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The map label for this gene is pheA [H]

Identifier: 213158677

GI number: 213158677

Start: 2719658

End: 2720767

Strand: Reverse

Name: pheA [H]

Synonym: AB57_2631

Alternate gene names: 213158677

Gene position: 2720767-2719658 (Counterclockwise)

Preceding gene: 213158679

Following gene: 213158676

Centisome position: 67.17

GC content: 40.0

Gene sequence:

>1110_bases
ATGATCAACGATGATCAAAACAAAACGACTTCTCTTAGTTTAGAACAAATTCGCGAAGATATTGATAGCGTAGATCAACA
GATTCAAGAGTTATTAAATCGCCGCGCAAGCCTTGCTGAAGCTGTTGCGAAAGCTAAATTTGCTTCTGAAGAGAATCCTT
TGTTTTATCGTCCTGAACGTGAAGCACAAGTTTTACGTAAAGTTATGGAGCGCAATCAAGGGCCTTTATCTGACGTAACA
ATGGCCCGTTTGTTCCGTGAAATTATGTCTGCTTGCCTTGCTTTAGAAGCTCCGCAAAGTATTGCATTTTTAGGCCCAGA
AGGTACTTTTACTCAATCTGCCGTACTTAAACATTTTGGTAAAGATGCGGTTGTCCGTCCGCTACCAACTATTGATGAAG
TATTCCGTGAAGTGGAAGCGGGTAGTGCGCATTATGGTGTAGTTCCGGTTGAAAACTCATCTGAAGGTATCGTAAACCAT
ACTTTAGATTGTTTTAAAACTTCGAATTTAAATGTGATTGGTGAAGTTGAATTGCGTATTCATCATCAATTCCTTGTTTC
TGAAAATACACGTAAAGACAGTATTAAGCAGATTTATGCGCATCAGCAAACTTTGGCTCAATGTCGTCAGTGGTTAGACG
CACATTATCCGGGTGTTGAGCGTGTTGCCTTAAACTCAAATGCAGAAGCTGCACGCCGTATTCGCAATGAATGGCATTCA
GCGGCGATTGCGTCCGATATTGCAGCAGGTATGTATAACCTTGAAATCTTGCATAGTAATATTGAAGATAATCCAGAAAA
TACCACTCGCTTCTTAGTGATTGGCCGTGAAAAAATTCCACAAAGTGGCAATGACAAAACTTCATTATTAATTTCAGCGC
ATGACCGTGCAGGCGCTTTATTAGAAATTTTAGCGCCGTTTGCAAAACATAATATTAGCTTAACGAGCATTGAGACCCGT
CCAGCATTACCTGAAAAATGGGCATATGTATTCTTTATTGACTTAGAAGGTCATATCGATCAGGAAAATGTGGCTGCGGC
AATCAATGAGATTCGTCCAATGGTAAAAGAACTTCGTATTTTAGGTTCTTATCCTGCTGCTGTTCTTTAA

Upstream 100 bases:

>100_bases
ATTAATGAAAAAAGCCCATACACCCATATTGCCTAACAAATCAAAGCCGACTATTGTTATACTCTCGTTTAAAAGATGAT
TTTGCTGAGGCTGCCTTCCA

Downstream 100 bases:

>100_bases
TCACTCATGTTGGAATAATGACATGTATCAAGATGGGCATGTCATTATGCTTAAAAACAAATTGCTCAAAGGTTTAAATC
ACTTTGAGCAAAAGTAAAGT

Product: chorismate mutase

Products: NA

Alternate protein names: Chorismate mutase; CM; Prephenate dehydratase; PDT [H]

Number of amino acids: Translated: 369; Mature: 369

Protein sequence:

>369_residues
MINDDQNKTTSLSLEQIREDIDSVDQQIQELLNRRASLAEAVAKAKFASEENPLFYRPEREAQVLRKVMERNQGPLSDVT
MARLFREIMSACLALEAPQSIAFLGPEGTFTQSAVLKHFGKDAVVRPLPTIDEVFREVEAGSAHYGVVPVENSSEGIVNH
TLDCFKTSNLNVIGEVELRIHHQFLVSENTRKDSIKQIYAHQQTLAQCRQWLDAHYPGVERVALNSNAEAARRIRNEWHS
AAIASDIAAGMYNLEILHSNIEDNPENTTRFLVIGREKIPQSGNDKTSLLISAHDRAGALLEILAPFAKHNISLTSIETR
PALPEKWAYVFFIDLEGHIDQENVAAAINEIRPMVKELRILGSYPAAVL

Sequences:

>Translated_369_residues
MINDDQNKTTSLSLEQIREDIDSVDQQIQELLNRRASLAEAVAKAKFASEENPLFYRPEREAQVLRKVMERNQGPLSDVT
MARLFREIMSACLALEAPQSIAFLGPEGTFTQSAVLKHFGKDAVVRPLPTIDEVFREVEAGSAHYGVVPVENSSEGIVNH
TLDCFKTSNLNVIGEVELRIHHQFLVSENTRKDSIKQIYAHQQTLAQCRQWLDAHYPGVERVALNSNAEAARRIRNEWHS
AAIASDIAAGMYNLEILHSNIEDNPENTTRFLVIGREKIPQSGNDKTSLLISAHDRAGALLEILAPFAKHNISLTSIETR
PALPEKWAYVFFIDLEGHIDQENVAAAINEIRPMVKELRILGSYPAAVL
>Mature_369_residues
MINDDQNKTTSLSLEQIREDIDSVDQQIQELLNRRASLAEAVAKAKFASEENPLFYRPEREAQVLRKVMERNQGPLSDVT
MARLFREIMSACLALEAPQSIAFLGPEGTFTQSAVLKHFGKDAVVRPLPTIDEVFREVEAGSAHYGVVPVENSSEGIVNH
TLDCFKTSNLNVIGEVELRIHHQFLVSENTRKDSIKQIYAHQQTLAQCRQWLDAHYPGVERVALNSNAEAARRIRNEWHS
AAIASDIAAGMYNLEILHSNIEDNPENTTRFLVIGREKIPQSGNDKTSLLISAHDRAGALLEILAPFAKHNISLTSIETR
PALPEKWAYVFFIDLEGHIDQENVAAAINEIRPMVKELRILGSYPAAVL

Specific function: L-phenylalanine biosynthesis. [C]

COG id: COG0077

COG function: function code E; Prephenate dehydratase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 prephenate dehydratase domain [H]

Homologues:

Organism=Escherichia coli, GI1788951, Length=376, Percent_Identity=30.5851063829787, Blast_Score=175, Evalue=5e-45,
Organism=Saccharomyces cerevisiae, GI6324013, Length=320, Percent_Identity=27.5, Blast_Score=87, Evalue=4e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002912
- InterPro:   IPR008242
- InterPro:   IPR002701
- InterPro:   IPR020822
- InterPro:   IPR010957
- InterPro:   IPR001086
- InterPro:   IPR018528 [H]

Pfam domain/function: PF01842 ACT; PF01817 CM_2; PF00800 PDT [H]

EC number: =5.4.99.5; =4.2.1.51 [H]

Molecular weight: Translated: 41293; Mature: 41293

Theoretical pI: Translated: 5.44; Mature: 5.44

Prosite motif: PS00857 PREPHENATE_DEHYDR_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MINDDQNKTTSLSLEQIREDIDSVDQQIQELLNRRASLAEAVAKAKFASEENPLFYRPER
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCH
EAQVLRKVMERNQGPLSDVTMARLFREIMSACLALEAPQSIAFLGPEGTFTQSAVLKHFG
HHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCHHHHHHHHCC
KDAVVRPLPTIDEVFREVEAGSAHYGVVPVENSSEGIVNHTLDCFKTSNLNVIGEVELRI
CCCCCCCCCCHHHHHHHHHCCCCCCCEEECCCCCCCHHHHHHHHHCCCCCCEEEEEEEEE
HHQFLVSENTRKDSIKQIYAHQQTLAQCRQWLDAHYPGVERVALNSNAEAARRIRNEWHS
EEHHEECCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCHHHHHHHHHHHHH
AAIASDIAAGMYNLEILHSNIEDNPENTTRFLVIGREKIPQSGNDKTSLLISAHDRAGAL
HHHHHHHHHHHHHHHEEECCCCCCCCCCEEEEEEEHHHCCCCCCCCEEEEEEECCCHHHH
LEILAPFAKHNISLTSIETRPALPEKWAYVFFIDLEGHIDQENVAAAINEIRPMVKELRI
HHHHHHHHHCCCEEEEECCCCCCCCCEEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHH
LGSYPAAVL
HCCCCCCCC
>Mature Secondary Structure
MINDDQNKTTSLSLEQIREDIDSVDQQIQELLNRRASLAEAVAKAKFASEENPLFYRPER
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCH
EAQVLRKVMERNQGPLSDVTMARLFREIMSACLALEAPQSIAFLGPEGTFTQSAVLKHFG
HHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCHHHHHHHHCC
KDAVVRPLPTIDEVFREVEAGSAHYGVVPVENSSEGIVNHTLDCFKTSNLNVIGEVELRI
CCCCCCCCCCHHHHHHHHHCCCCCCCEEECCCCCCCHHHHHHHHHCCCCCCEEEEEEEEE
HHQFLVSENTRKDSIKQIYAHQQTLAQCRQWLDAHYPGVERVALNSNAEAARRIRNEWHS
EEHHEECCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCHHHHHHHHHHHHH
AAIASDIAAGMYNLEILHSNIEDNPENTTRFLVIGREKIPQSGNDKTSLLISAHDRAGAL
HHHHHHHHHHHHHHHEEECCCCCCCCCCEEEEEEEHHHCCCCCCCCEEEEEEECCCHHHH
LEILAPFAKHNISLTSIETRPALPEKWAYVFFIDLEGHIDQENVAAAINEIRPMVKELRI
HHHHHHHHHCCCEEEEECCCCCCCCCEEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHH
LGSYPAAVL
HCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]