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The map label for this gene is moaC

Identifier: 212223862

GI number: 212223862

Start: 666969

End: 667439

Strand: Reverse

Name: moaC

Synonym: TON_0713

Alternate gene names: 212223862

Gene position: 667439-666969 (Counterclockwise)

Preceding gene: 212223863

Following gene: 212223860

Centisome position: 36.12

GC content: 56.69

Gene sequence:

>471_bases
ATGAAGGAACTAACCCACGTCGATGAAAAAGGTGTCAAGATGGTCGAGGTTGGGCATAAGAGGGAGGTCCTCAGAAAGGC
TGTCGCGAAGGGCAGGATACGGCTCAGACCGGAGACTATCGAGCTGATAAAGGCCGGGAAGACGAAGAAGGGCAACGTTA
TTGCGACGGCGCAGATTGCTGGAATTCTGGCCGTCAAAAAGACGCCCGAGCTGATTCCGCTCTGCCACCCGATACCGCTC
ACGGGCGTGGACATCTCCTTCGAGTTCGGCGAGGACTACATCGAGGCCACCTGCGAGGTTCGCGCGACCTACAAGACCGG
AGTCGAGATGGAGGCCCTGATGGGGGTAACCCTCGCGCTGCTGACCATATGGGACATGGTTAAGGCCGTCGAGAAAGACG
AGCAGGGTCAGTATCCGTTCACGAGAATTGAGGGCATCCACGTAGTCGAAAAGGTGAAGGAAGAAGGCTGA

Upstream 100 bases:

>100_bases
GTCGTCCACGAGGCTGGCATTGCCAAGCTCGTCGCCAGGATGCGCCCGATGGGTGTTGCGAAGGGCTGATGCCTTTCTTT
CAACTTTTGGGGGCGTTGCA

Downstream 100 bases:

>100_bases
GGCCTTTCTTTTCTCATTCCCTGCAGTATCCCAGGATAAAATATTCGAGGGTTTTAAGCAGGTCATTGAGGAAGAAGCCC
AGGAGCACGAGGAAGAAGCC

Product: putative molybdenum cofactor biosynthesis protein MoaC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 156; Mature: 156

Protein sequence:

>156_residues
MKELTHVDEKGVKMVEVGHKREVLRKAVAKGRIRLRPETIELIKAGKTKKGNVIATAQIAGILAVKKTPELIPLCHPIPL
TGVDISFEFGEDYIEATCEVRATYKTGVEMEALMGVTLALLTIWDMVKAVEKDEQGQYPFTRIEGIHVVEKVKEEG

Sequences:

>Translated_156_residues
MKELTHVDEKGVKMVEVGHKREVLRKAVAKGRIRLRPETIELIKAGKTKKGNVIATAQIAGILAVKKTPELIPLCHPIPL
TGVDISFEFGEDYIEATCEVRATYKTGVEMEALMGVTLALLTIWDMVKAVEKDEQGQYPFTRIEGIHVVEKVKEEG
>Mature_156_residues
MKELTHVDEKGVKMVEVGHKREVLRKAVAKGRIRLRPETIELIKAGKTKKGNVIATAQIAGILAVKKTPELIPLCHPIPL
TGVDISFEFGEDYIEATCEVRATYKTGVEMEALMGVTLALLTIWDMVKAVEKDEQGQYPFTRIEGIHVVEKVKEEG

Specific function: Together with moaA, is involved in the conversion of a guanosine derivative (5'-GTP) into molybdopterin precursor Z

COG id: COG0315

COG function: function code H; Molybdenum cofactor biosynthesis enzyme

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the moaC family

Homologues:

Organism=Escherichia coli, GI1787001, Length=138, Percent_Identity=47.1014492753623, Blast_Score=117, Evalue=3e-28,
Organism=Caenorhabditis elegans, GI32566331, Length=132, Percent_Identity=45.4545454545455, Blast_Score=101, Evalue=1e-22,
Organism=Drosophila melanogaster, GI28574490, Length=134, Percent_Identity=43.2835820895522, Blast_Score=102, Evalue=9e-23,
Organism=Drosophila melanogaster, GI28574492, Length=122, Percent_Identity=42.6229508196721, Blast_Score=96, Evalue=7e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MOAC_THEON (B6YVC3)

Other databases:

- EMBL:   CP000855
- RefSeq:   YP_002307098.1
- GeneID:   7017014
- GenomeReviews:   CP000855_GR
- KEGG:   ton:TON_0713
- HOGENOM:   HBG605231
- OMA:   PMCHPLM
- ProtClustDB:   PRK12343
- HAMAP:   MF_01224_A
- InterPro:   IPR023045
- InterPro:   IPR023047
- InterPro:   IPR002820
- Gene3D:   G3DSA:3.30.70.640
- TIGRFAMs:   TIGR00581

Pfam domain/function: PF01967 MoaC; SSF55040 MoaC

EC number: NA

Molecular weight: Translated: 17338; Mature: 17338

Theoretical pI: Translated: 7.58; Mature: 7.58

Prosite motif: NA

Important sites: ACT_SITE 125-125

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKELTHVDEKGVKMVEVGHKREVLRKAVAKGRIRLRPETIELIKAGKTKKGNVIATAQIA
CCCCCCCCCCCCEEEECCCHHHHHHHHHHCCEEEECHHHHHHHHCCCCCCCCEEEEHHHH
GILAVKKTPELIPLCHPIPLTGVDISFEFGEDYIEATCEVRATYKTGVEMEALMGVTLAL
EEEEECCCCCCCCCCCCCCCCCEEEEEECCHHHHHHHHHEEEEHHCCCHHHHHHHHHHHH
LTIWDMVKAVEKDEQGQYPFTRIEGIHVVEKVKEEG
HHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKELTHVDEKGVKMVEVGHKREVLRKAVAKGRIRLRPETIELIKAGKTKKGNVIATAQIA
CCCCCCCCCCCCEEEECCCHHHHHHHHHHCCEEEECHHHHHHHHCCCCCCCCEEEEHHHH
GILAVKKTPELIPLCHPIPLTGVDISFEFGEDYIEATCEVRATYKTGVEMEALMGVTLAL
EEEEECCCCCCCCCCCCCCCCCEEEEEECCHHHHHHHHHEEEEHHCCCHHHHHHHHHHHH
LTIWDMVKAVEKDEQGQYPFTRIEGIHVVEKVKEEG
HHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Involved in molybdopterin biosynthesis [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA