAVNEACA
HHHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
ENDVPMPLASDDAPRVLRLALARMDRGR
CCCCCCCCCCCCHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MIGMLTGRVESVETDTALIDVGGVGYETRMPATDLGRLHAGQDACVFTYLNLSQDSVTLY
CCCCCCCCCCCCCCCEEEEEECCCCCCCCCCHHHHHHHCCCCCCEEEEEEECCCCCEEEE
GFLDRDSKRVFLQLIKVSGIGPKVAQSLLGTMTPSQLARAIADNDAAALAKAPGLGRKGA
EEECCCHHHHHHHHHHHCCCCHHHHHHHHHCCCHHHHHHHHHCCCHHHHHCCCCCCCHHH
QKIILELKGSVDLNQSDDASAGNAPYQPTVDAGVEQVVEGLVSLGWRQQDAQRAVNEACA
HHHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
ENDVPMPLASDDAPRVLRLALARMDRGR
CCCCCCCCCCCCHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA