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The map label for this gene is ald2 [H]

Identifier: 209549036

GI number: 209549036

Start: 1457720

End: 1458838

Strand: Direct

Name: ald2 [H]

Synonym: Rleg2_1433

Alternate gene names: 209549036

Gene position: 1457720-1458838 (Clockwise)

Preceding gene: 209549031

Following gene: 209549042

Centisome position: 32.12

GC content: 65.33

Gene sequence:

>1119_bases
ATGCGTGTCGGTTGCCCGAAGGAAATCAAGAACCATGAATATCGCGTCGGCCTGACGCCGGCTTCGGTGCGCGAATACGT
CGCCCATGGCCACGAGGTCTGGGTGGAAACGAAGGCGGGCGCCGGGATCGGCGCCGATGACGCCGCCTATGCCGCGGCTG
GCGCGAAGATCGCCGCCTCCGCCAAGGATATCTTCGAAAAATGCGACATGATCGTCAAGGTGAAGGAGCCGCAGCCCTCC
GAATGGGCGCAGCTGCGTGACGGTCAGCTTCTCTATACCTATCTGCATCTGGCGCCCGATCCCGAACAGACCAAGGGTCT
GATCGCCTCCGGTGTCACCGCGATCGCCTATGAAACGGTTACCGACGAGCGCGGCGGCCTGCCGCTGCTGGCGCCGATGT
CGGAGGTTGCCGGCCGCCTGTCGATTCAGGCGGGCGCAACCGCCCTGCAGAAAGCCAATGGCGGCCTCGGCGTCCTGCTC
GGCGGCGTGCCGGGCGTGCTGCCGGGCAAGGTCGCGGTCATCGGCGGCGGTGTCGTCGGTCTGCATGCCGCCAGGATGGC
CGCCGGCCTCGGCGCCGATGTCAGTATCCTCGACAGGTCGCTGCCGCGCCTTCGCCAGCTCGACGACATATTCTCAGGCC
GCGTTCACACCCGTTATTCCAGCATCCAGGCATTGGAGGAGGAGGTCTTCTCCGCCGATCTCATCATCGGCGCCGTGCTG
ATCCCCGGTGCGGCTGCTCCGAAGCTCGTCACCCGCGAGATGCTGTCCGGCATGAAGAAGGGCTCCGTCATCGTCGACGT
CGCCATCGACCAGGGCGGCTGCTTCGAGACCTCGCATGCAACCACCCATTCCGATCCGACCTATGAGGTCGACGGCGTGG
TGCATTATTGCGTCGCCAACATGCCGGGCGCGGTTCCCGTCACCTCGGCGCATGCGCTGAACAATGCGACGCTCGTCCAC
GGCCTGGCGCTTGCCGATCGCGGCCTGCGTGCCATTGCCGAAGACAAGCATCTGAGGAACGGCCTCAATGTGCACAAGGG
CCGCATCACCAACAAGCCGGTCGCCGAGGCGCTCGGCTACGAGGCTTTCGCGCCCGAAAGCGTGCTGAACGTAGCGTAA

Upstream 100 bases:

>100_bases
TTCAGCAAATCGTCTTTGCAAGGACATTTCATCGCCTTGGTGGTTGGATTCATCATCTGAGGAGATCCGCGATTGCGGAG
ATGACATGAGAGGAACGCCA

Downstream 100 bases:

>100_bases
GCTACCTGACTCTGCGTTAGGCGAGGGCGCCGGTCTCCGCAGGGGCTGGCGCCTTTACCTTGTCGATCCGGTATTGAAAG
CAGTTGTTGCGCGCCGAGCG

Product: alanine dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 372; Mature: 372

Protein sequence:

>372_residues
MRVGCPKEIKNHEYRVGLTPASVREYVAHGHEVWVETKAGAGIGADDAAYAAAGAKIAASAKDIFEKCDMIVKVKEPQPS
EWAQLRDGQLLYTYLHLAPDPEQTKGLIASGVTAIAYETVTDERGGLPLLAPMSEVAGRLSIQAGATALQKANGGLGVLL
GGVPGVLPGKVAVIGGGVVGLHAARMAAGLGADVSILDRSLPRLRQLDDIFSGRVHTRYSSIQALEEEVFSADLIIGAVL
IPGAAAPKLVTREMLSGMKKGSVIVDVAIDQGGCFETSHATTHSDPTYEVDGVVHYCVANMPGAVPVTSAHALNNATLVH
GLALADRGLRAIAEDKHLRNGLNVHKGRITNKPVAEALGYEAFAPESVLNVA

Sequences:

>Translated_372_residues
MRVGCPKEIKNHEYRVGLTPASVREYVAHGHEVWVETKAGAGIGADDAAYAAAGAKIAASAKDIFEKCDMIVKVKEPQPS
EWAQLRDGQLLYTYLHLAPDPEQTKGLIASGVTAIAYETVTDERGGLPLLAPMSEVAGRLSIQAGATALQKANGGLGVLL
GGVPGVLPGKVAVIGGGVVGLHAARMAAGLGADVSILDRSLPRLRQLDDIFSGRVHTRYSSIQALEEEVFSADLIIGAVL
IPGAAAPKLVTREMLSGMKKGSVIVDVAIDQGGCFETSHATTHSDPTYEVDGVVHYCVANMPGAVPVTSAHALNNATLVH
GLALADRGLRAIAEDKHLRNGLNVHKGRITNKPVAEALGYEAFAPESVLNVA
>Mature_372_residues
MRVGCPKEIKNHEYRVGLTPASVREYVAHGHEVWVETKAGAGIGADDAAYAAAGAKIAASAKDIFEKCDMIVKVKEPQPS
EWAQLRDGQLLYTYLHLAPDPEQTKGLIASGVTAIAYETVTDERGGLPLLAPMSEVAGRLSIQAGATALQKANGGLGVLL
GGVPGVLPGKVAVIGGGVVGLHAARMAAGLGADVSILDRSLPRLRQLDDIFSGRVHTRYSSIQALEEEVFSADLIIGAVL
IPGAAAPKLVTREMLSGMKKGSVIVDVAIDQGGCFETSHATTHSDPTYEVDGVVHYCVANMPGAVPVTSAHALNNATLVH
GLALADRGLRAIAEDKHLRNGLNVHKGRITNKPVAEALGYEAFAPESVLNVA

Specific function: May play a role in cell wall synthesis as L-alanine is an important constituent of the peptidoglycan layer [H]

COG id: COG0686

COG function: function code E; Alanine dehydrogenase

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AlaDH/PNT family [H]

Homologues:

Organism=Homo sapiens, GI122939155, Length=366, Percent_Identity=29.7814207650273, Blast_Score=124, Evalue=1e-28,
Organism=Homo sapiens, GI122939153, Length=366, Percent_Identity=29.7814207650273, Blast_Score=124, Evalue=1e-28,
Organism=Escherichia coli, GI1787887, Length=378, Percent_Identity=33.0687830687831, Blast_Score=132, Evalue=5e-32,
Organism=Caenorhabditis elegans, GI17550456, Length=372, Percent_Identity=27.6881720430108, Blast_Score=120, Evalue=1e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007698
- InterPro:   IPR008142
- InterPro:   IPR008143
- InterPro:   IPR007886
- InterPro:   IPR008141 [H]

Pfam domain/function: PF01262 AlaDh_PNT_C; PF05222 AlaDh_PNT_N [H]

EC number: =1.4.1.1 [H]

Molecular weight: Translated: 38831; Mature: 38831

Theoretical pI: Translated: 6.57; Mature: 6.57

Prosite motif: PS00837 ALADH_PNT_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRVGCPKEIKNHEYRVGLTPASVREYVAHGHEVWVETKAGAGIGADDAAYAAAGAKIAAS
CCCCCCHHHCCCCEEEECCHHHHHHHHHCCCEEEEEECCCCCCCCCCHHHHHCCCHHHHH
AKDIFEKCDMIVKVKEPQPSEWAQLRDGQLLYTYLHLAPDPEQTKGLIASGVTAIAYETV
HHHHHHHCCEEEEECCCCCHHHHHCCCCCEEEEEEEECCCHHHHHHHHHCCHHHEEEEEE
TDERGGLPLLAPMSEVAGRLSIQAGATALQKANGGLGVLLGGVPGVLPGKVAVIGGGVVG
CCCCCCCCEECCHHHHHHHEEEHHCHHHHHHCCCCEEEEECCCCCCCCCCEEEEECCHHH
LHAARMAAGLGADVSILDRSLPRLRQLDDIFSGRVHTRYSSIQALEEEVFSADLIIGAVL
HHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
IPGAAAPKLVTREMLSGMKKGSVIVDVAIDQGGCFETSHATTHSDPTYEVDGVVHYCVAN
CCCCCCHHHHHHHHHCCCCCCCEEEEEEECCCCCEECCCCCCCCCCCEEHHHHHHHHHHC
MPGAVPVTSAHALNNATLVHGLALADRGLRAIAEDKHLRNGLNVHKGRITNKPVAEALGY
CCCCCCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHCC
EAFAPESVLNVA
CCCCCHHHHCCC
>Mature Secondary Structure
MRVGCPKEIKNHEYRVGLTPASVREYVAHGHEVWVETKAGAGIGADDAAYAAAGAKIAAS
CCCCCCHHHCCCCEEEECCHHHHHHHHHCCCEEEEEECCCCCCCCCCHHHHHCCCHHHHH
AKDIFEKCDMIVKVKEPQPSEWAQLRDGQLLYTYLHLAPDPEQTKGLIASGVTAIAYETV
HHHHHHHCCEEEEECCCCCHHHHHCCCCCEEEEEEEECCCHHHHHHHHHCCHHHEEEEEE
TDERGGLPLLAPMSEVAGRLSIQAGATALQKANGGLGVLLGGVPGVLPGKVAVIGGGVVG
CCCCCCCCEECCHHHHHHHEEEHHCHHHHHHCCCCEEEEECCCCCCCCCCEEEEECCHHH
LHAARMAAGLGADVSILDRSLPRLRQLDDIFSGRVHTRYSSIQALEEEVFSADLIIGAVL
HHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
IPGAAAPKLVTREMLSGMKKGSVIVDVAIDQGGCFETSHATTHSDPTYEVDGVVHYCVAN
CCCCCCHHHHHHHHHCCCCCCCEEEEEEECCCCCEECCCCCCCCCCCEEHHHHHHHHHHC
MPGAVPVTSAHALNNATLVHGLALADRGLRAIAEDKHLRNGLNVHKGRITNKPVAEALGY
CCCCCCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHCC
EAFAPESVLNVA
CCCCCHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA