Click here to switch to the map view.

The map label for this gene is aroA [H]

Identifier: 213158676

GI number: 213158676

Start: 2717304

End: 2719574

Strand: Reverse

Name: aroA [H]

Synonym: AB57_2630

Alternate gene names: 213158676

Gene position: 2719574-2717304 (Counterclockwise)

Preceding gene: 213158677

Following gene: 213158675

Centisome position: 67.14

GC content: 42.58

Gene sequence:

>2271_bases
TTGAGCAAAAGTAAAGTTGAAGTTATGTCACAACCCCTATTTAAAAAAGTTGCATTTATTGGTTTAGGACTCATTGGGTC
GAGTTTGGCTCGCGTTATTGTTGCAGAAAAGTTGGCGACAACTATTGTGGCATCTACACGTTCACAGAAAACTTTAGAAG
ATGCAAAATCACTTGGCTTAATACAAGAAGGGTTTTCCGATCCTGTAGAAGCTGTGAAAGGGGCGGATTTAGTTGTTTTA
GCCTTGCCAGTGCGTGCCACTCAAAAAGTGCTTGAGCAAATTAAACCTTATTTGTCTGAAACCACAATTGTAACTGACGT
GGGAAGTACAAAAGGTAATGTCGTAGATGCAGCAAAAGCTGTATTTGGTGAAGATTTACCAGCAGGGTTTGTTCCCGGGC
ATCCGATTGCGGGAAGTGAACACACGGGTGTCCACGCAGGTAAGGTCGATCTCTTTGCAAATCACAAAGTGATTTTGACG
CCATTACCAACCAGTGCAGAATGGGCAGTTGAGAAACTGATTCAACTTTGGTCAGCTGCTAAAGCCGAAGTGATATGTAT
GGATGTTGCCAAACATGATGAAGTTTTGGCGCATACCAGTCATTTACCGCACTTAATGGCATTTAATCTGGTCGAGCAAC
TTGCAAACCGTGAAGATAATCTTGATATTTTCCGTTATGCAGCGGGTGGTTTTCGTGACTTTTCACGAATTGCTGCCAGT
GATCCTCAAATGTGGCATGACATTTTCTTTGCCAATAAAACAGCCATATTAAATGCTGTAGATGGCTTCGAGAAACAACT
TACCGTACTTAGAAAATTGATTGAAAACGAAGATTCTCATGCATTAATGGGTTTACTCGGCCATGCTCAGGCAGCACGTC
AGCATTTCAATCATATGTTAGCCAAAAAACCTTTAATGGAGAAAAATAAGGTGACACAGCAATTCAGTATCTTACCGGGA
AATAAGGCTTTTAAAGGTAAATTTACCGTACCGGGTGACAAATCTGTGTCACATCGCTCCATTATGTTTGGTGCTATTGC
AGAAGGCACTACGCATGTAACAGGCTTCCTTGAAGGTGAAGATGCTTTAGCAACTTTACAAGCTTTCCGTGATATGGGTG
TAAGCATTGAAGGCCCTAAAAATGGTGAAGTGACCATTCATGGCGTGGGCATGCATGGCTTAAAAGCACCAGCAAGTGCG
TTGTATATGGGTAATTCTGGAACAAGCATGCGTTTGCTTTCAGGTATGCTTTCTGCACAAAAGTTTGATTCTGTTATGAC
AGGTGATGCGTCACTTTCTAAACGTCCAATGGAGCGTATTGCTAAACCATTACGTTTAATGGGTGCGCAAATCCAAACGA
CAGGTGAGAAAGGTACACCACCTGTAAGCATTACTGGTGGTCAGCAATTAAAAGGTATTCAATACGATTTACCTATGGCA
TCTGCTCAGGTGAAGTCGGGTATTTTACTTGCCGGTTTATGGGCTGAAGGTGAAACTTCGGTAACTGAACCGGAACCAAC
ACGTGATCATACAGAGCGTATGCTTCGTGCATTTGGCTATGATGTTAAAACTGAAGGCAATAAAATTTCCCTTGTGGGCG
GCGGTAAGTTAGTGGGTACTAATATTCAAGTACCATCTGATATTTCATCTGCTGCTTTCTTCATGGTGGGCGCTGCAATC
ACTGAAGGCGCAGACGTTGTTCTGGAAGCTGTAGGTATTAATCCAACACGTACTGGCGTAATTGAAATTTTAAAACAGAT
GGGTGCTGACCTGACTGTTGAAAATGAGCGTATCGCTGGCGGAGAGCCTATTGCTGATATTCATATTAAAGGTTCACGTA
CCCTTAAAGGCATTCACATGCCTGAAGACCAAGTACCTTTAGCAATTGATGAATTCCCAGCCTTATTTATTGCAGCGGCT
TGTGCTGAAGGCCAAACAGTATTAACAGGTGCAGCAGAGCTTCGCGTGAAAGAATCTGACCGTATTCAAGTTATGGCAGA
TGGCTTAAAAATCATGGGCATTGATTGCACACCTACTGAAGATGGCATCATTATCGAAGGTAAAGGCAAATCTGGTGATT
GGTCACCAATCTTTGCTGGTGGTGAAATTGAATCACATCATGACCACCGTATTGCCATGAGTTTTAGTATGGCAGGTCTT
CGTACTTCTGGTCCGATTACAATTCACGGTACTGAAACTGTTGCTACAAGTTTCCCAACTTTTACTGAGTTGGCGAATCG
TGCAGGCTTAACGATTGAAGTTAGCCAATAA

Upstream 100 bases:

>100_bases
CTGCTGCTGTTCTTTAATCACTCATGTTGGAATAATGACATGTATCAAGATGGGCATGTCATTATGCTTAAAAACAAATT
GCTCAAAGGTTTAAATCACT

Downstream 100 bases:

>100_bases
CTTTTACCTAACACATTTTATAATTGCTAACACAATAGCAACGGCAGCAGCGAGCTAAAGGCTTGGCTGCTGTTTGTTTA
TTGCTTATGCTAAGTGCAGA

Product: bifunctional cyclohexadienyl dehydrogenase/ 3-phosphoshikimate 1-carboxyvinyltransferase

Products: NA

Alternate protein names: 5-enolpyruvylshikimate-3-phosphate synthase; EPSP synthase; EPSPS [H]

Number of amino acids: Translated: 756; Mature: 755

Protein sequence:

>756_residues
MSKSKVEVMSQPLFKKVAFIGLGLIGSSLARVIVAEKLATTIVASTRSQKTLEDAKSLGLIQEGFSDPVEAVKGADLVVL
ALPVRATQKVLEQIKPYLSETTIVTDVGSTKGNVVDAAKAVFGEDLPAGFVPGHPIAGSEHTGVHAGKVDLFANHKVILT
PLPTSAEWAVEKLIQLWSAAKAEVICMDVAKHDEVLAHTSHLPHLMAFNLVEQLANREDNLDIFRYAAGGFRDFSRIAAS
DPQMWHDIFFANKTAILNAVDGFEKQLTVLRKLIENEDSHALMGLLGHAQAARQHFNHMLAKKPLMEKNKVTQQFSILPG
NKAFKGKFTVPGDKSVSHRSIMFGAIAEGTTHVTGFLEGEDALATLQAFRDMGVSIEGPKNGEVTIHGVGMHGLKAPASA
LYMGNSGTSMRLLSGMLSAQKFDSVMTGDASLSKRPMERIAKPLRLMGAQIQTTGEKGTPPVSITGGQQLKGIQYDLPMA
SAQVKSGILLAGLWAEGETSVTEPEPTRDHTERMLRAFGYDVKTEGNKISLVGGGKLVGTNIQVPSDISSAAFFMVGAAI
TEGADVVLEAVGINPTRTGVIEILKQMGADLTVENERIAGGEPIADIHIKGSRTLKGIHMPEDQVPLAIDEFPALFIAAA
CAEGQTVLTGAAELRVKESDRIQVMADGLKIMGIDCTPTEDGIIIEGKGKSGDWSPIFAGGEIESHHDHRIAMSFSMAGL
RTSGPITIHGTETVATSFPTFTELANRAGLTIEVSQ

Sequences:

>Translated_756_residues
MSKSKVEVMSQPLFKKVAFIGLGLIGSSLARVIVAEKLATTIVASTRSQKTLEDAKSLGLIQEGFSDPVEAVKGADLVVL
ALPVRATQKVLEQIKPYLSETTIVTDVGSTKGNVVDAAKAVFGEDLPAGFVPGHPIAGSEHTGVHAGKVDLFANHKVILT
PLPTSAEWAVEKLIQLWSAAKAEVICMDVAKHDEVLAHTSHLPHLMAFNLVEQLANREDNLDIFRYAAGGFRDFSRIAAS
DPQMWHDIFFANKTAILNAVDGFEKQLTVLRKLIENEDSHALMGLLGHAQAARQHFNHMLAKKPLMEKNKVTQQFSILPG
NKAFKGKFTVPGDKSVSHRSIMFGAIAEGTTHVTGFLEGEDALATLQAFRDMGVSIEGPKNGEVTIHGVGMHGLKAPASA
LYMGNSGTSMRLLSGMLSAQKFDSVMTGDASLSKRPMERIAKPLRLMGAQIQTTGEKGTPPVSITGGQQLKGIQYDLPMA
SAQVKSGILLAGLWAEGETSVTEPEPTRDHTERMLRAFGYDVKTEGNKISLVGGGKLVGTNIQVPSDISSAAFFMVGAAI
TEGADVVLEAVGINPTRTGVIEILKQMGADLTVENERIAGGEPIADIHIKGSRTLKGIHMPEDQVPLAIDEFPALFIAAA
CAEGQTVLTGAAELRVKESDRIQVMADGLKIMGIDCTPTEDGIIIEGKGKSGDWSPIFAGGEIESHHDHRIAMSFSMAGL
RTSGPITIHGTETVATSFPTFTELANRAGLTIEVSQ
>Mature_755_residues
SKSKVEVMSQPLFKKVAFIGLGLIGSSLARVIVAEKLATTIVASTRSQKTLEDAKSLGLIQEGFSDPVEAVKGADLVVLA
LPVRATQKVLEQIKPYLSETTIVTDVGSTKGNVVDAAKAVFGEDLPAGFVPGHPIAGSEHTGVHAGKVDLFANHKVILTP
LPTSAEWAVEKLIQLWSAAKAEVICMDVAKHDEVLAHTSHLPHLMAFNLVEQLANREDNLDIFRYAAGGFRDFSRIAASD
PQMWHDIFFANKTAILNAVDGFEKQLTVLRKLIENEDSHALMGLLGHAQAARQHFNHMLAKKPLMEKNKVTQQFSILPGN
KAFKGKFTVPGDKSVSHRSIMFGAIAEGTTHVTGFLEGEDALATLQAFRDMGVSIEGPKNGEVTIHGVGMHGLKAPASAL
YMGNSGTSMRLLSGMLSAQKFDSVMTGDASLSKRPMERIAKPLRLMGAQIQTTGEKGTPPVSITGGQQLKGIQYDLPMAS
AQVKSGILLAGLWAEGETSVTEPEPTRDHTERMLRAFGYDVKTEGNKISLVGGGKLVGTNIQVPSDISSAAFFMVGAAIT
EGADVVLEAVGINPTRTGVIEILKQMGADLTVENERIAGGEPIADIHIKGSRTLKGIHMPEDQVPLAIDEFPALFIAAAC
AEGQTVLTGAAELRVKESDRIQVMADGLKIMGIDCTPTEDGIIIEGKGKSGDWSPIFAGGEIESHHDHRIAMSFSMAGLR
TSGPITIHGTETVATSFPTFTELANRAGLTIEVSQ

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; sixth step. [C]

COG id: COG0128

COG function: function code E; 5-enolpyruvylshikimate-3-phosphate synthase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the EPSP synthase family [H]

Homologues:

Organism=Escherichia coli, GI1787137, Length=436, Percent_Identity=29.8165137614679, Blast_Score=142, Evalue=6e-35,
Organism=Saccharomyces cerevisiae, GI6320332, Length=426, Percent_Identity=29.3427230046948, Blast_Score=135, Evalue=2e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001986
- InterPro:   IPR006264
- InterPro:   IPR023193
- InterPro:   IPR013792 [H]

Pfam domain/function: PF00275 EPSP_synthase [H]

EC number: =2.5.1.19 [H]

Molecular weight: Translated: 80604; Mature: 80472

Theoretical pI: Translated: 6.38; Mature: 6.38

Prosite motif: PS00104 EPSP_SYNTHASE_1 ; PS00885 EPSP_SYNTHASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKSKVEVMSQPLFKKVAFIGLGLIGSSLARVIVAEKLATTIVASTRSQKTLEDAKSLGL
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCH
IQEGFSDPVEAVKGADLVVLALPVRATQKVLEQIKPYLSETTIVTDVGSTKGNVVDAAKA
HHHCCCCHHHHHCCCCEEEEEECCHHHHHHHHHHHHHHCCCEEEEECCCCCCCHHHHHHH
VFGEDLPAGFVPGHPIAGSEHTGVHAGKVDLFANHKVILTPLPTSAEWAVEKLIQLWSAA
HHCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCEEEEEECCCCHHHHHHHHHHHHHCC
KAEVICMDVAKHDEVLAHTSHLPHLMAFNLVEQLANREDNLDIFRYAAGGFRDFSRIAAS
CCEEEEEEHHHCHHHHHHHHCCHHHHHHHHHHHHHCCCCCCEEEEECCCCHHHHHHHHCC
DPQMWHDIFFANKTAILNAVDGFEKQLTVLRKLIENEDSHALMGLLGHAQAARQHFNHML
CCHHHHHHHHCCCHHEEEHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHH
AKKPLMEKNKVTQQFSILPGNKAFKGKFTVPGDKSVSHRSIMFGAIAEGTTHVTGFLEGE
HHCCCHHHHHHHHEEEECCCCCCCCCEEECCCCCCCCCCEEEEEECCCCCEEEEEEECCC
DALATLQAFRDMGVSIEGPKNGEVTIHGVGMHGLKAPASALYMGNSGTSMRLLSGMLSAQ
HHHHHHHHHHHCCCEEECCCCCCEEEEEECCCCCCCCCCEEEECCCCCHHHHHHHHHHHH
KFDSVMTGDASLSKRPMERIAKPLRLMGAQIQTTGEKGTPPVSITGGQQLKGIQYDLPMA
HHHHHHCCCCHHHHHHHHHHHHHHHHHCCEEEECCCCCCCCEEECCCCCCCCEEECCCCC
SAQVKSGILLAGLWAEGETSVTEPEPTRDHTERMLRAFGYDVKTEGNKISLVGGGKLVGT
HHHHHCCEEEEEEECCCCCCCCCCCCCHHHHHHHHHHHCCCEECCCCEEEEEECCEEEEC
NIQVPSDISSAAFFMVGAAITEGADVVLEAVGINPTRTGVIEILKQMGADLTVENERIAG
CEECCCCCHHHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHCCCEEECCCCCCC
GEPIADIHIKGSRTLKGIHMPEDQVPLAIDEFPALFIAAACAEGQTVLTGAAELRVKESD
CCCEEEEEECCCCEEEECCCCCCCCCEEHHHHHHHHHHHHHCCCCEEEECCEEEEECCCC
RIQVMADGLKIMGIDCTPTEDGIIIEGKGKSGDWSPIFAGGEIESHHDHRIAMSFSMAGL
CEEEEECCEEEEEEECCCCCCCEEEECCCCCCCCCEEEECCCCCCCCCCEEEEEEEECCC
RTSGPITIHGTETVATSFPTFTELANRAGLTIEVSQ
CCCCCEEEECCHHHHCCCCCHHHHHHCCCCEEEECC
>Mature Secondary Structure 
SKSKVEVMSQPLFKKVAFIGLGLIGSSLARVIVAEKLATTIVASTRSQKTLEDAKSLGL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCH
IQEGFSDPVEAVKGADLVVLALPVRATQKVLEQIKPYLSETTIVTDVGSTKGNVVDAAKA
HHHCCCCHHHHHCCCCEEEEEECCHHHHHHHHHHHHHHCCCEEEEECCCCCCCHHHHHHH
VFGEDLPAGFVPGHPIAGSEHTGVHAGKVDLFANHKVILTPLPTSAEWAVEKLIQLWSAA
HHCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCEEEEEECCCCHHHHHHHHHHHHHCC
KAEVICMDVAKHDEVLAHTSHLPHLMAFNLVEQLANREDNLDIFRYAAGGFRDFSRIAAS
CCEEEEEEHHHCHHHHHHHHCCHHHHHHHHHHHHHCCCCCCEEEEECCCCHHHHHHHHCC
DPQMWHDIFFANKTAILNAVDGFEKQLTVLRKLIENEDSHALMGLLGHAQAARQHFNHML
CCHHHHHHHHCCCHHEEEHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHH
AKKPLMEKNKVTQQFSILPGNKAFKGKFTVPGDKSVSHRSIMFGAIAEGTTHVTGFLEGE
HHCCCHHHHHHHHEEEECCCCCCCCCEEECCCCCCCCCCEEEEEECCCCCEEEEEEECCC
DALATLQAFRDMGVSIEGPKNGEVTIHGVGMHGLKAPASALYMGNSGTSMRLLSGMLSAQ
HHHHHHHHHHHCCCEEECCCCCCEEEEEECCCCCCCCCCEEEECCCCCHHHHHHHHHHHH
KFDSVMTGDASLSKRPMERIAKPLRLMGAQIQTTGEKGTPPVSITGGQQLKGIQYDLPMA
HHHHHHCCCCHHHHHHHHHHHHHHHHHCCEEEECCCCCCCCEEECCCCCCCCEEECCCCC
SAQVKSGILLAGLWAEGETSVTEPEPTRDHTERMLRAFGYDVKTEGNKISLVGGGKLVGT
HHHHHCCEEEEEEECCCCCCCCCCCCCHHHHHHHHHHHCCCEECCCCEEEEEECCEEEEC
NIQVPSDISSAAFFMVGAAITEGADVVLEAVGINPTRTGVIEILKQMGADLTVENERIAG
CEECCCCCHHHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHCCCEEECCCCCCC
GEPIADIHIKGSRTLKGIHMPEDQVPLAIDEFPALFIAAACAEGQTVLTGAAELRVKESD
CCCEEEEEECCCCEEEECCCCCCCCCEEHHHHHHHHHHHHHCCCCEEEECCEEEEECCCC
RIQVMADGLKIMGIDCTPTEDGIIIEGKGKSGDWSPIFAGGEIESHHDHRIAMSFSMAGL
CEEEEECCEEEEEEECCCCCCCEEEECCCCCCCCCEEEECCCCCCCCCCEEEEEEEECCC
RTSGPITIHGTETVATSFPTFTELANRAGLTIEVSQ
CCCCCEEEECCHHHHCCCCCHHHHHHCCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA