BacMap

Definition	Rhizobium leguminosarum bv. trifolii WSM2304 chromosome, complete genome.
Accession	NC_011369
Length	4,537,948

Click here to switch to the map view.

The map label for this gene is yciK [H]

Identifier: 209548644

GI number: 209548644

Start: 1059459

End: 1060199

Strand: Reverse

Name: yciK [H]

Synonym: Rleg2_1041

Alternate gene names: 209548644

Gene position: 1060199-1059459 (Counterclockwise)

Preceding gene: 209548645

Following gene: 209548641

Centisome position: 23.36

GC content: 66.53

Gene sequence:

>741_bases
ATGAACATCAATCTTGAAGGCAAGATCGCGCTGGTAACAGGCGCATCGCGCGGCATCGGCTATTTCACGGCGCTGGAGCT
TGCGAAAGCCGGCGCCCATGTGATCGCTTGCGCCCGCACGGTCGGCGGGCTCGAAGATCTCGACGACGCGATCAAGGCGG
TCGGCGGCACGGCGACGCTGGTGCCCTTCGACCTGGCCGACATGAACGCGATCGACGCGCTCGGGGGCTCGATCTTCGAA
CGCTGGGGCAAACTCGATATCCTCGTCGCCAATGCCGGCGTGCTCGGCGTCATCTCGCCGATCGGCCATATCGAGGCGAA
GGTGTTCGAGAAGGTGATGACCATCAACGTCACCGCGACATGGCGGCTGATCCGCTCGGTCGACCCGCTGCTCGCCCGCT
CGGATGCCGGCCGCGCCGTCATCCTCTCATCGGGTGCCGCCCATAAATGCCGCCCCTTCTGGAGCGCCTATTCAGCCTCC
AAGGCCGCCGTCGAGGCGCTGGCCCGGACCTGGGCCGGCGAAAGCCAATCGACGCCGTTGCGCATCACCAGCGTCGATCC
CGGTGCGACCCGCACGGCGATGCGCGCCCAGGCGGTGCCCGGCGAAGATCCGCAGACGCTGCCGCATCCTTCCGAGGTCG
CCAAGGCGATCCTGCCGCTGCTCGGCCCCGGCGTGACCGAGACGGGCAAACTGTTCATCGTGCGGGACAATAAGCTCGCC
GATTACCGGCTGCCGGAATAA

Upstream 100 bases:

>100_bases
ATGCTTGCCAGCAACGGCTGAGCCGCTTCCGTTTTGACTTTCCTATCAGGGGCGCTTATTGCGCCCCTTACCTTTTCAAG
CACAGCCGGGACCGGAGCAG

Downstream 100 bases:

>100_bases
TGTTAATTCCTGATACCTCGTACAGACGAATCGTTTTCAGGCAATTCTTTCGATCCGACAGCGTTCCAAAAGCGGATAGC
TTTCAATAAACGGCTTAAGG

Product: short-chain dehydrogenase/reductase SDR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 246; Mature: 246

Protein sequence:

>246_residues
MNINLEGKIALVTGASRGIGYFTALELAKAGAHVIACARTVGGLEDLDDAIKAVGGTATLVPFDLADMNAIDALGGSIFE
RWGKLDILVANAGVLGVISPIGHIEAKVFEKVMTINVTATWRLIRSVDPLLARSDAGRAVILSSGAAHKCRPFWSAYSAS
KAAVEALARTWAGESQSTPLRITSVDPGATRTAMRAQAVPGEDPQTLPHPSEVAKAILPLLGPGVTETGKLFIVRDNKLA
DYRLPE

Sequences:

>Translated_246_residues
MNINLEGKIALVTGASRGIGYFTALELAKAGAHVIACARTVGGLEDLDDAIKAVGGTATLVPFDLADMNAIDALGGSIFE
RWGKLDILVANAGVLGVISPIGHIEAKVFEKVMTINVTATWRLIRSVDPLLARSDAGRAVILSSGAAHKCRPFWSAYSAS
KAAVEALARTWAGESQSTPLRITSVDPGATRTAMRAQAVPGEDPQTLPHPSEVAKAILPLLGPGVTETGKLFIVRDNKLA
DYRLPE
>Mature_246_residues
MNINLEGKIALVTGASRGIGYFTALELAKAGAHVIACARTVGGLEDLDDAIKAVGGTATLVPFDLADMNAIDALGGSIFE
RWGKLDILVANAGVLGVISPIGHIEAKVFEKVMTINVTATWRLIRSVDPLLARSDAGRAVILSSGAAHKCRPFWSAYSAS
KAAVEALARTWAGESQSTPLRITSVDPGATRTAMRAQAVPGEDPQTLPHPSEVAKAILPLLGPGVTETGKLFIVRDNKLA
DYRLPE

Specific function: Unknown

COG id: COG1028

COG function: function code IQR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI20149619, Length=233, Percent_Identity=30.4721030042918, Blast_Score=90, Evalue=2e-18,
Organism=Homo sapiens, GI32483357, Length=190, Percent_Identity=30.5263157894737, Blast_Score=83, Evalue=2e-16,
Organism=Homo sapiens, GI7657478, Length=214, Percent_Identity=28.9719626168224, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI109715829, Length=221, Percent_Identity=31.6742081447964, Blast_Score=79, Evalue=5e-15,
Organism=Homo sapiens, GI7705925, Length=221, Percent_Identity=29.8642533936652, Blast_Score=77, Evalue=1e-14,
Organism=Homo sapiens, GI142976729, Length=234, Percent_Identity=27.3504273504274, Blast_Score=75, Evalue=6e-14,
Organism=Homo sapiens, GI126723191, Length=189, Percent_Identity=29.1005291005291, Blast_Score=71, Evalue=9e-13,
Organism=Homo sapiens, GI5031737, Length=188, Percent_Identity=26.5957446808511, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI33667109, Length=188, Percent_Identity=26.5957446808511, Blast_Score=69, Evalue=3e-12,
Organism=Homo sapiens, GI157739938, Length=193, Percent_Identity=25.9067357512953, Blast_Score=69, Evalue=3e-12,
Organism=Homo sapiens, GI32455239, Length=211, Percent_Identity=28.9099526066351, Blast_Score=69, Evalue=3e-12,
Organism=Homo sapiens, GI5031765, Length=211, Percent_Identity=28.9099526066351, Blast_Score=69, Evalue=3e-12,
Organism=Homo sapiens, GI4557649, Length=191, Percent_Identity=30.8900523560209, Blast_Score=68, Evalue=6e-12,
Organism=Homo sapiens, GI19923817, Length=238, Percent_Identity=26.890756302521, Blast_Score=68, Evalue=9e-12,
Organism=Homo sapiens, GI7706318, Length=208, Percent_Identity=26.4423076923077, Blast_Score=68, Evalue=9e-12,
Organism=Homo sapiens, GI223718074, Length=170, Percent_Identity=30.5882352941176, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI146231950, Length=216, Percent_Identity=30.0925925925926, Blast_Score=65, Evalue=7e-11,
Organism=Homo sapiens, GI40254986, Length=185, Percent_Identity=29.7297297297297, Blast_Score=64, Evalue=1e-10,
Organism=Escherichia coli, GI1787526, Length=221, Percent_Identity=38.4615384615385, Blast_Score=128, Evalue=4e-31,
Organism=Escherichia coli, GI87082100, Length=222, Percent_Identity=34.2342342342342, Blast_Score=82, Evalue=3e-17,
Organism=Escherichia coli, GI1787335, Length=192, Percent_Identity=30.7291666666667, Blast_Score=77, Evalue=9e-16,
Organism=Escherichia coli, GI2367175, Length=230, Percent_Identity=30.8695652173913, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1787905, Length=231, Percent_Identity=30.3030303030303, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1790717, Length=200, Percent_Identity=28.5, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1786812, Length=241, Percent_Identity=29.045643153527, Blast_Score=75, Evalue=4e-15,
Organism=Escherichia coli, GI1789378, Length=195, Percent_Identity=31.2820512820513, Blast_Score=73, Evalue=1e-14,
Organism=Escherichia coli, GI1786701, Length=185, Percent_Identity=27.5675675675676, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI1787820, Length=180, Percent_Identity=26.6666666666667, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI87082160, Length=211, Percent_Identity=24.6445497630332, Blast_Score=64, Evalue=8e-12,
Organism=Escherichia coli, GI1789208, Length=196, Percent_Identity=27.0408163265306, Blast_Score=63, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17562906, Length=252, Percent_Identity=29.7619047619048, Blast_Score=93, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI17562910, Length=203, Percent_Identity=30.0492610837438, Blast_Score=87, Evalue=8e-18,
Organism=Caenorhabditis elegans, GI17551412, Length=266, Percent_Identity=28.5714285714286, Blast_Score=83, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17538486, Length=259, Percent_Identity=29.7297297297297, Blast_Score=82, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17538480, Length=274, Percent_Identity=28.4671532846715, Blast_Score=82, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI17561402, Length=191, Percent_Identity=27.7486910994764, Blast_Score=82, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI17531453, Length=248, Percent_Identity=29.0322580645161, Blast_Score=81, Evalue=6e-16,
Organism=Caenorhabditis elegans, GI193204405, Length=196, Percent_Identity=33.1632653061224, Blast_Score=79, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17562908, Length=229, Percent_Identity=31.4410480349345, Blast_Score=79, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17560332, Length=196, Percent_Identity=31.1224489795918, Blast_Score=77, Evalue=6e-15,
Organism=Caenorhabditis elegans, GI17560676, Length=218, Percent_Identity=27.9816513761468, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17562904, Length=253, Percent_Identity=26.0869565217391, Blast_Score=76, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17560220, Length=194, Percent_Identity=30.4123711340206, Blast_Score=74, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI71994604, Length=219, Percent_Identity=28.7671232876712, Blast_Score=73, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17565030, Length=188, Percent_Identity=30.3191489361702, Blast_Score=72, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI115534694, Length=194, Percent_Identity=32.4742268041237, Blast_Score=71, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI17563726, Length=228, Percent_Identity=28.5087719298246, Blast_Score=70, Evalue=7e-13,
Organism=Caenorhabditis elegans, GI17568967, Length=248, Percent_Identity=25.4032258064516, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17544670, Length=208, Percent_Identity=27.4038461538462, Blast_Score=68, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17559104, Length=220, Percent_Identity=29.0909090909091, Blast_Score=68, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI17564282, Length=158, Percent_Identity=30.379746835443, Blast_Score=68, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI17555612, Length=224, Percent_Identity=28.5714285714286, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17538182, Length=235, Percent_Identity=28.936170212766, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI72000259, Length=192, Percent_Identity=31.25, Blast_Score=66, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17560150, Length=246, Percent_Identity=27.2357723577236, Blast_Score=65, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI71994600, Length=224, Percent_Identity=25.4464285714286, Blast_Score=64, Evalue=9e-11,
Organism=Caenorhabditis elegans, GI17562990, Length=237, Percent_Identity=26.1603375527426, Blast_Score=64, Evalue=9e-11,
Organism=Saccharomyces cerevisiae, GI6322227, Length=200, Percent_Identity=35, Blast_Score=87, Evalue=3e-18,
Organism=Saccharomyces cerevisiae, GI6323882, Length=228, Percent_Identity=29.8245614035088, Blast_Score=77, Evalue=3e-15,
Organism=Saccharomyces cerevisiae, GI6322226, Length=203, Percent_Identity=30.0492610837438, Blast_Score=73, Evalue=4e-14,
Organism=Saccharomyces cerevisiae, GI6322067, Length=189, Percent_Identity=34.3915343915344, Blast_Score=73, Evalue=5e-14,
Organism=Saccharomyces cerevisiae, GI6322861, Length=235, Percent_Identity=27.6595744680851, Blast_Score=70, Evalue=3e-13,
Organism=Drosophila melanogaster, GI21358495, Length=202, Percent_Identity=30.1980198019802, Blast_Score=91, Evalue=8e-19,
Organism=Drosophila melanogaster, GI24644339, Length=226, Percent_Identity=31.858407079646, Blast_Score=90, Evalue=1e-18,
Organism=Drosophila melanogaster, GI21357041, Length=222, Percent_Identity=31.5315315315315, Blast_Score=88, Evalue=4e-18,
Organism=Drosophila melanogaster, GI28571526, Length=228, Percent_Identity=32.0175438596491, Blast_Score=86, Evalue=3e-17,
Organism=Drosophila melanogaster, GI24648944, Length=231, Percent_Identity=32.9004329004329, Blast_Score=82, Evalue=3e-16,
Organism=Drosophila melanogaster, GI23397609, Length=188, Percent_Identity=34.0425531914894, Blast_Score=79, Evalue=3e-15,
Organism=Drosophila melanogaster, GI21355319, Length=188, Percent_Identity=27.1276595744681, Blast_Score=76, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24643142, Length=202, Percent_Identity=34.1584158415842, Blast_Score=75, Evalue=4e-14,
Organism=Drosophila melanogaster, GI17737361, Length=240, Percent_Identity=28.75, Blast_Score=74, Evalue=9e-14,
Organism=Drosophila melanogaster, GI24641232, Length=229, Percent_Identity=28.82096069869, Blast_Score=72, Evalue=3e-13,
Organism=Drosophila melanogaster, GI116007236, Length=226, Percent_Identity=26.9911504424779, Blast_Score=67, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 25804; Mature: 25804

Theoretical pI: Translated: 7.58; Mature: 7.58

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNINLEGKIALVTGASRGIGYFTALELAKAGAHVIACARTVGGLEDLDDAIKAVGGTATL
CCCCCCCEEEEEECCCCCCHHHHHHHHHHCCHHHEEHHHHHCCHHHHHHHHHHCCCCEEE
VPFDLADMNAIDALGGSIFERWGKLDILVANAGVLGVISPIGHIEAKVFEKVMTINVTAT
EEECCCCCHHHHHHHHHHHHHCCCEEEEEECCCCEEHHCCHHHHHHHHHHHHHEEEEHHH
WRLIRSVDPLLARSDAGRAVILSSGAAHKCRPFWSAYSASKAAVEALARTWAGESQSTPL
HHHHHHCCHHHHCCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCE
RITSVDPGATRTAMRAQAVPGEDPQTLPHPSEVAKAILPLLGPGVTETGKLFIVRDNKLA
EEEECCCCCCHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCEEEEEECCCCC
DYRLPE
CCCCCC
>Mature Secondary Structure
MNINLEGKIALVTGASRGIGYFTALELAKAGAHVIACARTVGGLEDLDDAIKAVGGTATL
CCCCCCCEEEEEECCCCCCHHHHHHHHHHCCHHHEEHHHHHCCHHHHHHHHHHCCCCEEE
VPFDLADMNAIDALGGSIFERWGKLDILVANAGVLGVISPIGHIEAKVFEKVMTINVTAT
EEECCCCCHHHHHHHHHHHHHCCCEEEEEECCCCEEHHCCHHHHHHHHHHHHHEEEEHHH
WRLIRSVDPLLARSDAGRAVILSSGAAHKCRPFWSAYSASKAAVEALARTWAGESQSTPL
HHHHHHCCHHHHCCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCE
RITSVDPGATRTAMRAQAVPGEDPQTLPHPSEVAKAILPLLGPGVTETGKLFIVRDNKLA
EEEECCCCCCHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCEEEEEECCCCC
DYRLPE
CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Oxidoreductases; Acting on the CH-OH group of donors; With NAD or NADP as acceptor [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9097039; 9278503; 1885549 [H]