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The map label for this gene is neuA [H]

Identifier: 209696405

GI number: 209696405

Start: 3262582

End: 3263835

Strand: Direct

Name: neuA [H]

Synonym: VSAL_I3012

Alternate gene names: 209696405

Gene position: 3262582-3263835 (Clockwise)

Preceding gene: 209696404

Following gene: 209696406

Centisome position: 98.12

GC content: 37.88

Gene sequence:

>1254_bases
TTGACTCTCAAGAAGATAGCGATTATTCCAGCGCGCTCGGGTTCGAAAGGGCTAGCTAATAAAAATATTTTAATGTTATT
AGACAAGCCATTGATTGCCTATACCATCGAAGCTGCAATAGATTCTGATATCTTCGAGAGAGTCATAGTGTCAACCGACT
CGCAAGAATACAAGAGTATTGCCGAGCAATATGGTGCAGAAGTGATGATGCGTAGCGACGCGTTAGCATCTGATAGTGCA
ACCTCATTCATGGTCATTGAGGATATTTTGCAAAAAGTATCTGGTTTTGATTATTTTGTATTATTGCAGCCAACGTCCCC
CTTTCGTCACGGCGCACACATTAAAGACGCTGCATTACTTTTTGAGCAGTCAGATTATGCGAATTTTTTGGTTTCGGTAG
CAGAGAGTGGCAAAAGTGCTGATTTAATTAAGCCGATAGATACAGATTTAAGCCTGCAGTATTTTGACTTAGATTTTAGT
AATTATCGCCGCCAAAACAGTAAAGAATATAGTCCTAATGGCGCGATATTTATTGGTCGTAATCAAGAATACTTAAGTAA
AAAACATTTCTTTGGTGCTGATAGTATTGCTTATATTATGAATAAAGCGGATTCAGTCGATATTGATGATAAGTTAGACT
TTGAGTTAGCTATTAGTATTCAACAGCAAAAAAATAAGCAGCAGATCCTATTAAAGTCAATTCATCAGCGTATTGCCGAA
AAGCAGTCTACAATGAATGCCGCATTACCTATCACGTTAATTGGCCACTCAATTTTTGATTATTGGGATATTGATGCATT
AAATAGCCTACAGGTAAATAACTTAGGTATTGCTGGTATTAGCAGCAAAGAGTATTTAGATTTTATCTTGACGCCGAATT
TACTTACTCAGTTAGGTGATAAAGTGGTGCTGTTTGCCGGCACTAATGACATTGTTATTGATGGCTGGACACCAGCATTA
ACACTGCAGTGGATCACTGAAATTATCAATATATTAGCTGATATTAATCCAAATGTTGAGATTTACTTGCTTTCAGTGCC
ACCTGTGCGAGGACGGATCGATCGCAACAACGCTGTGATCAATGAATTAAATGATTATCTTCACGAGCACCTAACCAATG
TGAGCTGGGTGGCATTAAGTTCAGCGTTTTATGACCAATTTGGTAATTTACCAGCAGAATTTACACATGATGGTTTACAT
TTTTCTCCAGAAGCATATCAACAATTAGAGCAAGAAATAGCGGAAGCCCTGTAA

Upstream 100 bases:

>100_bases
ATGTCTTGGTATGAGGTGTTAGGTAAAACGGCAGAACAAGACTTCAGTGAAGATCAATTAATTGCACATTCTGAATTTGT
AGCACAAGAGGTATAACAAA

Downstream 100 bases:

>100_bases
TGAAAAGACTACTTTATATCACAGGCTCTAGAGCTGAATACGGCATTATGAAGCGACTATTACTGGCACTAAAAGATGAC
AGTGAGATTGAATTAACCAT

Product: N-acylneuraminate cytidylyltransferase

Products: NA

Alternate protein names: CMP-N-acetylneuraminic acid synthase; CMP-NeuNAc synthase [H]

Number of amino acids: Translated: 417; Mature: 416

Protein sequence:

>417_residues
MTLKKIAIIPARSGSKGLANKNILMLLDKPLIAYTIEAAIDSDIFERVIVSTDSQEYKSIAEQYGAEVMMRSDALASDSA
TSFMVIEDILQKVSGFDYFVLLQPTSPFRHGAHIKDAALLFEQSDYANFLVSVAESGKSADLIKPIDTDLSLQYFDLDFS
NYRRQNSKEYSPNGAIFIGRNQEYLSKKHFFGADSIAYIMNKADSVDIDDKLDFELAISIQQQKNKQQILLKSIHQRIAE
KQSTMNAALPITLIGHSIFDYWDIDALNSLQVNNLGIAGISSKEYLDFILTPNLLTQLGDKVVLFAGTNDIVIDGWTPAL
TLQWITEIINILADINPNVEIYLLSVPPVRGRIDRNNAVINELNDYLHEHLTNVSWVALSSAFYDQFGNLPAEFTHDGLH
FSPEAYQQLEQEIAEAL

Sequences:

>Translated_417_residues
MTLKKIAIIPARSGSKGLANKNILMLLDKPLIAYTIEAAIDSDIFERVIVSTDSQEYKSIAEQYGAEVMMRSDALASDSA
TSFMVIEDILQKVSGFDYFVLLQPTSPFRHGAHIKDAALLFEQSDYANFLVSVAESGKSADLIKPIDTDLSLQYFDLDFS
NYRRQNSKEYSPNGAIFIGRNQEYLSKKHFFGADSIAYIMNKADSVDIDDKLDFELAISIQQQKNKQQILLKSIHQRIAE
KQSTMNAALPITLIGHSIFDYWDIDALNSLQVNNLGIAGISSKEYLDFILTPNLLTQLGDKVVLFAGTNDIVIDGWTPAL
TLQWITEIINILADINPNVEIYLLSVPPVRGRIDRNNAVINELNDYLHEHLTNVSWVALSSAFYDQFGNLPAEFTHDGLH
FSPEAYQQLEQEIAEAL
>Mature_416_residues
TLKKIAIIPARSGSKGLANKNILMLLDKPLIAYTIEAAIDSDIFERVIVSTDSQEYKSIAEQYGAEVMMRSDALASDSAT
SFMVIEDILQKVSGFDYFVLLQPTSPFRHGAHIKDAALLFEQSDYANFLVSVAESGKSADLIKPIDTDLSLQYFDLDFSN
YRRQNSKEYSPNGAIFIGRNQEYLSKKHFFGADSIAYIMNKADSVDIDDKLDFELAISIQQQKNKQQILLKSIHQRIAEK
QSTMNAALPITLIGHSIFDYWDIDALNSLQVNNLGIAGISSKEYLDFILTPNLLTQLGDKVVLFAGTNDIVIDGWTPALT
LQWITEIINILADINPNVEIYLLSVPPVRGRIDRNNAVINELNDYLHEHLTNVSWVALSSAFYDQFGNLPAEFTHDGLHF
SPEAYQQLEQEIAEAL

Specific function: Unknown

COG id: COG2755

COG function: function code E; Lysophospholipase L1 and related esterases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CMP-NeuNAc synthase family [H]

Homologues:

Organism=Homo sapiens, GI8923900, Length=220, Percent_Identity=31.8181818181818, Blast_Score=88, Evalue=1e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003329
- InterPro:   IPR013830
- InterPro:   IPR013831 [H]

Pfam domain/function: PF02348 CTP_transf_3 [H]

EC number: =2.7.7.43 [H]

Molecular weight: Translated: 46712; Mature: 46581

Theoretical pI: Translated: 4.45; Mature: 4.45

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLKKIAIIPARSGSKGLANKNILMLLDKPLIAYTIEAAIDSDIFERVIVSTDSQEYKSI
CCCEEEEEEECCCCCCCCCCCCEEEEECCCCEEEEEHHHHHHHHHHHHHHCCCCHHHHHH
AEQYGAEVMMRSDALASDSATSFMVIEDILQKVSGFDYFVLLQPTSPFRHGAHIKDAALL
HHHCCCCEEEECCCCCCCCCCHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCHHHHE
FEQSDYANFLVSVAESGKSADLIKPIDTDLSLQYFDLDFSNYRRQNSKEYSPNGAIFIGR
EECCCHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEECCHHHHHCCCCCCCCCCCCEEEEC
NQEYLSKKHFFGADSIAYIMNKADSVDIDDKLDFELAISIQQQKNKQQILLKSIHQRIAE
CHHHHHHHHCCCCCHHHHHHCCCCCCCCCCCCCEEEEEEEHHHCCHHHHHHHHHHHHHHH
KQSTMNAALPITLIGHSIFDYWDIDALNSLQVNNLGIAGISSKEYLDFILTPNLLTQLGD
HHHHCCCCCEEEECCCHHHHHCCCCCCCCEEECCCEEECCCCHHHEEEEECCHHHHHCCC
KVVLFAGTNDIVIDGWTPALTLQWITEIINILADINPNVEIYLLSVPPVRGRIDRNNAVI
EEEEEECCCCEEEECCCHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCCCCHHHH
NELNDYLHEHLTNVSWVALSSAFYDQFGNLPAEFTHDGLHFSPEAYQQLEQEIAEAL
HHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCHHCCCCCCCCHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TLKKIAIIPARSGSKGLANKNILMLLDKPLIAYTIEAAIDSDIFERVIVSTDSQEYKSI
CCEEEEEEECCCCCCCCCCCCEEEEECCCCEEEEEHHHHHHHHHHHHHHCCCCHHHHHH
AEQYGAEVMMRSDALASDSATSFMVIEDILQKVSGFDYFVLLQPTSPFRHGAHIKDAALL
HHHCCCCEEEECCCCCCCCCCHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCHHHHE
FEQSDYANFLVSVAESGKSADLIKPIDTDLSLQYFDLDFSNYRRQNSKEYSPNGAIFIGR
EECCCHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEECCHHHHHCCCCCCCCCCCCEEEEC
NQEYLSKKHFFGADSIAYIMNKADSVDIDDKLDFELAISIQQQKNKQQILLKSIHQRIAE
CHHHHHHHHCCCCCHHHHHHCCCCCCCCCCCCCEEEEEEEHHHCCHHHHHHHHHHHHHHH
KQSTMNAALPITLIGHSIFDYWDIDALNSLQVNNLGIAGISSKEYLDFILTPNLLTQLGD
HHHHCCCCCEEEECCCHHHHHCCCCCCCCEEECCCEEECCCCHHHEEEEECCHHHHHCCC
KVVLFAGTNDIVIDGWTPALTLQWITEIINILADINPNVEIYLLSVPPVRGRIDRNNAVI
EEEEEECCCCEEEECCCHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCCCCHHHH
NELNDYLHEHLTNVSWVALSSAFYDQFGNLPAEFTHDGLHFSPEAYQQLEQEIAEAL
HHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCHHCCCCCCCCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2549035 [H]