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The map label for this gene is fadH [H]

Identifier: 213157548

GI number: 213157548

Start: 2322895

End: 2324919

Strand: Reverse

Name: fadH [H]

Synonym: AB57_2239

Alternate gene names: 213157548

Gene position: 2324919-2322895 (Counterclockwise)

Preceding gene: 213157551

Following gene: 213157547

Centisome position: 57.4

GC content: 40.64

Gene sequence:

>2025_bases
ATGTCGTTATATCCACATTTATTAAAACCATTAGATTTAGGTTTTACGACATTAAAAAATCGCGTATTGATGGGGTCTAT
GCATGTTGGTCTAGAAGAAGCGCCTGGTGGTTATGAGCGTATGGCAGCTTTTTATGCAGAACGTGCTAAAGGTGATGTTG
GGCTCATTGTTACTGGCGGTATTGCACCTAATCAGGCAGGTTTAACCTTTGCTCATGCTTCTAAGTTAGATAGCACAGAA
GAAGCCGAAAAGCATAAAGTCATTACCGAAGCTGTACATGCTGCTGGCGGGAAGATTGCATTACAAATATTACATACGGG
CCGATATTCTTATCAGCCAGAGATTGTTGCGCCTTCGGCAATTCAGGCACCTATTAATCCCATTAAGCCTAAGGCAATGA
CTTCTGCTGAGGTTCAACAAACGATTGATGATTTTGCAAACTGTGCGAAGCTTGCTCAATACGCTGGATATGACGGCGTT
GAGATTATGGGTTCAGAAGGTTATTTAATTAATGAGTTTATTGCAGCCAGAACAAACCATCGTGATGATGAATGGGGTGG
TAGCTATGAAAACCGTATTCGTTTTCCTGTTGAGATTGTAAAACGTACACGTGAAATAGTGGGTGAAAACTTTATTATTA
TTTACCGATTATCGATGCTTGATCTGGTTGAAGGTGGTTCTACTTTAGAAGAAGTTATTCAACTTGCGAAAGCGATTGAA
AAAGCTGGGGCTACGATCATTAATACGGGTATTGGCTGGCATGAAGCTCGTATACCAACAATTGCGACCAAAGTTCCAAG
AGCTGCATTTACTTGGGTCACTGAAAAATTAAAAGGTGAAGTTTCAGTTCCATTAATTACATCAAACCGTATTAATACAC
CAGAAATGGCTGAACATGTATTAGCGTCGGGTCATGCGGATATGGTTTCAATGGCACGTCCAATGCTTGCAGATCCTGAG
TTTGTTTTAAAAGCAAGTGAAGGCCGTAGTGATGAAATTAATACGTGTATTGGCTGTAACCAAGCTTGTCTCGACCACAT
TTTCTCTATGAAAATTGCAACATGTTTGGTTAATCCTCGAGCATGTTATGAAACAGAACTAATCTTTAAAGAAGCACAAA
ATCAGAAAAATATTGCTGTCATTGGGGCCGGGCCAGCAGGTTTAAGTTTTGCTGTATATGCGGCAGATCGTGGACACCAA
GTTAAAATCTTTGAAGCAAGTCATCAAATTGGTGGTCAGTTTAATATCGCTAAAACTGTGCCAGGTAAAGAAGAGTTCTA
CGAAACATTACGTTATTTCAATCGTCAAATTGAATTACGCCCAAACATTGAACTTGTATTAAACCATCCAGCCACTTATG
AAGAGTTAAGTCAATCAGACTTTGATGAAATCGTAGTAGCAACTGGTGTAACACCTCGTCAATTACAATTTGAAGGTATT
GATCATCCAAAAGTGTTGAGCTACTTACAGGTGCTTAAAGAGCGTGTACCAGTAGGTCAGCGTGTTGCCATTATTGGTGC
GGGTGGTATTGGTTTTGATACGGCTGAGTACCTAACCCATGAAGGTGAAAGTGGCAGTTTAAATCCAGAAAAATTTTATG
AAGAGTGGGGTATTGATACTCACTATGAACATGTTGGTGGTTTAAAGCAGCCAAAAGTTGAAGCTTCTGAACGAGAAATC
TATTTGTTGCAGCGTAAAGCTTCCTCAGTAGGCGCGGGGCTGGGTAAAACGACTGGTTGGATTCACCGTACCGGGCTTAA
GAACAGAAACGTGAAAATGTTAGCAGGTGTGCAATACGACAAAGTAGATGATCAAGGGCTTCATATTACTGTTGATGGCA
AACCAACAGTGCTTGAGGTTGATAATGTTGTGATTTGCGCGGGCCAAGAATCATTTACTGCGATGTATGACCAATTAAAA
GCAGATGGTAAAAATGTTCATTTGATTGGTGGTGCTAAAGAAGCAGGTGAGTTGGATGCTAAACGTGCTATTCGTCAAGG
TGCTGAACTAGCAGCGGTACTTTAA

Upstream 100 bases:

>100_bases
CATTAGATTATGCAACATGTTGCATAAAAGTCAAAATTTGATTATAAATTTGTGCAACAAGTTGCATTAAGCAAGCAGAT
TAGCAAGCCAAGGAGTTGTT

Downstream 100 bases:

>100_bases
TGGCTTAAATGAGCATTGTCTTGGGTAAGAGAATGCTCATTACTAAAACCTATTTGAAGGAAAAATAAAAAATGACACTC
GAAATAACTAAACAGTCATT

Product: FAD/FMN-binding/pyridine nucleotide-disulphide oxidoreductase family protein

Products: NA

Alternate protein names: 2,4-dienoyl coenzyme A reductase [H]

Number of amino acids: Translated: 674; Mature: 673

Protein sequence:

>674_residues
MSLYPHLLKPLDLGFTTLKNRVLMGSMHVGLEEAPGGYERMAAFYAERAKGDVGLIVTGGIAPNQAGLTFAHASKLDSTE
EAEKHKVITEAVHAAGGKIALQILHTGRYSYQPEIVAPSAIQAPINPIKPKAMTSAEVQQTIDDFANCAKLAQYAGYDGV
EIMGSEGYLINEFIAARTNHRDDEWGGSYENRIRFPVEIVKRTREIVGENFIIIYRLSMLDLVEGGSTLEEVIQLAKAIE
KAGATIINTGIGWHEARIPTIATKVPRAAFTWVTEKLKGEVSVPLITSNRINTPEMAEHVLASGHADMVSMARPMLADPE
FVLKASEGRSDEINTCIGCNQACLDHIFSMKIATCLVNPRACYETELIFKEAQNQKNIAVIGAGPAGLSFAVYAADRGHQ
VKIFEASHQIGGQFNIAKTVPGKEEFYETLRYFNRQIELRPNIELVLNHPATYEELSQSDFDEIVVATGVTPRQLQFEGI
DHPKVLSYLQVLKERVPVGQRVAIIGAGGIGFDTAEYLTHEGESGSLNPEKFYEEWGIDTHYEHVGGLKQPKVEASEREI
YLLQRKASSVGAGLGKTTGWIHRTGLKNRNVKMLAGVQYDKVDDQGLHITVDGKPTVLEVDNVVICAGQESFTAMYDQLK
ADGKNVHLIGGAKEAGELDAKRAIRQGAELAAVL

Sequences:

>Translated_674_residues
MSLYPHLLKPLDLGFTTLKNRVLMGSMHVGLEEAPGGYERMAAFYAERAKGDVGLIVTGGIAPNQAGLTFAHASKLDSTE
EAEKHKVITEAVHAAGGKIALQILHTGRYSYQPEIVAPSAIQAPINPIKPKAMTSAEVQQTIDDFANCAKLAQYAGYDGV
EIMGSEGYLINEFIAARTNHRDDEWGGSYENRIRFPVEIVKRTREIVGENFIIIYRLSMLDLVEGGSTLEEVIQLAKAIE
KAGATIINTGIGWHEARIPTIATKVPRAAFTWVTEKLKGEVSVPLITSNRINTPEMAEHVLASGHADMVSMARPMLADPE
FVLKASEGRSDEINTCIGCNQACLDHIFSMKIATCLVNPRACYETELIFKEAQNQKNIAVIGAGPAGLSFAVYAADRGHQ
VKIFEASHQIGGQFNIAKTVPGKEEFYETLRYFNRQIELRPNIELVLNHPATYEELSQSDFDEIVVATGVTPRQLQFEGI
DHPKVLSYLQVLKERVPVGQRVAIIGAGGIGFDTAEYLTHEGESGSLNPEKFYEEWGIDTHYEHVGGLKQPKVEASEREI
YLLQRKASSVGAGLGKTTGWIHRTGLKNRNVKMLAGVQYDKVDDQGLHITVDGKPTVLEVDNVVICAGQESFTAMYDQLK
ADGKNVHLIGGAKEAGELDAKRAIRQGAELAAVL
>Mature_673_residues
SLYPHLLKPLDLGFTTLKNRVLMGSMHVGLEEAPGGYERMAAFYAERAKGDVGLIVTGGIAPNQAGLTFAHASKLDSTEE
AEKHKVITEAVHAAGGKIALQILHTGRYSYQPEIVAPSAIQAPINPIKPKAMTSAEVQQTIDDFANCAKLAQYAGYDGVE
IMGSEGYLINEFIAARTNHRDDEWGGSYENRIRFPVEIVKRTREIVGENFIIIYRLSMLDLVEGGSTLEEVIQLAKAIEK
AGATIINTGIGWHEARIPTIATKVPRAAFTWVTEKLKGEVSVPLITSNRINTPEMAEHVLASGHADMVSMARPMLADPEF
VLKASEGRSDEINTCIGCNQACLDHIFSMKIATCLVNPRACYETELIFKEAQNQKNIAVIGAGPAGLSFAVYAADRGHQV
KIFEASHQIGGQFNIAKTVPGKEEFYETLRYFNRQIELRPNIELVLNHPATYEELSQSDFDEIVVATGVTPRQLQFEGID
HPKVLSYLQVLKERVPVGQRVAIIGAGGIGFDTAEYLTHEGESGSLNPEKFYEEWGIDTHYEHVGGLKQPKVEASEREIY
LLQRKASSVGAGLGKTTGWIHRTGLKNRNVKMLAGVQYDKVDDQGLHITVDGKPTVLEVDNVVICAGQESFTAMYDQLKA
DGKNVHLIGGAKEAGELDAKRAIRQGAELAAVL

Specific function: Catalyzes the NADP-dependent reduction of 2,4-dienoyl- CoA to yield trans-2- enoyl-CoA [H]

COG id: COG1902

COG function: function code C; NADH:flavin oxidoreductases, Old Yellow Enzyme family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1789463, Length=670, Percent_Identity=63.2835820895522, Blast_Score=875, Evalue=0.0,
Organism=Escherichia coli, GI1787939, Length=351, Percent_Identity=29.9145299145299, Blast_Score=115, Evalue=1e-26,
Organism=Caenorhabditis elegans, GI17566914, Length=309, Percent_Identity=27.831715210356, Blast_Score=94, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI17540738, Length=310, Percent_Identity=25.1612903225806, Blast_Score=93, Evalue=4e-19,
Organism=Caenorhabditis elegans, GI17559804, Length=307, Percent_Identity=24.7557003257329, Blast_Score=87, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI17564188, Length=306, Percent_Identity=25.1633986928105, Blast_Score=87, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI17559802, Length=310, Percent_Identity=24.5161290322581, Blast_Score=86, Evalue=5e-17,
Organism=Caenorhabditis elegans, GI72001454, Length=307, Percent_Identity=26.7100977198697, Blast_Score=86, Evalue=6e-17,
Organism=Caenorhabditis elegans, GI17565138, Length=303, Percent_Identity=25.4125412541254, Blast_Score=81, Evalue=2e-15,
Organism=Saccharomyces cerevisiae, GI6325086, Length=225, Percent_Identity=29.7777777777778, Blast_Score=91, Evalue=6e-19,
Organism=Saccharomyces cerevisiae, GI6321973, Length=255, Percent_Identity=28.2352941176471, Blast_Score=87, Evalue=8e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR013027
- InterPro:   IPR001155 [H]

Pfam domain/function: PF00724 Oxidored_FMN; PF07992 Pyr_redox_2 [H]

EC number: =1.3.1.34 [H]

Molecular weight: Translated: 73704; Mature: 73573

Theoretical pI: Translated: 5.90; Mature: 5.90

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLYPHLLKPLDLGFTTLKNRVLMGSMHVGLEEAPGGYERMAAFYAERAKGDVGLIVTGG
CCCCHHHHHHHHCCHHHHHCEEEEEHEECCCCCCCCHHHHHHHHHHHHCCCCEEEEEECC
IAPNQAGLTFAHASKLDSTEEAEKHKVITEAVHAAGGKIALQILHTGRYSYQPEIVAPSA
CCCCCCCEEEEHHHCCCCHHHHHHHHHHHHHHHHCCCEEEEEEEECCCCCCCCCEECCCH
IQAPINPIKPKAMTSAEVQQTIDDFANCAKLAQYAGYDGVEIMGSEGYLINEFIAARTNH
HHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCHHHHHHHHCCC
RDDEWGGSYENRIRFPVEIVKRTREIVGENFIIIYRLSMLDLVEGGSTLEEVIQLAKAIE
CCCCCCCCCCCCEECHHHHHHHHHHHHCCCEEEEEEEHHHHHHCCCHHHHHHHHHHHHHH
KAGATIINTGIGWHEARIPTIATKVPRAAFTWVTEKLKGEVSVPLITSNRINTPEMAEHV
HCCCEEEECCCCCCCCCCCHHHHHCCHHHHHHHHHHHCCCEEEEEEECCCCCCHHHHHHH
LASGHADMVSMARPMLADPEFVLKASEGRSDEINTCIGCNQACLDHIFSMKIATCLVNPR
HHCCCHHHHHHHCCCCCCCHHEEEECCCCCCCCCHHHCCCHHHHHHHHHHHHHHHHCCCH
ACYETELIFKEAQNQKNIAVIGAGPAGLSFAVYAADRGHQVKIFEASHQIGGQFNIAKTV
HHHHHHHHHHHHCCCCCEEEEECCCCCCEEEEEEECCCCEEEEEECCCCCCCEEEEEECC
PGKEEFYETLRYFNRQIELRPNIELVLNHPATYEELSQSDFDEIVVATGVTPRQLQFEGI
CCHHHHHHHHHHHCCEEEECCCEEEEECCCCCHHHHHCCCCCCEEEECCCCCCEEEECCC
DHPKVLSYLQVLKERVPVGQRVAIIGAGGIGFDTAEYLTHEGESGSLNPEKFYEEWGIDT
CCHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCHHHHHHCCCCCCCCCHHHHHHHCCCCC
HYEHVGGLKQPKVEASEREIYLLQRKASSVGAGLGKTTGWIHRTGLKNRNVKMLAGVQYD
CHHHHCCCCCCCCCCCCCEEEEEEEHHHHHCCCCCCCCCEEEECCCCCCCEEEEECCEEC
KVDDQGLHITVDGKPTVLEVDNVVICAGQESFTAMYDQLKADGKNVHLIGGAKEAGELDA
CCCCCCEEEEECCCCCEEEECCEEEEECCHHHHHHHHHHHCCCCEEEEEECCCCCCHHHH
KRAIRQGAELAAVL
HHHHHCCCHHHHCC
>Mature Secondary Structure 
SLYPHLLKPLDLGFTTLKNRVLMGSMHVGLEEAPGGYERMAAFYAERAKGDVGLIVTGG
CCCHHHHHHHHCCHHHHHCEEEEEHEECCCCCCCCHHHHHHHHHHHHCCCCEEEEEECC
IAPNQAGLTFAHASKLDSTEEAEKHKVITEAVHAAGGKIALQILHTGRYSYQPEIVAPSA
CCCCCCCEEEEHHHCCCCHHHHHHHHHHHHHHHHCCCEEEEEEEECCCCCCCCCEECCCH
IQAPINPIKPKAMTSAEVQQTIDDFANCAKLAQYAGYDGVEIMGSEGYLINEFIAARTNH
HHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCHHHHHHHHCCC
RDDEWGGSYENRIRFPVEIVKRTREIVGENFIIIYRLSMLDLVEGGSTLEEVIQLAKAIE
CCCCCCCCCCCCEECHHHHHHHHHHHHCCCEEEEEEEHHHHHHCCCHHHHHHHHHHHHHH
KAGATIINTGIGWHEARIPTIATKVPRAAFTWVTEKLKGEVSVPLITSNRINTPEMAEHV
HCCCEEEECCCCCCCCCCCHHHHHCCHHHHHHHHHHHCCCEEEEEEECCCCCCHHHHHHH
LASGHADMVSMARPMLADPEFVLKASEGRSDEINTCIGCNQACLDHIFSMKIATCLVNPR
HHCCCHHHHHHHCCCCCCCHHEEEECCCCCCCCCHHHCCCHHHHHHHHHHHHHHHHCCCH
ACYETELIFKEAQNQKNIAVIGAGPAGLSFAVYAADRGHQVKIFEASHQIGGQFNIAKTV
HHHHHHHHHHHHCCCCCEEEEECCCCCCEEEEEEECCCCEEEEEECCCCCCCEEEEEECC
PGKEEFYETLRYFNRQIELRPNIELVLNHPATYEELSQSDFDEIVVATGVTPRQLQFEGI
CCHHHHHHHHHHHCCEEEECCCEEEEECCCCCHHHHHCCCCCCEEEECCCCCCEEEECCC
DHPKVLSYLQVLKERVPVGQRVAIIGAGGIGFDTAEYLTHEGESGSLNPEKFYEEWGIDT
CCHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCHHHHHHCCCCCCCCCHHHHHHHCCCCC
HYEHVGGLKQPKVEASEREIYLLQRKASSVGAGLGKTTGWIHRTGLKNRNVKMLAGVQYD
CHHHHCCCCCCCCCCCCCEEEEEEEHHHHHCCCCCCCCCEEEECCCCCCCEEEEECCEEC
KVDDQGLHITVDGKPTVLEVDNVVICAGQESFTAMYDQLKADGKNVHLIGGAKEAGELDA
CCCCCCEEEEECCCCCEEEECCEEEEECCHHHHHHHHHHHCCCCEEEEEECCCCCCHHHH
KRAIRQGAELAAVL
HHHHHCCCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9346310; 9278503 [H]