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The map label for this gene is mutS2 [H]

Identifier: 212223860

GI number: 212223860

Start: 664576

End: 666306

Strand: Reverse

Name: mutS2 [H]

Synonym: TON_0711

Alternate gene names: 212223860

Gene position: 666306-664576 (Counterclockwise)

Preceding gene: 212223862

Following gene: 212223859

Centisome position: 36.06

GC content: 54.19

Gene sequence:

>1731_bases
ATGACCCTCAAGCTTAACCCAGAGGCTAAGGCAATCTACCGGGCGATACTCGAGGAGATAAAGAGGCGGTTAGTCCTTCC
TGGAAGCTCGGCTTTTCTTGACGAGTTTGGGCCGGTTTCTGAGAGGGATGAAATCCTCCGCAGACAGGCATATTTCAAAG
AGAACCTGCCGAAAATCCGGCCCGAACTCAGGAAATATCTCTCGAAGGTTCGGCCCATAAAGTTCAGGCGCGACTTCCTC
CACGACAGGGTTTTAATAGTTGATGAGGGCGAGCTTGAAAAAGCAGAGAATTTAAACCTCTGTGCGGTCTCGACCAGCCT
TGAGGATGCCGAAGGCTATCCCCTCGTCCTCAGCACCGTTGGCTACGGCATCGATGTTGAGCTTACACCTTCCGATATAG
CTCCTGAGCTCTACATCATGCCTCTATGGGAGAACAAAGAGACGCTTCAAGCCCTCGTGAGTATAGGTGAGCTCACAGGA
GAGAAGAGCGTTGCGAAAGAAATTCTCGAGGCGCTTAAAGAACTCGAAGAAGTCATGGAAAAAAGGAGGCTCCTTGATGG
GCTCGAAGAACTGATAGCCGGCAAGGAGCGCGAGCTGAACGAGAAGATTTCAGAAAAGCTCGAGAAGTTCAGCCTGACGC
TGAGCGGGAAAGAACTGCTTGAATTCCTGAGCGAGCTTAAAGCCGGGAACTACGAGGCGATTTTCTCGCACTTCGGTGAG
GTTGAGGGTGGAATCTTGGACCTCATCAACGAGGCCGAGGAAGAGCTGAGCGAAAAGCTCGGCGTCACGGTTGAGCTGTT
CTCCCGCGAGGATCTCTATCCCGTCACAGTTCCCCCAGAGAGAGTCGAAATGCTGAGAGAGGAACTTGAGAAGGAACTCA
AGGTGGAGCTCTACCTCAAGAGCCGCGAGGTTCTCGGAAAAATCCGTCCGCTTCTGGCCAGGCTTAAGGAAGAGCTGGCT
GGGGTTTACGAGCTGGACTTCCTGAGGGCAGTGAAGGAGTTCGCGGAGGGCTTCACCTTCCCCGAGCTCTGGAACGGTGG
AATCGCGTTCATCAACGGAAGGCATCTCTTCATCGAAAATCCCCAGCCGGTGAGCTACGTCGTTGGGAGAAAGCCCGAGA
ACTTTGATCTCCCCGGCGTGGAGAAGGTAAAGGACGAGCCCGTAGTAATCCTCACCGGTGCGAACAGCGGTGGAAAAACT
TCACTCCTAGAGCTGATCACACAGATAACGCTTCTCGCCCACATGGGGCTGCCAGTTCCGGCGGAGAAAGCGTGGGTGGA
ACCCCTCAACGAGCTTTTCTTCTTCAGGCGTAAGAGGAGCGTCTACGGTGCCGGAGCCTTTGAGACGGCCTTGAGGTCTT
TCGTGAGAGCACTGAAGGGAGAGGGCAGAAAGCTGATCCTCATAGACGAGTTCGAGGCCATAACCGAACCGGGGGCGGCT
GTCAAGATAATCGGAGAGCTCCTCAAAGTCGCCTATGAGAGGGGCTTTTACGTTGTCATAGTTTCACACCTCGGCGAGGA
TCTGAGGAGGGAGCTGCCCTTCGCGAGGGTCGATGGGATAGAGGCCAAAGGTCTAGACGAGAACCTCGACCTCATTGTGG
ACAGGCAGCCGAAGTTTGGAACGCTCGGAAGAAGCACGCCCGAGCTCATAGTCGAGCGCCTCGCAAAGAAGAAGCGTGGA
AGAGAGAGGGAGATTTTTGAGAGAGTTTGGAGGGCGTTCAGGGGCTTTTAA

Upstream 100 bases:

>100_bases
CATCCTTATAAAATTTCCCGGGATTTCCCTTGATGGATTGCGCTGGTGTGAGACGGTGAATGTCGGAAGGTTTTTTAGAC
TTCGGCCCATTTCTTGAACG

Downstream 100 bases:

>100_bases
TATGTAGGTCGTTGTGTAGGTAGTTACTACATCGTCTTATGGTTAGGTTATTACTTTTGTTAATTAGAAATATTTAAGTA
TTTTTATTCCCCTAGCTCTT

Product: MutS-like DNA mismatch repair ATPase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 576; Mature: 575

Protein sequence:

>576_residues
MTLKLNPEAKAIYRAILEEIKRRLVLPGSSAFLDEFGPVSERDEILRRQAYFKENLPKIRPELRKYLSKVRPIKFRRDFL
HDRVLIVDEGELEKAENLNLCAVSTSLEDAEGYPLVLSTVGYGIDVELTPSDIAPELYIMPLWENKETLQALVSIGELTG
EKSVAKEILEALKELEEVMEKRRLLDGLEELIAGKERELNEKISEKLEKFSLTLSGKELLEFLSELKAGNYEAIFSHFGE
VEGGILDLINEAEEELSEKLGVTVELFSREDLYPVTVPPERVEMLREELEKELKVELYLKSREVLGKIRPLLARLKEELA
GVYELDFLRAVKEFAEGFTFPELWNGGIAFINGRHLFIENPQPVSYVVGRKPENFDLPGVEKVKDEPVVILTGANSGGKT
SLLELITQITLLAHMGLPVPAEKAWVEPLNELFFFRRKRSVYGAGAFETALRSFVRALKGEGRKLILIDEFEAITEPGAA
VKIIGELLKVAYERGFYVVIVSHLGEDLRRELPFARVDGIEAKGLDENLDLIVDRQPKFGTLGRSTPELIVERLAKKKRG
REREIFERVWRAFRGF

Sequences:

>Translated_576_residues
MTLKLNPEAKAIYRAILEEIKRRLVLPGSSAFLDEFGPVSERDEILRRQAYFKENLPKIRPELRKYLSKVRPIKFRRDFL
HDRVLIVDEGELEKAENLNLCAVSTSLEDAEGYPLVLSTVGYGIDVELTPSDIAPELYIMPLWENKETLQALVSIGELTG
EKSVAKEILEALKELEEVMEKRRLLDGLEELIAGKERELNEKISEKLEKFSLTLSGKELLEFLSELKAGNYEAIFSHFGE
VEGGILDLINEAEEELSEKLGVTVELFSREDLYPVTVPPERVEMLREELEKELKVELYLKSREVLGKIRPLLARLKEELA
GVYELDFLRAVKEFAEGFTFPELWNGGIAFINGRHLFIENPQPVSYVVGRKPENFDLPGVEKVKDEPVVILTGANSGGKT
SLLELITQITLLAHMGLPVPAEKAWVEPLNELFFFRRKRSVYGAGAFETALRSFVRALKGEGRKLILIDEFEAITEPGAA
VKIIGELLKVAYERGFYVVIVSHLGEDLRRELPFARVDGIEAKGLDENLDLIVDRQPKFGTLGRSTPELIVERLAKKKRG
REREIFERVWRAFRGF
>Mature_575_residues
TLKLNPEAKAIYRAILEEIKRRLVLPGSSAFLDEFGPVSERDEILRRQAYFKENLPKIRPELRKYLSKVRPIKFRRDFLH
DRVLIVDEGELEKAENLNLCAVSTSLEDAEGYPLVLSTVGYGIDVELTPSDIAPELYIMPLWENKETLQALVSIGELTGE
KSVAKEILEALKELEEVMEKRRLLDGLEELIAGKERELNEKISEKLEKFSLTLSGKELLEFLSELKAGNYEAIFSHFGEV
EGGILDLINEAEEELSEKLGVTVELFSREDLYPVTVPPERVEMLREELEKELKVELYLKSREVLGKIRPLLARLKEELAG
VYELDFLRAVKEFAEGFTFPELWNGGIAFINGRHLFIENPQPVSYVVGRKPENFDLPGVEKVKDEPVVILTGANSGGKTS
LLELITQITLLAHMGLPVPAEKAWVEPLNELFFFRRKRSVYGAGAFETALRSFVRALKGEGRKLILIDEFEAITEPGAAV
KIIGELLKVAYERGFYVVIVSHLGEDLRRELPFARVDGIEAKGLDENLDLIVDRQPKFGTLGRSTPELIVERLAKKKRGR
EREIFERVWRAFRGF

Specific function: This Protein Is Involved In The Repair Of Mismatches In DNA. It Is Possible That It Carries Out The Mismatch Recognition Step. This Protein Has A Weak Atpase Activity. [C]

COG id: COG1193

COG function: function code L; Mismatch repair ATPase (MutS family)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 Smr domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005747
- InterPro:   IPR000432
- InterPro:   IPR007696
- InterPro:   IPR002625 [H]

Pfam domain/function: PF00488 MutS_V; PF01713 Smr [H]

EC number: NA

Molecular weight: Translated: 65522; Mature: 65390

Theoretical pI: Translated: 4.87; Mature: 4.87

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.0 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
0.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLKLNPEAKAIYRAILEEIKRRLVLPGSSAFLDEFGPVSERDEILRRQAYFKENLPKIR
CEEEECCHHHHHHHHHHHHHHHHEECCCCHHHHHHCCCCCHHHHHHHHHHHHHHCCHHCC
PELRKYLSKVRPIKFRRDFLHDRVLIVDEGELEKAENLNLCAVSTSLEDAEGYPLVLSTV
HHHHHHHHHCCCHHHHHHHHHCEEEEEECCCCCCCCCCCEEEEECCCCCCCCCCEEEEEC
GYGIDVELTPSDIAPELYIMPLWENKETLQALVSIGELTGEKSVAKEILEALKELEEVME
CCCEEEEECCCCCCCCEEEEEECCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHH
KRRLLDGLEELIAGKERELNEKISEKLEKFSLTLSGKELLEFLSELKAGNYEAIFSHFGE
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCHHHHHHHHHC
VEGGILDLINEAEEELSEKLGVTVELFSREDLYPVTVPPERVEMLREELEKELKVELYLK
CCCHHHHHHHHHHHHHHHHHCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHEEH
SREVLGKIRPLLARLKEELAGVYELDFLRAVKEFAEGFTFPELWNGGIAFINGRHLFIEN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCCEEEEECEEEEEEC
PQPVSYVVGRKPENFDLPGVEKVKDEPVVILTGANSGGKTSLLELITQITLLAHMGLPVP
CCCCEEEECCCCCCCCCCCCHHCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCCC
AEKAWVEPLNELFFFRRKRSVYGAGAFETALRSFVRALKGEGRKLILIDEFEAITEPGAA
CHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCEEEEEECHHHHCCCCHH
VKIIGELLKVAYERGFYVVIVSHLGEDLRRELPFARVDGIEAKGLDENLDLIVDRQPKFG
HHHHHHHHHHHHHCCEEEEEHHHCCHHHHHHCCCHHHCCCCCCCCCCCCCEEEECCCCCC
TLGRSTPELIVERLAKKKRGREREIFERVWRAFRGF
CCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TLKLNPEAKAIYRAILEEIKRRLVLPGSSAFLDEFGPVSERDEILRRQAYFKENLPKIR
EEEECCHHHHHHHHHHHHHHHHEECCCCHHHHHHCCCCCHHHHHHHHHHHHHHCCHHCC
PELRKYLSKVRPIKFRRDFLHDRVLIVDEGELEKAENLNLCAVSTSLEDAEGYPLVLSTV
HHHHHHHHHCCCHHHHHHHHHCEEEEEECCCCCCCCCCCEEEEECCCCCCCCCCEEEEEC
GYGIDVELTPSDIAPELYIMPLWENKETLQALVSIGELTGEKSVAKEILEALKELEEVME
CCCEEEEECCCCCCCCEEEEEECCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHH
KRRLLDGLEELIAGKERELNEKISEKLEKFSLTLSGKELLEFLSELKAGNYEAIFSHFGE
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCHHHHHHHHHC
VEGGILDLINEAEEELSEKLGVTVELFSREDLYPVTVPPERVEMLREELEKELKVELYLK
CCCHHHHHHHHHHHHHHHHHCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHEEH
SREVLGKIRPLLARLKEELAGVYELDFLRAVKEFAEGFTFPELWNGGIAFINGRHLFIEN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCCEEEEECEEEEEEC
PQPVSYVVGRKPENFDLPGVEKVKDEPVVILTGANSGGKTSLLELITQITLLAHMGLPVP
CCCCEEEECCCCCCCCCCCCHHCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCCC
AEKAWVEPLNELFFFRRKRSVYGAGAFETALRSFVRALKGEGRKLILIDEFEAITEPGAA
CHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCEEEEEECHHHHCCCCHH
VKIIGELLKVAYERGFYVVIVSHLGEDLRRELPFARVDGIEAKGLDENLDLIVDRQPKFG
HHHHHHHHHHHHHCCEEEEEHHHCCHHHHHHCCCHHHCCCCCCCCCCCCCEEEECCCCCC
TLGRSTPELIVERLAKKKRGREREIFERVWRAFRGF
CCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA