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The map label for this gene is mmgC [H]

Identifier: 213158679

GI number: 213158679

Start: 2721940

End: 2723085

Strand: Reverse

Name: mmgC [H]

Synonym: AB57_2633

Alternate gene names: 213158679

Gene position: 2723085-2721940 (Counterclockwise)

Preceding gene: 213158680

Following gene: 213158677

Centisome position: 67.23

GC content: 39.88

Gene sequence:

>1146_bases
ATGTTGGCATATGATGCAGATTTAGAATTATTCCGTGATAATTTTAAACGTTTTATGAATGAGCATATTGCTCCACATTA
TGACCAATGGGAACGTGAAGGAATTATGCCACGTTCAGTTTGGTCTCAACTGGGCGAAAATGGTTTTTTATGTGTGGATG
TCCCAGAAGAATATGGTGGTTATGGCGTCCCAACGTATTATTCATTAATGTTAGTTGAAGAATCGGCTCGTGCTGGATTT
TGCGCATTATCAACTGCTATTTCTTGTCACTCTGAGATTGCAGCGCCTTATATTTTACATATTGGGACTGAAGAACAAAA
ACAATACTGGTTACCGAAAATGGTAACAGGTGAAGTAGTCGGAGCAATTGGTATGACAGAACCGGGTGCCGGTTCAGACT
TACAGTCAATGCGTACCAGTGCCATTTTGCAAGATGACCATTATTTGCTAAATGGTTCTAAAACGTTTATTTCAAATGGA
CAACATGCTGACCTTGTAGTGCTTGCCGTAAAAACCGATCCGCAAGCGCGTGCGAAAGGTGTATCTTTATTATTGGTGGA
TACTCACTTAGAAGGTTTCAAAAAAGGAACTAACCTCGACAAAATCGGATTGCATTCTCAAGACACATCTGAGCTATTTT
TTGACAATGTTAAGGTTCCTAAAAACCAGTTACTCGGCCAAGCTGGACAAGGTTTTGCTTATTTAATGCAAGAATTACCG
CGCGAACGTACGGCTATCGCATCGACAGCGGTTGGCGCTATTCGTGGTGCAATTGATTTGGCAACCGCTTATGTAAAAGA
ACGTCATGCATTTGGTCAACCTATTTCACAGTTCCAAAATACTCGTTTTGTTTTAGCACAAGCAAAAATTGATGAGCTTG
CGACAACAGCTTTCTATGAGCGAAATGTTGCTTTATATCAAGAAGGTAAACTTGATGTTGAGACGGCTGCAGCACTGAAA
AGTTTTAGTACAGATATGCAAATGAAGGTGGCGGATAACCTATTACAACTATTTGGTGGTTATGGTTATATGACTGAATA
TCCAATTTCACGCTTCTTTGTAGATGCCCGTATTCAACGTATTTACGGCGGTACAAATGAAATTATGAAAGAAATCGTAG
CACGTGGATTAATCGGCAAAGCTTAA

Upstream 100 bases:

>100_bases
ACAGTTTAAATGAGCAGCTAAGCCATGACAGTTGTGTAAAAAATGATTAGCATGCACAGCAATGAGATTCGATAAAACAA
TAAAGCCGAAGGAAAATATT

Downstream 100 bases:

>100_bases
TAATAGTTTCAAAAAAAGCCTACCTTTGAGTAGGCTTTTTTATTATTTAGCTGTTTTCTGCGATGGTTCATCGAATAAAG
ATTTACAGCTTTCTAGATTT

Product: acyl-CoA dehydrogenase

Products: 2,3-dehydroacyl-CoA; reduced acceptor

Alternate protein names: NA

Number of amino acids: Translated: 381; Mature: 381

Protein sequence:

>381_residues
MLAYDADLELFRDNFKRFMNEHIAPHYDQWEREGIMPRSVWSQLGENGFLCVDVPEEYGGYGVPTYYSLMLVEESARAGF
CALSTAISCHSEIAAPYILHIGTEEQKQYWLPKMVTGEVVGAIGMTEPGAGSDLQSMRTSAILQDDHYLLNGSKTFISNG
QHADLVVLAVKTDPQARAKGVSLLLVDTHLEGFKKGTNLDKIGLHSQDTSELFFDNVKVPKNQLLGQAGQGFAYLMQELP
RERTAIASTAVGAIRGAIDLATAYVKERHAFGQPISQFQNTRFVLAQAKIDELATTAFYERNVALYQEGKLDVETAAALK
SFSTDMQMKVADNLLQLFGGYGYMTEYPISRFFVDARIQRIYGGTNEIMKEIVARGLIGKA

Sequences:

>Translated_381_residues
MLAYDADLELFRDNFKRFMNEHIAPHYDQWEREGIMPRSVWSQLGENGFLCVDVPEEYGGYGVPTYYSLMLVEESARAGF
CALSTAISCHSEIAAPYILHIGTEEQKQYWLPKMVTGEVVGAIGMTEPGAGSDLQSMRTSAILQDDHYLLNGSKTFISNG
QHADLVVLAVKTDPQARAKGVSLLLVDTHLEGFKKGTNLDKIGLHSQDTSELFFDNVKVPKNQLLGQAGQGFAYLMQELP
RERTAIASTAVGAIRGAIDLATAYVKERHAFGQPISQFQNTRFVLAQAKIDELATTAFYERNVALYQEGKLDVETAAALK
SFSTDMQMKVADNLLQLFGGYGYMTEYPISRFFVDARIQRIYGGTNEIMKEIVARGLIGKA
>Mature_381_residues
MLAYDADLELFRDNFKRFMNEHIAPHYDQWEREGIMPRSVWSQLGENGFLCVDVPEEYGGYGVPTYYSLMLVEESARAGF
CALSTAISCHSEIAAPYILHIGTEEQKQYWLPKMVTGEVVGAIGMTEPGAGSDLQSMRTSAILQDDHYLLNGSKTFISNG
QHADLVVLAVKTDPQARAKGVSLLLVDTHLEGFKKGTNLDKIGLHSQDTSELFFDNVKVPKNQLLGQAGQGFAYLMQELP
RERTAIASTAVGAIRGAIDLATAYVKERHAFGQPISQFQNTRFVLAQAKIDELATTAFYERNVALYQEGKLDVETAAALK
SFSTDMQMKVADNLLQLFGGYGYMTEYPISRFFVDARIQRIYGGTNEIMKEIVARGLIGKA

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4501857, Length=377, Percent_Identity=41.9098143236074, Blast_Score=323, Evalue=1e-88,
Organism=Homo sapiens, GI226958412, Length=374, Percent_Identity=33.6898395721925, Blast_Score=229, Evalue=3e-60,
Organism=Homo sapiens, GI226958414, Length=342, Percent_Identity=34.5029239766082, Blast_Score=216, Evalue=2e-56,
Organism=Homo sapiens, GI4557233, Length=370, Percent_Identity=32.1621621621622, Blast_Score=215, Evalue=7e-56,
Organism=Homo sapiens, GI4501859, Length=368, Percent_Identity=32.3369565217391, Blast_Score=207, Evalue=9e-54,
Organism=Homo sapiens, GI4557231, Length=374, Percent_Identity=32.8877005347594, Blast_Score=198, Evalue=6e-51,
Organism=Homo sapiens, GI187960098, Length=374, Percent_Identity=32.8877005347594, Blast_Score=198, Evalue=7e-51,
Organism=Homo sapiens, GI7656849, Length=364, Percent_Identity=33.2417582417582, Blast_Score=197, Evalue=1e-50,
Organism=Homo sapiens, GI21361497, Length=382, Percent_Identity=31.6753926701571, Blast_Score=190, Evalue=2e-48,
Organism=Homo sapiens, GI4557235, Length=346, Percent_Identity=35.2601156069364, Blast_Score=185, Evalue=7e-47,
Organism=Homo sapiens, GI76496475, Length=350, Percent_Identity=34.8571428571429, Blast_Score=185, Evalue=8e-47,
Organism=Homo sapiens, GI4503943, Length=381, Percent_Identity=28.8713910761155, Blast_Score=131, Evalue=1e-30,
Organism=Homo sapiens, GI7669494, Length=357, Percent_Identity=28.8515406162465, Blast_Score=120, Evalue=1e-27,
Organism=Homo sapiens, GI48976061, Length=291, Percent_Identity=30.5841924398625, Blast_Score=115, Evalue=6e-26,
Organism=Homo sapiens, GI211971008, Length=291, Percent_Identity=30.5841924398625, Blast_Score=115, Evalue=7e-26,
Organism=Homo sapiens, GI38505218, Length=291, Percent_Identity=25.085910652921, Blast_Score=81, Evalue=2e-15,
Organism=Escherichia coli, GI87081958, Length=360, Percent_Identity=32.2222222222222, Blast_Score=165, Evalue=4e-42,
Organism=Escherichia coli, GI1786223, Length=389, Percent_Identity=27.5064267352185, Blast_Score=142, Evalue=5e-35,
Organism=Escherichia coli, GI87082384, Length=278, Percent_Identity=28.4172661870504, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI87081702, Length=272, Percent_Identity=27.2058823529412, Blast_Score=72, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI17538396, Length=376, Percent_Identity=34.3085106382979, Blast_Score=233, Evalue=2e-61,
Organism=Caenorhabditis elegans, GI17534899, Length=364, Percent_Identity=33.5164835164835, Blast_Score=214, Evalue=5e-56,
Organism=Caenorhabditis elegans, GI17508101, Length=360, Percent_Identity=31.1111111111111, Blast_Score=213, Evalue=2e-55,
Organism=Caenorhabditis elegans, GI17570075, Length=379, Percent_Identity=32.1899736147757, Blast_Score=210, Evalue=1e-54,
Organism=Caenorhabditis elegans, GI17533517, Length=381, Percent_Identity=33.0708661417323, Blast_Score=205, Evalue=4e-53,
Organism=Caenorhabditis elegans, GI17506239, Length=366, Percent_Identity=29.7814207650273, Blast_Score=201, Evalue=6e-52,
Organism=Caenorhabditis elegans, GI17551932, Length=377, Percent_Identity=30.5039787798408, Blast_Score=192, Evalue=2e-49,
Organism=Caenorhabditis elegans, GI17505929, Length=377, Percent_Identity=29.4429708222812, Blast_Score=189, Evalue=3e-48,
Organism=Caenorhabditis elegans, GI17569725, Length=373, Percent_Identity=29.7587131367292, Blast_Score=188, Evalue=4e-48,
Organism=Caenorhabditis elegans, GI71990804, Length=294, Percent_Identity=31.9727891156463, Blast_Score=172, Evalue=3e-43,
Organism=Caenorhabditis elegans, GI71985184, Length=352, Percent_Identity=31.8181818181818, Blast_Score=166, Evalue=2e-41,
Organism=Caenorhabditis elegans, GI32563615, Length=228, Percent_Identity=32.8947368421053, Blast_Score=149, Evalue=2e-36,
Organism=Caenorhabditis elegans, GI71985192, Length=284, Percent_Identity=32.3943661971831, Blast_Score=137, Evalue=1e-32,
Organism=Caenorhabditis elegans, GI71982178, Length=266, Percent_Identity=28.5714285714286, Blast_Score=134, Evalue=1e-31,
Organism=Caenorhabditis elegans, GI17534353, Length=367, Percent_Identity=28.0653950953678, Blast_Score=126, Evalue=2e-29,
Organism=Caenorhabditis elegans, GI17562446, Length=292, Percent_Identity=28.4246575342466, Blast_Score=105, Evalue=4e-23,
Organism=Caenorhabditis elegans, GI17531909, Length=240, Percent_Identity=24.5833333333333, Blast_Score=89, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI86563383, Length=278, Percent_Identity=28.0575539568345, Blast_Score=69, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI86563381, Length=278, Percent_Identity=28.0575539568345, Blast_Score=69, Evalue=3e-12,
Organism=Drosophila melanogaster, GI21355753, Length=389, Percent_Identity=34.1902313624679, Blast_Score=204, Evalue=7e-53,
Organism=Drosophila melanogaster, GI21356377, Length=370, Percent_Identity=30.5405405405405, Blast_Score=204, Evalue=9e-53,
Organism=Drosophila melanogaster, GI24646207, Length=375, Percent_Identity=31.4666666666667, Blast_Score=187, Evalue=7e-48,
Organism=Drosophila melanogaster, GI24660351, Length=365, Percent_Identity=29.8630136986301, Blast_Score=184, Evalue=6e-47,
Organism=Drosophila melanogaster, GI24666513, Length=372, Percent_Identity=28.7634408602151, Blast_Score=180, Evalue=1e-45,
Organism=Drosophila melanogaster, GI281363737, Length=373, Percent_Identity=31.9034852546917, Blast_Score=171, Evalue=1e-42,
Organism=Drosophila melanogaster, GI19920834, Length=378, Percent_Identity=30.4232804232804, Blast_Score=146, Evalue=2e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: 1.3.99.3

Molecular weight: Translated: 42257; Mature: 42257

Theoretical pI: Translated: 5.27; Mature: 5.27

Prosite motif: PS00072 ACYL_COA_DH_1 ; PS00073 ACYL_COA_DH_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLAYDADLELFRDNFKRFMNEHIAPHYDQWEREGIMPRSVWSQLGENGFLCVDVPEEYGG
CCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHCCCCHHHHHHHHCCCCEEEEECCHHHCC
YGVPTYYSLMLVEESARAGFCALSTAISCHSEIAAPYILHIGTEEQKQYWLPKMVTGEVV
CCCCHHEEEEEEECCCCCCHHHHHHHHHHHHHHCCCEEEEECCCHHHHHCCCCHHHHHHH
GAIGMTEPGAGSDLQSMRTSAILQDDHYLLNGSKTFISNGQHADLVVLAVKTDPQARAKG
HHCCCCCCCCCCHHHHHHHHHHCCCCCEEECCCCCEECCCCCCEEEEEEEECCCHHHHCC
VSLLLVDTHLEGFKKGTNLDKIGLHSQDTSELFFDNVKVPKNQLLGQAGQGFAYLMQELP
CEEEEEECCHHHHHCCCCCCCCCCCCCCCHHHHHCCCCCCHHHHHCCCCCCHHHHHHHCC
RERTAIASTAVGAIRGAIDLATAYVKERHAFGQPISQFQNTRFVLAQAKIDELATTAFYE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCEEEEEHHHHHHHHHHHHHH
RNVALYQEGKLDVETAAALKSFSTDMQMKVADNLLQLFGGYGYMTEYPISRFFVDARIQR
CCEEEEECCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHH
IYGGTNEIMKEIVARGLIGKA
HHCCHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MLAYDADLELFRDNFKRFMNEHIAPHYDQWEREGIMPRSVWSQLGENGFLCVDVPEEYGG
CCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHCCCCHHHHHHHHCCCCEEEEECCHHHCC
YGVPTYYSLMLVEESARAGFCALSTAISCHSEIAAPYILHIGTEEQKQYWLPKMVTGEVV
CCCCHHEEEEEEECCCCCCHHHHHHHHHHHHHHCCCEEEEECCCHHHHHCCCCHHHHHHH
GAIGMTEPGAGSDLQSMRTSAILQDDHYLLNGSKTFISNGQHADLVVLAVKTDPQARAKG
HHCCCCCCCCCCHHHHHHHHHHCCCCCEEECCCCCEECCCCCCEEEEEEEECCCHHHHCC
VSLLLVDTHLEGFKKGTNLDKIGLHSQDTSELFFDNVKVPKNQLLGQAGQGFAYLMQELP
CEEEEEECCHHHHHCCCCCCCCCCCCCCCHHHHHCCCCCCHHHHHCCCCCCHHHHHHHCC
RERTAIASTAVGAIRGAIDLATAYVKERHAFGQPISQFQNTRFVLAQAKIDELATTAFYE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCEEEEEHHHHHHHHHHHHHH
RNVALYQEGKLDVETAAALKSFSTDMQMKVADNLLQLFGGYGYMTEYPISRFFVDARIQR
CCEEEEECCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHH
IYGGTNEIMKEIVARGLIGKA
HHCCHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: acyl-CoA; acceptor

Specific reaction: acyl-CoA + acceptor = 2,3-dehydroacyl-CoA + reduced acceptor

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8759838; 8969508; 9384377 [H]