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The map label for this gene is phrB [H]

Identifier: 213158207

GI number: 213158207

Start: 3022184

End: 3022765

Strand: Direct

Name: phrB [H]

Synonym: AB57_2926

Alternate gene names: 213158207

Gene position: 3022184-3022765 (Clockwise)

Preceding gene: 213158206

Following gene: 213158208

Centisome position: 74.61

GC content: 35.91

Gene sequence:

>582_bases
ATGTCAAATGCTTATCAGCTCATTTGGTTTCGCCAAGATTTGCGTATACATGATCATGCAGCTTTATGGCACGCCAGCCA
GCAAGGACCTTCACTGGGTTTAGTCATCTTATCGCCAGAGCAATGGAAACAACACGCCGATGCTCCAATAAAAATAAGTT
TTTATTTACGACAACTCAGAACGCTTCAGAAAGAGTTATCAGCACTTCATATTCCACTAGTTATTCAAGTCATTCCCTAT
TGGAAAGAGATCGCAACCTTTATTTCTGATTTCAGCAAGAAATATAATATTGAAAATGTGTATGCCAATATCGAAATAGG
CGTAAATGAATTAAAAAGAGATAAAACGGTACAAGACTATTTAAATCGGCATGGCAAAGAACTATTTTTATTCCATGACC
GTACTATTTTTCCTTTACGTTCAATCCGTAACCAATCACAACAACCATATCAAGTATTTAGTGCATTCAAAAAAGCTTGT
TATACAAAGCTCGACACAAGCGGTTTGTCTCAATGTTATCCGGTCCCTAATAAACAAAATGAAGTACCACTAGATTTTTT
ACAGGGAAAAATATTGATTTAG

Upstream 100 bases:

>100_bases
TCTTTTAGAAGATAATAAAAGGCAAAGCTTCGGCTTTGCTTTTTTTATGTCTTTAATTTATATAATATTCATAGAGTTAA
TTTATTTTTTAGGGACTTGC

Downstream 100 bases:

>100_bases
ACGAAATTGAAAAGCTATTTTGCTCATCTCTCTCAAAAGAACAGCAAGATTTATGGCCTGTTGGCGAACAATACGCATTA
GAACAATTAGATCAATTTAT

Product: deoxyribodipyrimidine photo-lyase

Products: NA

Alternate protein names: DNA photolyase; Photoreactivating enzyme [H]

Number of amino acids: Translated: 193; Mature: 192

Protein sequence:

>193_residues
MSNAYQLIWFRQDLRIHDHAALWHASQQGPSLGLVILSPEQWKQHADAPIKISFYLRQLRTLQKELSALHIPLVIQVIPY
WKEIATFISDFSKKYNIENVYANIEIGVNELKRDKTVQDYLNRHGKELFLFHDRTIFPLRSIRNQSQQPYQVFSAFKKAC
YTKLDTSGLSQCYPVPNKQNEVPLDFLQGKILI

Sequences:

>Translated_193_residues
MSNAYQLIWFRQDLRIHDHAALWHASQQGPSLGLVILSPEQWKQHADAPIKISFYLRQLRTLQKELSALHIPLVIQVIPY
WKEIATFISDFSKKYNIENVYANIEIGVNELKRDKTVQDYLNRHGKELFLFHDRTIFPLRSIRNQSQQPYQVFSAFKKAC
YTKLDTSGLSQCYPVPNKQNEVPLDFLQGKILI
>Mature_192_residues
SNAYQLIWFRQDLRIHDHAALWHASQQGPSLGLVILSPEQWKQHADAPIKISFYLRQLRTLQKELSALHIPLVIQVIPYW
KEIATFISDFSKKYNIENVYANIEIGVNELKRDKTVQDYLNRHGKELFLFHDRTIFPLRSIRNQSQQPYQVFSAFKKACY
TKLDTSGLSQCYPVPNKQNEVPLDFLQGKILI

Specific function: Involved in repair of UV radiation-induced DNA damage. Catalyzes the light-dependent monomerization (300-600 nm) of cyclobutyl pyrimidine dimers (in cis-syn configuration), which are formed between adjacent bases on the same DNA strand upon exposure to ul

COG id: COG0415

COG function: function code L; Deoxyribodipyrimidine photolyase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 DNA photolyase domain [H]

Homologues:

Organism=Escherichia coli, GI1786926, Length=172, Percent_Identity=30.2325581395349, Blast_Score=80, Evalue=8e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002081
- InterPro:   IPR018394
- InterPro:   IPR006050
- InterPro:   IPR005101
- InterPro:   IPR014729 [H]

Pfam domain/function: PF00875 DNA_photolyase; PF03441 FAD_binding_7 [H]

EC number: =4.1.99.3 [H]

Molecular weight: Translated: 22614; Mature: 22483

Theoretical pI: Translated: 9.64; Mature: 9.64

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
0.5 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
1.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNAYQLIWFRQDLRIHDHAALWHASQQGPSLGLVILSPEQWKQHADAPIKISFYLRQLR
CCCCEEEEEEECCCCCCHHHHHHCCCCCCCCEEEEEECHHHHHHHCCCCEEHHHHHHHHH
TLQKELSALHIPLVIQVIPYWKEIATFISDFSKKYNIENVYANIEIGVNELKRDKTVQDY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECHHHHHCCCHHHHH
LNRHGKELFLFHDRTIFPLRSIRNQSQQPYQVFSAFKKACYTKLDTSGLSQCYPVPNKQN
HHCCCCEEEEEECCCCCHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCHHCCCCCCCCC
EVPLDFLQGKILI
CCCHHHHCCEECC
>Mature Secondary Structure 
SNAYQLIWFRQDLRIHDHAALWHASQQGPSLGLVILSPEQWKQHADAPIKISFYLRQLR
CCCEEEEEEECCCCCCHHHHHHCCCCCCCCEEEEEECHHHHHHHCCCCEEHHHHHHHHH
TLQKELSALHIPLVIQVIPYWKEIATFISDFSKKYNIENVYANIEIGVNELKRDKTVQDY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECHHHHHCCCHHHHH
LNRHGKELFLFHDRTIFPLRSIRNQSQQPYQVFSAFKKACYTKLDTSGLSQCYPVPNKQN
HHCCCCEEEEEECCCCCHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCHHCCCCCCCCC
EVPLDFLQGKILI
CCCHHHHCCEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10993077 [H]