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The map label for this gene is mcpB [H]

Identifier: 212223859

GI number: 212223859

Start: 663203

End: 664462

Strand: Reverse

Name: mcpB [H]

Synonym: TON_0710

Alternate gene names: 212223859

Gene position: 664462-663203 (Counterclockwise)

Preceding gene: 212223860

Following gene: 212223856

Centisome position: 35.96

GC content: 53.1

Gene sequence:

>1260_bases
ATGGAACAGCGAAGTGTGATAATCATATCCCCAGTACTTGTGTTCCTGCTCACCATAGTGCCCTCGATATTCGTGGGCAC
TATAGGCGCGGTCGTAGGCGGTGCAATTGGGGTGCTGACAGCGATCATGCTGGTCCGGAGTTCTACAGTAGAGCATGGTA
TTCCTCTAGATGTTCTTAAGTACAAGCAGGAGATAGAGGAGCAGATCCGCGTTATTGCTCAGATACTTGACAGAATAGCC
GAGGGTGACCTTTCGGTCGAAGATAAAAACCTAAGCGGCCACCTTTCTGAGATACGGGAAGCCATAGAAAAGATGAGGCA
GGGTCTTGCGGCAATGATCCAAAACATACAAAATGCTGCTGTTATTGTTCAGGATCGCAGTAAGCTCATCAGTGAGAACG
TGGAGCAGATAAGCGAGGCAATTAACCAGGTTGCCGAGGCCATCAACCAGGTCAGCATAGAGGCCCAGCGCGAGCAAGAG
AATATCAACCACATGACAGAGACGATGCGCTACATCGATGAGATTGGCAAGGAGACCATCAGCACCATGGAGGACTTCGA
GCGTTCCATGAGGGAGGTTGTTTCGCTCGCAAGGGAGGGTGGCCAGAAGGGTCAGGAGGCCGTTGGCCAGATAGAGGAGA
TCAGAAACATGATGCTCATGATAGAGGAGACTGTAAAGGGAGTCGCGGAGATGGGCAAGAACATCGCCAGCATCACCAAC
GTCATCACCGGCATAGCCGAGCAGACCAACCTCCTCGCCCTCAACGCGGCAATAGAGGCTGCTAGGGCGGGGGAAGCTGG
TAAAGGCTTCGCCGTCGTTGCAGAGGAGATCAGAAACCTCGCAGAGGAGAGCAAGAACGCAGCGGACGACATCCGCAACA
TCGTCACCCAGATTATGGAGAAGATACAAGAGAGCGTCGATGTCACTGGCAAGAGCGTGGAGACCGTTACTCAATCAACA
GAAGTCCTCAAGGAGAGCGTCTCCTATCTCACACACATAGCAGAACTCATTGAGGAGATGGAGATCAAGGCAAACGAGCT
TAAGAGCAAGGTTCTCGAGGAGGGTGAGAAGATAGACGAGGGTCTACGCTTCCTCGAGAACCTTGCGGCCAGCGCTGAGG
AGACGACCGCCGCTGCCGAGCAGGTTAGTGCCGCCGCTGAGGAGCAGACATCGGCGCTCGAGGAGGTCCGTGCCACGCTT
AGGGACTTTGAGAGGGTTGTCGAAAACCTCATGCAGGCGGTTAATAGATTTAAGATTTGA

Upstream 100 bases:

>100_bases
GTGTAGGTAGTTACTACATCGTCTTATGGTTAGGTTATTACTTTTGTTAATTAGAAATATTTAAGTATTTTTATTCCCCT
AGCTCTTCGGAGGGATCGAC

Downstream 100 bases:

>100_bases
AGCCCAATATTATCCTTGGCCTTTCTTTATATCCTCTCCAGCAGAAGATTATTATATTCAGCCAACCCAGCTCCTCTCCC
TGTACCGTCCCCTGCTCTCG

Product: methyl-accepting chemotaxis protein

Products: NA

Alternate protein names: H3 [H]

Number of amino acids: Translated: 419; Mature: 419

Protein sequence:

>419_residues
MEQRSVIIISPVLVFLLTIVPSIFVGTIGAVVGGAIGVLTAIMLVRSSTVEHGIPLDVLKYKQEIEEQIRVIAQILDRIA
EGDLSVEDKNLSGHLSEIREAIEKMRQGLAAMIQNIQNAAVIVQDRSKLISENVEQISEAINQVAEAINQVSIEAQREQE
NINHMTETMRYIDEIGKETISTMEDFERSMREVVSLAREGGQKGQEAVGQIEEIRNMMLMIEETVKGVAEMGKNIASITN
VITGIAEQTNLLALNAAIEAARAGEAGKGFAVVAEEIRNLAEESKNAADDIRNIVTQIMEKIQESVDVTGKSVETVTQST
EVLKESVSYLTHIAELIEEMEIKANELKSKVLEEGEKIDEGLRFLENLAASAEETTAAAEQVSAAAEEQTSALEEVRATL
RDFERVVENLMQAVNRFKI

Sequences:

>Translated_419_residues
MEQRSVIIISPVLVFLLTIVPSIFVGTIGAVVGGAIGVLTAIMLVRSSTVEHGIPLDVLKYKQEIEEQIRVIAQILDRIA
EGDLSVEDKNLSGHLSEIREAIEKMRQGLAAMIQNIQNAAVIVQDRSKLISENVEQISEAINQVAEAINQVSIEAQREQE
NINHMTETMRYIDEIGKETISTMEDFERSMREVVSLAREGGQKGQEAVGQIEEIRNMMLMIEETVKGVAEMGKNIASITN
VITGIAEQTNLLALNAAIEAARAGEAGKGFAVVAEEIRNLAEESKNAADDIRNIVTQIMEKIQESVDVTGKSVETVTQST
EVLKESVSYLTHIAELIEEMEIKANELKSKVLEEGEKIDEGLRFLENLAASAEETTAAAEQVSAAAEEQTSALEEVRATL
RDFERVVENLMQAVNRFKI
>Mature_419_residues
MEQRSVIIISPVLVFLLTIVPSIFVGTIGAVVGGAIGVLTAIMLVRSSTVEHGIPLDVLKYKQEIEEQIRVIAQILDRIA
EGDLSVEDKNLSGHLSEIREAIEKMRQGLAAMIQNIQNAAVIVQDRSKLISENVEQISEAINQVAEAINQVSIEAQREQE
NINHMTETMRYIDEIGKETISTMEDFERSMREVVSLAREGGQKGQEAVGQIEEIRNMMLMIEETVKGVAEMGKNIASITN
VITGIAEQTNLLALNAAIEAARAGEAGKGFAVVAEEIRNLAEESKNAADDIRNIVTQIMEKIQESVDVTGKSVETVTQST
EVLKESVSYLTHIAELIEEMEIKANELKSKVLEEGEKIDEGLRFLENLAASAEETTAAAEQVSAAAEEQTSALEEVRATL
RDFERVVENLMQAVNRFKI

Specific function: Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside to the inside of the cell, and facilitate sensory adaptation through the variation of the level of

COG id: COG0840

COG function: function code NT; Methyl-accepting chemotaxis protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI1787690, Length=334, Percent_Identity=29.0419161676647, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI1789453, Length=206, Percent_Identity=30.0970873786408, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI1788195, Length=155, Percent_Identity=38.0645161290323, Blast_Score=92, Evalue=5e-20,
Organism=Escherichia coli, GI2367378, Length=169, Percent_Identity=36.094674556213, Blast_Score=89, Evalue=4e-19,
Organism=Escherichia coli, GI1788194, Length=214, Percent_Identity=30.3738317757009, Blast_Score=86, Evalue=4e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004010
- InterPro:   IPR003122
- InterPro:   IPR004089
- InterPro:   IPR003660
- InterPro:   IPR022094 [H]

Pfam domain/function: PF02743 Cache_1; PF00672 HAMP; PF12332 McpA_N; PF00015 MCPsignal; PF02203 TarH [H]

EC number: NA

Molecular weight: Translated: 46013; Mature: 46013

Theoretical pI: Translated: 4.25; Mature: 4.25

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEQRSVIIISPVLVFLLTIVPSIFVGTIGAVVGGAIGVLTAIMLVRSSTVEHGIPLDVLK
CCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHH
YKQEIEEQIRVIAQILDRIAEGDLSVEDKNLSGHLSEIREAIEKMRQGLAAMIQNIQNAA
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
VIVQDRSKLISENVEQISEAINQVAEAINQVSIEAQREQENINHMTETMRYIDEIGKETI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
STMEDFERSMREVVSLAREGGQKGQEAVGQIEEIRNMMLMIEETVKGVAEMGKNIASITN
HHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VITGIAEQTNLLALNAAIEAARAGEAGKGFAVVAEEIRNLAEESKNAADDIRNIVTQIME
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHH
KIQESVDVTGKSVETVTQSTEVLKESVSYLTHIAELIEEMEIKANELKSKVLEEGEKIDE
HHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GLRFLENLAASAEETTAAAEQVSAAAEEQTSALEEVRATLRDFERVVENLMQAVNRFKI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MEQRSVIIISPVLVFLLTIVPSIFVGTIGAVVGGAIGVLTAIMLVRSSTVEHGIPLDVLK
CCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHH
YKQEIEEQIRVIAQILDRIAEGDLSVEDKNLSGHLSEIREAIEKMRQGLAAMIQNIQNAA
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
VIVQDRSKLISENVEQISEAINQVAEAINQVSIEAQREQENINHMTETMRYIDEIGKETI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
STMEDFERSMREVVSLAREGGQKGQEAVGQIEEIRNMMLMIEETVKGVAEMGKNIASITN
HHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VITGIAEQTNLLALNAAIEAARAGEAGKGFAVVAEEIRNLAEESKNAADDIRNIVTQIME
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHH
KIQESVDVTGKSVETVTQSTEVLKESVSYLTHIAELIEEMEIKANELKSKVLEEGEKIDE
HHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GLRFLENLAASAEETTAAAEQVSAAAEEQTSALEEVRATLRDFERVVENLMQAVNRFKI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8188684; 9384377 [H]