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The map label for this gene is dppC [H]

Identifier: 209548000

GI number: 209548000

Start: 406025

End: 406915

Strand: Direct

Name: dppC [H]

Synonym: Rleg2_0392

Alternate gene names: 209548000

Gene position: 406025-406915 (Clockwise)

Preceding gene: 209547999

Following gene: 209548001

Centisome position: 8.95

GC content: 63.3

Gene sequence:

>891_bases
ATGAGCACCGTCACCGTCAAAACCGGTCAGCCATCCGCTCTTGCGGAGTTCTGGCATTATTTCTCCCGCAACAAGGGCGC
CGTCATCGGCCTCGTCGTCTTCGTCATTATCCTGGTCGTCGCAGTCTTCGCGCCGGTCTTTGCGCCGCATACGCCGAACG
AGCAGAACCGCCAGGTGCTCTTGGCCGTGCCGGCCTGGATGGAAGGCGGCAGCATCTCGTTCCCGCTCGGAACCGATGCC
GTCGGCCGCGATATCCTTTCGCGACTGATCTACGGCGCGCGCTTCTCGCTCTTCATCGGCGTCGTCGTCGTCACCCTTTC
GGTCGTCTGCGGCGTTCTGATCGGTCTCGTCGCCGGCTATTTTCGCGGCAAGGTCGATACGGCGATCATGCGGCTGATGG
ATATCATCCTGGCCTTCCCGTCACTGCTGCTCGCCCTCGTGCTCGTGGCCGTGCTCGGCCCAGGCCTTACCAATGCGATG
ATCGCGATTTCGCTGGTCAACCAGCCGCATTTCGTGCGGCTGACGCGCGCCTCCGTCATCACAGAGCGCGAGAAGGAATA
TGTGATCGCCTCGCGTGTTGCCGGCGCCGGCACCTTCCGCCTGATGTTCAAGACCATCCTGCCGAACTGTCTTGGGCCGC
TGATCGTCCAGGCGACGCTCGCCTTCTCCGCCGCGATCCTCGACGCCGCCGCCCTCGGCTTTCTCGGCATGGGCGCTCAG
CCCCCGACACCCGAATGGGGCACGATGCTCGCTGAATCCCGCGAGTTTATCTCGCGCGCCTGGTGGGTCGTAACATTCCC
GGGCCTTGCCATCCTCATCACCGTTCTCGCCATCAATCTGATGGGTGACGGCCTGCGCGATGCGCTTGACCCCAAGCTGA
AGAGGTCGTGA

Upstream 100 bases:

>100_bases
CGGCCTACTGCTGATCGCCGGCGTCATCATGCTGGTCAATCTGATTGTTGATGTCCTCTATGGCTTCATCAATCCGCGCA
TTCGTCATTAGGAGCGGTTC

Downstream 100 bases:

>100_bases
TGCCACTTCTCGAAATTGAAAATCTGACCGTCGAATTCCAGACCTCTTCAGGTCTTTTCCGCGCTGTCGACCGCGTATCG
CTAGCCTGCGACAAGGGCGA

Product: binding-protein-dependent transporters inner membrane component

Products: ADP; phosphate; dipeptides [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 296; Mature: 295

Protein sequence:

>296_residues
MSTVTVKTGQPSALAEFWHYFSRNKGAVIGLVVFVIILVVAVFAPVFAPHTPNEQNRQVLLAVPAWMEGGSISFPLGTDA
VGRDILSRLIYGARFSLFIGVVVVTLSVVCGVLIGLVAGYFRGKVDTAIMRLMDIILAFPSLLLALVLVAVLGPGLTNAM
IAISLVNQPHFVRLTRASVITEREKEYVIASRVAGAGTFRLMFKTILPNCLGPLIVQATLAFSAAILDAAALGFLGMGAQ
PPTPEWGTMLAESREFISRAWWVVTFPGLAILITVLAINLMGDGLRDALDPKLKRS

Sequences:

>Translated_296_residues
MSTVTVKTGQPSALAEFWHYFSRNKGAVIGLVVFVIILVVAVFAPVFAPHTPNEQNRQVLLAVPAWMEGGSISFPLGTDA
VGRDILSRLIYGARFSLFIGVVVVTLSVVCGVLIGLVAGYFRGKVDTAIMRLMDIILAFPSLLLALVLVAVLGPGLTNAM
IAISLVNQPHFVRLTRASVITEREKEYVIASRVAGAGTFRLMFKTILPNCLGPLIVQATLAFSAAILDAAALGFLGMGAQ
PPTPEWGTMLAESREFISRAWWVVTFPGLAILITVLAINLMGDGLRDALDPKLKRS
>Mature_295_residues
STVTVKTGQPSALAEFWHYFSRNKGAVIGLVVFVIILVVAVFAPVFAPHTPNEQNRQVLLAVPAWMEGGSISFPLGTDAV
GRDILSRLIYGARFSLFIGVVVVTLSVVCGVLIGLVAGYFRGKVDTAIMRLMDIILAFPSLLLALVLVAVLGPGLTNAMI
AISLVNQPHFVRLTRASVITEREKEYVIASRVAGAGTFRLMFKTILPNCLGPLIVQATLAFSAAILDAAALGFLGMGAQP
PTPEWGTMLAESREFISRAWWVVTFPGLAILITVLAINLMGDGLRDALDPKLKRS

Specific function: Part of the binding-protein-dependent transport system for dipeptides; probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG1173

COG function: function code EP; ABC-type dipeptide/oligopeptide/nickel transport systems, permease components

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1789964, Length=284, Percent_Identity=67.6056338028169, Blast_Score=335, Evalue=1e-93,
Organism=Escherichia coli, GI1787760, Length=265, Percent_Identity=44.9056603773585, Blast_Score=225, Evalue=2e-60,
Organism=Escherichia coli, GI1787054, Length=279, Percent_Identity=42.2939068100358, Blast_Score=221, Evalue=4e-59,
Organism=Escherichia coli, GI1787549, Length=288, Percent_Identity=41.6666666666667, Blast_Score=214, Evalue=5e-57,
Organism=Escherichia coli, GI1789889, Length=218, Percent_Identity=42.6605504587156, Blast_Score=167, Evalue=6e-43,
Organism=Escherichia coli, GI1787498, Length=272, Percent_Identity=34.9264705882353, Blast_Score=150, Evalue=6e-38,
Organism=Escherichia coli, GI1788505, Length=218, Percent_Identity=30.2752293577982, Blast_Score=105, Evalue=3e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 31731; Mature: 31600

Theoretical pI: Translated: 10.07; Mature: 10.07

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTVTVKTGQPSALAEFWHYFSRNKGAVIGLVVFVIILVVAVFAPVFAPHTPNEQNRQVL
CCEEEECCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEE
LAVPAWMEGGSISFPLGTDAVGRDILSRLIYGARFSLFIGVVVVTLSVVCGVLIGLVAGY
EEECCCCCCCCEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FRGKVDTAIMRLMDIILAFPSLLLALVLVAVLGPGLTNAMIAISLVNQPHFVRLTRASVI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCEEEEHHHHHH
TEREKEYVIASRVAGAGTFRLMFKTILPNCLGPLIVQATLAFSAAILDAAALGFLGMGAQ
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
PPTPEWGTMLAESREFISRAWWVVTFPGLAILITVLAINLMGDGLRDALDPKLKRS
CCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCHHHHHCCCCCCCC
>Mature Secondary Structure 
STVTVKTGQPSALAEFWHYFSRNKGAVIGLVVFVIILVVAVFAPVFAPHTPNEQNRQVL
CEEEECCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEE
LAVPAWMEGGSISFPLGTDAVGRDILSRLIYGARFSLFIGVVVVTLSVVCGVLIGLVAGY
EEECCCCCCCCEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FRGKVDTAIMRLMDIILAFPSLLLALVLVAVLGPGLTNAMIAISLVNQPHFVRLTRASVI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCEEEEHHHHHH
TEREKEYVIASRVAGAGTFRLMFKTILPNCLGPLIVQATLAFSAAILDAAALGFLGMGAQ
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
PPTPEWGTMLAESREFISRAWWVVTFPGLAILITVLAINLMGDGLRDALDPKLKRS
CCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; dipeptides [Periplasm]; H2O [C]

Specific reaction: ATP + dipeptides [Periplasm] + H2O = ADP + phosphate + dipeptides [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7542800; 8550458 [H]