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The map label for this gene is ndh [H]

Identifier: 213158205

GI number: 213158205

Start: 3020175

End: 3021461

Strand: Direct

Name: ndh [H]

Synonym: AB57_2924

Alternate gene names: 213158205

Gene position: 3020175-3021461 (Clockwise)

Preceding gene: 213158204

Following gene: 213158206

Centisome position: 74.56

GC content: 39.7

Gene sequence:

>1287_bases
ATGACCCAAAACTTACATCATATTGTTATTGTCGGTGGTGGCGCTGGTGGTTTAGAACTCGCCACGCAACTTGGTGAAAC
TTTTGGGAAAAATGGTAAAGCCAAAATTACATTGGTTGACCAAAATTTAACTCATATCTGGAAACCATTACTTCATGAAA
TTGCGGCGGGTTCTTTAAATCCTCACGAAGAGCAAACCAATTATTTTGCCCATGCAGAGAAACACCACTATGAATTTGTG
TTGGGAACATTAACAGCAGTAAATAAAGATAAGAAAATAATTGATTTAATTCCCCCTCAAGTCTCTAAAGAACAAAATAC
CCATATTCAACAACTCAGTTACGATACACTGGTTTTAGCGCTTGGTTCAGTATCAAATGATTTCAATACACCCGGTGTTC
GTGAAAACTGCCATTTCCTCGATAGCCGTAAACAGGCGGATATTTTCCAGCAAGATCTTTTACACTTATATATCGAAGCG
CAAAATCAACCCGATCAACGTACATTAAATATTGGAATTATTGGTGCGGGGGCAACAGGTGTCGAACTTGCGGCTGAACT
GATTGAAACGACCAAAAACTTTTATCGCTATGGTTTGAAAAAGATCCATCCGAATCAAGTCAAAATTACACTCATTGAGG
CCTCAGAACGCATCCTCCCTGCCCTAAGTGAAAAAACAGCTGAACATAGCGCAAAACAGCTTCAAAAAATGGGTGTTGAA
ATTTTAACTAAACACCGTGTTGAAAAAATTGATGAACACCATATCTATTTTAGTAATGGTAACCAGCTCAACAGTGATAT
TACGGTATGGGCAGCTGGGGTAAAAGCACCAAAAGTACTTGAAAGTCTTAGCGATTTCGAACGTGACAATATTAACCGCT
TAATGGTCTATGCAACGCTGCAGACCTATTCCGATCCTAATGTATTTGCATTTGGTGATTGTGCGCATTGCCAACTTGAT
GCAAGACACCCGCCTCTCGGACCACGCGCTCAAGTTGCTAGTCAACAAGCAAGCTTTTTAGTCGATGCTATGGCTGCTAG
ACTAAATGGTCGATCACAACCGATGTTTACTTTTAACGACAAAGGTTCACTTGTGTCTTTAAGTCGTAATAAAGCGGTTG
GAGAATTACTGGGGGATGTCAGTGTCCAAGGATATATTGCCAAAACGATGTATGTATCTTTATATCGTTTACATCAAGCA
ACAATTCACGGATACACTCAAGCTGGACTACTCACAATGAAAGATTTACTTACAAGACGAGTACGACCAAAAATTAAGCT
GTATTGA

Upstream 100 bases:

>100_bases
AAAACATCAAATTGTGCACAGATGCACAATAAATTTTATAAAGAAAAGATGGCATAATTCAGCCATCTTTTTTTTATAGA
AAAATAATTAGGTGATAAAA

Downstream 100 bases:

>100_bases
GTTGAATTTTTTAAGTTCATCCCTATTTAGATAAAAACGCATTAGAAAAAGTGTTAAAGATTGAGATTTTGTAGTCTACA
AAATTTATTTTTCACTTTAT

Product: NADH dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 428; Mature: 427

Protein sequence:

>428_residues
MTQNLHHIVIVGGGAGGLELATQLGETFGKNGKAKITLVDQNLTHIWKPLLHEIAAGSLNPHEEQTNYFAHAEKHHYEFV
LGTLTAVNKDKKIIDLIPPQVSKEQNTHIQQLSYDTLVLALGSVSNDFNTPGVRENCHFLDSRKQADIFQQDLLHLYIEA
QNQPDQRTLNIGIIGAGATGVELAAELIETTKNFYRYGLKKIHPNQVKITLIEASERILPALSEKTAEHSAKQLQKMGVE
ILTKHRVEKIDEHHIYFSNGNQLNSDITVWAAGVKAPKVLESLSDFERDNINRLMVYATLQTYSDPNVFAFGDCAHCQLD
ARHPPLGPRAQVASQQASFLVDAMAARLNGRSQPMFTFNDKGSLVSLSRNKAVGELLGDVSVQGYIAKTMYVSLYRLHQA
TIHGYTQAGLLTMKDLLTRRVRPKIKLY

Sequences:

>Translated_428_residues
MTQNLHHIVIVGGGAGGLELATQLGETFGKNGKAKITLVDQNLTHIWKPLLHEIAAGSLNPHEEQTNYFAHAEKHHYEFV
LGTLTAVNKDKKIIDLIPPQVSKEQNTHIQQLSYDTLVLALGSVSNDFNTPGVRENCHFLDSRKQADIFQQDLLHLYIEA
QNQPDQRTLNIGIIGAGATGVELAAELIETTKNFYRYGLKKIHPNQVKITLIEASERILPALSEKTAEHSAKQLQKMGVE
ILTKHRVEKIDEHHIYFSNGNQLNSDITVWAAGVKAPKVLESLSDFERDNINRLMVYATLQTYSDPNVFAFGDCAHCQLD
ARHPPLGPRAQVASQQASFLVDAMAARLNGRSQPMFTFNDKGSLVSLSRNKAVGELLGDVSVQGYIAKTMYVSLYRLHQA
TIHGYTQAGLLTMKDLLTRRVRPKIKLY
>Mature_427_residues
TQNLHHIVIVGGGAGGLELATQLGETFGKNGKAKITLVDQNLTHIWKPLLHEIAAGSLNPHEEQTNYFAHAEKHHYEFVL
GTLTAVNKDKKIIDLIPPQVSKEQNTHIQQLSYDTLVLALGSVSNDFNTPGVRENCHFLDSRKQADIFQQDLLHLYIEAQ
NQPDQRTLNIGIIGAGATGVELAAELIETTKNFYRYGLKKIHPNQVKITLIEASERILPALSEKTAEHSAKQLQKMGVEI
LTKHRVEKIDEHHIYFSNGNQLNSDITVWAAGVKAPKVLESLSDFERDNINRLMVYATLQTYSDPNVFAFGDCAHCQLDA
RHPPLGPRAQVASQQASFLVDAMAARLNGRSQPMFTFNDKGSLVSLSRNKAVGELLGDVSVQGYIAKTMYVSLYRLHQAT
IHGYTQAGLLTMKDLLTRRVRPKIKLY

Specific function: Transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. Does not couple the redox reaction to proton translocation [H]

COG id: COG1252

COG function: function code C; NADH dehydrogenase, FAD-containing subunit

Gene ontology:

Cell location: Cell membrane [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NADH dehydrogenase family [H]

Homologues:

Organism=Escherichia coli, GI1787352, Length=438, Percent_Identity=44.5205479452055, Blast_Score=363, Evalue=1e-101,
Organism=Saccharomyces cerevisiae, GI6323794, Length=416, Percent_Identity=26.4423076923077, Blast_Score=92, Evalue=1e-19,
Organism=Saccharomyces cerevisiae, GI6320118, Length=439, Percent_Identity=25.5125284738041, Blast_Score=84, Evalue=5e-17,
Organism=Saccharomyces cerevisiae, GI6323515, Length=448, Percent_Identity=23.4375, Blast_Score=79, Evalue=1e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013027
- InterPro:   IPR001327 [H]

Pfam domain/function: PF00070 Pyr_redox; PF07992 Pyr_redox_2 [H]

EC number: =1.6.99.3 [H]

Molecular weight: Translated: 47671; Mature: 47540

Theoretical pI: Translated: 8.16; Mature: 8.16

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQNLHHIVIVGGGAGGLELATQLGETFGKNGKAKITLVDQNLTHIWKPLLHEIAAGSLN
CCCCCEEEEEEECCCCHHHHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHHHHCCCCC
PHEEQTNYFAHAEKHHYEFVLGTLTAVNKDKKIIDLIPPQVSKEQNTHIQQLSYDTLVLA
CCHHHHHHHHHHHHCCCEEEEEHHHHCCCCCCEEEECCCCCCCCCCCHHHHHHHHHHEEE
LGSVSNDFNTPGVRENCHFLDSRKQADIFQQDLLHLYIEAQNQPDQRTLNIGIIGAGATG
ECCCCCCCCCCCCCCCCHHHCCCHHHHHHHHHHHEEEEECCCCCCCEEEEEEEEECCCHH
VELAAELIETTKNFYRYGLKKIHPNQVKITLIEASERILPALSEKTAEHSAKQLQKMGVE
HHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHH
ILTKHRVEKIDEHHIYFSNGNQLNSDITVWAAGVKAPKVLESLSDFERDNINRLMVYATL
HHHHHHHHHCCCCEEEECCCCCCCCCEEEEEECCCCHHHHHHHHHHCCCCCCEEEEEEEE
QTYSDPNVFAFGDCAHCQLDARHPPLGPRAQVASQQASFLVDAMAARLNGRSQPMFTFND
EECCCCCEEEECCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECC
KGSLVSLSRNKAVGELLGDVSVQGYIAKTMYVSLYRLHQATIHGYTQAGLLTMKDLLTRR
CCCEEEECCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHH
VRPKIKLY
CCCCEECC
>Mature Secondary Structure 
TQNLHHIVIVGGGAGGLELATQLGETFGKNGKAKITLVDQNLTHIWKPLLHEIAAGSLN
CCCCEEEEEEECCCCHHHHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHHHHCCCCC
PHEEQTNYFAHAEKHHYEFVLGTLTAVNKDKKIIDLIPPQVSKEQNTHIQQLSYDTLVLA
CCHHHHHHHHHHHHCCCEEEEEHHHHCCCCCCEEEECCCCCCCCCCCHHHHHHHHHHEEE
LGSVSNDFNTPGVRENCHFLDSRKQADIFQQDLLHLYIEAQNQPDQRTLNIGIIGAGATG
ECCCCCCCCCCCCCCCCHHHCCCHHHHHHHHHHHEEEEECCCCCCCEEEEEEEEECCCHH
VELAAELIETTKNFYRYGLKKIHPNQVKITLIEASERILPALSEKTAEHSAKQLQKMGVE
HHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHH
ILTKHRVEKIDEHHIYFSNGNQLNSDITVWAAGVKAPKVLESLSDFERDNINRLMVYATL
HHHHHHHHHCCCCEEEECCCCCCCCCEEEEEECCCCHHHHHHHHHHCCCCCCEEEEEEEE
QTYSDPNVFAFGDCAHCQLDARHPPLGPRAQVASQQASFLVDAMAARLNGRSQPMFTFND
EECCCCCEEEECCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECC
KGSLVSLSRNKAVGELLGDVSVQGYIAKTMYVSLYRLHQATIHGYTQAGLLTMKDLLTRR
CCCEEEECCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHH
VRPKIKLY
CCCCEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 6265208; 8905232; 9278503 [H]