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The map label for this gene is nagA [H]

Identifier: 209551372

GI number: 209551372

Start: 3932146

End: 3933297

Strand: Reverse

Name: nagA [H]

Synonym: Rleg2_3801

Alternate gene names: 209551372

Gene position: 3933297-3932146 (Counterclockwise)

Preceding gene: 209551373

Following gene: 209551371

Centisome position: 86.68

GC content: 66.58

Gene sequence:

>1152_bases
ATGGCCCGTAAGATCTTCATCGGCGCGCGCATCTTCGATGGCGAGCGCTTCCATGACGACAAGGCGCTCATCGTTGCCGA
TGGACGGGTCGAAGCGATTGCGGCTGGAAACGATCTGCCGGATGGCGAGACGGTGACGCTTGCCGGCGGCGTGCTGTCGG
CCGGCTTCATCGATGCGCAGGTCAATGGCGGCGCCGGGCGGATGCTGAACGACGAACCTTCCGCCGCCTCGATGGCGATC
ATCGCCGGCGGGCACCGGCCCTATGGCACGACATCGCTGCTGCCGACGCTGATCACCGATACATCGGAGGCATCCATTGC
CGCGATCGAGGCGGCGACAGAAGCGGTCAAGGCGAACCGCGGCGTCGCCGGCCTGCATCTCGAAGGCCCACATCTGGCGC
CGGCCCGCAAGGGCGCGCATCTGGCCGAACTGATGCGGCCGGTCGAGGACCGCGACCTCAAGGCCTTCATCCGGGCACGC
GAGGCGATCGGCACGCTGCTCGTCACCATGGCGGCCGAGCAGGTAACGGTTGCCCAGGTGCGCGAACTTGCCGAAGGCGG
CGTCACCGTCAGCATCGGCCATTCCGATTGCTCGAGCGAGGCGGCGGAGGAACGTTTCGATGCCGGGGCGCGAGGTGTCA
CGCATCTTTTCAACGCCATGAGCCAGATGGGGCACCGTGCGCCAGGTCTCGTCGGCGCGGCGATCGACCATCCCTCGACC
TGGTGCGGCATCATCGCCGACGGTCACCATGTCGATCCGAAAGCCCTGCGCACGGCGCTGCGCGCCAAGCGCGGCGAAGG
CAAGCTGTTCTTCGTCACCGATGCAATGTCGCTCGTCGGGTCTGAGAAGGATTCCTTTACGCTGAACGGGCGCACCGTCC
GGCGCGAAAGAGGCGGCTTCTGCTCGAAGCTGGTGCTGTCCGACGGCACGCTGGCCGGTTCCGACGTCGACATGATCTCG
ACGATCCGCTACGGCGTCACCTATCTCGACCTGACGCTCGCCGAAGCCCTGCGCATGGCAACGCTCTACCCCGCCCGTTT
CCTCAGGCTTGCCGATCGCGGCCATCTCTCGCCGGGCGCGCGCGCCGATCTTGTGCATCTCACCGATGCGCTAACTGTCA
CCGCCACCTGGCTTGCCGGCGAAACGGCGTGA

Upstream 100 bases:

>100_bases
CGCTGCTCGTCTATTACCGGCTGATCGAGTCGGTGACGCGGCGCAAGGGCTTCGATCCCGACAGGCCGGCAAACCTGCTC
AAGGTGACGGAGACGGTCTG

Downstream 100 bases:

>100_bases
CCTCAAGGAGACGTGGGATGACCGATATCACCGATGCCTACTTCTCCAACCTGATCGTCCGGCTGGAAGAATTGAAGCAG
ACGCTTGCCGAGCCGATGGC

Product: N-acetylglucosamine-6-phosphate deacetylase

Products: NA

Alternate protein names: GlcNAc 6-P deacetylase [H]

Number of amino acids: Translated: 383; Mature: 382

Protein sequence:

>383_residues
MARKIFIGARIFDGERFHDDKALIVADGRVEAIAAGNDLPDGETVTLAGGVLSAGFIDAQVNGGAGRMLNDEPSAASMAI
IAGGHRPYGTTSLLPTLITDTSEASIAAIEAATEAVKANRGVAGLHLEGPHLAPARKGAHLAELMRPVEDRDLKAFIRAR
EAIGTLLVTMAAEQVTVAQVRELAEGGVTVSIGHSDCSSEAAEERFDAGARGVTHLFNAMSQMGHRAPGLVGAAIDHPST
WCGIIADGHHVDPKALRTALRAKRGEGKLFFVTDAMSLVGSEKDSFTLNGRTVRRERGGFCSKLVLSDGTLAGSDVDMIS
TIRYGVTYLDLTLAEALRMATLYPARFLRLADRGHLSPGARADLVHLTDALTVTATWLAGETA

Sequences:

>Translated_383_residues
MARKIFIGARIFDGERFHDDKALIVADGRVEAIAAGNDLPDGETVTLAGGVLSAGFIDAQVNGGAGRMLNDEPSAASMAI
IAGGHRPYGTTSLLPTLITDTSEASIAAIEAATEAVKANRGVAGLHLEGPHLAPARKGAHLAELMRPVEDRDLKAFIRAR
EAIGTLLVTMAAEQVTVAQVRELAEGGVTVSIGHSDCSSEAAEERFDAGARGVTHLFNAMSQMGHRAPGLVGAAIDHPST
WCGIIADGHHVDPKALRTALRAKRGEGKLFFVTDAMSLVGSEKDSFTLNGRTVRRERGGFCSKLVLSDGTLAGSDVDMIS
TIRYGVTYLDLTLAEALRMATLYPARFLRLADRGHLSPGARADLVHLTDALTVTATWLAGETA
>Mature_382_residues
ARKIFIGARIFDGERFHDDKALIVADGRVEAIAAGNDLPDGETVTLAGGVLSAGFIDAQVNGGAGRMLNDEPSAASMAII
AGGHRPYGTTSLLPTLITDTSEASIAAIEAATEAVKANRGVAGLHLEGPHLAPARKGAHLAELMRPVEDRDLKAFIRARE
AIGTLLVTMAAEQVTVAQVRELAEGGVTVSIGHSDCSSEAAEERFDAGARGVTHLFNAMSQMGHRAPGLVGAAIDHPSTW
CGIIADGHHVDPKALRTALRAKRGEGKLFFVTDAMSLVGSEKDSFTLNGRTVRRERGGFCSKLVLSDGTLAGSDVDMIST
IRYGVTYLDLTLAEALRMATLYPARFLRLADRGHLSPGARADLVHLTDALTVTATWLAGETA

Specific function: N-acetylglucosamine utilization. [C]

COG id: COG1820

COG function: function code G; N-acetylglucosamine-6-phosphate deacetylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the nagA family [H]

Homologues:

Organism=Homo sapiens, GI21361513, Length=416, Percent_Identity=31.9711538461538, Blast_Score=140, Evalue=1e-33,
Organism=Homo sapiens, GI224922791, Length=415, Percent_Identity=32.0481927710843, Blast_Score=137, Evalue=1e-32,
Organism=Escherichia coli, GI1786892, Length=378, Percent_Identity=39.1534391534392, Blast_Score=222, Evalue=3e-59,
Organism=Caenorhabditis elegans, GI17553768, Length=356, Percent_Identity=33.7078651685393, Blast_Score=134, Evalue=7e-32,
Organism=Drosophila melanogaster, GI281361140, Length=402, Percent_Identity=34.0796019900498, Blast_Score=178, Evalue=7e-45,
Organism=Drosophila melanogaster, GI19920392, Length=392, Percent_Identity=34.1836734693878, Blast_Score=174, Evalue=9e-44,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006680
- InterPro:   IPR003764
- InterPro:   IPR011059 [H]

Pfam domain/function: PF01979 Amidohydro_1 [H]

EC number: =3.5.1.25 [H]

Molecular weight: Translated: 40252; Mature: 40121

Theoretical pI: Translated: 6.32; Mature: 6.32

Prosite motif: PS01070 NUCLEASE_NON_SPEC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MARKIFIGARIFDGERFHDDKALIVADGRVEAIAAGNDLPDGETVTLAGGVLSAGFIDAQ
CCCEEEEEEEEECCCEECCCCEEEEECCCEEEEECCCCCCCCCEEEEECCCCCCCEEEEE
VNGGAGRMLNDEPSAASMAIIAGGHRPYGTTSLLPTLITDTSEASIAAIEAATEAVKANR
ECCCCCCCCCCCCCCCEEEEEECCCCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHCC
GVAGLHLEGPHLAPARKGAHLAELMRPVEDRDLKAFIRAREAIGTLLVTMAAEQVTVAQV
CEEEEEECCCCCCCCCCCCHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RELAEGGVTVSIGHSDCSSEAAEERFDAGARGVTHLFNAMSQMGHRAPGLVGAAIDHPST
HHHHHCCEEEEECCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCEEEECCCCCC
WCGIIADGHHVDPKALRTALRAKRGEGKLFFVTDAMSLVGSEKDSFTLNGRTVRRERGGF
EEEEEECCCCCCHHHHHHHHHHCCCCCCEEEEEEHHHHHCCCCCCEEECCEEEEHHCCCC
CSKLVLSDGTLAGSDVDMISTIRYGVTYLDLTLAEALRMATLYPARFLRLADRGHLSPGA
EEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
RADLVHLTDALTVTATWLAGETA
CCCCEEEHHHHEEEEEEECCCCC
>Mature Secondary Structure 
ARKIFIGARIFDGERFHDDKALIVADGRVEAIAAGNDLPDGETVTLAGGVLSAGFIDAQ
CCEEEEEEEEECCCEECCCCEEEEECCCEEEEECCCCCCCCCEEEEECCCCCCCEEEEE
VNGGAGRMLNDEPSAASMAIIAGGHRPYGTTSLLPTLITDTSEASIAAIEAATEAVKANR
ECCCCCCCCCCCCCCCEEEEEECCCCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHCC
GVAGLHLEGPHLAPARKGAHLAELMRPVEDRDLKAFIRAREAIGTLLVTMAAEQVTVAQV
CEEEEEECCCCCCCCCCCCHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RELAEGGVTVSIGHSDCSSEAAEERFDAGARGVTHLFNAMSQMGHRAPGLVGAAIDHPST
HHHHHCCEEEEECCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCEEEECCCCCC
WCGIIADGHHVDPKALRTALRAKRGEGKLFFVTDAMSLVGSEKDSFTLNGRTVRRERGGF
EEEEEECCCCCCHHHHHHHHHHCCCCCCEEEEEEHHHHHCCCCCCEEECCEEEEHHCCCC
CSKLVLSDGTLAGSDVDMISTIRYGVTYLDLTLAEALRMATLYPARFLRLADRGHLSPGA
EEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
RADLVHLTDALTVTATWLAGETA
CCCCEEEHHHHEEEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9301118; 10952301 [H]