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The map label for this gene is glmS [H]

Identifier: 209551373

GI number: 209551373

Start: 3933297

End: 3934328

Strand: Reverse

Name: glmS [H]

Synonym: Rleg2_3802

Alternate gene names: 209551373

Gene position: 3934328-3933297 (Counterclockwise)

Preceding gene: 209551374

Following gene: 209551372

Centisome position: 86.7

GC content: 65.6

Gene sequence:

>1032_bases
ATGAGTGAGAACCAGTCGCTGATGCTTCAAGAAGCGGGCCAATCGCCGGAGGTGGTGGCCACGCTTCTCGAAAAGGAAAA
ACCGGTCTTTGCCGAGATTGCCCGGCTGTTTTCGTCCGCCCGCCCGAGCGTGGTGACGACGGCGGCGCGCGGTTCCTCGG
ACCACGCCGCCACCTTCTTCAAATATCTTTTCGAGATCACCTGCGGCGTCCCGGTCGCATCGGTCGGGCCGTCGATCGCT
TCGGTCTATGGCGCTGCCCTTCATCTGAAGGGCGGCGTTCATTTCACCGTCTCGCAGTCGGGCGCCAGCCCCGATATCGT
CGCATTGCAGGAGGCGGCCAAGAAGGGCGGGGCGACGACGATCGCCGTCGTCAACGTCACCGACAGCCCGCTGGCGAAAC
AGGCCGATATCGTTCTCGGCCTCAATGCCGGCGCAGAAAAGAGCGTCGCGGCGACAAAATCCTTCATCGCCTCGGTCGCC
GCGCTTTCCGGGGTGACGGCTGCGATCGGCGGCGCGTCCGAGCTGCAGGCAGCACTCGGCAAGCTGCCGGAGGCGCTTTC
AGCCACCGCGGGGATCGACACGGCGGCAGCCGAAGAGGTGCTCTTCAACGCGACCTCGCTCTATACGGCCGGCCGCGGCC
CGGCCTTCGCGATCGCGCTCGAAGCGGCGCTGAAGGCCAAGGAAACGTCCGGCCTGCATGCCGAAGCCTTCTCGCTGGCG
GAACTGATGCACGGTCCGATGCGGCTGGTGCAGCCGGGCTTTCCGATCGTCGCCTTTGCGCCCGACGATGCGGCCTTCAC
CAATAACGGCCAGGCGCTGGAACGTCTGCAGAAGCTCGGCGCCACCACTGTCGGTTTCTCCACGCAGCCGCTTTCCGGCG
TCAATCTGCGCGTGCCGACGACGGGCAACGGCCTGGTCGATCCGCTGGTGTCGCTGCTCGTCTATTACCGGCTGATCGAG
TCGGTGACGCGGCGCAAGGGCTTCGATCCCGACAGGCCGGCAAACCTGCTCAAGGTGACGGAGACGGTCTGA

Upstream 100 bases:

>100_bases
TCTCGCGTCTGGAAGACCAGCGCGTCGTTGAATACACCCGCTCGCATTATCGCGGCGATGCCTATGATTTCGTTGCCGAA
TTGAGAATCGGAGATGACCT

Downstream 100 bases:

>100_bases
TGGCCCGTAAGATCTTCATCGGCGCGCGCATCTTCGATGGCGAGCGCTTCCATGACGACAAGGCGCTCATCGTTGCCGAT
GGACGGGTCGAAGCGATTGC

Product: glutamine--fructose-6-phosphate transaminase

Products: NA

Alternate protein names: D-fructose-6-phosphate amidotransferase; GFAT; Glucosamine-6-phosphate synthase; Hexosephosphate aminotransferase; L-glutamine-D-fructose-6-phosphate amidotransferase [H]

Number of amino acids: Translated: 343; Mature: 342

Protein sequence:

>343_residues
MSENQSLMLQEAGQSPEVVATLLEKEKPVFAEIARLFSSARPSVVTTAARGSSDHAATFFKYLFEITCGVPVASVGPSIA
SVYGAALHLKGGVHFTVSQSGASPDIVALQEAAKKGGATTIAVVNVTDSPLAKQADIVLGLNAGAEKSVAATKSFIASVA
ALSGVTAAIGGASELQAALGKLPEALSATAGIDTAAAEEVLFNATSLYTAGRGPAFAIALEAALKAKETSGLHAEAFSLA
ELMHGPMRLVQPGFPIVAFAPDDAAFTNNGQALERLQKLGATTVGFSTQPLSGVNLRVPTTGNGLVDPLVSLLVYYRLIE
SVTRRKGFDPDRPANLLKVTETV

Sequences:

>Translated_343_residues
MSENQSLMLQEAGQSPEVVATLLEKEKPVFAEIARLFSSARPSVVTTAARGSSDHAATFFKYLFEITCGVPVASVGPSIA
SVYGAALHLKGGVHFTVSQSGASPDIVALQEAAKKGGATTIAVVNVTDSPLAKQADIVLGLNAGAEKSVAATKSFIASVA
ALSGVTAAIGGASELQAALGKLPEALSATAGIDTAAAEEVLFNATSLYTAGRGPAFAIALEAALKAKETSGLHAEAFSLA
ELMHGPMRLVQPGFPIVAFAPDDAAFTNNGQALERLQKLGATTVGFSTQPLSGVNLRVPTTGNGLVDPLVSLLVYYRLIE
SVTRRKGFDPDRPANLLKVTETV
>Mature_342_residues
SENQSLMLQEAGQSPEVVATLLEKEKPVFAEIARLFSSARPSVVTTAARGSSDHAATFFKYLFEITCGVPVASVGPSIAS
VYGAALHLKGGVHFTVSQSGASPDIVALQEAAKKGGATTIAVVNVTDSPLAKQADIVLGLNAGAEKSVAATKSFIASVAA
LSGVTAAIGGASELQAALGKLPEALSATAGIDTAAAEEVLFNATSLYTAGRGPAFAIALEAALKAKETSGLHAEAFSLAE
LMHGPMRLVQPGFPIVAFAPDDAAFTNNGQALERLQKLGATTVGFSTQPLSGVNLRVPTTGNGLVDPLVSLLVYYRLIES
VTRRKGFDPDRPANLLKVTETV

Specific function: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source [H]

COG id: COG2222

COG function: function code M; Predicted phosphosugar isomerases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 SIS domains [H]

Homologues:

Organism=Homo sapiens, GI205277386, Length=273, Percent_Identity=27.8388278388278, Blast_Score=94, Evalue=1e-19,
Organism=Homo sapiens, GI4826742, Length=273, Percent_Identity=27.4725274725275, Blast_Score=93, Evalue=3e-19,
Organism=Escherichia coli, GI1790167, Length=319, Percent_Identity=30.4075235109718, Blast_Score=112, Evalue=5e-26,
Organism=Caenorhabditis elegans, GI17539970, Length=271, Percent_Identity=28.7822878228782, Blast_Score=100, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI17532899, Length=271, Percent_Identity=28.7822878228782, Blast_Score=100, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI17532897, Length=271, Percent_Identity=28.7822878228782, Blast_Score=100, Evalue=2e-21,
Organism=Saccharomyces cerevisiae, GI6322745, Length=324, Percent_Identity=28.0864197530864, Blast_Score=91, Evalue=3e-19,
Organism=Saccharomyces cerevisiae, GI6323731, Length=235, Percent_Identity=28.0851063829787, Blast_Score=75, Evalue=2e-14,
Organism=Drosophila melanogaster, GI21357745, Length=365, Percent_Identity=26.5753424657534, Blast_Score=96, Evalue=3e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000583
- InterPro:   IPR017932
- InterPro:   IPR005855
- InterPro:   IPR001347 [H]

Pfam domain/function: PF00310 GATase_2; PF01380 SIS [H]

EC number: =2.6.1.16 [H]

Molecular weight: Translated: 35203; Mature: 35072

Theoretical pI: Translated: 6.04; Mature: 6.04

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSENQSLMLQEAGQSPEVVATLLEKEKPVFAEIARLFSSARPSVVTTAARGSSDHAATFF
CCCCCCCHHHHCCCCHHHHHHHHHCCCCHHHHHHHHHHCCCCCEEEEECCCCCCHHHHHH
KYLFEITCGVPVASVGPSIASVYGAALHLKGGVHFTVSQSGASPDIVALQEAAKKGGATT
HHHHHHHCCCCHHHCCHHHHHHHHHHEEECCCEEEEEECCCCCCCHHHHHHHHHCCCCEE
IAVVNVTDSPLAKQADIVLGLNAGAEKSVAATKSFIASVAALSGVTAAIGGASELQAALG
EEEEEECCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHH
KLPEALSATAGIDTAAAEEVLFNATSLYTAGRGPAFAIALEAALKAKETSGLHAEAFSLA
HCHHHHHHHCCCCHHHHHHHHHHHHHHEECCCCCEEHHHHHHHHHHHHCCCCHHHHHHHH
ELMHGPMRLVQPGFPIVAFAPDDAAFTNNGQALERLQKLGATTVGFSTQPLSGVNLRVPT
HHHHCCHHHHCCCCCEEEECCCCCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCEEECCC
TGNGLVDPLVSLLVYYRLIESVTRRKGFDPDRPANLLKVTETV
CCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHEEEECCC
>Mature Secondary Structure 
SENQSLMLQEAGQSPEVVATLLEKEKPVFAEIARLFSSARPSVVTTAARGSSDHAATFF
CCCCCCHHHHCCCCHHHHHHHHHCCCCHHHHHHHHHHCCCCCEEEEECCCCCCHHHHHH
KYLFEITCGVPVASVGPSIASVYGAALHLKGGVHFTVSQSGASPDIVALQEAAKKGGATT
HHHHHHHCCCCHHHCCHHHHHHHHHHEEECCCEEEEEECCCCCCCHHHHHHHHHCCCCEE
IAVVNVTDSPLAKQADIVLGLNAGAEKSVAATKSFIASVAALSGVTAAIGGASELQAALG
EEEEEECCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHH
KLPEALSATAGIDTAAAEEVLFNATSLYTAGRGPAFAIALEAALKAKETSGLHAEAFSLA
HCHHHHHHHCCCCHHHHHHHHHHHHHHEECCCCCEEHHHHHHHHHHHHCCCCHHHHHHHH
ELMHGPMRLVQPGFPIVAFAPDDAAFTNNGQALERLQKLGATTVGFSTQPLSGVNLRVPT
HHHHCCHHHHCCCCCEEEECCCCCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCEEECCC
TGNGLVDPLVSLLVYYRLIESVTRRKGFDPDRPANLLKVTETV
CCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11930014 [H]