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The map label for this gene is cysS [H]

Identifier: 209548641

GI number: 209548641

Start: 1056372

End: 1057763

Strand: Reverse

Name: cysS [H]

Synonym: Rleg2_1038

Alternate gene names: 209548641

Gene position: 1057763-1056372 (Counterclockwise)

Preceding gene: 209548644

Following gene: 209548640

Centisome position: 23.31

GC content: 62.43

Gene sequence:

>1392_bases
ATGGGCGGCATGCCGGAACTGAAGCTGTACAATACGCTGACACGGGAAGAAACGGTCTTTGCGCCGATCGATCCGGACAA
TGTCCGCATGTATGTCTGCGGCCCGACCGTCTATGATTTCGCTCATATCGGCAACGCCCGCCCGGTCATCGTCTTCGACG
TGCTGTTCCGGCTGTTGCGCCATGTCTATGGCGAGGATCACGTCACCTATGCCCGCAACATCACGGATGTCGACGACAAG
ATCAATGCGCGGGCGCTGAGGGATCATCCGGGCCTGCCGCTCAATCAAGCGATCCGGGCGGTCACCGAAAGGACCGAGAC
GCAATTTCACGCCGATGTCGCCGAACTCGGCTGCCTGGAGCCAAGCGTCGAGCCGCGGGCGACCGACAATATCGTTGAGA
TGACCGAGATCATCGAGAAGCTGATCGGCAACGGCCATGCCTATGTCGCAGCCGGCGAAGTGCTGTTCGACACCAAGTCC
ATGGCGGATTACGGCCAGCTTTCGAAGCGCCCGCTCGACGAGCAGCAGGCCGGCGCCCGCATCGCCGTCGACGCGCACAA
GAAGAACTCCGGCGATTTCGTGCTGTGGAAACTGTCGAGTCACAATGAACCCGGCTGGGAGAGCCCGTGGGGCCGCGGCC
GGCCGGGCTGGCATATCGAATGCTCGGCGATGAGCAAGCGCTATCTCGGCGACGTCTTCGACATTCATGGCGGCGGGCTG
GACCTGATCTTCCCGCATCATGAAAACGAGATCGCCCAGTCGCGCTGCGCCCACGGCACCGAGGTGATGGCGAATATCTG
GATGCATAACGGCTTCCTGCAGGTGGAAGGCCGCAAGATGTCGAAATCCGAAGGCAATTTCGTTACCATCCACGATCTGC
TGCACACCCAGATTTTCGGCGGCCGCAAATGGCCGGGCGAAGTGCTGCGCCTTGCCATGCTGATGACGCATTACCGCGAG
CCGATCGATTTCTCGATCAAGCGGCTTGAGGAAGCCGAACGCCTGCTCGCCAAATGGCCGGCGACGGAGCCCGGCGATGC
CGAACCTGACGAGACCGTGCTGAACGCACTCGCCGACAACCTCAACACGGTGGCGGCGGTGCAGGCCTTGCACGCACTGG
CGCAAGCTGCCCATACGGATCCCGCCGCCGGCGCCCGTTTTGCCGCAACGGCTGCCCTCCTCGGCCTGCTGCCGAAGAAA
GCCGAAATCGACGAAGCCGTCGCAGCGGCGGTCGATGCGCTGGTCGCCATGCGTCTTGAAATGCTGAAGGCGAAAAACTT
CGCCGAGGCCGACAAGATCCGCGACGAACTGACGGCAAAGGGCATCCAGCTGAAGGACGGCAAGGATGCGGCGACCGGCG
AGCGGGTGACGACCTGGGAGGTCAAGCGGTAG

Upstream 100 bases:

>100_bases
GCGCTGGCCCGGCCGTTTTCGTCTCCCAAATAGTCAAGATGCGAAACGCCCCGGTCCGCCGGTCGCAATATTTTTCTGAT
TGTGCTTATGGGAGAGTGGA

Downstream 100 bases:

>100_bases
GATGGGTTGGTCGGCGACGCATACCCCCCTCTGCCCTGCCGGGCATCTCCCCCACAAGGGGGGAGATCGGCAAGACGCGC
CGGCTTCCCAAGATATCGAC

Product: cysteinyl-tRNA synthetase

Products: NA

Alternate protein names: Cysteine--tRNA ligase; CysRS [H]

Number of amino acids: Translated: 463; Mature: 462

Protein sequence:

>463_residues
MGGMPELKLYNTLTREETVFAPIDPDNVRMYVCGPTVYDFAHIGNARPVIVFDVLFRLLRHVYGEDHVTYARNITDVDDK
INARALRDHPGLPLNQAIRAVTERTETQFHADVAELGCLEPSVEPRATDNIVEMTEIIEKLIGNGHAYVAAGEVLFDTKS
MADYGQLSKRPLDEQQAGARIAVDAHKKNSGDFVLWKLSSHNEPGWESPWGRGRPGWHIECSAMSKRYLGDVFDIHGGGL
DLIFPHHENEIAQSRCAHGTEVMANIWMHNGFLQVEGRKMSKSEGNFVTIHDLLHTQIFGGRKWPGEVLRLAMLMTHYRE
PIDFSIKRLEEAERLLAKWPATEPGDAEPDETVLNALADNLNTVAAVQALHALAQAAHTDPAAGARFAATAALLGLLPKK
AEIDEAVAAAVDALVAMRLEMLKAKNFAEADKIRDELTAKGIQLKDGKDAATGERVTTWEVKR

Sequences:

>Translated_463_residues
MGGMPELKLYNTLTREETVFAPIDPDNVRMYVCGPTVYDFAHIGNARPVIVFDVLFRLLRHVYGEDHVTYARNITDVDDK
INARALRDHPGLPLNQAIRAVTERTETQFHADVAELGCLEPSVEPRATDNIVEMTEIIEKLIGNGHAYVAAGEVLFDTKS
MADYGQLSKRPLDEQQAGARIAVDAHKKNSGDFVLWKLSSHNEPGWESPWGRGRPGWHIECSAMSKRYLGDVFDIHGGGL
DLIFPHHENEIAQSRCAHGTEVMANIWMHNGFLQVEGRKMSKSEGNFVTIHDLLHTQIFGGRKWPGEVLRLAMLMTHYRE
PIDFSIKRLEEAERLLAKWPATEPGDAEPDETVLNALADNLNTVAAVQALHALAQAAHTDPAAGARFAATAALLGLLPKK
AEIDEAVAAAVDALVAMRLEMLKAKNFAEADKIRDELTAKGIQLKDGKDAATGERVTTWEVKR
>Mature_462_residues
GGMPELKLYNTLTREETVFAPIDPDNVRMYVCGPTVYDFAHIGNARPVIVFDVLFRLLRHVYGEDHVTYARNITDVDDKI
NARALRDHPGLPLNQAIRAVTERTETQFHADVAELGCLEPSVEPRATDNIVEMTEIIEKLIGNGHAYVAAGEVLFDTKSM
ADYGQLSKRPLDEQQAGARIAVDAHKKNSGDFVLWKLSSHNEPGWESPWGRGRPGWHIECSAMSKRYLGDVFDIHGGGLD
LIFPHHENEIAQSRCAHGTEVMANIWMHNGFLQVEGRKMSKSEGNFVTIHDLLHTQIFGGRKWPGEVLRLAMLMTHYREP
IDFSIKRLEEAERLLAKWPATEPGDAEPDETVLNALADNLNTVAAVQALHALAQAAHTDPAAGARFAATAALLGLLPKKA
EIDEAVAAAVDALVAMRLEMLKAKNFAEADKIRDELTAKGIQLKDGKDAATGERVTTWEVKR

Specific function: Unknown

COG id: COG0215

COG function: function code J; Cysteinyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI13375695, Length=326, Percent_Identity=40.4907975460123, Blast_Score=229, Evalue=5e-60,
Organism=Homo sapiens, GI10835051, Length=319, Percent_Identity=36.0501567398119, Blast_Score=190, Evalue=3e-48,
Organism=Homo sapiens, GI62240992, Length=319, Percent_Identity=36.0501567398119, Blast_Score=189, Evalue=3e-48,
Organism=Homo sapiens, GI303304987, Length=240, Percent_Identity=40.8333333333333, Blast_Score=189, Evalue=5e-48,
Organism=Homo sapiens, GI21269877, Length=319, Percent_Identity=36.0501567398119, Blast_Score=189, Evalue=5e-48,
Organism=Escherichia coli, GI1786737, Length=475, Percent_Identity=43.3684210526316, Blast_Score=338, Evalue=4e-94,
Organism=Caenorhabditis elegans, GI17509795, Length=246, Percent_Identity=38.2113821138211, Blast_Score=162, Evalue=4e-40,
Organism=Caenorhabditis elegans, GI17509797, Length=246, Percent_Identity=38.2113821138211, Blast_Score=162, Evalue=5e-40,
Organism=Saccharomyces cerevisiae, GI6324082, Length=324, Percent_Identity=34.2592592592593, Blast_Score=183, Evalue=5e-47,
Organism=Drosophila melanogaster, GI19922218, Length=344, Percent_Identity=38.0813953488372, Blast_Score=219, Evalue=2e-57,
Organism=Drosophila melanogaster, GI19922364, Length=251, Percent_Identity=39.8406374501992, Blast_Score=184, Evalue=1e-46,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015803
- InterPro:   IPR014729
- InterPro:   IPR009080 [H]

Pfam domain/function: PF01406 tRNA-synt_1e [H]

EC number: =6.1.1.16 [H]

Molecular weight: Translated: 51270; Mature: 51139

Theoretical pI: Translated: 5.79; Mature: 5.79

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGGMPELKLYNTLTREETVFAPIDPDNVRMYVCGPTVYDFAHIGNARPVIVFDVLFRLLR
CCCCCCCHHHHHHCCCCEEEECCCCCCEEEEEECCCHHHHHHCCCCCCCHHHHHHHHHHH
HVYGEDHVTYARNITDVDDKINARALRDHPGLPLNQAIRAVTERTETQFHADVAELGCLE
HHHCCCCEEEECCCCCCCCCCCCHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCC
PSVEPRATDNIVEMTEIIEKLIGNGHAYVAAGEVLFDTKSMADYGQLSKRPLDEQQAGAR
CCCCCCCCCHHHHHHHHHHHHHCCCCEEEEECCEEECCHHHHHHHHHHCCCCCHHHCCCE
IAVDAHKKNSGDFVLWKLSSHNEPGWESPWGRGRPGWHIECSAMSKRYLGDVFDIHGGGL
EEEEECCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCEEEHHHHHHHHHCCCEEECCCCE
DLIFPHHENEIAQSRCAHGTEVMANIWMHNGFLQVEGRKMSKSEGNFVTIHDLLHTQIFG
EEEECCCCCHHHHHHHCCHHHHHHHHHHCCCEEEECCCCCCCCCCCEEEEHHHHHHHHCC
GRKWPGEVLRLAMLMTHYREPIDFSIKRLEEAERLLAKWPATEPGDAEPDETVLNALADN
CCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHH
LNTVAAVQALHALAQAAHTDPAAGARFAATAALLGLLPKKAEIDEAVAAAVDALVAMRLE
HHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
MLKAKNFAEADKIRDELTAKGIQLKDGKDAATGERVTTWEVKR
HHHHCCCHHHHHHHHHHHHCCEEECCCCCCCCCCCEEEEEECC
>Mature Secondary Structure 
GGMPELKLYNTLTREETVFAPIDPDNVRMYVCGPTVYDFAHIGNARPVIVFDVLFRLLR
CCCCCCHHHHHHCCCCEEEECCCCCCEEEEEECCCHHHHHHCCCCCCCHHHHHHHHHHH
HVYGEDHVTYARNITDVDDKINARALRDHPGLPLNQAIRAVTERTETQFHADVAELGCLE
HHHCCCCEEEECCCCCCCCCCCCHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCC
PSVEPRATDNIVEMTEIIEKLIGNGHAYVAAGEVLFDTKSMADYGQLSKRPLDEQQAGAR
CCCCCCCCCHHHHHHHHHHHHHCCCCEEEEECCEEECCHHHHHHHHHHCCCCCHHHCCCE
IAVDAHKKNSGDFVLWKLSSHNEPGWESPWGRGRPGWHIECSAMSKRYLGDVFDIHGGGL
EEEEECCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCEEEHHHHHHHHHCCCEEECCCCE
DLIFPHHENEIAQSRCAHGTEVMANIWMHNGFLQVEGRKMSKSEGNFVTIHDLLHTQIFG
EEEECCCCCHHHHHHHCCHHHHHHHHHHCCCEEEECCCCCCCCCCCEEEEHHHHHHHHCC
GRKWPGEVLRLAMLMTHYREPIDFSIKRLEEAERLLAKWPATEPGDAEPDETVLNALADN
CCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHH
LNTVAAVQALHALAQAAHTDPAAGARFAATAALLGLLPKKAEIDEAVAAAVDALVAMRLE
HHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
MLKAKNFAEADKIRDELTAKGIQLKDGKDAATGERVTTWEVKR
HHHHCCCHHHHHHHHHHHHCCEEECCCCCCCCCCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA