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The map label for this gene is yqjI [H]

Identifier: 213691128

GI number: 213691128

Start: 250169

End: 251698

Strand: Direct

Name: yqjI [H]

Synonym: Blon_0207

Alternate gene names: 213691128

Gene position: 250169-251698 (Clockwise)

Preceding gene: 213691127

Following gene: 213691132

Centisome position: 8.83

GC content: 61.11

Gene sequence:

>1530_bases
ATGATTCCCTCCGCTGATGCGCTGTTTTGTGACGCGCGTGATGACGATGGGACAATCAAACGAAAGGCAAGGCACATGGC
CGAAGCTACAGCAAACATTGGTGTGATCGGACTGGCCGCGATGGGCTCCAATCTGGCGCGTAATCTGGCGCACCATGGCA
ATACGGTGGCGTTGTTCAACCGTCACTACTCGCGTACCGAGAAGCTCATGAACGAGCATGGCGCCGAAGGCAACTTTGTG
CCGGCCGAGACGCTCGAGGAATTCGCCGCGTCCCTGAAGCGTCCGCGTACCGCCATCATCATGGTCAAGGCCGGTGCTCC
GACCGACGCGACCATCGCGCAGCTAGAAGAGGTGTTCGAACCGGGCGACATCATCGTCGACGGTGGCAACTCCTTCTTCA
AGGACACCATCAAGCGTGAGAAGGAAGTACGTGCTAAGGGCTTCCACTTCGTGGGCTGCGGCGTGTCCGGCGGCGAGGAG
GGCGCGCTCAACGGCCCGTCCCTGATGCCCGGCGGCACCGTGGAATCCTGGAAGACCCTGGGGCCGATTCTGGAATCCAT
CGCCGCCAAGGTGAACGGCGAACCGTGCGTGACCCACATCGGCACCGATGGCGCCGGCCACTTTGTCAAGATGGTGCACA
ACGGCATCGAGTATGCGGATATGCAGGTGATTGGTGAGGCGTATGACATTCTGCGCCGTGGACTCGGCATGGATGCCGAG
GAGATCGGCGACGTGTTCGAGGAGTGGAACAAGGGCGATCTCGACTCCTACCTGATCGAGATCACCGCCCAGATCCTGCA
CCATAAGGATGCCGAGACCGGCAAGCCGTTCGTGGACATGGTCGTGGATCATGCCGGCATGAAGGGTACTGGTACGTGGA
CCGTGCAGACTGGTCTGGAATTTGGTTCTCCTGTGGCTGCCATCGGTGAAGCCGTGTTCGCTCGTGCACTGTCTTCGCAC
GGTGAGCTGCGTGAAGACGCTCAGAAGGAAGGTCTGGCTGGCCCGAACAAGACCATCGATCTGGCCGGAGAAGACGAGGC
CGCGTTCGTCGATGACGTGCGCAAGGCCCTGTTCGCTTCCAAGGTCGTGGCCTATGCTCAGGGCCTGAACGAGATTCAGG
ACGGTGCCAAGGAATACGGCTGGGATATCAACCTGTCCGAAGTGGCCCGCATTTGGCGTGGCGGCTGCATTATTCGCGCC
CAGTTCCTGCTCGACCGCATCACCGAGGCCTTCAAGGGCGATAACCCGCCGGCTTCCCTGCTGTTCGATCCGTACTTCGA
GAAGATCATCGGCGAATCGCAGGACGCATGGCGTCGCGTGATCGTTCGCGCGGTGGAGGCCGGCATACCGACCCCGGTGT
TCTCCAGCTCCCTGGCTTACTACGATGGTCTGCGCTCCAAGCGTCTGCCCACCGCTCTGACCCAGTCCCAGCGTGACCTC
TTCGGTGCCCACACCTACGGCCGCGTCGACAAGCCCGGCGTGTTCCACACGCTGTGGGCTGAAGAAGGCAAGCCTGAAAT
CGAGGCGTAG

Upstream 100 bases:

>100_bases
AATGGCAAGTAATTACGCTTCGCGGGCAGAAGGTGCGTAGAGCCTAAGACAGCCCTCGTGCGTGGGTGATAAGCGGGATA
CACTTTCAAGCGTTGAAGGA

Downstream 100 bases:

>100_bases
CCTCGTGATTTCAGGCTTAGGACAGCCCTGTGGGCTGTCCGGCCTTCTTCAGGCTCGGCGATAGCCGAGCTGAGAAAACA
GCAAGCCTGAGATCGAGGCG

Product: 6-phosphogluconate dehydrogenase

Products: NA

Alternate protein names: GNTZII [H]

Number of amino acids: Translated: 509; Mature: 509

Protein sequence:

>509_residues
MIPSADALFCDARDDDGTIKRKARHMAEATANIGVIGLAAMGSNLARNLAHHGNTVALFNRHYSRTEKLMNEHGAEGNFV
PAETLEEFAASLKRPRTAIIMVKAGAPTDATIAQLEEVFEPGDIIVDGGNSFFKDTIKREKEVRAKGFHFVGCGVSGGEE
GALNGPSLMPGGTVESWKTLGPILESIAAKVNGEPCVTHIGTDGAGHFVKMVHNGIEYADMQVIGEAYDILRRGLGMDAE
EIGDVFEEWNKGDLDSYLIEITAQILHHKDAETGKPFVDMVVDHAGMKGTGTWTVQTGLEFGSPVAAIGEAVFARALSSH
GELREDAQKEGLAGPNKTIDLAGEDEAAFVDDVRKALFASKVVAYAQGLNEIQDGAKEYGWDINLSEVARIWRGGCIIRA
QFLLDRITEAFKGDNPPASLLFDPYFEKIIGESQDAWRRVIVRAVEAGIPTPVFSSSLAYYDGLRSKRLPTALTQSQRDL
FGAHTYGRVDKPGVFHTLWAEEGKPEIEA

Sequences:

>Translated_509_residues
MIPSADALFCDARDDDGTIKRKARHMAEATANIGVIGLAAMGSNLARNLAHHGNTVALFNRHYSRTEKLMNEHGAEGNFV
PAETLEEFAASLKRPRTAIIMVKAGAPTDATIAQLEEVFEPGDIIVDGGNSFFKDTIKREKEVRAKGFHFVGCGVSGGEE
GALNGPSLMPGGTVESWKTLGPILESIAAKVNGEPCVTHIGTDGAGHFVKMVHNGIEYADMQVIGEAYDILRRGLGMDAE
EIGDVFEEWNKGDLDSYLIEITAQILHHKDAETGKPFVDMVVDHAGMKGTGTWTVQTGLEFGSPVAAIGEAVFARALSSH
GELREDAQKEGLAGPNKTIDLAGEDEAAFVDDVRKALFASKVVAYAQGLNEIQDGAKEYGWDINLSEVARIWRGGCIIRA
QFLLDRITEAFKGDNPPASLLFDPYFEKIIGESQDAWRRVIVRAVEAGIPTPVFSSSLAYYDGLRSKRLPTALTQSQRDL
FGAHTYGRVDKPGVFHTLWAEEGKPEIEA
>Mature_509_residues
MIPSADALFCDARDDDGTIKRKARHMAEATANIGVIGLAAMGSNLARNLAHHGNTVALFNRHYSRTEKLMNEHGAEGNFV
PAETLEEFAASLKRPRTAIIMVKAGAPTDATIAQLEEVFEPGDIIVDGGNSFFKDTIKREKEVRAKGFHFVGCGVSGGEE
GALNGPSLMPGGTVESWKTLGPILESIAAKVNGEPCVTHIGTDGAGHFVKMVHNGIEYADMQVIGEAYDILRRGLGMDAE
EIGDVFEEWNKGDLDSYLIEITAQILHHKDAETGKPFVDMVVDHAGMKGTGTWTVQTGLEFGSPVAAIGEAVFARALSSH
GELREDAQKEGLAGPNKTIDLAGEDEAAFVDDVRKALFASKVVAYAQGLNEIQDGAKEYGWDINLSEVARIWRGGCIIRA
QFLLDRITEAFKGDNPPASLLFDPYFEKIIGESQDAWRRVIVRAVEAGIPTPVFSSSLAYYDGLRSKRLPTALTQSQRDL
FGAHTYGRVDKPGVFHTLWAEEGKPEIEA

Specific function: Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH [H]

COG id: COG0362

COG function: function code G; 6-phosphogluconate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 6-phosphogluconate dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI40068518, Length=477, Percent_Identity=49.475890985325, Blast_Score=441, Evalue=1e-124,
Organism=Escherichia coli, GI1788341, Length=469, Percent_Identity=52.0255863539446, Blast_Score=498, Evalue=1e-142,
Organism=Caenorhabditis elegans, GI17542558, Length=476, Percent_Identity=48.7394957983193, Blast_Score=469, Evalue=1e-132,
Organism=Saccharomyces cerevisiae, GI6321695, Length=461, Percent_Identity=49.8915401301518, Blast_Score=459, Evalue=1e-130,
Organism=Saccharomyces cerevisiae, GI6321977, Length=457, Percent_Identity=50.7658643326039, Blast_Score=438, Evalue=1e-123,
Organism=Drosophila melanogaster, GI24639279, Length=475, Percent_Identity=45.2631578947368, Blast_Score=399, Evalue=1e-111,
Organism=Drosophila melanogaster, GI24655230, Length=219, Percent_Identity=28.7671232876712, Blast_Score=69, Evalue=1e-11,
Organism=Drosophila melanogaster, GI19922568, Length=219, Percent_Identity=28.7671232876712, Blast_Score=69, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008927
- InterPro:   IPR006114
- InterPro:   IPR006113
- InterPro:   IPR006115
- InterPro:   IPR006184
- InterPro:   IPR013328
- InterPro:   IPR012284
- InterPro:   IPR016040
- InterPro:   IPR006183 [H]

Pfam domain/function: PF00393 6PGD; PF03446 NAD_binding_2 [H]

EC number: =1.1.1.44 [H]

Molecular weight: Translated: 55128; Mature: 55128

Theoretical pI: Translated: 4.88; Mature: 4.88

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIPSADALFCDARDDDGTIKRKARHMAEATANIGVIGLAAMGSNLARNLAHHGNTVALFN
CCCCCCEEEECCCCCCCHHHHHHHHHHHHHHCCCEEEHHHHHHHHHHHHHHCCCEEEEEH
RHYSRTEKLMNEHGAEGNFVPAETLEEFAASLKRPRTAIIMVKAGAPTDATIAQLEEVFE
HHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCEEEEEEECCCCCCHHHHHHHHHCC
PGDIIVDGGNSFFKDTIKREKEVRAKGFHFVGCGVSGGEEGALNGPSLMPGGTVESWKTL
CCCEEEECCCHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCCCCCCCCCCCCCHHHHHHH
GPILESIAAKVNGEPCVTHIGTDGAGHFVKMVHNGIEYADMQVIGEAYDILRRGLGMDAE
HHHHHHHHHHCCCCCCEEECCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCHH
EIGDVFEEWNKGDLDSYLIEITAQILHHKDAETGKPFVDMVVDHAGMKGTGTWTVQTGLE
HHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCCCCEEEECCCC
FGSPVAAIGEAVFARALSSHGELREDAQKEGLAGPNKTIDLAGEDEAAFVDDVRKALFAS
CCCHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCEEEECCCCCHHHHHHHHHHHHHH
KVVAYAQGLNEIQDGAKEYGWDINLSEVARIWRGGCIIRAQFLLDRITEAFKGDNPPASL
HHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCHHH
LFDPYFEKIIGESQDAWRRVIVRAVEAGIPTPVFSSSLAYYDGLRSKRLPTALTQSQRDL
EECHHHHHHHCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHH
FGAHTYGRVDKPGVFHTLWAEEGKPEIEA
HHCCCCCCCCCCCCEEEEECCCCCCCCCC
>Mature Secondary Structure
MIPSADALFCDARDDDGTIKRKARHMAEATANIGVIGLAAMGSNLARNLAHHGNTVALFN
CCCCCCEEEECCCCCCCHHHHHHHHHHHHHHCCCEEEHHHHHHHHHHHHHHCCCEEEEEH
RHYSRTEKLMNEHGAEGNFVPAETLEEFAASLKRPRTAIIMVKAGAPTDATIAQLEEVFE
HHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCEEEEEEECCCCCCHHHHHHHHHCC
PGDIIVDGGNSFFKDTIKREKEVRAKGFHFVGCGVSGGEEGALNGPSLMPGGTVESWKTL
CCCEEEECCCHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCCCCCCCCCCCCCHHHHHHH
GPILESIAAKVNGEPCVTHIGTDGAGHFVKMVHNGIEYADMQVIGEAYDILRRGLGMDAE
HHHHHHHHHHCCCCCCEEECCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCHH
EIGDVFEEWNKGDLDSYLIEITAQILHHKDAETGKPFVDMVVDHAGMKGTGTWTVQTGLE
HHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCCCCEEEECCCC
FGSPVAAIGEAVFARALSSHGELREDAQKEGLAGPNKTIDLAGEDEAAFVDDVRKALFAS
CCCHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCEEEECCCCCHHHHHHHHHHHHHH
KVVAYAQGLNEIQDGAKEYGWDINLSEVARIWRGGCIIRAQFLLDRITEAFKGDNPPASL
HHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCHHH
LFDPYFEKIIGESQDAWRRVIVRAVEAGIPTPVFSSSLAYYDGLRSKRLPTALTQSQRDL
EECHHHHHHHCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHH
FGAHTYGRVDKPGVFHTLWAEEGKPEIEA
HHCCCCCCCCCCCCEEEEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8969508; 9384377; 10568751; 9298659 [H]