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The map label for this gene is slyD [H]

Identifier: 213158206

GI number: 213158206

Start: 3021597

End: 3022079

Strand: Direct

Name: slyD [H]

Synonym: AB57_2925

Alternate gene names: 213158206

Gene position: 3021597-3022079 (Clockwise)

Preceding gene: 213158205

Following gene: 213158207

Centisome position: 74.6

GC content: 42.65

Gene sequence:

>483_bases
ATGACTGCAATTGCAAATAACCACGTGGTTTCATTCCACTATAAATTAACAAACGCTGAGGGTGAAACACTTGATCAATC
TCAAGGTGAACCACTTGCCTATTTGCATGGCGCAGGCAACATCATTCCTGGTTTAGAAAATGCATTAACTGGTAAGACTG
TTGGTGATAAATTCACTGTTAACGTACCAGCTGCTGAAGGTTATGGCGAATACAACCCAGACCTAGTACAAGAAGTTCCT
GCTCAAATGTTCCAAGGCGTTGATAACATTCAACCAGGTATGCAATTCCAAGCTCAAACAGATGACGGCGTTCAAATCGT
TACTGTTAAAGCGGTTGAAGGTGACAACGTTATCGTTGATGCAAACTTCCCACTTGCTGGTCAAGATTTAACGTTTGAAG
TTGAAATCGTAGAAATCCGTGAAGCTTCTCAAGAAGAATTAGATCACGGTCACGTACACGGTGCGGGTGGTCACCACCAC
TAA

Upstream 100 bases:

>100_bases
AACGCATTAGAAAAAGTGTTAAAGATTGAGATTTTGTAGTCTACAAAATTTATTTTTCACTTTATGATGTACGCTTTAAT
TGATTGAATGGATCAAAAAC

Downstream 100 bases:

>100_bases
GTCTTCTTTTAGAAGATAATAAAAGGCAAAGCTTCGGCTTTGCTTTTTTTATGTCTTTAATTTATATAATATTCATAGAG
TTAATTTATTTTTTAGGGAC

Product: peptidyl-prolyl cis-trans isomerase, FKBP-type

Products: NA

Alternate protein names: PPIase; Metallochaperone slyD [H]

Number of amino acids: Translated: 160; Mature: 159

Protein sequence:

>160_residues
MTAIANNHVVSFHYKLTNAEGETLDQSQGEPLAYLHGAGNIIPGLENALTGKTVGDKFTVNVPAAEGYGEYNPDLVQEVP
AQMFQGVDNIQPGMQFQAQTDDGVQIVTVKAVEGDNVIVDANFPLAGQDLTFEVEIVEIREASQEELDHGHVHGAGGHHH

Sequences:

>Translated_160_residues
MTAIANNHVVSFHYKLTNAEGETLDQSQGEPLAYLHGAGNIIPGLENALTGKTVGDKFTVNVPAAEGYGEYNPDLVQEVP
AQMFQGVDNIQPGMQFQAQTDDGVQIVTVKAVEGDNVIVDANFPLAGQDLTFEVEIVEIREASQEELDHGHVHGAGGHHH
>Mature_159_residues
TAIANNHVVSFHYKLTNAEGETLDQSQGEPLAYLHGAGNIIPGLENALTGKTVGDKFTVNVPAAEGYGEYNPDLVQEVPA
QMFQGVDNIQPGMQFQAQTDDGVQIVTVKAVEGDNVIVDANFPLAGQDLTFEVEIVEIREASQEELDHGHVHGAGGHHH

Specific function: Also involved in hydrogenase metallocenter assembly, probably by participating in the nickel insertion step. This function in hydrogenase biosynthesis requires chaperone activity and the presence of the metal-binding domain, but not PPIase activity [H]

COG id: COG1047

COG function: function code O; FKBP-type peptidyl-prolyl cis-trans isomerases 2

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PPIase FKBP-type domain [H]

Homologues:

Organism=Escherichia coli, GI1789748, Length=145, Percent_Identity=51.7241379310345, Blast_Score=139, Evalue=8e-35,
Organism=Escherichia coli, GI1786211, Length=145, Percent_Identity=32.4137931034483, Blast_Score=70, Evalue=8e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001179 [H]

Pfam domain/function: PF00254 FKBP_C [H]

EC number: =5.2.1.8 [H]

Molecular weight: Translated: 17154; Mature: 17023

Theoretical pI: Translated: 4.18; Mature: 4.18

Prosite motif: PS50059 FKBP_PPIASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTAIANNHVVSFHYKLTNAEGETLDQSQGEPLAYLHGAGNIIPGLENALTGKTVGDKFTV
CCEECCCCEEEEEEEEECCCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCEEEE
NVPAAEGYGEYNPDLVQEVPAQMFQGVDNIQPGMQFQAQTDDGVQIVTVKAVEGDNVIVD
ECCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCEEEECCCCCEEEEEEEEECCCCEEEE
ANFPLAGQDLTFEVEIVEIREASQEELDHGHVHGAGGHHH
CCCCCCCCCEEEEEEEEEECCCCHHHHCCCEEECCCCCCC
>Mature Secondary Structure 
TAIANNHVVSFHYKLTNAEGETLDQSQGEPLAYLHGAGNIIPGLENALTGKTVGDKFTV
CEECCCCEEEEEEEEECCCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCEEEE
NVPAAEGYGEYNPDLVQEVPAQMFQGVDNIQPGMQFQAQTDDGVQIVTVKAVEGDNVIVD
ECCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCEEEECCCCCEEEEEEEEECCCCEEEE
ANFPLAGQDLTFEVEIVEIREASQEELDHGHVHGAGGHHH
CCCCCCCCCEEEEEEEEEECCCCHHHHCCCEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10952301 [H]