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The map label for this gene is ruvC [H]

Identifier: 213692038

GI number: 213692038

Start: 1338368

End: 1338952

Strand: Direct

Name: ruvC [H]

Synonym: Blon_1156

Alternate gene names: 213692038

Gene position: 1338368-1338952 (Clockwise)

Preceding gene: 213692037

Following gene: 213692039

Centisome position: 47.25

GC content: 66.84

Gene sequence:

>585_bases
GTGATCATCCTCGGCGTCGACCCCGGGCTCACGCGCTGCGGGGTCGGCGTGATCGAAGCCGGCGAGCACCGCCGGCTTTC
GTTTATTCACGTGGACGTGGTGCGGTCCTCGCCGGACATCACCCAGGATCTGCGTCTTTTGGCCATCTATAACGGCCTGT
CCGAGAAGATGGATCGCTTTGCACCCGATGCCGTGTCCATCGAACGTGTGTTCGCCCAGTCGAATCGCAACACTGTGCTC
GGTACCGCGCAGGCGGCCGGCCTTGCCATGCTCGCCGCCGCGCAACGCGGCATCCCCGTGGCGCTTCATACCCCGACCGA
GGCGAAACTGGCCATCACCGGCAACGGGCAGGCGCAGAAGGTGCAGGTGGAACGCATGGTGACGCGTGTCCTGAACCTTA
CCAAGATGCCGACGCCCGCCGACGCCGCCGACGCGCTGGCCTTGGCCATATGCCATGCCCTGCGTCCGGCGGGGGCGCTG
CAGGGCGGCGAGCGTGAGCAGCATCTGACCGCCGCGCAACGCCAGTGGGCCGAGGCCGCGCAAAACTCCACGCGCCGACG
CAAGAACAGCGATCGAGGTATGTAG

Upstream 100 bases:

>100_bases
TCATCGACAACCTCGATGATCTCGACGATGTGCAGAACATCTACTCCAACTGGACCGCCTCCGACGAGGTGATGGCCCAG
CTCGACGAGGAGTAATCCTC

Downstream 100 bases:

>100_bases
TATACTTTCGAACAGATGTTCGAATCCTGAATACCGAAACGTTCAAGGAGTACCTGTATGATTGGCATGCTGACCGGGCG
GGTGGAATCGGTTGAAACCG

Product: Holliday junction resolvase

Products: NA

Alternate protein names: Holliday junction nuclease ruvC; Holliday junction resolvase ruvC [H]

Number of amino acids: Translated: 194; Mature: 194

Protein sequence:

>194_residues
MIILGVDPGLTRCGVGVIEAGEHRRLSFIHVDVVRSSPDITQDLRLLAIYNGLSEKMDRFAPDAVSIERVFAQSNRNTVL
GTAQAAGLAMLAAAQRGIPVALHTPTEAKLAITGNGQAQKVQVERMVTRVLNLTKMPTPADAADALALAICHALRPAGAL
QGGEREQHLTAAQRQWAEAAQNSTRRRKNSDRGM

Sequences:

>Translated_194_residues
MIILGVDPGLTRCGVGVIEAGEHRRLSFIHVDVVRSSPDITQDLRLLAIYNGLSEKMDRFAPDAVSIERVFAQSNRNTVL
GTAQAAGLAMLAAAQRGIPVALHTPTEAKLAITGNGQAQKVQVERMVTRVLNLTKMPTPADAADALALAICHALRPAGAL
QGGEREQHLTAAQRQWAEAAQNSTRRRKNSDRGM
>Mature_194_residues
MIILGVDPGLTRCGVGVIEAGEHRRLSFIHVDVVRSSPDITQDLRLLAIYNGLSEKMDRFAPDAVSIERVFAQSNRNTVL
GTAQAAGLAMLAAAQRGIPVALHTPTEAKLAITGNGQAQKVQVERMVTRVLNLTKMPTPADAADALALAICHALRPAGAL
QGGEREQHLTAAQRQWAEAAQNSTRRRKNSDRGM

Specific function: Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leav

COG id: COG0817

COG function: function code L; Holliday junction resolvasome, endonuclease subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ruvC family [H]

Homologues:

Organism=Escherichia coli, GI1788170, Length=139, Percent_Identity=38.8489208633094, Blast_Score=86, Evalue=2e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012337
- InterPro:   IPR020563
- InterPro:   IPR002176 [H]

Pfam domain/function: PF02075 RuvC [H]

EC number: =3.1.22.4 [H]

Molecular weight: Translated: 20819; Mature: 20819

Theoretical pI: Translated: 10.34; Mature: 10.34

Prosite motif: PS01321 RUVC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIILGVDPGLTRCGVGVIEAGEHRRLSFIHVDVVRSSPDITQDLRLLAIYNGLSEKMDRF
CEEEECCCCCHHHCCCEEECCCCCEEEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHH
APDAVSIERVFAQSNRNTVLGTAQAAGLAMLAAAQRGIPVALHTPTEAKLAITGNGQAQK
CCCHHHHHHHHHHCCCCEEEECHHHHHHHHHHHHHCCCCEEEECCCCCEEEEECCCCHHH
VQVERMVTRVLNLTKMPTPADAADALALAICHALRPAGALQGGEREQHLTAAQRQWAEAA
HHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHH
QNSTRRRKNSDRGM
HHHHHHHCCCCCCC
>Mature Secondary Structure
MIILGVDPGLTRCGVGVIEAGEHRRLSFIHVDVVRSSPDITQDLRLLAIYNGLSEKMDRF
CEEEECCCCCHHHCCCEEECCCCCEEEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHH
APDAVSIERVFAQSNRNTVLGTAQAAGLAMLAAAQRGIPVALHTPTEAKLAITGNGQAQK
CCCHHHHHHHHHHCCCCEEEECHHHHHHHHHHHHHCCCCEEEECCCCCEEEEECCCCHHH
VQVERMVTRVLNLTKMPTPADAADALALAICHALRPAGALQGGEREQHLTAAQRQWAEAA
HHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHH
QNSTRRRKNSDRGM
HHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA