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The map label for this gene is dppB [H]

Identifier: 209547999

GI number: 209547999

Start: 405011

End: 406015

Strand: Direct

Name: dppB [H]

Synonym: Rleg2_0391

Alternate gene names: 209547999

Gene position: 405011-406015 (Clockwise)

Preceding gene: 209547998

Following gene: 209548000

Centisome position: 8.92

GC content: 59.7

Gene sequence:

>1005_bases
ATGTTGCGTTTTTTCATCGGCCGCCTTGCGGTGCTGATCCCGACATTCCTCGGCGTTTCCCTCATTGCCTTCTCGTTCAT
CCGCATGCTGCCCGGCGATCCCGTCATGCTTTTATCGGGTGAGCGCGTCATGGCGCCGGAACGGCACGCCCAGATCATGC
ACGATCTCGGTTTCGACCGGCCCATGTATGTGCAGTATTTCGATTATCTCGGAAAAGTGCTGCACGGCGATCTCGGCACT
TCGATCGTCACCAAGCGGCCGGTTCTCGGCGAATTCCTGACGCTGTTTCCGGCAACGCTGGAACTTTCCTTCTGTGCCAT
CATCCTCGCCGTCTGTATTGGCGTGCCCGCCGGCATCTTTGCTGCCGTCAAGCGAGGCACCTGGTTCGATCAGAGCGTGA
TGGGTGTCGCCCTGATCGGTTATTCCATGCCGATCTTCTGGTGGGGCCTGCTGCTGATTATCTTCTTCTCCGGCTATCTC
GGCTGGACGCCTGTTTCCGGCCGCATCTCGCTGATGTATTTCTTCAAGCCGGTCACCGGCTTCATGCTGATCGACAGTCT
GCTGTCCGGCCAGAAGGGGGCATTCGCCTCGGCCGTCAGTTACCTCATTCTGCCGACCATCGTGCTGGCGACCATCCCGC
TCGCCGTCATTGCGCGCCAGACGCGTTCGGCAATGCTCGAGGTGCTCGGCGAAGACTATGTCCGCACGGCCCGCTCGAAA
GGCCTGAAGCCGCTGCGCGTCGTCGGCGTGCACGCGCTGCGCAATGCGATGATCCCGGTCATCACCACCATCGGTCTGCA
GATCGGTGTTCTTCTGGCCGGCGCCATCCTCACCGAGACGATCTTCTCCTGGCCGGGCATTGGCAAATGGATGGTCGACT
CGGTCTTCAAGCGTGACTACGCCGTGGTCCAGGGCGGCCTACTGCTGATCGCCGGCGTCATCATGCTGGTCAATCTGATT
GTTGATGTCCTCTATGGCTTCATCAATCCGCGCATTCGTCATTAG

Upstream 100 bases:

>100_bases
CGTATCCGAATAACAAGAAAAATGTAAGAATGCCCGGCAGAGCTGGGCGCAGCCGGCGGTCAGGCACCCCCTGACCGCCG
GAAACTATTGGACATCTGCC

Downstream 100 bases:

>100_bases
GAGCGGTTCATGAGCACCGTCACCGTCAAAACCGGTCAGCCATCCGCTCTTGCGGAGTTCTGGCATTATTTCTCCCGCAA
CAAGGGCGCCGTCATCGGCC

Product: nickel-transporting ATPase

Products: ADP; phosphate; dipeptides [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 334; Mature: 334

Protein sequence:

>334_residues
MLRFFIGRLAVLIPTFLGVSLIAFSFIRMLPGDPVMLLSGERVMAPERHAQIMHDLGFDRPMYVQYFDYLGKVLHGDLGT
SIVTKRPVLGEFLTLFPATLELSFCAIILAVCIGVPAGIFAAVKRGTWFDQSVMGVALIGYSMPIFWWGLLLIIFFSGYL
GWTPVSGRISLMYFFKPVTGFMLIDSLLSGQKGAFASAVSYLILPTIVLATIPLAVIARQTRSAMLEVLGEDYVRTARSK
GLKPLRVVGVHALRNAMIPVITTIGLQIGVLLAGAILTETIFSWPGIGKWMVDSVFKRDYAVVQGGLLLIAGVIMLVNLI
VDVLYGFINPRIRH

Sequences:

>Translated_334_residues
MLRFFIGRLAVLIPTFLGVSLIAFSFIRMLPGDPVMLLSGERVMAPERHAQIMHDLGFDRPMYVQYFDYLGKVLHGDLGT
SIVTKRPVLGEFLTLFPATLELSFCAIILAVCIGVPAGIFAAVKRGTWFDQSVMGVALIGYSMPIFWWGLLLIIFFSGYL
GWTPVSGRISLMYFFKPVTGFMLIDSLLSGQKGAFASAVSYLILPTIVLATIPLAVIARQTRSAMLEVLGEDYVRTARSK
GLKPLRVVGVHALRNAMIPVITTIGLQIGVLLAGAILTETIFSWPGIGKWMVDSVFKRDYAVVQGGLLLIAGVIMLVNLI
VDVLYGFINPRIRH
>Mature_334_residues
MLRFFIGRLAVLIPTFLGVSLIAFSFIRMLPGDPVMLLSGERVMAPERHAQIMHDLGFDRPMYVQYFDYLGKVLHGDLGT
SIVTKRPVLGEFLTLFPATLELSFCAIILAVCIGVPAGIFAAVKRGTWFDQSVMGVALIGYSMPIFWWGLLLIIFFSGYL
GWTPVSGRISLMYFFKPVTGFMLIDSLLSGQKGAFASAVSYLILPTIVLATIPLAVIARQTRSAMLEVLGEDYVRTARSK
GLKPLRVVGVHALRNAMIPVITTIGLQIGVLLAGAILTETIFSWPGIGKWMVDSVFKRDYAVVQGGLLLIAGVIMLVNLI
VDVLYGFINPRIRH

Specific function: Part of the binding-protein-dependent transport system for dipeptides; probably responsible for the translocation of the substrate across the membrane [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1789965, Length=337, Percent_Identity=60.5341246290801, Blast_Score=433, Evalue=1e-123,
Organism=Escherichia coli, GI1787053, Length=338, Percent_Identity=43.1952662721894, Blast_Score=256, Evalue=2e-69,
Organism=Escherichia coli, GI1787761, Length=318, Percent_Identity=48.1132075471698, Blast_Score=244, Evalue=7e-66,
Organism=Escherichia coli, GI1789888, Length=336, Percent_Identity=38.6904761904762, Blast_Score=220, Evalue=1e-58,
Organism=Escherichia coli, GI1787550, Length=269, Percent_Identity=37.9182156133829, Blast_Score=215, Evalue=3e-57,
Organism=Escherichia coli, GI1787497, Length=335, Percent_Identity=35.2238805970149, Blast_Score=196, Evalue=1e-51,
Organism=Escherichia coli, GI1788504, Length=372, Percent_Identity=27.4193548387097, Blast_Score=131, Evalue=7e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 36702; Mature: 36702

Theoretical pI: Translated: 10.04; Mature: 10.04

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLRFFIGRLAVLIPTFLGVSLIAFSFIRMLPGDPVMLLSGERVMAPERHAQIMHDLGFDR
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCHHHHHHHHHCCCCC
PMYVQYFDYLGKVLHGDLGTSIVTKRPVLGEFLTLFPATLELSFCAIILAVCIGVPAGIF
CHHHHHHHHHHHHHHCCCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHH
AAVKRGTWFDQSVMGVALIGYSMPIFWWGLLLIIFFSGYLGWTPVSGRISLMYFFKPVTG
HHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEHHHHHHHH
FMLIDSLLSGQKGAFASAVSYLILPTIVLATIPLAVIARQTRSAMLEVLGEDYVRTARSK
HHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GLKPLRVVGVHALRNAMIPVITTIGLQIGVLLAGAILTETIFSWPGIGKWMVDSVFKRDY
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHH
AVVQGGLLLIAGVIMLVNLIVDVLYGFINPRIRH
HHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MLRFFIGRLAVLIPTFLGVSLIAFSFIRMLPGDPVMLLSGERVMAPERHAQIMHDLGFDR
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCHHHHHHHHHCCCCC
PMYVQYFDYLGKVLHGDLGTSIVTKRPVLGEFLTLFPATLELSFCAIILAVCIGVPAGIF
CHHHHHHHHHHHHHHCCCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHH
AAVKRGTWFDQSVMGVALIGYSMPIFWWGLLLIIFFSGYLGWTPVSGRISLMYFFKPVTG
HHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEHHHHHHHH
FMLIDSLLSGQKGAFASAVSYLILPTIVLATIPLAVIARQTRSAMLEVLGEDYVRTARSK
HHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GLKPLRVVGVHALRNAMIPVITTIGLQIGVLLAGAILTETIFSWPGIGKWMVDSVFKRDY
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHH
AVVQGGLLLIAGVIMLVNLIVDVLYGFINPRIRH
HHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; dipeptides [Periplasm]; H2O [C]

Specific reaction: ATP + dipeptides [Periplasm] + H2O = ADP + phosphate + dipeptides [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]