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The map label for this gene is cyaB [H]

Identifier: 209550936

GI number: 209550936

Start: 3469229

End: 3471400

Strand: Reverse

Name: cyaB [H]

Synonym: Rleg2_3360

Alternate gene names: 209550936

Gene position: 3471400-3469229 (Counterclockwise)

Preceding gene: 209550942

Following gene: 209550934

Centisome position: 76.5

GC content: 63.72

Gene sequence:

>2172_bases
ATGACGCGCGTCCAGCAAATCGGTGTCGTTATCGGCCTGGCGATCGTGGCTCTGCTCACGATCCTGCGGGCCGATGATCC
CGGGATTTTCAAGCTGATCCGCGGCGTGACTTTCGATGAATATCAGCGGCTCGTTCCAAGGACCTTCGAGCCGATGCCGG
TTCGCGTGATCGACATCGACGAGGCATCCTTACGCGAATTCGGCCAATGGCCCTGGCCGCGGGACCGGATGGCGCTGCTG
GTGGATCGGCTTTCGGCGATGGGCGCTTCGGCCATCGCCTTCGATATTCTGTTCGCCGAGCCGGACCGGCTGTCGCCGCG
CAACGTTGTCGCCGAGGTCGCAGGCGTCGATCCTTCGCTGGCCGAGAAACTGCCTGACAATGACGAGATATTCGCCCGCG
CGATTGCCGAGAAGCCCGTCGTGCTCGGCTTCGGCCTTTCCAATGTGGGCAATTACCGGCCGCCTGTGAAGGCGGGTTTC
GCCTTCACAGGCGAAAGCCCCATTTCCGCGCCGCCCTATCTCGGCGCCTCGACGCCGCTCAGGCCGCAATTGGAGGCGAA
TGCGGCGGGGCTCGGCCATATCAGCCTCAACCCCGGCAACCCTTCGCCGGTGGTGCGGGCGGTGCCGCTGTTTTTGACCG
ACGGCGAGCAGCTCTATCCCAATCTCGCCATTGAGGCGCTACGCGTTGCGCAGGGGGCGTCGACCTATGTGCTGTCAGGC
GCGCCCGATCGCGCCGGCATCATGACATCGGCGAAAATCGGCGATTTTGTTGTGCCGCTGACGGCGGCGGGCGAACTCTG
GCTCTATGTCAGCCCTGATCGGGCCGAGCGGTACATATCCGCTCGGCAGGTGCTTGCGGCCGGAGGGGCCTCTCCCGAGG
TCGCGGCCGCCATTGACGGCAGCATCGTCTTCGTCGGCACATCGGCTGCCGGCCTGCAGGACATCCGCGTCACGGCGCTC
GGCGAGAACGTTCCCGGCGTGTCGCTACATGCCCAGGCGGTCGAGCAGATCCTGTCCGGCCATTTCCTGTCGCGGCCCGA
CTGGGCCGACGGGCTGGAAATCCTGACCATTGCCGTGCTCGGATGCCTGCTCGTCGTGGTGACGACCTTCGTCAGTCCCG
CCGTCGCGCTGATCTGCGGCCTGCTGATCACGGCGATGGCGCTCGTAGCCTCCTGGTCGTCGTTTCTGTATGCCGGGCTT
CTTTTCGATCCGCTGGCGCCGATCGTCAGCGGATCGATCATCCATTTTGCCGCAACCTCGTTCAAAATCCTGGTGATCGA
CCGGGAGCGGCGGGCGGTGCGGCGTGCCTTCGGGCATTATCTTTCGCCATCGCTGCTCCATCGTATCGAGCATACCCGCG
ATCCATTGCGCCTCGGCGGCGACGACCGCGAACTGACGGTCATGTTCGTCGATGTCCGAAACTTCACCGAGATCAGCGAG
CGGTTGGCGCCGACCGATGTCGTCGCCTTCCTGAACACGCTGCTCGATGCGCTGAGCCGCCACGTGGTGGCCAATGAAGG
CACGCTCGACAAGTTCATCGGCGATTCCATCATGGCGTTCTGGAATGCGCCCGTCGATGTGGCCGATCATGAAACCAAGG
CGGTTCGCGCAGCGCTTGCCATGCGCGAGACGCTCGCCGAATTGAACGCCGGCGACGCTTTCGGCTTTGGACCGGGACAA
CAGGTCGGGATCGGCATCGGCATCCATACCGGCCTTGCCTGCGTCGGCAACATGGGCGCCAAGACGCGCTTCAACTATTC
GGCGGTCGGCGATGCCGTCAATGTCGCGGCACGTCTGGAATCATGCTGCAAGGAAGTCGGCTTCGATATTCTGATATCCG
ACAGCACGGCAAGGTCGGTGCGGGGTATGGCGCTGCTCGAGGCCGGCGCCATTCCGCTCAAAGGAAAGAGCAGCCGAACG
CAGATCCTTGCCGTCGTCGGCGACGAACGCGTTGCCGCATCGGCCGAATTTTCAGCCCTTGTCGTCACCCACCAGCAGTT
GATGCAGGCCCTGCTTGCGCATTCGAAGAACACCCGCAAGCTTATCGGCGCGGCAAAGCTCGGGGCCGCGGGAGTGATCG
ACGGCCTGGCGGAATTCTACCAGCGGGTATCCGGCAGGAGCGATCATTTTCGCGAGGCGAATGATCGATTCGAGAAGAGC
GCGGCCGACTGA

Upstream 100 bases:

>100_bases
TCCGAACGGCATGTGCGAATGGCGTTTGGACCGAAAGCGGCGTAGCCTGCCGGCAGGTGCGGGCCGTTTATGCGGGCCGT
GGAGGGACACCGGTGAGATC

Downstream 100 bases:

>100_bases
ACGGTCAGCGGTTGTGATTGAAACTCCCGCCCCTGTTGTGGTGCCGATCCCTATCGTGATCGTGATCACGATCGCCATCG
CCATCGTGTCCTTGATGATC

Product: adenylate/guanylate cyclase with Chase sensor

Products: NA

Alternate protein names: ATP pyrophosphate-lyase 2; Adenylyl cyclase 2; AC2 [H]

Number of amino acids: Translated: 723; Mature: 722

Protein sequence:

>723_residues
MTRVQQIGVVIGLAIVALLTILRADDPGIFKLIRGVTFDEYQRLVPRTFEPMPVRVIDIDEASLREFGQWPWPRDRMALL
VDRLSAMGASAIAFDILFAEPDRLSPRNVVAEVAGVDPSLAEKLPDNDEIFARAIAEKPVVLGFGLSNVGNYRPPVKAGF
AFTGESPISAPPYLGASTPLRPQLEANAAGLGHISLNPGNPSPVVRAVPLFLTDGEQLYPNLAIEALRVAQGASTYVLSG
APDRAGIMTSAKIGDFVVPLTAAGELWLYVSPDRAERYISARQVLAAGGASPEVAAAIDGSIVFVGTSAAGLQDIRVTAL
GENVPGVSLHAQAVEQILSGHFLSRPDWADGLEILTIAVLGCLLVVVTTFVSPAVALICGLLITAMALVASWSSFLYAGL
LFDPLAPIVSGSIIHFAATSFKILVIDRERRAVRRAFGHYLSPSLLHRIEHTRDPLRLGGDDRELTVMFVDVRNFTEISE
RLAPTDVVAFLNTLLDALSRHVVANEGTLDKFIGDSIMAFWNAPVDVADHETKAVRAALAMRETLAELNAGDAFGFGPGQ
QVGIGIGIHTGLACVGNMGAKTRFNYSAVGDAVNVAARLESCCKEVGFDILISDSTARSVRGMALLEAGAIPLKGKSSRT
QILAVVGDERVAASAEFSALVVTHQQLMQALLAHSKNTRKLIGAAKLGAAGVIDGLAEFYQRVSGRSDHFREANDRFEKS
AAD

Sequences:

>Translated_723_residues
MTRVQQIGVVIGLAIVALLTILRADDPGIFKLIRGVTFDEYQRLVPRTFEPMPVRVIDIDEASLREFGQWPWPRDRMALL
VDRLSAMGASAIAFDILFAEPDRLSPRNVVAEVAGVDPSLAEKLPDNDEIFARAIAEKPVVLGFGLSNVGNYRPPVKAGF
AFTGESPISAPPYLGASTPLRPQLEANAAGLGHISLNPGNPSPVVRAVPLFLTDGEQLYPNLAIEALRVAQGASTYVLSG
APDRAGIMTSAKIGDFVVPLTAAGELWLYVSPDRAERYISARQVLAAGGASPEVAAAIDGSIVFVGTSAAGLQDIRVTAL
GENVPGVSLHAQAVEQILSGHFLSRPDWADGLEILTIAVLGCLLVVVTTFVSPAVALICGLLITAMALVASWSSFLYAGL
LFDPLAPIVSGSIIHFAATSFKILVIDRERRAVRRAFGHYLSPSLLHRIEHTRDPLRLGGDDRELTVMFVDVRNFTEISE
RLAPTDVVAFLNTLLDALSRHVVANEGTLDKFIGDSIMAFWNAPVDVADHETKAVRAALAMRETLAELNAGDAFGFGPGQ
QVGIGIGIHTGLACVGNMGAKTRFNYSAVGDAVNVAARLESCCKEVGFDILISDSTARSVRGMALLEAGAIPLKGKSSRT
QILAVVGDERVAASAEFSALVVTHQQLMQALLAHSKNTRKLIGAAKLGAAGVIDGLAEFYQRVSGRSDHFREANDRFEKS
AAD
>Mature_722_residues
TRVQQIGVVIGLAIVALLTILRADDPGIFKLIRGVTFDEYQRLVPRTFEPMPVRVIDIDEASLREFGQWPWPRDRMALLV
DRLSAMGASAIAFDILFAEPDRLSPRNVVAEVAGVDPSLAEKLPDNDEIFARAIAEKPVVLGFGLSNVGNYRPPVKAGFA
FTGESPISAPPYLGASTPLRPQLEANAAGLGHISLNPGNPSPVVRAVPLFLTDGEQLYPNLAIEALRVAQGASTYVLSGA
PDRAGIMTSAKIGDFVVPLTAAGELWLYVSPDRAERYISARQVLAAGGASPEVAAAIDGSIVFVGTSAAGLQDIRVTALG
ENVPGVSLHAQAVEQILSGHFLSRPDWADGLEILTIAVLGCLLVVVTTFVSPAVALICGLLITAMALVASWSSFLYAGLL
FDPLAPIVSGSIIHFAATSFKILVIDRERRAVRRAFGHYLSPSLLHRIEHTRDPLRLGGDDRELTVMFVDVRNFTEISER
LAPTDVVAFLNTLLDALSRHVVANEGTLDKFIGDSIMAFWNAPVDVADHETKAVRAALAMRETLAELNAGDAFGFGPGQQ
VGIGIGIHTGLACVGNMGAKTRFNYSAVGDAVNVAARLESCCKEVGFDILISDSTARSVRGMALLEAGAIPLKGKSSRTQ
ILAVVGDERVAASAEFSALVVTHQQLMQALLAHSKNTRKLIGAAKLGAAGVIDGLAEFYQRVSGRSDHFREANDRFEKSA
AD

Specific function: Unknown

COG id: COG4252

COG function: function code T; Predicted transmembrane sensor domain

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Drosophila melanogaster, GI62484298, Length=213, Percent_Identity=27.2300469483568, Blast_Score=83, Evalue=6e-16,
Organism=Drosophila melanogaster, GI62484477, Length=213, Percent_Identity=27.2300469483568, Blast_Score=83, Evalue=6e-16,
Organism=Drosophila melanogaster, GI116008008, Length=213, Percent_Identity=27.2300469483568, Blast_Score=82, Evalue=1e-15,
Organism=Drosophila melanogaster, GI161078020, Length=217, Percent_Identity=28.5714285714286, Blast_Score=71, Evalue=3e-12,
Organism=Drosophila melanogaster, GI85725044, Length=357, Percent_Identity=26.3305322128852, Blast_Score=70, Evalue=6e-12,
Organism=Drosophila melanogaster, GI221330468, Length=178, Percent_Identity=29.2134831460674, Blast_Score=66, Evalue=7e-11,
Organism=Drosophila melanogaster, GI221330470, Length=178, Percent_Identity=29.2134831460674, Blast_Score=66, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR011006
- InterPro:   IPR001789 [H]

Pfam domain/function: PF00211 Guanylate_cyc; PF00072 Response_reg [H]

EC number: =4.6.1.1 [H]

Molecular weight: Translated: 76973; Mature: 76842

Theoretical pI: Translated: 5.66; Mature: 5.66

Prosite motif: PS50125 GUANYLATE_CYCLASES_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRVQQIGVVIGLAIVALLTILRADDPGIFKLIRGVTFDEYQRLVPRTFEPMPVRVIDID
CCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCHHHHHHHCCCCCCCCCEEEEECC
EASLREFGQWPWPRDRMALLVDRLSAMGASAIAFDILFAEPDRLSPRNVVAEVAGVDPSL
HHHHHHHCCCCCCHHHHHHHHHHHHHCCCHHHEEEEEECCCCCCCHHHHHHHHHCCCHHH
AEKLPDNDEIFARAIAEKPVVLGFGLSNVGNYRPPVKAGFAFTGESPISAPPYLGASTPL
HHHCCCCHHHHHHHHHCCCEEEEECHHCCCCCCCCCCCCEEECCCCCCCCCCCCCCCCCC
RPQLEANAAGLGHISLNPGNPSPVVRAVPLFLTDGEQLYPNLAIEALRVAQGASTYVLSG
CCCCCCCCCCEEEEEECCCCCCCHHEEEEEEEECCHHHHHHHHHHHHHHHCCCCEEEEEC
APDRAGIMTSAKIGDFVVPLTAAGELWLYVSPDRAERYISARQVLAAGGASPEVAAAIDG
CCCCCCCEEECCCCCEEEEEECCCCEEEEECCHHHHHHHHHHHHHHCCCCCCCEEEEECC
SIVFVGTSAAGLQDIRVTALGENVPGVSLHAQAVEQILSGHFLSRPDWADGLEILTIAVL
CEEEEECCCCCCCEEEEEEECCCCCCCCHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHH
GCLLVVVTTFVSPAVALICGLLITAMALVASWSSFLYAGLLFDPLAPIVSGSIIHFAATS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECC
FKILVIDRERRAVRRAFGHYLSPSLLHRIEHTRDPLRLGGDDRELTVMFVDVRNFTEISE
EEEEEEECHHHHHHHHHHHCCCHHHHHHHHHCCCCHHCCCCCCEEEEEEEECHHHHHHHH
RLAPTDVVAFLNTLLDALSRHVVANEGTLDKFIGDSIMAFWNAPVDVADHETKAVRAALA
HCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHH
MRETLAELNAGDAFGFGPGQQVGIGIGIHTGLACVGNMGAKTRFNYSAVGDAVNVAARLE
HHHHHHHCCCCCCCCCCCCCCEEEEEEHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHH
SCCKEVGFDILISDSTARSVRGMALLEAGAIPLKGKSSRTQILAVVGDERVAASAEFSAL
HHHHHCCCEEEEECCHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEECCCHHCCCCCHHHH
VVTHQQLMQALLAHSKNTRKLIGAAKLGAAGVIDGLAEFYQRVSGRSDHFREANDRFEKS
HHHHHHHHHHHHHCCCCCHHHHHHHHHCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHC
AAD
CCC
>Mature Secondary Structure 
TRVQQIGVVIGLAIVALLTILRADDPGIFKLIRGVTFDEYQRLVPRTFEPMPVRVIDID
CCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCHHHHHHHCCCCCCCCCEEEEECC
EASLREFGQWPWPRDRMALLVDRLSAMGASAIAFDILFAEPDRLSPRNVVAEVAGVDPSL
HHHHHHHCCCCCCHHHHHHHHHHHHHCCCHHHEEEEEECCCCCCCHHHHHHHHHCCCHHH
AEKLPDNDEIFARAIAEKPVVLGFGLSNVGNYRPPVKAGFAFTGESPISAPPYLGASTPL
HHHCCCCHHHHHHHHHCCCEEEEECHHCCCCCCCCCCCCEEECCCCCCCCCCCCCCCCCC
RPQLEANAAGLGHISLNPGNPSPVVRAVPLFLTDGEQLYPNLAIEALRVAQGASTYVLSG
CCCCCCCCCCEEEEEECCCCCCCHHEEEEEEEECCHHHHHHHHHHHHHHHCCCCEEEEEC
APDRAGIMTSAKIGDFVVPLTAAGELWLYVSPDRAERYISARQVLAAGGASPEVAAAIDG
CCCCCCCEEECCCCCEEEEEECCCCEEEEECCHHHHHHHHHHHHHHCCCCCCCEEEEECC
SIVFVGTSAAGLQDIRVTALGENVPGVSLHAQAVEQILSGHFLSRPDWADGLEILTIAVL
CEEEEECCCCCCCEEEEEEECCCCCCCCHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHH
GCLLVVVTTFVSPAVALICGLLITAMALVASWSSFLYAGLLFDPLAPIVSGSIIHFAATS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECC
FKILVIDRERRAVRRAFGHYLSPSLLHRIEHTRDPLRLGGDDRELTVMFVDVRNFTEISE
EEEEEEECHHHHHHHHHHHCCCHHHHHHHHHCCCCHHCCCCCCEEEEEEEECHHHHHHHH
RLAPTDVVAFLNTLLDALSRHVVANEGTLDKFIGDSIMAFWNAPVDVADHETKAVRAALA
HCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHH
MRETLAELNAGDAFGFGPGQQVGIGIGIHTGLACVGNMGAKTRFNYSAVGDAVNVAARLE
HHHHHHHCCCCCCCCCCCCCCEEEEEEHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHH
SCCKEVGFDILISDSTARSVRGMALLEAGAIPLKGKSSRTQILAVVGDERVAASAEFSAL
HHHHHCCCEEEEECCHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEECCCHHCCCCCHHHH
VVTHQQLMQALLAHSKNTRKLIGAAKLGAAGVIDGLAEFYQRVSGRSDHFREANDRFEKS
HHHHHHHHHHHHHCCCCCHHHHHHHHHCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHC
AAD
CCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9523018; 8418825 [H]