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The map label for this gene is mraY [H]

Identifier: 213691747

GI number: 213691747

Start: 1005654

End: 1006739

Strand: Direct

Name: mraY [H]

Synonym: Blon_0853

Alternate gene names: 213691747

Gene position: 1005654-1006739 (Clockwise)

Preceding gene: 213691746

Following gene: 213691748

Centisome position: 35.5

GC content: 58.75

Gene sequence:

>1086_bases
ATGCTGGTGTCGCTCATCGTCACCCTGGTCGGCACCCCGCTGCTGATTCGGCTGGTCCACAAGCTGCACTATGGCCAGTA
CATCCGCCAGGATGGGCCGCAGTCGCATCTGGTCAAGCGCGGCACCCCCACGTTGGGCGGCGTGGTCATCAACTTCGCGA
TTCTGCTCGGTTGGGCATCCTCCGCACTGTACCGATACCTGCGTTCGGACGATGTGCCCTCCTGGTCCGCGGTGCTCGTA
CTGTTCGCCATGCTGTCGATGGGTCTGCTGGGCTTTATCGACGACTTCGCCAAGGTGCGTAAGAAGCAGAACGAAGGCCT
ATCGGTGACCGGCAAGTTCATCGGCCAGTTCATCTTCGCCACCATATACGCGGTGCTGGCGCTGCTGATTCCCACCAAAT
CGGGTTTCCCCAGTGCGCAGGCGGGCATCAGCTTCATCGAACGGCCGTTCTTCAACTTCGACTTCGCCGGTCGAACCGTG
GCCATCATCCTGTTCGTCATCTGGGTGAACTTCCTGATGACCGCATGGACCAACGCAGTGAATCTGACGGATGGGCTTGA
CGGTCTGGCGGCAGGTTCGTCGATGATCGCCTTCACCGGTTTTGGCATCATCGCATTCTGGGAAAGCTACCACATCAAGG
GCGGCAGCCATGGCGGATATTCCTATGCCGTGTCCGATCCTCTCGATCTGACCGTCATCGCCGTATGCGCGGCCGTCGCC
TGCTTCGGCTTCTTGTGGTACAACTCGAACCCCGCATCGATTTTCATGGGTGATACCGGTTCCCTGGCCTTGGGTGGTCT
GTTCGCAGCCCTGTCCATCGCCACGCACACCGAATTCCTGGCGGTGGTTCTGGGTGGACTGTACGTCATGGAAGCCATGA
GCGACGTCATCCAGGTCGGGTACTTCAAGATGACCCACAAACGTGTATTCAAAATGGCACCGATCCACCATCATTTCGAA
CTGAAGGGTTGGACCGAAACCAAGGTGGTGGTGCGGTTCTGGATGATCGAACTCATCTTCGTGCTGCTCGCCCTGACGAT
TTTCTACGGCGACTGGGTCACCCGCTCCGGCCTGCTGTTCAGCTAG

Upstream 100 bases:

>100_bases
TGAGCGCTTTGGCTGAACGCTGGGCAAAGAACTGACCTGATAACCATCCCAAGAAACCGACAAGAAAGAGAAGCTGCACG
TGATTGCTCTGATCATTGGA

Downstream 100 bases:

>100_bases
CGGAAATCTGGGTGGATTATGCTCACCCACGGAATTCCTATATCAGGAGGAACAATGCAAGTAGCGGATAAGACAGTGGT
GATCGCCGGACTGGGGGTAT

Product: phospho-N-acetylmuramoyl-pentapeptide- transferase

Products: NA

Alternate protein names: UDP-MurNAc-pentapeptide phosphotransferase [H]

Number of amino acids: Translated: 361; Mature: 361

Protein sequence:

>361_residues
MLVSLIVTLVGTPLLIRLVHKLHYGQYIRQDGPQSHLVKRGTPTLGGVVINFAILLGWASSALYRYLRSDDVPSWSAVLV
LFAMLSMGLLGFIDDFAKVRKKQNEGLSVTGKFIGQFIFATIYAVLALLIPTKSGFPSAQAGISFIERPFFNFDFAGRTV
AIILFVIWVNFLMTAWTNAVNLTDGLDGLAAGSSMIAFTGFGIIAFWESYHIKGGSHGGYSYAVSDPLDLTVIAVCAAVA
CFGFLWYNSNPASIFMGDTGSLALGGLFAALSIATHTEFLAVVLGGLYVMEAMSDVIQVGYFKMTHKRVFKMAPIHHHFE
LKGWTETKVVVRFWMIELIFVLLALTIFYGDWVTRSGLLFS

Sequences:

>Translated_361_residues
MLVSLIVTLVGTPLLIRLVHKLHYGQYIRQDGPQSHLVKRGTPTLGGVVINFAILLGWASSALYRYLRSDDVPSWSAVLV
LFAMLSMGLLGFIDDFAKVRKKQNEGLSVTGKFIGQFIFATIYAVLALLIPTKSGFPSAQAGISFIERPFFNFDFAGRTV
AIILFVIWVNFLMTAWTNAVNLTDGLDGLAAGSSMIAFTGFGIIAFWESYHIKGGSHGGYSYAVSDPLDLTVIAVCAAVA
CFGFLWYNSNPASIFMGDTGSLALGGLFAALSIATHTEFLAVVLGGLYVMEAMSDVIQVGYFKMTHKRVFKMAPIHHHFE
LKGWTETKVVVRFWMIELIFVLLALTIFYGDWVTRSGLLFS
>Mature_361_residues
MLVSLIVTLVGTPLLIRLVHKLHYGQYIRQDGPQSHLVKRGTPTLGGVVINFAILLGWASSALYRYLRSDDVPSWSAVLV
LFAMLSMGLLGFIDDFAKVRKKQNEGLSVTGKFIGQFIFATIYAVLALLIPTKSGFPSAQAGISFIERPFFNFDFAGRTV
AIILFVIWVNFLMTAWTNAVNLTDGLDGLAAGSSMIAFTGFGIIAFWESYHIKGGSHGGYSYAVSDPLDLTVIAVCAAVA
CFGFLWYNSNPASIFMGDTGSLALGGLFAALSIATHTEFLAVVLGGLYVMEAMSDVIQVGYFKMTHKRVFKMAPIHHHFE
LKGWTETKVVVRFWMIELIFVLLALTIFYGDWVTRSGLLFS

Specific function: First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan [H]

COG id: COG0472

COG function: function code M; UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 4 family. MraY subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786275, Length=345, Percent_Identity=37.6811594202899, Blast_Score=216, Evalue=3e-57,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000715
- InterPro:   IPR003524
- InterPro:   IPR018480 [H]

Pfam domain/function: PF00953 Glycos_transf_4 [H]

EC number: =2.7.8.13 [H]

Molecular weight: Translated: 39632; Mature: 39632

Theoretical pI: Translated: 8.92; Mature: 8.92

Prosite motif: PS01348 MRAY_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLVSLIVTLVGTPLLIRLVHKLHYGQYIRQDGPQSHLVKRGTPTLGGVVINFAILLGWAS
CHHHHHHHHHCHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCHHHHHHHHHHHHHHHH
SALYRYLRSDDVPSWSAVLVLFAMLSMGLLGFIDDFAKVRKKQNEGLSVTGKFIGQFIFA
HHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEHHHHHHHHHHH
TIYAVLALLIPTKSGFPSAQAGISFIERPFFNFDFAGRTVAIILFVIWVNFLMTAWTNAV
HHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCC
NLTDGLDGLAAGSSMIAFTGFGIIAFWESYHIKGGSHGGYSYAVSDPLDLTVIAVCAAVA
CCCCCCCHHHCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCEEEECCCCHHHHHHHHHHHH
CFGFLWYNSNPASIFMGDTGSLALGGLFAALSIATHTEFLAVVLGGLYVMEAMSDVIQVG
HHHHHHCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YFKMTHKRVFKMAPIHHHFELKGWTETKVVVRFWMIELIFVLLALTIFYGDWVTRSGLLF
HHHHHHHHHHHHCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
S
C
>Mature Secondary Structure
MLVSLIVTLVGTPLLIRLVHKLHYGQYIRQDGPQSHLVKRGTPTLGGVVINFAILLGWAS
CHHHHHHHHHCHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCHHHHHHHHHHHHHHHH
SALYRYLRSDDVPSWSAVLVLFAMLSMGLLGFIDDFAKVRKKQNEGLSVTGKFIGQFIFA
HHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEHHHHHHHHHHH
TIYAVLALLIPTKSGFPSAQAGISFIERPFFNFDFAGRTVAIILFVIWVNFLMTAWTNAV
HHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCC
NLTDGLDGLAAGSSMIAFTGFGIIAFWESYHIKGGSHGGYSYAVSDPLDLTVIAVCAAVA
CCCCCCCHHHCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCEEEECCCCHHHHHHHHHHHH
CFGFLWYNSNPASIFMGDTGSLALGGLFAALSIATHTEFLAVVLGGLYVMEAMSDVIQVG
HHHHHHCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YFKMTHKRVFKMAPIHHHFELKGWTETKVVVRFWMIELIFVLLALTIFYGDWVTRSGLLF
HHHHHHHHHHHHCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
S
C

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA