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The map label for this gene is pntB [H]

Identifier: 209550942

GI number: 209550942

Start: 3477252

End: 3478646

Strand: Reverse

Name: pntB [H]

Synonym: Rleg2_3366

Alternate gene names: 209550942

Gene position: 3478646-3477252 (Counterclockwise)

Preceding gene: 209550943

Following gene: 209550936

Centisome position: 76.66

GC content: 62.44

Gene sequence:

>1395_bases
ATGACCAATATCGCAGCCTTCCTCTACCTCGTCTCCGGCGTTCTCTTCATCCTGGCGCTGCGGGGTCTCTCGCATCCTGC
CACCAGCCGCAAGGGCAATCTCTACGGCATGATCGGCATGGGGATCGCCATCCTGACGACGCTGGTGCTGGCGACGCCGA
ATTTCGGCGGTTTCGTGCTGATCATCCTCGGCCTTGCCATCGGCGGCAGCGTCGGCGCCTATGTCGCCCGCACCATCGCC
ATGACCTCGATGCCGCAGCTCGTTGCCGGTTTCCATTCGCTGGTCGGCCTTGCCGCCGTCTTGGTCGCGGCCTCGGCGCT
CTATACCCCCGCCTCCTTCGGCATCGGCGAGATCGGCCAGATCCACACCGAGGCGCGGGTCGAAATGGCGCTCGGCGTGG
CCATCGGTGCGCTGACCTTCACCGGTTCGATCATCGCCTTCCTGAAACTTGACGGGCGCATGTCCGGCAAGCCGATCATG
CTGCCTTACCGGCATCTGATCAATGCGGCGCTGCTGGTGCTGATCGTGCTGTTCATCATCGGGCTTGCCGCCACCGAAAG
TCATTTCGATTTCTGGGCCGTGGTGGCGCTGTCGCTGGCGCTCGGCGTTCTGCTGATCGTGCCGATCGGCGGCGCCGATA
TGCCCGTCGTCGTCTCGATGCTGAATTCCTACTCCGGCTGGGCTGCCGCCGGTATCGGCTTCACGCTCGGCAATCTGGCG
CTGATCATTACCGGCGCGCTTGTCGGTTCGTCCGGCGCGATCCTCTCCTACATCATGTGCAAGGGCATGAACCGTTCCTT
CGTCTCCGTCATCCTCGGCGGTTTCGGCGGCGAGACGGCGTCCAGCGGGCCCGACACCTCAGACAAGACGGTCAAGCTCG
GCTCGGCCGAGGATGCGGCCTATCTGATGGCCAATGCATCGAAGGTCATCATCGTGCCGGGATACGGCATGGCGGTCGCC
CAGGCCCAGCATGCTCTGCGCGAACTCGCCGACAATCTGAAGAAGAACGGCGTCGAAGTGAAATATGCGATCCACCCGGT
CGCAGGCCGCATGCCCGGCCATATGAACGTGCTGCTCGCCGAAGCCAATGTTCCCTATGACGAGGTCTTCGAGCTCGAGG
ACATCAATTCGGAATTTGCCCAGGCCGACGTCGCCTATGTCATCGGCGCCAACGACGTCACCAATCCGGCGGCGCGCGAC
GACAAGACCTCGCCGATCTACGGCATGCCGATCCTCGACGTCGACCGGGCAAAGACCTGCCTCTTCGTCAAGCGCTCGCT
CGGCTCCGGTTATGCCGGCATCGACAATACGCTGTTCTATAAGGACGGCACGATGATGCTGCTCGGTGACGCGAAGAAGA
TGACCGAGGATATCAACAAGGCGATTTCGCATTGA

Upstream 100 bases:

>100_bases
TTCGTCGCCCTCGTGCTCGTCTCGGTGAACATTTTCGGCGGCTTCCTCGTGACGCAGCGAATGCTCTCGATGTACCGCAA
GAAAGACCGGTGAGGAACCG

Downstream 100 bases:

>100_bases
TCGACCGCTAAACAGCCGCCCTCGGGCGGCTGTTCGGTTCAGCTCGGAGCCGCTTTGCTCAGGTCTCCCCCGGCACCAGC
GTCATCTTCTCGACGCCGAT

Product: NAD(P)(+) transhydrogenase

Products: NA

Alternate protein names: Nicotinamide nucleotide transhydrogenase subunit beta; Proton-translocating transhydrogenase NADP(H)-binding component; Pyridine nucleotide transhydrogenase subunit beta; dIII [H]

Number of amino acids: Translated: 464; Mature: 463

Protein sequence:

>464_residues
MTNIAAFLYLVSGVLFILALRGLSHPATSRKGNLYGMIGMGIAILTTLVLATPNFGGFVLIILGLAIGGSVGAYVARTIA
MTSMPQLVAGFHSLVGLAAVLVAASALYTPASFGIGEIGQIHTEARVEMALGVAIGALTFTGSIIAFLKLDGRMSGKPIM
LPYRHLINAALLVLIVLFIIGLAATESHFDFWAVVALSLALGVLLIVPIGGADMPVVVSMLNSYSGWAAAGIGFTLGNLA
LIITGALVGSSGAILSYIMCKGMNRSFVSVILGGFGGETASSGPDTSDKTVKLGSAEDAAYLMANASKVIIVPGYGMAVA
QAQHALRELADNLKKNGVEVKYAIHPVAGRMPGHMNVLLAEANVPYDEVFELEDINSEFAQADVAYVIGANDVTNPAARD
DKTSPIYGMPILDVDRAKTCLFVKRSLGSGYAGIDNTLFYKDGTMMLLGDAKKMTEDINKAISH

Sequences:

>Translated_464_residues
MTNIAAFLYLVSGVLFILALRGLSHPATSRKGNLYGMIGMGIAILTTLVLATPNFGGFVLIILGLAIGGSVGAYVARTIA
MTSMPQLVAGFHSLVGLAAVLVAASALYTPASFGIGEIGQIHTEARVEMALGVAIGALTFTGSIIAFLKLDGRMSGKPIM
LPYRHLINAALLVLIVLFIIGLAATESHFDFWAVVALSLALGVLLIVPIGGADMPVVVSMLNSYSGWAAAGIGFTLGNLA
LIITGALVGSSGAILSYIMCKGMNRSFVSVILGGFGGETASSGPDTSDKTVKLGSAEDAAYLMANASKVIIVPGYGMAVA
QAQHALRELADNLKKNGVEVKYAIHPVAGRMPGHMNVLLAEANVPYDEVFELEDINSEFAQADVAYVIGANDVTNPAARD
DKTSPIYGMPILDVDRAKTCLFVKRSLGSGYAGIDNTLFYKDGTMMLLGDAKKMTEDINKAISH
>Mature_463_residues
TNIAAFLYLVSGVLFILALRGLSHPATSRKGNLYGMIGMGIAILTTLVLATPNFGGFVLIILGLAIGGSVGAYVARTIAM
TSMPQLVAGFHSLVGLAAVLVAASALYTPASFGIGEIGQIHTEARVEMALGVAIGALTFTGSIIAFLKLDGRMSGKPIML
PYRHLINAALLVLIVLFIIGLAATESHFDFWAVVALSLALGVLLIVPIGGADMPVVVSMLNSYSGWAAAGIGFTLGNLAL
IITGALVGSSGAILSYIMCKGMNRSFVSVILGGFGGETASSGPDTSDKTVKLGSAEDAAYLMANASKVIIVPGYGMAVAQ
AQHALRELADNLKKNGVEVKYAIHPVAGRMPGHMNVLLAEANVPYDEVFELEDINSEFAQADVAYVIGANDVTNPAARDD
KTSPIYGMPILDVDRAKTCLFVKRSLGSGYAGIDNTLFYKDGTMMLLGDAKKMTEDINKAISH

Specific function: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane [H]

COG id: COG1282

COG function: function code C; NAD/NADP transhydrogenase beta subunit

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PNT beta subunit family [H]

Homologues:

Organism=Homo sapiens, GI122939155, Length=472, Percent_Identity=45.3389830508475, Blast_Score=374, Evalue=1e-103,
Organism=Homo sapiens, GI122939153, Length=472, Percent_Identity=45.3389830508475, Blast_Score=374, Evalue=1e-103,
Organism=Escherichia coli, GI1787886, Length=459, Percent_Identity=52.723311546841, Blast_Score=451, Evalue=1e-128,
Organism=Caenorhabditis elegans, GI17550456, Length=461, Percent_Identity=46.4208242950108, Blast_Score=364, Evalue=1e-101,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012136
- InterPro:   IPR004003 [H]

Pfam domain/function: PF02233 PNTB [H]

EC number: =1.6.1.2 [H]

Molecular weight: Translated: 48364; Mature: 48233

Theoretical pI: Translated: 6.60; Mature: 6.60

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTNIAAFLYLVSGVLFILALRGLSHPATSRKGNLYGMIGMGIAILTTLVLATPNFGGFVL
CCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEHHHHHHHHHHHHHHHCCCCCCHHH
IILGLAIGGSVGAYVARTIAMTSMPQLVAGFHSLVGLAAVLVAASALYTPASFGIGEIGQ
HHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHH
IHTEARVEMALGVAIGALTFTGSIIAFLKLDGRMSGKPIMLPYRHLINAALLVLIVLFII
HHHHHHHHHHHHHHHHHHHHHHHEEEEEEECCCCCCCCEEHHHHHHHHHHHHHHHHHHHH
GLAATESHFDFWAVVALSLALGVLLIVPIGGADMPVVVSMLNSYSGWAAAGIGFTLGNLA
HHHCCCCCCHHHHHHHHHHHHHHHEEEECCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHH
LIITGALVGSSGAILSYIMCKGMNRSFVSVILGGFGGETASSGPDTSDKTVKLGSAEDAA
HHHHHHHHCCCCHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCCCCCCCCEEEECCCCCCH
YLMANASKVIIVPGYGMAVAQAQHALRELADNLKKNGVEVKYAIHPVAGRMPGHMNVLLA
HEEECCCEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCEEEEEE
EANVPYDEVFELEDINSEFAQADVAYVIGANDVTNPAARDDKTSPIYGMPILDVDRAKTC
ECCCCHHHHHHHHHCCHHHHHCCEEEEEECCCCCCCCCCCCCCCCEECCCCEECCCCHHH
LFVKRSLGSGYAGIDNTLFYKDGTMMLLGDAKKMTEDINKAISH
HHHHHHCCCCCCCCCCEEEEECCCEEEECCHHHHHHHHHHHHCC
>Mature Secondary Structure 
TNIAAFLYLVSGVLFILALRGLSHPATSRKGNLYGMIGMGIAILTTLVLATPNFGGFVL
CHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEHHHHHHHHHHHHHHHCCCCCCHHH
IILGLAIGGSVGAYVARTIAMTSMPQLVAGFHSLVGLAAVLVAASALYTPASFGIGEIGQ
HHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHH
IHTEARVEMALGVAIGALTFTGSIIAFLKLDGRMSGKPIMLPYRHLINAALLVLIVLFII
HHHHHHHHHHHHHHHHHHHHHHHEEEEEEECCCCCCCCEEHHHHHHHHHHHHHHHHHHHH
GLAATESHFDFWAVVALSLALGVLLIVPIGGADMPVVVSMLNSYSGWAAAGIGFTLGNLA
HHHCCCCCCHHHHHHHHHHHHHHHEEEECCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHH
LIITGALVGSSGAILSYIMCKGMNRSFVSVILGGFGGETASSGPDTSDKTVKLGSAEDAA
HHHHHHHHCCCCHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCCCCCCCCEEEECCCCCCH
YLMANASKVIIVPGYGMAVAQAQHALRELADNLKKNGVEVKYAIHPVAGRMPGHMNVLLA
HEEECCCEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCEEEEEE
EANVPYDEVFELEDINSEFAQADVAYVIGANDVTNPAARDDKTSPIYGMPILDVDRAKTC
ECCCCHHHHHHHHHCCHHHHHCCEEEEEECCCCCCCCCCCCCCCCEECCCCEECCCCHHH
LFVKRSLGSGYAGIDNTLFYKDGTMMLLGDAKKMTEDINKAISH
HHHHHHCCCCCCCCCCEEEEECCCEEEECCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8075801 [H]