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The map label for this gene is rcsC [H]

Identifier: 209548103

GI number: 209548103

Start: 510505

End: 512229

Strand: Direct

Name: rcsC [H]

Synonym: Rleg2_0497

Alternate gene names: 209548103

Gene position: 510505-512229 (Clockwise)

Preceding gene: 209548100

Following gene: 209548104

Centisome position: 11.25

GC content: 61.51

Gene sequence:

>1725_bases
ATGAGTGCCGGCTTCGATAAGGCGGACACATCATCGGAAACCGACGGGATTTCCGCCGGGGCCGATCTGCAGACGGCGCT
TTTCGATGTGGTGTGCGACAGCCTTTCGTCAGCTTTCATCATCTATGACAAGAACGATCATCTGATCTTCGCCAGCCGCC
AGACGCTGGAATTCTTCCCGCTGCCGCCCGAGATGCTGAAGCCCGGCACGCGGCTTCGCGATTTCCTCGGCGCGGTTTAC
GACACCGGCATTCGCCAGCAATATGACGTCAAGCAGCGCGGCTCGCTGAGCCGCGAGGACTGGCTGTCGCAGAAAATCGC
CTCGCATTGGCGCGAGCGCTTCGATGCCGTTGAGCGTCATGCTCCCGACAGCTGGGTGCGTTTCGTCAAACGCAGGCTGC
CCGGCGGTTACGGCGTCACCATCATTTCCGATATTTCCGAGGACAAGAAGCGCGAAGAGCAATGGCGCTCGGATCTGGAG
CGGGTGCAGCTCACCGAGGACATTCTCGACAATCTGCCGTTCCCGCTCTTCGTCAAGGACCGCAACCTCACCTATGTCGC
GGTCAATCTCGCCTTCTGCGAGAAATATCAGACGACCGCCGACGAGGTGCTCGGGCGCAAGAGCAGCGACCTTTTTTCCG
TCGAGATCGCCAAGCGCTTCGAAGAGAGCGACCGTCATGTGCTGGAGACCGGCGAGATGTCCGTCTCCCGCCAGCGGCAG
ATCTCCCGCGACGGCATCGAGCGCGATATCGTCAGCCGCAAGCACCGCATCGGCAAGCCGGGCCGCTATTTCCTGGTGTC
GACCATGCAGGATCTGCCGCGCGATGGCGCCGATCTCGACGAGTTCGGCCGGGCCTCGGCGATCACCACCTCAAGCAATC
AAAGCTATCGCCGCGCCTATGTGCCGGTGCCGAGTGCGGTCGAGCGCCGCGAGCCGGCGGCGATGGAAGCGATCGTTCCG
GAGAATTTTTCCGGCCGCAAGGTTCTCGTCGTCACGTCCGACCTTGCCGCTGAGACCGCCGCGCTGCGGACGCTGTCGAA
ATACGGTTTCGAATCCTGCTCGGTCCGCGGCGAGGACGAGGAGGAACGGTTCCTGGAAATCGCCACTTCCTCCGGCATCT
CGCTCGATCTCCTGATCATCGACAACCAGATGGGCATGCGCTGCCTGGAACTATCAGAGCAATACGGCATCCCGGCTCTG
GTCATGGACGGTTTCCAGATCGCCAACGAGCTGACCTTCCAGATCGCCCGCCATTTCAACCGCAACAGCCGCAATGGTGG
CACCGGTGCGGATTCGGATTGGGAAATCAGCATCTCCGACGACGTCGTCGGGCTGCAGGTTCTCGTCGCCGAAGACAATG
ATATCAACCAGATCGTTTTTTCGCAGATCCTCGAAGGCCTTGGTTATCGCCATATGATCGCGGCGACCGGCGATGAAGCC
GTGCGCCTCTGGGCCGAGCACCGGCCGCAGATCGTGCTGATGGATATTTCGCTGCCGGGCTTCAACGGCTTCGAGGCCGC
CCGCCTCATCCGGCAGATGGAAGAAACCGGCGGGACAAGCCACACCCCGATCATCGGTGTGCTCACCCAGGCCTTCGAAC
GGGACCGCGCCGAATGCGTCAAGGCTGGCATGGACGATGTCATCATGAAACCGGTCAGCCCCGATATGCTCGAAGCCGTC
TTCCAGAGGCATCTGCTGGATGAGGTCATGCGGGCGCGAGGCTGA

Upstream 100 bases:

>100_bases
GCGGCGCTGTAGTGTTAAGCCGGTTTTAACATAAAAATGGCATTTCTATTCAAATACCTCCGGAAGCTTTCGAAATCGAA
CAGATGTGGGACGCAACAGC

Downstream 100 bases:

>100_bases
TGCATGTCATCAGGGCCTCTGAGCGGTTGCGGCCAACGGCATAAAAATTAACGACTGTAGCCGGGACCACCGGTCAACTC
CCGGATTCTGGGGTGGTTTT

Product: PAS/PAC sensor protein

Products: NA

Alternate protein names: Capsular synthesis regulator component C [H]

Number of amino acids: Translated: 574; Mature: 573

Protein sequence:

>574_residues
MSAGFDKADTSSETDGISAGADLQTALFDVVCDSLSSAFIIYDKNDHLIFASRQTLEFFPLPPEMLKPGTRLRDFLGAVY
DTGIRQQYDVKQRGSLSREDWLSQKIASHWRERFDAVERHAPDSWVRFVKRRLPGGYGVTIISDISEDKKREEQWRSDLE
RVQLTEDILDNLPFPLFVKDRNLTYVAVNLAFCEKYQTTADEVLGRKSSDLFSVEIAKRFEESDRHVLETGEMSVSRQRQ
ISRDGIERDIVSRKHRIGKPGRYFLVSTMQDLPRDGADLDEFGRASAITTSSNQSYRRAYVPVPSAVERREPAAMEAIVP
ENFSGRKVLVVTSDLAAETAALRTLSKYGFESCSVRGEDEEERFLEIATSSGISLDLLIIDNQMGMRCLELSEQYGIPAL
VMDGFQIANELTFQIARHFNRNSRNGGTGADSDWEISISDDVVGLQVLVAEDNDINQIVFSQILEGLGYRHMIAATGDEA
VRLWAEHRPQIVLMDISLPGFNGFEAARLIRQMEETGGTSHTPIIGVLTQAFERDRAECVKAGMDDVIMKPVSPDMLEAV
FQRHLLDEVMRARG

Sequences:

>Translated_574_residues
MSAGFDKADTSSETDGISAGADLQTALFDVVCDSLSSAFIIYDKNDHLIFASRQTLEFFPLPPEMLKPGTRLRDFLGAVY
DTGIRQQYDVKQRGSLSREDWLSQKIASHWRERFDAVERHAPDSWVRFVKRRLPGGYGVTIISDISEDKKREEQWRSDLE
RVQLTEDILDNLPFPLFVKDRNLTYVAVNLAFCEKYQTTADEVLGRKSSDLFSVEIAKRFEESDRHVLETGEMSVSRQRQ
ISRDGIERDIVSRKHRIGKPGRYFLVSTMQDLPRDGADLDEFGRASAITTSSNQSYRRAYVPVPSAVERREPAAMEAIVP
ENFSGRKVLVVTSDLAAETAALRTLSKYGFESCSVRGEDEEERFLEIATSSGISLDLLIIDNQMGMRCLELSEQYGIPAL
VMDGFQIANELTFQIARHFNRNSRNGGTGADSDWEISISDDVVGLQVLVAEDNDINQIVFSQILEGLGYRHMIAATGDEA
VRLWAEHRPQIVLMDISLPGFNGFEAARLIRQMEETGGTSHTPIIGVLTQAFERDRAECVKAGMDDVIMKPVSPDMLEAV
FQRHLLDEVMRARG
>Mature_573_residues
SAGFDKADTSSETDGISAGADLQTALFDVVCDSLSSAFIIYDKNDHLIFASRQTLEFFPLPPEMLKPGTRLRDFLGAVYD
TGIRQQYDVKQRGSLSREDWLSQKIASHWRERFDAVERHAPDSWVRFVKRRLPGGYGVTIISDISEDKKREEQWRSDLER
VQLTEDILDNLPFPLFVKDRNLTYVAVNLAFCEKYQTTADEVLGRKSSDLFSVEIAKRFEESDRHVLETGEMSVSRQRQI
SRDGIERDIVSRKHRIGKPGRYFLVSTMQDLPRDGADLDEFGRASAITTSSNQSYRRAYVPVPSAVERREPAAMEAIVPE
NFSGRKVLVVTSDLAAETAALRTLSKYGFESCSVRGEDEEERFLEIATSSGISLDLLIIDNQMGMRCLELSEQYGIPALV
MDGFQIANELTFQIARHFNRNSRNGGTGADSDWEISISDDVVGLQVLVAEDNDINQIVFSQILEGLGYRHMIAATGDEAV
RLWAEHRPQIVLMDISLPGFNGFEAARLIRQMEETGGTSHTPIIGVLTQAFERDRAECVKAGMDDVIMKPVSPDMLEAVF
QRHLLDEVMRARG

Specific function: Member of the two-component regulatory system RcsC/RcsB involved in the regulation of the expression of genes involved in colanic acid capsule synthesis. Together with RcsF, RcsC probably functions as a membrane-associated protein kinase that phosphorylat

COG id: COG2202

COG function: function code T; FOG: PAS/PAC domain

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI145693157, Length=127, Percent_Identity=30.7086614173228, Blast_Score=72, Evalue=7e-14,
Organism=Escherichia coli, GI48994928, Length=120, Percent_Identity=33.3333333333333, Blast_Score=67, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR000014
- InterPro:   IPR004358
- InterPro:   IPR019017
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF09456 RcsC; PF00072 Response_reg [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 64604; Mature: 64472

Theoretical pI: Translated: 4.72; Mature: 4.72

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAGFDKADTSSETDGISAGADLQTALFDVVCDSLSSAFIIYDKNDHLIFASRQTLEFFP
CCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCEEEEEECCCCEEEEECCCEEEEC
LPPEMLKPGTRLRDFLGAVYDTGIRQQYDVKQRGSLSREDWLSQKIASHWRERFDAVERH
CCHHHHCCCHHHHHHHHHHHHCCCCCCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHC
APDSWVRFVKRRLPGGYGVTIISDISEDKKREEQWRSDLERVQLTEDILDNLPFPLFVKD
CCHHHHHHHHHHCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEC
RNLTYVAVNLAFCEKYQTTADEVLGRKSSDLFSVEIAKRFEESDRHVLETGEMSVSRQRQ
CCEEEEEEEHHHHHHHHCCHHHHHCCCCCCHHHHHHHHHHHHCCCHHHHCCCHHHHHHHH
ISRDGIERDIVSRKHRIGKPGRYFLVSTMQDLPRDGADLDEFGRASAITTSSNQSYRRAY
HHHCCHHHHHHHHHHHCCCCCCEEEEEHHHHCCCCCCCHHHHCCCCEEEECCCCCCCEEE
VPVPSAVERREPAAMEAIVPENFSGRKVLVVTSDLAAETAALRTLSKYGFESCSVRGEDE
CCCCHHHHHCCCCHHHHCCCCCCCCCEEEEEECCHHHHHHHHHHHHHHCCCCCCCCCCCH
EERFLEIATSSGISLDLLIIDNQMGMRCLELSEQYGIPALVMDGFQIANELTFQIARHFN
HHHHHHHHCCCCCEEEEEEECCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHC
RNSRNGGTGADSDWEISISDDVVGLQVLVAEDNDINQIVFSQILEGLGYRHMIAATGDEA
CCCCCCCCCCCCCEEEEECCCCEEEEEEEECCCCHHHHHHHHHHHHCCCEEEEEECCHHH
VRLWAEHRPQIVLMDISLPGFNGFEAARLIRQMEETGGTSHTPIIGVLTQAFERDRAECV
HHHHHHCCCEEEEEEEECCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHH
KAGMDDVIMKPVSPDMLEAVFQRHLLDEVMRARG
HCCCHHHHCCCCCHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SAGFDKADTSSETDGISAGADLQTALFDVVCDSLSSAFIIYDKNDHLIFASRQTLEFFP
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCEEEEEECCCCEEEEECCCEEEEC
LPPEMLKPGTRLRDFLGAVYDTGIRQQYDVKQRGSLSREDWLSQKIASHWRERFDAVERH
CCHHHHCCCHHHHHHHHHHHHCCCCCCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHC
APDSWVRFVKRRLPGGYGVTIISDISEDKKREEQWRSDLERVQLTEDILDNLPFPLFVKD
CCHHHHHHHHHHCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEC
RNLTYVAVNLAFCEKYQTTADEVLGRKSSDLFSVEIAKRFEESDRHVLETGEMSVSRQRQ
CCEEEEEEEHHHHHHHHCCHHHHHCCCCCCHHHHHHHHHHHHCCCHHHHCCCHHHHHHHH
ISRDGIERDIVSRKHRIGKPGRYFLVSTMQDLPRDGADLDEFGRASAITTSSNQSYRRAY
HHHCCHHHHHHHHHHHCCCCCCEEEEEHHHHCCCCCCCHHHHCCCCEEEECCCCCCCEEE
VPVPSAVERREPAAMEAIVPENFSGRKVLVVTSDLAAETAALRTLSKYGFESCSVRGEDE
CCCCHHHHHCCCCHHHHCCCCCCCCCEEEEEECCHHHHHHHHHHHHHHCCCCCCCCCCCH
EERFLEIATSSGISLDLLIIDNQMGMRCLELSEQYGIPALVMDGFQIANELTFQIARHFN
HHHHHHHHCCCCCEEEEEEECCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHC
RNSRNGGTGADSDWEISISDDVVGLQVLVAEDNDINQIVFSQILEGLGYRHMIAATGDEA
CCCCCCCCCCCCCEEEEECCCCEEEEEEEECCCCHHHHHHHHHHHHCCCEEEEEECCHHH
VRLWAEHRPQIVLMDISLPGFNGFEAARLIRQMEETGGTSHTPIIGVLTQAFERDRAECV
HHHHHHCCCEEEEEEEECCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHH
KAGMDDVIMKPVSPDMLEAVFQRHLLDEVMRARG
HCCCHHHHCCCCCHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2404948; 8366025; 9097040; 9278503; 11758943; 11309126; 13129944 [H]