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The map label for this gene is neuB

Identifier: 209696404

GI number: 209696404

Start: 3261537

End: 3262577

Strand: Direct

Name: neuB

Synonym: VSAL_I3011

Alternate gene names: NA

Gene position: 3261537-3262577 (Clockwise)

Preceding gene: 209696403

Following gene: 209696405

Centisome position: 98.09

GC content: 38.23

Gene sequence:

>1041_bases
ATGAAAAAAATTTACATTGTTGCAGAAATCGGCTGTAACCATAATGGTGATTTTAATTTAGCAAAAAAAATGGTTGATGA
AGCGAAAAAAGCCGGTGTGGATGCGGTAAAATTCCAAACCTTTAAAGCAGACCAACTAATATCTAAATTTGCACCTAAAG
CGGAATACCAAATAAAAGTAACAGGCAACGATGAGTCTCAATTAGAGATGACGCGTAAACTGGAACTACCTTATGATGAA
TTCATTAAGCTAGAAGAATACGCAAAAGAGATCGGCCTTGATGTATTCTCAACGCCATTTGATTTTGATTCGATCGATTT
CTTGGCATCTCGTGAGCAAAAAACCTGGAAGATCCCATCGGGTGAGCTATTAAATCTGCCTTATTTAGAAAAAATTGCCC
GTTTGCCAATTGCAGGCAAAGAGATTGTCATTTCGACCGGTATGGCTACCGTGGAAGAGATTCAGCTAGCACTGGATGTG
CTTGCTAAAAATGGTATGAAGCCAGAAGAGATCACTATCCTGCACTGTAATACCGAATACCCAACGGCATTTGAAGATGT
AAACTTAAATTCCATTGCTGGTTTTAAAGAAACTTTTAAGCAATATAAAATTGGTTTTTCGGATCACTCGCCAGGTTATT
TTGCCAGTATAGCATCAGTCCCATACGGTATCACTTTTATTGAAAAGCATTTTACCTTAGATAAGAATTTTCATGGGCCA
GATCATAAAGCTTCGGTAACGCCTGAAGAATTAACATTGTTATGCCAAGGGATCCGTGCGGTTGAGCAAGCATTAGGTAG
CCATGATAAACTGGTGACAAACTCAGAACGTAAAAATAAGATTGTGGCGCGGAAATCGATAGTGGCAAAGTTTGATATTA
AGAAAGGTGATGTGTTTACGCTTGATAACATTACTACTAAAAGACCGGGTAATGGTATTAGCCCTATGTCTTGGTATGAG
GTGTTAGGTAAAACGGCAGAACAAGACTTCAGTGAAGATCAATTAATTGCACATTCTGAATTTGTAGCACAAGAGGTATA
A

Upstream 100 bases:

>100_bases
GGTCGTAATTCGGAACATTAACGATAAGATTGTTGTTGCGGGTTCTCCTACGCATTTAATTCGAGAAATCGTTTAACTAA
TTTAATTAGAGAATAGCATA

Downstream 100 bases:

>100_bases
CAAATTGACTCTCAAGAAGATAGCGATTATTCCAGCGCGCTCGGGTTCGAAAGGGCTAGCTAATAAAAATATTTTAATGT
TATTAGACAAGCCATTGATT

Product: sialic acid synthase NeuB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 346; Mature: 346

Protein sequence:

>346_residues
MKKIYIVAEIGCNHNGDFNLAKKMVDEAKKAGVDAVKFQTFKADQLISKFAPKAEYQIKVTGNDESQLEMTRKLELPYDE
FIKLEEYAKEIGLDVFSTPFDFDSIDFLASREQKTWKIPSGELLNLPYLEKIARLPIAGKEIVISTGMATVEEIQLALDV
LAKNGMKPEEITILHCNTEYPTAFEDVNLNSIAGFKETFKQYKIGFSDHSPGYFASIASVPYGITFIEKHFTLDKNFHGP
DHKASVTPEELTLLCQGIRAVEQALGSHDKLVTNSERKNKIVARKSIVAKFDIKKGDVFTLDNITTKRPGNGISPMSWYE
VLGKTAEQDFSEDQLIAHSEFVAQEV

Sequences:

>Translated_346_residues
MKKIYIVAEIGCNHNGDFNLAKKMVDEAKKAGVDAVKFQTFKADQLISKFAPKAEYQIKVTGNDESQLEMTRKLELPYDE
FIKLEEYAKEIGLDVFSTPFDFDSIDFLASREQKTWKIPSGELLNLPYLEKIARLPIAGKEIVISTGMATVEEIQLALDV
LAKNGMKPEEITILHCNTEYPTAFEDVNLNSIAGFKETFKQYKIGFSDHSPGYFASIASVPYGITFIEKHFTLDKNFHGP
DHKASVTPEELTLLCQGIRAVEQALGSHDKLVTNSERKNKIVARKSIVAKFDIKKGDVFTLDNITTKRPGNGISPMSWYE
VLGKTAEQDFSEDQLIAHSEFVAQEV
>Mature_346_residues
MKKIYIVAEIGCNHNGDFNLAKKMVDEAKKAGVDAVKFQTFKADQLISKFAPKAEYQIKVTGNDESQLEMTRKLELPYDE
FIKLEEYAKEIGLDVFSTPFDFDSIDFLASREQKTWKIPSGELLNLPYLEKIARLPIAGKEIVISTGMATVEEIQLALDV
LAKNGMKPEEITILHCNTEYPTAFEDVNLNSIAGFKETFKQYKIGFSDHSPGYFASIASVPYGITFIEKHFTLDKNFHGP
DHKASVTPEELTLLCQGIRAVEQALGSHDKLVTNSERKNKIVARKSIVAKFDIKKGDVFTLDNITTKRPGNGISPMSWYE
VLGKTAEQDFSEDQLIAHSEFVAQEV

Specific function: Unknown

COG id: COG2089

COG function: function code M; Sialic acid synthase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: To B.subtilis spsE [H]

Homologues:

Organism=Homo sapiens, GI12056473, Length=335, Percent_Identity=34.3283582089552, Blast_Score=187, Evalue=2e-47,
Organism=Drosophila melanogaster, GI21357081, Length=359, Percent_Identity=31.4763231197772, Blast_Score=159, Evalue=3e-39,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006190
- InterPro:   IPR013785
- InterPro:   IPR013132
- InterPro:   IPR013974 [H]

Pfam domain/function: PF03102 NeuB; PF08666 SAF [H]

EC number: NA

Molecular weight: Translated: 38831; Mature: 38831

Theoretical pI: Translated: 5.33; Mature: 5.33

Prosite motif: PS50844 AFP_LIKE ; PS00018 EF_HAND_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKIYIVAEIGCNHNGDFNLAKKMVDEAKKAGVDAVKFQTFKADQLISKFAPKAEYQIKV
CCEEEEEEEECCCCCCCHHHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHCCCCCEEEEE
TGNDESQLEMTRKLELPYDEFIKLEEYAKEIGLDVFSTPFDFDSIDFLASREQKTWKIPS
ECCCHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHCCCCCEEECCC
GELLNLPYLEKIARLPIAGKEIVISTGMATVEEIQLALDVLAKNGMKPEEITILHCNTEY
CCEECCHHHHHHHHCCCCCCEEEEECCCHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCC
PTAFEDVNLNSIAGFKETFKQYKIGFSDHSPGYFASIASVPYGITFIEKHFTLDKNFHGP
CCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHCCCCEEEEEEHEEECCCCCCC
DHKASVTPEELTLLCQGIRAVEQALGSHDKLVTNSERKNKIVARKSIVAKFDIKKGDVFT
CCCCCCCHHHHHHHHHHHHHHHHHHCCCCCEECCCHHHHHHHHHHHHHEEEECCCCCEEE
LDNITTKRPGNGISPMSWYEVLGKTAEQDFSEDQLIAHSEFVAQEV
ECCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCC
>Mature Secondary Structure
MKKIYIVAEIGCNHNGDFNLAKKMVDEAKKAGVDAVKFQTFKADQLISKFAPKAEYQIKV
CCEEEEEEEECCCCCCCHHHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHCCCCCEEEEE
TGNDESQLEMTRKLELPYDEFIKLEEYAKEIGLDVFSTPFDFDSIDFLASREQKTWKIPS
ECCCHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHCCCCCEEECCC
GELLNLPYLEKIARLPIAGKEIVISTGMATVEEIQLALDVLAKNGMKPEEITILHCNTEY
CCEECCHHHHHHHHCCCCCCEEEEECCCHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCC
PTAFEDVNLNSIAGFKETFKQYKIGFSDHSPGYFASIASVPYGITFIEKHFTLDKNFHGP
CCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHCCCCEEEEEEHEEECCCCCCC
DHKASVTPEELTLLCQGIRAVEQALGSHDKLVTNSERKNKIVARKSIVAKFDIKKGDVFT
CCCCCCCHHHHHHHHHHHHHHHHHHCCCCCEECCCHHHHHHHHHHHHHEEEECCCCCEEE
LDNITTKRPGNGISPMSWYEVLGKTAEQDFSEDQLIAHSEFVAQEV
ECCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]