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The map label for this gene is aroF [H]

Identifier: 213157551

GI number: 213157551

Start: 2326582

End: 2327637

Strand: Reverse

Name: aroF [H]

Synonym: AB57_2242

Alternate gene names: 213157551

Gene position: 2327637-2326582 (Counterclockwise)

Preceding gene: 213157552

Following gene: 213157548

Centisome position: 57.47

GC content: 38.26

Gene sequence:

>1056_bases
ATGAATGCCTTAAATACTTTACTAACTCAAAGCAATACAAAAGAAACACCAGTTAGTTTACCTGTTCAGTTAAAAGCTAA
ATACCCGCTTGTGCAGACCTTCGCACGACAAATTGCAGAACATCGTCAAATTATTCAAAATATTCTTGCTGGCAAAGATC
AGCGCTTAATGGTTATTACAGGACCATGTTCAATTCATGACCCAATTGCTGTACTTGAATACGCAGATAGATTGCAAAAA
TTACAAGAAAAAGTAAAAGATCAAATCTTCATTGTGATGCGTGCTTATATTGAAAAGCCGCGTACAACAGTAGGTTGGAA
AGGGTTTATGTATGACCCAAACCTTGATGGTTCATCTAATCTACAATTAGGTTTAGAAAAATCGCGTGAGCTATATTTAC
AAATTATTGAAAAAGGCTTGCCGATTGCGAGCGAAATTTTAAGCCCAATGGCAACAGGCTATTTTGATGATTTATTGGCT
TGGGGTGCAATTGGAGCTCGTACTAGTGAGTCCCAGATTCACCGTGAAATCTCAAGTCATATGCCATACAGTATTGGCTT
CAAGAATGGTACGGATGGCTCAATTCAAATTGCTTTAGATGCTATTCAGTCTGCACAAAATGAGCATCAATTTTTAGGTA
TGAATCAGCAAGGTTTGCCTTCAGTGATTCAGAGTTCTGGAAATCCATTGCCACACCTGATTTTGCGTGGAGCCAATCAC
GGTCCTAATTATGATTTGGCTTCAATTCAGGCAATTAGAGAAAAGCACAAACAAAATCTACCTGCCTTAGTTATTGACTG
TAGTCATGGCAACAGTGGTAAAGATCCTTTACGTCAGCCAGAAGTTTTACAGCAAATCGTTGCTGAACGTCTAAAAACTC
AGGTAAAGGGTGTCATGATTGAAAGCCATTTAGTTGATGGTAACCAGAAGATTTCATGTGAAATGACTTATGGACAGTCG
GTAACGGACGGTTGTTTAGGGTGGGATAAAACTGAACAGCTTTTGTTAAATGTTGCTAAACAATTAAAAGCAAGTGAATT
AGCTCATTCGGCTTAA

Upstream 100 bases:

>100_bases
TTTATTGGTTTTACTTTTGCCTACCTTTGCCAACGAATAGATCCAAAACGCTCAAATAAATGATCGGACTGATTAGGTTT
CAGTCCAAAGGAAAAGACCA

Downstream 100 bases:

>100_bases
TGATGTAAACATTTAAAAAGGGATCTGTTTTAGCAGATCCTTTTTTTTAAGAAGCATGTTTAAGTTCGGATAAAAAAGTA
GTAATTTCATGCCCGAATTT

Product: phospho-2-dehydro-3-deoxyheptonate aldolase

Products: NA

Alternate protein names: 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase; DAHP synthase; Phospho-2-keto-3-deoxyheptonate aldolase [H]

Number of amino acids: Translated: 351; Mature: 351

Protein sequence:

>351_residues
MNALNTLLTQSNTKETPVSLPVQLKAKYPLVQTFARQIAEHRQIIQNILAGKDQRLMVITGPCSIHDPIAVLEYADRLQK
LQEKVKDQIFIVMRAYIEKPRTTVGWKGFMYDPNLDGSSNLQLGLEKSRELYLQIIEKGLPIASEILSPMATGYFDDLLA
WGAIGARTSESQIHREISSHMPYSIGFKNGTDGSIQIALDAIQSAQNEHQFLGMNQQGLPSVIQSSGNPLPHLILRGANH
GPNYDLASIQAIREKHKQNLPALVIDCSHGNSGKDPLRQPEVLQQIVAERLKTQVKGVMIESHLVDGNQKISCEMTYGQS
VTDGCLGWDKTEQLLLNVAKQLKASELAHSA

Sequences:

>Translated_351_residues
MNALNTLLTQSNTKETPVSLPVQLKAKYPLVQTFARQIAEHRQIIQNILAGKDQRLMVITGPCSIHDPIAVLEYADRLQK
LQEKVKDQIFIVMRAYIEKPRTTVGWKGFMYDPNLDGSSNLQLGLEKSRELYLQIIEKGLPIASEILSPMATGYFDDLLA
WGAIGARTSESQIHREISSHMPYSIGFKNGTDGSIQIALDAIQSAQNEHQFLGMNQQGLPSVIQSSGNPLPHLILRGANH
GPNYDLASIQAIREKHKQNLPALVIDCSHGNSGKDPLRQPEVLQQIVAERLKTQVKGVMIESHLVDGNQKISCEMTYGQS
VTDGCLGWDKTEQLLLNVAKQLKASELAHSA
>Mature_351_residues
MNALNTLLTQSNTKETPVSLPVQLKAKYPLVQTFARQIAEHRQIIQNILAGKDQRLMVITGPCSIHDPIAVLEYADRLQK
LQEKVKDQIFIVMRAYIEKPRTTVGWKGFMYDPNLDGSSNLQLGLEKSRELYLQIIEKGLPIASEILSPMATGYFDDLLA
WGAIGARTSESQIHREISSHMPYSIGFKNGTDGSIQIALDAIQSAQNEHQFLGMNQQGLPSVIQSSGNPLPHLILRGANH
GPNYDLASIQAIREKHKQNLPALVIDCSHGNSGKDPLRQPEVLQQIVAERLKTQVKGVMIESHLVDGNQKISCEMTYGQS
VTDGCLGWDKTEQLLLNVAKQLKASELAHSA

Specific function: Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) [H]

COG id: COG0722

COG function: function code E; 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I DAHP synthase family [H]

Homologues:

Organism=Escherichia coli, GI1788953, Length=346, Percent_Identity=46.5317919075145, Blast_Score=322, Evalue=2e-89,
Organism=Escherichia coli, GI1786969, Length=332, Percent_Identity=46.6867469879518, Blast_Score=305, Evalue=4e-84,
Organism=Escherichia coli, GI1787996, Length=326, Percent_Identity=48.7730061349693, Blast_Score=303, Evalue=1e-83,
Organism=Saccharomyces cerevisiae, GI6320240, Length=340, Percent_Identity=43.2352941176471, Blast_Score=296, Evalue=4e-81,
Organism=Saccharomyces cerevisiae, GI6319726, Length=334, Percent_Identity=42.5149700598802, Blast_Score=295, Evalue=6e-81,

Paralogues:

None

Copy number: 2,200 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR006218
- InterPro:   IPR006219 [H]

Pfam domain/function: PF00793 DAHP_synth_1 [H]

EC number: =2.5.1.54 [H]

Molecular weight: Translated: 38845; Mature: 38845

Theoretical pI: Translated: 7.36; Mature: 7.36

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNALNTLLTQSNTKETPVSLPVQLKAKYPLVQTFARQIAEHRQIIQNILAGKDQRLMVIT
CCHHHHHHHCCCCCCCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEE
GPCSIHDPIAVLEYADRLQKLQEKVKDQIFIVMRAYIEKPRTTVGWKGFMYDPNLDGSSN
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEECCCCCCCCC
LQLGLEKSRELYLQIIEKGLPIASEILSPMATGYFDDLLAWGAIGARTSESQIHREISSH
CEECHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHC
MPYSIGFKNGTDGSIQIALDAIQSAQNEHQFLGMNQQGLPSVIQSSGNPLPHLILRGANH
CCEEEECCCCCCCEEEEHHHHHHHCCCHHHHCCCCCCCCHHHHHCCCCCCCHHEEECCCC
GPNYDLASIQAIREKHKQNLPALVIDCSHGNSGKDPLRQPEVLQQIVAERLKTQVKGVMI
CCCCCHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
ESHLVDGNQKISCEMTYGQSVTDGCLGWDKTEQLLLNVAKQLKASELAHSA
HHEEECCCCEEEEEEECCCCCCHHHCCCCHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MNALNTLLTQSNTKETPVSLPVQLKAKYPLVQTFARQIAEHRQIIQNILAGKDQRLMVIT
CCHHHHHHHCCCCCCCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEE
GPCSIHDPIAVLEYADRLQKLQEKVKDQIFIVMRAYIEKPRTTVGWKGFMYDPNLDGSSN
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEECCCCCCCCC
LQLGLEKSRELYLQIIEKGLPIASEILSPMATGYFDDLLAWGAIGARTSESQIHREISSH
CEECHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHC
MPYSIGFKNGTDGSIQIALDAIQSAQNEHQFLGMNQQGLPSVIQSSGNPLPHLILRGANH
CCEEEECCCCCCCEEEEHHHHHHHCCCHHHHCCCCCCCCHHHHHCCCCCCCHHEEECCCC
GPNYDLASIQAIREKHKQNLPALVIDCSHGNSGKDPLRQPEVLQQIVAERLKTQVKGVMI
CCCCCHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
ESHLVDGNQKISCEMTYGQSVTDGCLGWDKTEQLLLNVAKQLKASELAHSA
HHEEECCCCEEEEEEECCCCCCHHHCCCCHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 6146618; 6396419; 9205837; 9278503; 1977738; 6104668; 2857723; 9056491 [H]